Alternative Medicine Review最新文献_第8页

Iodine. Monograph. 碘。专著。

Alternative Medicine Review Pub Date : 2010-09-01

引用次数: 0

National Institutes of Health discover naturopathic principle. 国家卫生研究院发现自然疗法原理。

Alternative Medicine Review Pub Date : 2010-09-01

Davis W Lamson

引用次数: 0

Vitamins D and K as pleiotropic nutrients: clinical importance to the skeletal and cardiovascular systems and preliminary evidence for synergy. 维生素D和维生素K作为多效营养素:对骨骼和心血管系统的临床重要性和协同作用的初步证据。

Alternative Medicine Review Pub Date : 2010-09-01

Parris M Kidd

{"title":"Vitamins D and K as pleiotropic nutrients: clinical importance to the skeletal and cardiovascular systems and preliminary evidence for synergy.","authors":"Parris M Kidd","doi":"","DOIUrl":"","url":null,"abstract":"Vitamins D and K are lipid-phase nutrients that are pleiotropic - endowed with versatile homeostatic capacities at the organ, tissue, and cellular levels. Their metabolic and physiologic roles overlap considerably, as evidenced in the bone and cardiovascular systems. Vitamin D₃ (cholecalciferol, D₃) is the prehormone for the vitamin D endocrine system. Vitamin D₃ undergoes initial enzymatic conversion to 25-hydroxyvitamin D (25D, calcidiol), then to the seco-steroid hormone 1alpha, 25-dihydroxyvitamin D (1,25D, calcitriol). Beyond its endocrine roles in calcium homeostasis, 1,25D likely has autocrine, paracrine, and intracrine effects. At least 17 tissues likely synthesize 1,25D, and 35 carry the vitamin D receptor (VDR). Vitamin D functional deficiency is widespread in human populations. Vitamin K₁ (phylloquinone) is more abundant in foods but less bioactive than the vitamin K₂ menaquinones (especially MK-4, menatetrenone). Menadione (vitamin K₃) has minimal K activity. Vitamin K compounds undergo oxidation-reduction cycling within the endoplasmic reticulum membrane, donating electrons to activate specific proteins via enzymatic gamma-carboxylation of glutamate groups before being enzymatically re-reduced. Warfarin inhibits this vitamin K reduction, necessitating K supplementation during anticoagulation therapy. Along with coagulation factors (II, VII, IX, X, and prothrombin), protein C and protein S, osteocalcin (OC), matrix Gla protein (MGP), periostin, Gas6, and other vitamin K-dependent (VKD) proteins support calcium homeostasis, facilitate bone mineralization, inhibit vessel wall calcification, support endothelial integrity, are involved in cell growth control and tissue renewal, and have numerous other effects. This review updates vitamin D and K skeletal and cardiovascular benefits and evidence for their synergy of action.","PeriodicalId":50821,"journal":{"name":"Alternative Medicine Review","volume":"15 3","pages":"199-222"},"PeriodicalIF":0.0,"publicationDate":"2010-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29533440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Testing the blood of autistic children for ammonia. 检测自闭症儿童血液中的氨含量。

Alternative Medicine Review Pub Date : 2010-09-01

Peter Good

引用次数: 0

A review of the sirtuin system, its clinical implications, and the potential role of dietary activators like resveratrol: part 1. 综述sirtuin系统，其临床意义，以及白藜芦醇等膳食激活剂的潜在作用:第一部分。

Alternative Medicine Review Pub Date : 2010-09-01

Gregory Kelly

{"title":"A review of the sirtuin system, its clinical implications, and the potential role of dietary activators like resveratrol: part 1.","authors":"Gregory Kelly","doi":"","DOIUrl":"","url":null,"abstract":"The silent information regulator (SIR) genes (sirtuins) comprise a highly conserved family of proteins, with one or more sirtuins present in virtually all species from bacteria to mammals. In mammals seven sirtuin genes - SIRT1 to SIRT7 - have been identified. Emerging from research on the sirtuins is a growing appreciation that the sirtuins are a very complicated biological response system that influences many other regulator molecules and pathways in complex manners. Responses of this system to environmental factors, as well as its role in health and disease, are currently incompletely characterized and at most partially understood. This article reviews the mammalian sirtuin system, discusses the dietary, lifestyle, and environmental factors that influence sirtuin activity, and summarizes research on the importance of vitamin B3 in supporting sirtuin enzyme activity, as well as the role specifically of the amide form of this vitamin - nicotinamide - to inhibit sirtuin enzyme activity. Polyphenols, especially resveratrol, influence sirtuins. Existing evidence on these nutritional compounds, as they relate to the sirtuin system, is reviewed. In Part 2 of this review, clinical situations where sirtuins might play a significant role, including longevity, obesity, fatty liver disease, cardiovascular health, neurological disease, and cancer, are discussed.","PeriodicalId":50821,"journal":{"name":"Alternative Medicine Review","volume":"15 3","pages":"245-63"},"PeriodicalIF":0.0,"publicationDate":"2010-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29533442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pinch me, I must be dreaming. 掐我一下，我一定是在做梦。

Alternative Medicine Review Pub Date : 2010-09-01 DOI: 10.1108/eb038195

W. Crinnion

引用次数: 1

A case of MRSA controlled: predisposing factors and immune stimulation. MRSA控制1例:易感因素及免疫刺激。

Alternative Medicine Review Pub Date : 2010-07-01

Davis W Lamson, Angela E Sadlon

引用次数: 0

Resveratrol. Monograph. 白藜芦醇。专著。

Alternative Medicine Review Pub Date : 2010-07-01

引用次数: 0

Nutritional treatments for acute myocardial infarction. 急性心肌梗死的营养治疗。

Alternative Medicine Review Pub Date : 2010-07-01

Alan R Gaby

{"title":"Nutritional treatments for acute myocardial infarction.","authors":"Alan R Gaby","doi":"","DOIUrl":"","url":null,"abstract":"Acute myocardial infarction (MI) is one of the most frequent causes of death in the United States. The evaluation and treatment of acute MI in conventional medicine has focused primarily on anatomical and physiological factors that lead to impaired blood flow. Less attention has been paid to metabolic factors that may influence the vulnerability of the myocardium to ischemia and to various stressors. There is evidence that in some cases inefficient cellular metabolism, rather than the availability of oxygen and other blood-borne nutrients, is an important factor determining whether cardiac pathology will develop. Metabolic dysfunction could result from intracellular deficiencies of magnesium, coenzyme Q10, carnitine, and certain B vitamins, nutrients which play a role in the synthesis of adenosine triphosphate (ATP; the body's main storage form of energy). In addition, increased oxidative stress may contribute to the pathogenesis of both MI-related myocardial damage and reperfusion injury. Consequently, administration of antioxidants might improve outcomes in patients with acute MI. Numerous clinical trials have found parenteral administration of magnesium in the early stages of acute MI can substantially reduce the death rate. In addition, several trials have shown L-carnitine is beneficial in the treatment of acute MI. Other nutrients, such as vitamin C, vitamin E, and various B vitamins, may also be of value.","PeriodicalId":50821,"journal":{"name":"Alternative Medicine Review","volume":"15 2","pages":"113-23"},"PeriodicalIF":0.0,"publicationDate":"2010-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29278827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pterostilbene. Monograph. Pterosilbene。专著。

Alternative Medicine Review Pub Date : 2010-07-01

引用次数: 0