{"title":"Pediatric retinal detachment: Anatomical and visual outcomes from tertiary eye center in Nepal","authors":"S. Pradhan, S. Ranabhat, S. Khadka, R. Byanju","doi":"10.4103/pajo.pajo_100_23","DOIUrl":"https://doi.org/10.4103/pajo.pajo_100_23","url":null,"abstract":"\u0000 \u0000 \u0000 The aim is to evaluate the anatomical and functional outcomes of retinal detachment (RD) surgery in the pediatric population in a tertiary eye hospital in Nepal.\u0000 \u0000 \u0000 \u0000 This study is a hospital-based, retrospective cross-sectional study, including patients under 18 years of age, diagnosed with rhegmatogenous RD (RRD) for 5 years from January 2015 to December 2019, who underwent RD surgery.\u0000 \u0000 \u0000 \u0000 Twenty patients were included in the study (mean age of 10.75 ± 2.63). Male patients were 19 (95%). A history of trauma was seen in 13 (65%) patients. Phakic RRD was observed in 18 (90%) patients and the rest 2 (10%) patients were pseudophakic. Type B proliferative vitreoretinopathy changes were observed in 3 (15%) patients, type C was observed in single patient (5%). Scleral buckling was performed in 7 (35%) patients, while 12 (60%) patients underwent three-port pars plana vitrectomy (PPV) and silicon oil instillation and the remaining single patient (5%) underwent PPV with gas exchange. Lensectomy was performed in 8 (40%) patients. Retinal attachment with a single surgical procedure was seen in 8 (40%) patients, while 12 (60%) patients required multiple surgeries. The mean duration of silicon oil removal was 5 ± 2.78 months (1–11 months). At the end of 6 months, 11 (55%) patients had improved visual acuity of 6/60. Six months postoperatively, 18 (90%) patients had attached retina.\u0000 \u0000 \u0000 \u0000 Visual improvement and retinal reattachment could be achieved with early diagnosis and intervention in pediatric RRD.\u0000","PeriodicalId":508483,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140404547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah Cristina Garcia Gomes, B. Patrús, Jéssica Thais Lopes, L. B. de Sousa
{"title":"Ocular sporotrichosis in a pregnant woman","authors":"Sarah Cristina Garcia Gomes, B. Patrús, Jéssica Thais Lopes, L. B. de Sousa","doi":"10.4103/pajo.pajo_81_23","DOIUrl":"https://doi.org/10.4103/pajo.pajo_81_23","url":null,"abstract":"\u0000 The objective was to report a rare case of ocular sporotrichosis in Fundação Banco de Olhos de Goiás. A 29-year-old pregnant woman presented with Parinaud’s oculoglandular syndrome. She referred to contact with a sick cat. The patient was submitted to a conjunctival culture and skin nodule biopsy, which revealed sporotrichosis. This report discussed this rare case of sporotrichosis presentation in the city of Goiania, Goiás state, Brazil.","PeriodicalId":508483,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"10 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140401134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eric Pinheiro de Andrade, Camila Matsuura Endo, Patrick Israel Fligelman Kanas, Lisângela Morimoto, M. N. Aidar, Júlia Cristina Oliveira e Lima, Diovani Costa Madeira, Yasmin Tournier Boppré, A. C. Kara-José, Henrique Ballalai Ferraz, R. Saba, Ivan Maynart Tavares
{"title":"Influence of age on the thickness of retinal nerve fiber layer in patients with mild-to-moderate stages of Parkinson’s disease: Case series","authors":"Eric Pinheiro de Andrade, Camila Matsuura Endo, Patrick Israel Fligelman Kanas, Lisângela Morimoto, M. N. Aidar, Júlia Cristina Oliveira e Lima, Diovani Costa Madeira, Yasmin Tournier Boppré, A. C. Kara-José, Henrique Ballalai Ferraz, R. Saba, Ivan Maynart Tavares","doi":"10.4103/pajo.pajo_110_23","DOIUrl":"https://doi.org/10.4103/pajo.pajo_110_23","url":null,"abstract":"\u0000 \u0000 \u0000 Parkinson’s disease, a neurodegenerative disease, involves motor and nonmotor components. Vision, a nonmotor component, has been studied by the analysis of the retinal layers by optical coherence tomography (OCT), and the main finding is the thinning of the retinal nerve fiber layer (RNFL). The aim of this study was to verify the influence of age on the thickness of retinal nerve fiber in patients with mild-to-moderate stages of Parkinson’s disease.\u0000 \u0000 \u0000 \u0000 Healthy individuals and patients with Parkinson’s disease were included in this prospective, cross-sectional, and observational study. The patients were recruited according to the clinical criteria from the neurology clinic of two major hospitals, with the description of the Hoehn and Yahr scale score. Healthy subjects were recruited from the general clinic and hospital staff. A comprehensive ophthalmic examination was performed previously on the spectral-domain OCT.\u0000 \u0000 \u0000 \u0000 There was a significant effect of age in the thickness of the RNFL in patients with Parkinson’s disease, in the right eye in the lower quadrant (P = 0.026) and in the left eye in the upper (P = 0.029) and temporal (P = 0.037) quadrants, as well in the control group in the upper (P = 0.003) and lower quadrant (P = 0.024).\u0000 \u0000 \u0000 \u0000 This case series could demonstrate that in mild-to-moderate stages of the Hoehn and Yahr Scale, there is an asymmetric correlation between aging and the decrease in superior, inferior, and temporal RNFL between the eyes of patients with Parkinson’s disease, and this finding precedes the decrease in visual acuity.\u0000","PeriodicalId":508483,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140406488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Orbital cellulitis with exudative retinal detachment: A rare finding","authors":"Ishita Bajaj, Jolly Rohatgi, Rajender Prasad","doi":"10.4103/pajo.pajo_96_23","DOIUrl":"https://doi.org/10.4103/pajo.pajo_96_23","url":null,"abstract":"\u0000 Orbital cellulitis is a rare cause of exudative retinal detachment (ERD). We hereby present a case of orbital cellulitis associated with ERD from North India. A 42-year-old man presented with features of orbital cellulitis in the left eye for 3 days. An ERD lesion was found in the superior-temporal quadrant of the retina of the same eye. Investigations were performed; however, the cause of orbital cellulitis could not be found. Systemic antibiotics were started, leading to improved orbital cellulitis and resolution of ERD. Orbital cellulitis can be treated with systemic antibiotics. The cure of underlying disease leads to the resolution of ERD.","PeriodicalId":508483,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"27 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140401857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anelise Savaris Dias, J. Burnier, Sabrina Bergeron, Emma Youhnovska, Emily Marcotte, Rubens N Belfort, MiguelN Burnier
{"title":"Diagnosis and histopathological evaluation of soft drusen in patients that underwent evisceration and enucleation","authors":"Anelise Savaris Dias, J. Burnier, Sabrina Bergeron, Emma Youhnovska, Emily Marcotte, Rubens N Belfort, MiguelN Burnier","doi":"10.4103/pajo.pajo_49_23","DOIUrl":"https://doi.org/10.4103/pajo.pajo_49_23","url":null,"abstract":"\u0000 \u0000 \u0000 Drusen are yellow deposits between the basal lamina of the retinal pigment epithelium and the inner collagenous layer of Bruch’s membrane. Soft drusen, generally characterized by a medium to large size and poorly demarcated boundaries, increases the risk for advanced age-related macular degeneration (AMD). The prevalence of soft drusen in histopathological sections of the macular region, obtained from enucleated and eviscerated eyes, will be correlated in this study.\u0000 \u0000 \u0000 \u0000 This is a prospective cross-sectional study performed at the MUHC-McGill University Ocular Pathology and Translational Research Laboratory (McGill University, Montreal, Canada). A total of 158 eyes were evaluated between 2011 and 2019. Of these, 50% were enucleated and 50% eviscerated eyes. Cases were divided by age in decades into both groups, eviscerated and enucleated eyes. Inclusion criteria were patients aged 50 years or older, identification by histological criteria of macular area, histopathologically preserved macular area, presence of sufficient residual tissue for additional sections, and concrete patient data. The histopathological review was performed in digitized H and E slides (ZEISS Axio Scan.Z1) to assess the presence of soft drusen.\u0000 \u0000 \u0000 \u0000 The results in both groups, enucleated and eviscerated eyes, were similar, as well as the histopathological criteria used in the analysis of soft drusen.\u0000 \u0000 \u0000 \u0000 Prevalence of AMD in the referred population was comparable to that described in both studied groups.\u0000","PeriodicalId":508483,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"9 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140425112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giovanna Provenzano, J. Burnier, Sabrina Bergeron, Emma Youhnovska, Emily Marcotte, John Chen, Vincent Sun, MiguelN Burnier
{"title":"The value of diagnostic vitrectomy: Histocytopathology techniques for the diagnosis of lymphoma of the retina","authors":"Giovanna Provenzano, J. Burnier, Sabrina Bergeron, Emma Youhnovska, Emily Marcotte, John Chen, Vincent Sun, MiguelN Burnier","doi":"10.4103/pajo.pajo_44_23","DOIUrl":"https://doi.org/10.4103/pajo.pajo_44_23","url":null,"abstract":"\u0000 \u0000 \u0000 Primary large B-cell lymphoma of the retina, vitreous, and central nervous system (CNS), is an intraocular tumor with an unspecific and insidious clinical presentation. Pars plana vitrectomy (PPV) and optical coherence tomography (OCT) are useful diagnostic tools for this malignant process. The aim of this study is to evaluate the diagnostic efficacy of PPV for these intraocular lesions under a modified diagnostic protocol with a clinical pathological correlation with OCT imaging.\u0000 \u0000 \u0000 \u0000 A total of 115 samples were collected after a vitrectomy procedure (aspiration or vitrectomy cassette). The samples were centrifuged, and the precipitates were collected. A cell block was prepared and analyzed with multiple stains and an immunohistochemistry (IHC) panel, including B- and T-cell markers, as well as light chain markers, to establish the monoclonal nature of the tumor. Of the 115 samples, 9 (7.83%) were diagnosed with large B-cell lymphoma of the retina, vitreous, and CNS.\u0000 \u0000 \u0000 \u0000 Diagnostic vitrectomies for the large B-cell lymphoma of the retina, vitreous, and CNS is an excellent tool for the diagnosis of this entity. A negative diagnostic PPV with a strong suspicious OCT image, where the neoplastic cells are located between the retinal pigmented epithelium and Bruch’s membrane, the latter procedure should be either repeated or a chorioretinal biopsy be performed. In contrast, a positive vitrectomy using the IHC panel for large B-cell lymphoma of the retina, vitreous, and CNS is pathognomonic of this condition. In addition, the OCT is an important tool to help in the diagnosis of this difficult entity.\u0000 \u0000 \u0000 \u0000 The diagnostic PPV provided suitable vitreous samples to all patients with undetermined uveitis and/or intraocular tumor suspicion. A morphological and immunohistichemical (IHC) analysis enabled a conclusive diagnosis of retina, vitreous and CNS lymphoma in all patients submitted to the procedure.\u0000","PeriodicalId":508483,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"47 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140464385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michellede Lima Farah, Samir Arbache, Rubens Belfort
{"title":"Response to comment on corneal drug delivery with tattoo technique","authors":"Michellede Lima Farah, Samir Arbache, Rubens Belfort","doi":"10.4103/pajo.pajo_3_24","DOIUrl":"https://doi.org/10.4103/pajo.pajo_3_24","url":null,"abstract":"","PeriodicalId":508483,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"167 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140470203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Margarida Baptista, C. Bruxelas, Miguel Cordeiro, Marta Guedes
{"title":"Human T-cell lymphotropic virus type 1-related uveitis, review about a case","authors":"Margarida Baptista, C. Bruxelas, Miguel Cordeiro, Marta Guedes","doi":"10.4103/pajo.pajo_105_23","DOIUrl":"https://doi.org/10.4103/pajo.pajo_105_23","url":null,"abstract":"\u0000 Human T-cell lymphotropic virus type 1 (HTLV-1) is an endemic retrovirus associated with adult T-cell leukemia/lymphoma (ATL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM-TSP), and HTLV-1 uveitis (HU). The latter may occur in association with HAM-TSP, more rarely along ATL, or as an isolated manifestation of the viral infection. The authors present a review of the literature on HU, illustrated by a clinical case. A literature search was performed in the MEDLINE database (PubMed) and included surveys completed until 2022. HU prevalence is increasing in nonendemic metropolitan areas due to migration, thus it is becoming an increasingly relevant agent in the differential diagnosis of patients with uveitis.","PeriodicalId":508483,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"25 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140519686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rita C Basto, Catarina Francisco, A. Silva, Ana Rita Viana, Renato Correia Barbosa, Sofia Teixeira, Catarina Cunha Ferreira, Carolina Madeira, Rui Carvalho, Carla Teixeira, Paula Tenedório
{"title":"Fluocinolone acetonide implant scleral fixation for cystoid macular edema in eyes with iris–lens diaphragm disruption","authors":"Rita C Basto, Catarina Francisco, A. Silva, Ana Rita Viana, Renato Correia Barbosa, Sofia Teixeira, Catarina Cunha Ferreira, Carolina Madeira, Rui Carvalho, Carla Teixeira, Paula Tenedório","doi":"10.4103/pajo.pajo_26_23","DOIUrl":"https://doi.org/10.4103/pajo.pajo_26_23","url":null,"abstract":"\u0000 This is a two-center, case series of three patients with postoperative refractory cystoid macular edema (CME) and disruption of the iris–lens diaphragm, submitted to scleral fixation of fluocinolone acetonide implant. All patients achieved successful CME reduction with visual acuity improvement. The surgical procedure was uneventful in all cases; however, one patient developed hypotony with leakage from the scleral tunnel, which was successfully resolved with reinforcement of the suture and injection of viscoelastics in the anterior chamber. No case of implant migration was observed and patients did not report any visual field disturbances. Our results emphasize this surgical technique as an effective and safe procedure for patients with persistent CME and disruption of the iris–lens diaphragm.","PeriodicalId":508483,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"112 3-4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140523347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Commentary: “To study the role of hematological biomarkers in type 2 diabetes patients with diabetic retinopathy”","authors":"Edgar Lozano-Cruz","doi":"10.4103/pajo.pajo_109_23","DOIUrl":"https://doi.org/10.4103/pajo.pajo_109_23","url":null,"abstract":"","PeriodicalId":508483,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"50 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140519192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}