Frontiers in Oncology最新文献

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Case report: Translational treatment of unresectable intrahepatic cholangiocarcinoma: Tislelizumab, Lenvatinib, and GEMOX in one case 病例报告:无法切除的肝内胆管癌的转化治疗:Tislelizumab、Lenvatinib 和 GEMOX 在一个病例中的应用
Frontiers in Oncology Pub Date : 2024-07-15 DOI: 10.3389/fonc.2024.1428370
He-wei Zhang, Hai-bo Yu
{"title":"Case report: Translational treatment of unresectable intrahepatic cholangiocarcinoma: Tislelizumab, Lenvatinib, and GEMOX in one case","authors":"He-wei Zhang, Hai-bo Yu","doi":"10.3389/fonc.2024.1428370","DOIUrl":"https://doi.org/10.3389/fonc.2024.1428370","url":null,"abstract":"Intrahepatic cholangiocellular carcinoma (ICC) is one of the most common invasive malignancies. Currently, ICC is treated with radical surgical resection. However, the majority of patients are diagnosed at an advanced stage, making surgery ineligible for them.We present a case of advanced ICC, which could not undergo radical surgery due to tumor invasion of liver blood vessels. The gemcitabine and oxaliplatin (GEMOX) regimen combined with Tislelizumab immunotherapy and Lenvatinib targeted therapy for 8 cycles resulted in significant tumor shrinkage significantly and the vascular invasion disappeared. CA19–9 levels were reduced to normal levels. Partial remission and successful tumor transformation were achieved. The patient underwent a successful radical surgical resection, including cholecystectomy, resection of liver segments IV, V, and VIII, as well as a regional lymphatic dissection procedure, resulting in complete pathological remission.Tumor-free surgical margins (R0) resection of patients with advanced ICC after combination of immune, targeted and chemotherapy is rare, and there are almost no cases of complete postoperative remission. The GEMOX regimen in combination with Tislelizumab and Lenvatinib has a good antitumor efficacy and safety profile, and may be a feasible and safe translational treatment option for advanced ICC.","PeriodicalId":507440,"journal":{"name":"Frontiers in Oncology","volume":"20 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141647905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case report: 18F-FDG PET/CT skeletal superscan-like in an adult patient with acute lymphoblastic leukemia 病例报告:一名急性淋巴细胞白血病成人患者的 18F-FDG PET/CT 骨骼超扫描成像
Frontiers in Oncology Pub Date : 2024-07-15 DOI: 10.3389/fonc.2024.1401453
Yu Hu, Wenli Dai, Peng Wang, Yawen Feng, Hui Feng, Jun Li
{"title":"Case report: 18F-FDG PET/CT skeletal superscan-like in an adult patient with acute lymphoblastic leukemia","authors":"Yu Hu, Wenli Dai, Peng Wang, Yawen Feng, Hui Feng, Jun Li","doi":"10.3389/fonc.2024.1401453","DOIUrl":"https://doi.org/10.3389/fonc.2024.1401453","url":null,"abstract":"We herein describe a rare case of adult acute lymphoblastic leukemia with an 18florine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) skeletal superscan-like appearance. The degree of bone marrow uptake was so intense that it far exceeded the level of physiological cerebral uptake and radiourinary activity. The distribution was remarkably similar to a superscan seen on skeletal scintigraphy. Skeletal superscans of 18F-FDG PET/CT have been reported in hematological diseases, solid tumors with extensive bone metastasis, and metabolic diseases. Thus, we reviewed the PET/CT images of cases reported, indicating that more homogeneous distribution, without primary tumor and specific mandibular and skull activity, may be suggestive of hematological diseases.","PeriodicalId":507440,"journal":{"name":"Frontiers in Oncology","volume":"37 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141645104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Growing teratoma syndrome of the ovary: a case report and literature review 卵巢生长畸胎瘤综合征:病例报告和文献综述
Frontiers in Oncology Pub Date : 2024-07-15 DOI: 10.3389/fonc.2024.1412206
Jiaying Tao, Zhixian Shi, Mulan Li, Tingting Li
{"title":"Growing teratoma syndrome of the ovary: a case report and literature review","authors":"Jiaying Tao, Zhixian Shi, Mulan Li, Tingting Li","doi":"10.3389/fonc.2024.1412206","DOIUrl":"https://doi.org/10.3389/fonc.2024.1412206","url":null,"abstract":"Growing teratoma syndrome (GTS) is a rare condition that arises secondary to malignant germ cell tumors. It is characterized by an enlarging abdominal mass during or after chemotherapy, normal tumor markers, and histopathological indications of mature teratoma components. Awareness of GTS is limited, and it is often mistaken for disease progression or recurrence. This misdiagnosis can lead to delayed treatment and increased risk of complications. Therefore, early identification of GTS is crucial to avoid unnecessary systemic treatments and reduce financial burden. GTS is unresponsive to chemotherapy or radiotherapy and complete surgical resection is the sole therapeutic strategy. In this report, we present a case of GTS in a 20-year-old female following treatment for immature teratoma, alongside a review of the relevant literature aimed at enriching our insight into the clinical manifestations of GTS.","PeriodicalId":507440,"journal":{"name":"Frontiers in Oncology","volume":"35 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141649369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial: Multimodal treatment of recurrence and distant metastases of colorectal cancer 社论:大肠癌复发和远处转移的多模式治疗
Frontiers in Oncology Pub Date : 2024-07-11 DOI: 10.3389/fonc.2024.1455405
Andrea Balla, D. Corallino, Diego Coletta, P. Sileri, S. Di Saverio, S. Morales-Conde
{"title":"Editorial: Multimodal treatment of recurrence and distant metastases of colorectal cancer","authors":"Andrea Balla, D. Corallino, Diego Coletta, P. Sileri, S. Di Saverio, S. Morales-Conde","doi":"10.3389/fonc.2024.1455405","DOIUrl":"https://doi.org/10.3389/fonc.2024.1455405","url":null,"abstract":"","PeriodicalId":507440,"journal":{"name":"Frontiers in Oncology","volume":"134 41","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141656403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial: Video-assisted surgery in oncology 社论:肿瘤学中的视频辅助手术
Frontiers in Oncology Pub Date : 2024-07-10 DOI: 10.3389/fonc.2024.1420249
Jianrong Zhang, He Liu, Jinbo Chen, Zhiming Ma, Long Jiang
{"title":"Editorial: Video-assisted surgery in oncology","authors":"Jianrong Zhang, He Liu, Jinbo Chen, Zhiming Ma, Long Jiang","doi":"10.3389/fonc.2024.1420249","DOIUrl":"https://doi.org/10.3389/fonc.2024.1420249","url":null,"abstract":"","PeriodicalId":507440,"journal":{"name":"Frontiers in Oncology","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141661173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial: Advances in genetics and molecular diagnosis in colorectal, stomach, and pancreatic cancer vol II 社论:结直肠癌、胃癌和胰腺癌遗传学和分子诊断的进展》第二卷
Frontiers in Oncology Pub Date : 2024-07-10 DOI: 10.3389/fonc.2024.1448183
J. Soarez, Carlos Alberto Vaccaro, M. Dominguez-Valentin, W. Pavicic
{"title":"Editorial: Advances in genetics and molecular diagnosis in colorectal, stomach, and pancreatic cancer vol II","authors":"J. Soarez, Carlos Alberto Vaccaro, M. Dominguez-Valentin, W. Pavicic","doi":"10.3389/fonc.2024.1448183","DOIUrl":"https://doi.org/10.3389/fonc.2024.1448183","url":null,"abstract":"","PeriodicalId":507440,"journal":{"name":"Frontiers in Oncology","volume":"37 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141660481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial: Precision therapy and biomarkers in head and neck squamous cell carcinoma 社论:头颈部鳞状细胞癌的精准治疗和生物标志物
Frontiers in Oncology Pub Date : 2024-07-08 DOI: 10.3389/fonc.2024.1442630
Luis Abel Quiñones, Fujun Han, Ye Guo
{"title":"Editorial: Precision therapy and biomarkers in head and neck squamous cell carcinoma","authors":"Luis Abel Quiñones, Fujun Han, Ye Guo","doi":"10.3389/fonc.2024.1442630","DOIUrl":"https://doi.org/10.3389/fonc.2024.1442630","url":null,"abstract":"","PeriodicalId":507440,"journal":{"name":"Frontiers in Oncology","volume":"124 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141667688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial: The MACC1 network in cancer 社论:癌症中的 MACC1 网络
Frontiers in Oncology Pub Date : 2024-07-05 DOI: 10.3389/fonc.2023.1343812
W. Walther, Franziska Siegel, U. Stein
{"title":"Editorial: The MACC1 network in cancer","authors":"W. Walther, Franziska Siegel, U. Stein","doi":"10.3389/fonc.2023.1343812","DOIUrl":"https://doi.org/10.3389/fonc.2023.1343812","url":null,"abstract":"","PeriodicalId":507440,"journal":{"name":"Frontiers in Oncology","volume":" 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141676329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial: Sex differences in cancer incidence, mortality, and survival: methodological perspectives 社论:癌症发病率、死亡率和存活率的性别差异:方法论视角
Frontiers in Oncology Pub Date : 2024-07-05 DOI: 10.3389/fonc.2024.1441965
Syed Ahsan Raza, Wilson Luiz da Costa, A. Thrift
{"title":"Editorial: Sex differences in cancer incidence, mortality, and survival: methodological perspectives","authors":"Syed Ahsan Raza, Wilson Luiz da Costa, A. Thrift","doi":"10.3389/fonc.2024.1441965","DOIUrl":"https://doi.org/10.3389/fonc.2024.1441965","url":null,"abstract":"","PeriodicalId":507440,"journal":{"name":"Frontiers in Oncology","volume":" 34","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141675767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial: PET/CT and MRI in prostate cancer 社论:PET/CT 和 MRI 在前列腺癌中的应用
Frontiers in Oncology Pub Date : 2024-05-24 DOI: 10.3389/fonc.2024.1421542
Fabio Grizzi, Gianluigi Taverna
{"title":"Editorial: PET/CT and MRI in prostate cancer","authors":"Fabio Grizzi, Gianluigi Taverna","doi":"10.3389/fonc.2024.1421542","DOIUrl":"https://doi.org/10.3389/fonc.2024.1421542","url":null,"abstract":"","PeriodicalId":507440,"journal":{"name":"Frontiers in Oncology","volume":"85 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141101539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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