Cirugia Y Cirujanos最新文献_第8页

Dynamic changes and clinic significance of serum high mobility group box 1 in patients with total hip arthroplasty. 全髋关节置换术患者血清高迁移率组1的动态变化及临床意义。

IF 0.5 4区医学

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI: 10.24875/CIRU.22000238

Guangfu Zhou, Mao Liu, Xulin Wu, Bensen Tang

{"title":"Dynamic changes and clinic significance of serum high mobility group box 1 in patients with total hip arthroplasty.","authors":"Guangfu Zhou, Mao Liu, Xulin Wu, Bensen Tang","doi":"10.24875/CIRU.22000238","DOIUrl":"https://doi.org/10.24875/CIRU.22000238","url":null,"abstract":"Background: Deeper understanding on the risk factors and seeking potential predicted biomarkers for prognosis of total hip arthroplasty (THA) patients are of great significance. Limited researches focused the correlation between high mobility group box protein-1 (HMGB1) and the prognosis of THA patients.Objective: The objective of this study was to investigate the role of HMGB1 and inflammatory factors in patients underwent total hip arthroplasty (THA).Methods: The present prospective study enrolled 208 THA patients who went to our hospital during January 2020 to January 2022. Serum levels of HMGB1, C-reactive protein (CRP), interleukin-1b (IL-1β), and IL-6 were detected at the admission, 1 day, 3 days, 7 days, 30 days, and 90 days after surgery. The levels of Harris score, Fugl-Meyer, 36-item short-form health survey (SF-36), and Pittsburgh sleep quality index (PSQI) were detected on 90 days after surgery in two groups. Receiver operating characteristic curve (ROC) was performed for analyzing the diagnostic value of HMGB1 and logistic regression model was used for identifying the risk factor for poor prognosis of THA patients.Results: Serum levels of HMGB1 and inflammatory factors increased after surgery compared with the baselines. A positive correlation was found between HMGB1 and CRP on 1 day after surgery, and positive correlations were found among HMGB1, IL-1β, and IL-6 on 3 day after surgery. Besides, low HMGB1 reduced the incidence of post-operative complications and improved prognosis of THA patients.Conclusion: Serum HMGB1 was correlated with inflammatory factors and the prognosis of THA patients.","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 3","pages":"304-311"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9811336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Analysis of clinical outcomes of arteriovenous fistula for hemodialysis access in a Mexican elderly population. 墨西哥老年人群血液透析通道动静脉瘘的临床结果分析。

IF 0.5 4区医学

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI: 10.24875/CIRU.22000217

Emmanuel Contreras-Jimenez, Gabriel Lopez-Pena, Christopher Ruben-Castillo, Santiago Mier Y Teran-Ellis, Cesar Cuen-Ojeda, Luis H Arzola-Flores, Javier E Anaya-Ayala, Carlos A Hinojosa

{"title":"Analysis of clinical outcomes of arteriovenous fistula for hemodialysis access in a Mexican elderly population.","authors":"Emmanuel Contreras-Jimenez, Gabriel Lopez-Pena, Christopher Ruben-Castillo, Santiago Mier Y Teran-Ellis, Cesar Cuen-Ojeda, Luis H Arzola-Flores, Javier E Anaya-Ayala, Carlos A Hinojosa","doi":"10.24875/CIRU.22000217","DOIUrl":"https://doi.org/10.24875/CIRU.22000217","url":null,"abstract":"Objective: The increased survival rates of end-stage renal disease (ESRD) patients have impacted directly in the proportion of elderly patients requiring a reliable hemodialysis (HD) access; this group clearly demands an individualized approach. We aim to analyze maturation and patency rates of arteriovenous fistulas (AVF) in elderly patients.Methods: This was retrospective review of a database of patients that underwent AVF creation in our institution. The maturation and patency rates were analyzed divided in groups based on age (equal and greater of 65 years, and patients under 65 years). Patency rates were compared using Kaplan-Meier analysis.Results: Twenty patients ≥ 65 years old (mean 73, SD ± 5.4) were analyzed. The overall maturation rate in this group was 75% compared to 84.1% (p = 0.33) in the younger group (mean age 48 years, SD ± 17). The primary patency at 6 and 12 months for the ≥ 65 years group was 93% and 86%, respectively, compared with 85% and 81% for the younger group (p = 0.77).Conclusion: Autogenous AVF remains the preferred and durable option for elderly patients. We found no difference in terms of maturation and patency rates compared to younger patients. Standardized protocols are needed to optimally select vascular accesses.","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 2","pages":"200-203"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9477337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research designs starting from effects. 研究设计从效果出发。

IF 0.5 4区医学

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI: 10.24875/CIRU.22000542

Virgilio Lima-Gómez

引用次数: 0

Usefulness of immunohistochemical markers of myoepithelial cells in the diagnosis of invasive carcinoma of the breast. 肌上皮细胞免疫组织化学标志物在乳腺浸润性癌诊断中的价值。

IF 0.5 4区医学

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI: 10.24875/CIRU.22000174

Pablo S Montes-Arcón

引用次数: 0

Behind COVID-19 pandemic backstage: anxiety and healthcare workers. COVID-19大流行背后:焦虑和医护人员。

IF 0.5 4区医学

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI: 10.24875/CIRU.22000418

Selman Kızılkaya, Altuğ Çağatay

{"title":"Behind COVID-19 pandemic backstage: anxiety and healthcare workers.","authors":"Selman Kızılkaya, Altuğ Çağatay","doi":"10.24875/CIRU.22000418","DOIUrl":"https://doi.org/10.24875/CIRU.22000418","url":null,"abstract":"Background: COVID- 19 disease causes serious anxiety in healthcare workers.Objective: This study was carried out to determine the relationship between the anxiety level of epidemic diseases and occupational satisfaction.Method: The \"Disease Anxiety Scale,\" which consists of four subgroups and a total of 18 questions, and the \"Vocational Satisfaction Scale,\" which consists of two subgroups and 20 questions, were utilized to investigate the relationship between epidemic disease anxiety and occupational satisfaction. The statistical analysis was performed using the SPSS 26.0 program.Results: A total of 395 nurses were included in the study. The mean age of the participants was 33, and 63% were women. About 35.4% of the participants had deaths due to the COVID-19 pandemic in their family or close environment. It was determined that 83% of the nurses have a pandemic disease anxiety. Occupational satisfaction and epidemic anxiety level (p = 0.005, r = 0.560), pandemic (p = 0.01, r = 0.525), economic (p = 0.001, r = -0.473), quarantine (p = 0.003, r = -0.503), and social life (p = 0.003, r = -0.507) were found to be negatively correlated. There was no significant difference between job satisfaction (t = 0.286, p = 0.08) and epidemic anxiety (t = 1.312, p = 0.06) in terms of gender.Conclusion: Most health-care professionals experience serious anxiety, especially during the pandemic period.","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 2","pages":"247-252"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9774776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outcomes of tracheostomies performed in COVID-19 positive patients at Hospital Central del Estado Chihuahua, Mexico. 墨西哥奇瓦瓦州中央医院COVID-19阳性患者气管切开术的结果

IF 0.5 4区医学

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI: 10.24875/CIRU.20001342

Irving A Aponte-De la Rosa, Ma Isabel Saad-Manzanera, Jesús Solís-Valdez, Luis B Enríquez-Sánchez, Margarita A Fabela-Lozano, Javier A Guevara-López

{"title":"Outcomes of tracheostomies performed in COVID-19 positive patients at Hospital Central del Estado Chihuahua, Mexico.","authors":"Irving A Aponte-De la Rosa, Ma Isabel Saad-Manzanera, Jesús Solís-Valdez, Luis B Enríquez-Sánchez, Margarita A Fabela-Lozano, Javier A Guevara-López","doi":"10.24875/CIRU.20001342","DOIUrl":"https://doi.org/10.24875/CIRU.20001342","url":null,"abstract":"Objective: Provide a description of clinical characteristics, associated factors and outcome of tracheostomies performed in COVID-19 patients.Method: Observational prospective study of 14 patients who underwent tracheostomy. 10 of them were diagnosed with COVID 19, confirmed with RT-PCR test of nasopharyngeal exudate and compatible tomographic findings.Results: Of the 10 patients, five were discharged and five died. The average age of patients who died was 66.6 years; of those who were discharged, it was 60.4 years. Ventilatory parameters cut was taken as FiO2 ≤ 40% and PEEP ≤ 8; of the patients discharged, four met both criteria. On the other hand, of the patients who died, neither met both. Of the latter, an average of APACHE II of 16.4 and SOFA 7.4 were documented, while in discharged patients an average of 12.6 and 4.6 were observed, respectively.Conclusions: Tracheostomy performed in patients with specific criteria, such as low ventilatory parameters, age, or low score in severity scales, may have a better prognosis.","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 2","pages":"253-261"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9791018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of sitagliptin on down-regulation of KAT7 and SIRT1 gene expression in breast cancer cell line MCF7. 西格列汀下调乳腺癌细胞系MCF7中KAT7和SIRT1基因表达的影响。

IF 0.5 4区医学

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI: 10.24875/CIRU.22000189

Tanya C Ruteaga-Navarro, Miguel A Reyes-Romero, Quitzia L Torres-Salazar

{"title":"Effect of sitagliptin on down-regulation of KAT7 and SIRT1 gene expression in breast cancer cell line MCF7.","authors":"Tanya C Ruteaga-Navarro, Miguel A Reyes-Romero, Quitzia L Torres-Salazar","doi":"10.24875/CIRU.22000189","DOIUrl":"https://doi.org/10.24875/CIRU.22000189","url":null,"abstract":"Background: To date, the main clinical interest in DPP4 is focused on its inhibition in diabetic patients to prolong the half-life of incretins. Epigenetic alterations resulting from DPP4 inhibition have been poorly explored.Objective: The objective of this study was to determine, whether sitagliptin, a DPP4 inhibitor, has effects on the expression of KAT7 and SIRT1 (genes encoding a histone acetyltransferase and a histone deacetylase, respectively) in MCF7 breast cancer cells, which play an essential role in modulating the epigenetic landscape of chromatin.Material and methods: MCF7 cells were incubated for 20 h with sitagliptin at concentrations of 0.5, 1.0 and 2.0 μM. Total RNA was isolated and the relative mRNA expression of KAT7 and SIRT1 was determined by RT-qPCR.Results: There was downregulation in the relative expression of both genes; for KAT7, downregulation reached up to 0.49 (p = 0.027) and for SIRT1, it reached up to 0.55 (p = 0.037).Conclusions: These results suggest that sitagliptin has effects on the histone epigenetic landscape. This topic deserves further study due to the current sample use of DPP4 inhibitors in diabetic patients.","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 3","pages":"334-338"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9811341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Salivary gland tumor incidence in adult patients in a tertiary hospital in Mexico from 2008 to 2019. 2008 - 2019年墨西哥某三级医院成年患者唾液腺肿瘤发病率分析

IF 0.5 4区医学

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI: 10.24875/CIRU.21000414

Anuar Kuri-García, Aarón Kuri-García, Alberto Guakil-Haber, Erasmo González-Arciniega, Benjamín García-Enríquez

{"title":"Salivary gland tumor incidence in adult patients in a tertiary hospital in Mexico from 2008 to 2019.","authors":"Anuar Kuri-García, Aarón Kuri-García, Alberto Guakil-Haber, Erasmo González-Arciniega, Benjamín García-Enríquez","doi":"10.24875/CIRU.21000414","DOIUrl":"https://doi.org/10.24875/CIRU.21000414","url":null,"abstract":"Objective: To determine the incidence of salivary gland tumors in a population of a tertiary hospital in the State of Mexico, and to describe demographic variables.Method: An observational, cross-sectional and retrospective study of salivary gland tumors reported in a tertiary hospital in the State of Mexico in the period 2008-2019 is presented.Results: A prevalence of 0.049% was found. There was no difference between sex in the studied population. Benign salivary gland tumors were the most frequent (86.7%). The age range most affected was 51-60 years. The most frequently found tumor was the pleomorphic adenoma, followed by Warthin's tumor. There was 13.33% of sialolipomas, and one myoepithelioma. There were no cases of sublingual gland tumors or minor salivary glands.Conclusion: Tumors of the major salivary glands are infrequent tumors; population cases from a central Mexican state and their demographic characteristics are presented to contribute to the information found in local and international literature.","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 4","pages":"521-527"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10199845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of skeletal muscle area and prognostic nutritional index in periampullary tumors. 壶腹周围肿瘤骨骼肌面积及营养指标对预后的影响。

IF 0.5 4区医学

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI: 10.24875/CIRU.21000563

Gizem Kilinc-Tuncer, Ismail Sert, Korhan Tuncer, Orkun Sarioglu, Degercan Yesilyurt, Cem Karaali, Mustafa Emiroglu

{"title":"Effect of skeletal muscle area and prognostic nutritional index in periampullary tumors.","authors":"Gizem Kilinc-Tuncer, Ismail Sert, Korhan Tuncer, Orkun Sarioglu, Degercan Yesilyurt, Cem Karaali, Mustafa Emiroglu","doi":"10.24875/CIRU.21000563","DOIUrl":"https://doi.org/10.24875/CIRU.21000563","url":null,"abstract":"Introduction: The skeletal muscle area (SMA) and prognostic nutritional index (PNI) are both considered as predictive parameters for mortality and morbidity for various type of cancer. In this study, we aimed to identify the effects of pre-operative SMA and PNI values on post-operative mortality and morbidity in patients with periampullary region tumors (PRT).Methods: Patients between 2010 and 2020 were retrospectively analyzed and divided into two groups according to SMA and PNI cutoff values. Univariate and multivariate analysis was performed to find potential risk factors.Results: The mean age was 65.94 ± 11.242 and 54 (60.6%) of the patients were male. Hypertension was found a reducing factor for morbidity in both univariate and multivariate analysis (p = 0.039; p = 0.045). Chronic obstructive pulmonary disease and low PNI were found as factors affecting mortality in univariate analysis (p = 0.046; p = 0.014). However, only low PNI was found as an enhancing factor for mortality in multivariate analysis.Conclusion: Although SMA is not a risk factor for post-operative morbidity and mortality, PNI can be considered as a risk factor for mortality in patients with PRT.","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 1","pages":"73-78"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10720081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Colonoscopia como opción terapéutica ante rectorragia aguda tras sigmoidectomía. 结肠镜检查是乙状结肠切除术后急性直肠出血的治疗选择。

IF 0.5 4区医学

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI: 10.24875/CIRU.22000096

Araceli Moreno-Navas, Irene Gómez-Luque, César Díaz-López, Javier Briceño-Delgado

引用次数: 0