Rosario Losiggio, Martina Baiardo Redaelli, Giovanni Landoni, Rinaldo Bellomo
{"title":"Amino Acid Infusion and Renal Protection: Beyond Hemodynamic Optimization in Cardiac Surgery.","authors":"Rosario Losiggio, Martina Baiardo Redaelli, Giovanni Landoni, Rinaldo Bellomo","doi":"10.1016/j.athoracsur.2025.03.019","DOIUrl":"https://doi.org/10.1016/j.athoracsur.2025.03.019","url":null,"abstract":"","PeriodicalId":50976,"journal":{"name":"Annals of Thoracic Surgery","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesco Onorati, Daniela Geisler, Alexis Theron, Alessandra Francica, Vincenzo Caruso, Carlo Mariani, Antonio Fiore, Romy Hegeman, Alizee Porto, Thierry Folliguet, Gianluca Lucchese, Patrick Klein, Davide Pacini, Martin Grabenwöger, Giovanni Battista Luciani
{"title":"Five-year Results of Aortic Valve Replacement with a Novel Bioprosthesis: Real-world data from a large multicenter registry.","authors":"Francesco Onorati, Daniela Geisler, Alexis Theron, Alessandra Francica, Vincenzo Caruso, Carlo Mariani, Antonio Fiore, Romy Hegeman, Alizee Porto, Thierry Folliguet, Gianluca Lucchese, Patrick Klein, Davide Pacini, Martin Grabenwöger, Giovanni Battista Luciani","doi":"10.1016/j.athoracsur.2025.03.015","DOIUrl":"https://doi.org/10.1016/j.athoracsur.2025.03.015","url":null,"abstract":"<p><strong>Background: </strong>The clinical performance and safety of a glutaraldehyde-free bioprosthetic valve using a novel tissue treatment in a large real-world patient population has not been previously reported.</p><p><strong>Methods: </strong>This is a prospective, multi-centre, real-world registry of all-comer patients undergoing surgical aortic valve replacement (SAVR) using a novel bioprosthesis at seven European cardiac surgery centres. The primary endpoint was the five-year freedom from structural valve deterioration (SVD) as per VARC-3 criteria. Secondary endpoints included hemodynamic performance of the bioprosthesis and freedom from all-cause and cardiovascular mortality, prosthetic endocarditis, stroke, and reintervention at 5 years.</p><p><strong>Results: </strong>A total of 498 patients were included in the analysis; the mean age was 60.1 years with a mean EuroSCORE II of 3.9% and 27.9% being female. The median follow-up was 4.8 years. Five-year freedom from SVD Stages 1, 2 and 3 were 95.7%, 98.6%, and 99.3%, respectively. The estimated 5-year overall survival was 93.2%, while freedom from cardiovascular mortality was 97.2%. Event-free probabilities at 5 years for endocarditis, stroke and reintervention were 98.6%, 98.1%, and 98.2%, respectively. Moderate/severe paravalvular leakage was infrequent (97.3% event-free probability at 5 years) and mean aortic valve pressure gradient was stable compared to discharge (median 11.0 mmHg at discharge vs 12.0 mmHg at 5 years).</p><p><strong>Conclusions: </strong>These real-world clinical data of a novel aortic bioprosthesis demonstrated good 5-year results for both durability and safety outcomes as well as stable hemodynamic valve performance.</p>","PeriodicalId":50976,"journal":{"name":"Annals of Thoracic Surgery","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Standardizing Analyses in the Society of Thoracic Surgeons Adult Cardiac Surgery Database.","authors":"J Hunter Mehaffey, S Ram Kumar","doi":"10.1016/j.athoracsur.2025.03.016","DOIUrl":"https://doi.org/10.1016/j.athoracsur.2025.03.016","url":null,"abstract":"","PeriodicalId":50976,"journal":{"name":"Annals of Thoracic Surgery","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ten Years' Experience of Surgical Treatment with Modified Triple-Branched Stent Graft for Type A Aortic Dissection.","authors":"Qingsong Wu, Debin Jiang, Yue Shen, Guanhua Fang, Zhihuang Qiu, Liangwan Chen","doi":"10.1016/j.athoracsur.2025.03.006","DOIUrl":"https://doi.org/10.1016/j.athoracsur.2025.03.006","url":null,"abstract":"<p><strong>Background: </strong>In the past decade, modified triple-branched stent grafts have emerged as a promising treatment option for total aortic arch replacement surgery for type A aortic dissection (TAAD). In this study, we present our original contributions and clinical experiences with this surgical technique over the last 10 years.</p><p><strong>Methods: </strong>We retrospectively analyzed patients who underwent total aortic arch replacement surgery for TAAD using modified triple-branched stent grafts between September 2012 and September 2022, collecting and analyzing all related data.</p><p><strong>Results: </strong>In total, 479 patients with a mean age of 53 years and a male predominance of 60.5% were enrolled. The thirty-day mortality was 4.8% (23/479 patients). Early postoperative complications were observed in 42 (8.8%) patients. An average follow-up period of 72 months resulted in a survival rate of 83.1% (353/425); 31 patients were lost to follow-up (6.8%). The false aortic lumen thrombosis rate was 79.3%. Stent-related complications occurred in 34 cases, with 3 of these cases consequently requiring reoperation. However, stent-related complications did not affect mortality or morbidity during follow-up. Of the patients, 46 (10.8%) had negative remodeling of aortic dissection, 20 underwent surgery because of a dissecting aneurysm, and 8 died of aortic rupture.</p><p><strong>Conclusions: </strong>Our 10-year experience with modified triple-branched stent grafts for the surgical treatment of TAAD demonstrated the promising results of this technique, indicating that it provides a feasible and convenient alternative to traditional surgical methods, with clear long-term effectiveness and safety.</p>","PeriodicalId":50976,"journal":{"name":"Annals of Thoracic Surgery","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Updated post-recurrence survival outcomes in patients undergoing pleurectomy/decortication for pleural mesothelioma: A retrospective study.","authors":"Akifumi Nakamura, Masaki Hashimoto, Ayumi Kuroda, Kyoshiro Takegahara, Akihiro Fukuda, Seiji Matsumoto, Nobuyuki Kondo, Takashi Kijima, Seiki Hasegawa, Soichiro Funaki","doi":"10.1016/j.athoracsur.2025.03.014","DOIUrl":"https://doi.org/10.1016/j.athoracsur.2025.03.014","url":null,"abstract":"<p><strong>Background: </strong>Pleural mesothelioma remains a challenging disease with a high recurrence rate despite multimodality treatment. We previously described clinical outcomes associated with post-pleurectomy/decortication recurrence in pleural mesothelioma. In this study, we aimed to update these results using data from a larger, more recent cohort and to identify prognostic factors influencing post-recurrence survival after pleurectomy/decortication.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study involving 251 patients who underwent neoadjuvant chemotherapy with platinum plus pemetrexed, followed by pleurectomy/decortication from January 2012 to December 2022. We calculated survival and recurrence rates using the Kaplan-Meier method and the log-rank test, respectively. Multivariable analysis with the Cox proportional hazards model was used to assess clinical factors related to post-recurrence survival.</p><p><strong>Results: </strong>Of the 251 patients, 190 (75.7%) experienced recurrence (median follow-up, 30.9 months). The 2-year recurrence-free and overall survival rates were 37.3% (median, 21.1 months) and 72.3% (median, 44.1 months), respectively. The 1-year post-recurrence survival rate was 60.6% (median, 18.0 months). Multivariable analysis revealed that post-recurrence treatment (hazard ratio [HR], 0.12; 95% confidence interval [CI], 0.071-0.22; P < 0.0001), local recurrence (HR, 0.45; 95% CI, 0.31-0.66; P < 0.0001), age at recurrence < 70 years (HR, 0.53; 95% CI, 0.37-0.76; P = 0.0007), and disease-free interval > 12 months (HR, 0.43; 95% CI, 0.28-0.65; P < 0.0001) were independent, favorable, and significant prognostic factors of post-recurrence survival.</p><p><strong>Conclusions: </strong>Post-recurrence treatment, recurrence pattern, age at recurrence, and disease-free interval significantly influence post-recurrence survival, indicating favorable outcomes in patients undergoing pleurectomy/decortication.</p>","PeriodicalId":50976,"journal":{"name":"Annals of Thoracic Surgery","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Blood Pressure and Heart Rate Control After Aortic Dissection Repair: Questions and Future Directions.","authors":"Reda Rhellab, Johanna J M Takkenberg","doi":"10.1016/j.athoracsur.2025.03.012","DOIUrl":"https://doi.org/10.1016/j.athoracsur.2025.03.012","url":null,"abstract":"","PeriodicalId":50976,"journal":{"name":"Annals of Thoracic Surgery","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J Michael DiMaio, Kyle A McCullough, Emily Shih, William T Brinkman
{"title":"The Renaissance of the Ross Procedure.","authors":"J Michael DiMaio, Kyle A McCullough, Emily Shih, William T Brinkman","doi":"10.1016/j.athoracsur.2025.03.013","DOIUrl":"https://doi.org/10.1016/j.athoracsur.2025.03.013","url":null,"abstract":"","PeriodicalId":50976,"journal":{"name":"Annals of Thoracic Surgery","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aaron M Williams, Brian Lima, Swaroop Bommareddi, John M Trahanas
{"title":"Cardiac Allocation version 4.2: Should Heart Allocation Update Like Your Smartphone?","authors":"Aaron M Williams, Brian Lima, Swaroop Bommareddi, John M Trahanas","doi":"10.1016/j.athoracsur.2025.03.017","DOIUrl":"https://doi.org/10.1016/j.athoracsur.2025.03.017","url":null,"abstract":"","PeriodicalId":50976,"journal":{"name":"Annals of Thoracic Surgery","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}