Jornal Brasileiro de Pneumologia最新文献

Intrapericardial fibrinolysis and video-assisted thoracoscopic surgery in managing severe pediatric Streptococcus pneumoniae purulent complications 心包内纤维蛋白溶解术和视频辅助胸腔镜手术治疗严重的小儿肺炎链球菌化脓性并发症

Jornal Brasileiro de Pneumologia Pub Date : 2024-07-26 DOI: 10.36416/1806-3756/e20240127

Jinghui Jiang1, Qianqian Du2, Jun Liang1, Kaihu Yao2

引用次数: 0

EBUS-TBNA in mediastinal staging of non-small cell lung cancer: comparison with pathological staging EBUS-TBNA 在非小细胞肺癌纵隔分期中的应用：与病理分期的比较

Jornal Brasileiro de Pneumologia Pub Date : 2024-07-23 DOI: 10.36416/1806-3756/e20230353

Sara Braga1, Rita Costa2, Adriana Magalhães3, Gabriela Fernandes3

{"title":"EBUS-TBNA in mediastinal staging of non-small cell lung cancer: comparison with pathological staging","authors":"Sara Braga1, Rita Costa2, Adriana Magalhães3, Gabriela Fernandes3","doi":"10.36416/1806-3756/e20230353","DOIUrl":"https://doi.org/10.36416/1806-3756/e20230353","url":null,"abstract":"Objective: Although EBUS-TBNA combined with EUS-FNA or EUS-B-FNA stands as the primary approach for mediastinal staging in lung cancer, guidelines recommend mediastinoscopy confirmation if a lymph node identified on chest CT or showing increased PET scan uptake yields negativity on these techniques. This study aimed to assess the staging precision of EBUS/EUS. Methods: We conducted a retrospective study comparing the clinical staging of non-small cell lung cancer patients undergoing EBUS/EUS with their post-surgery pathological staging. We analyzed the influence of histology, location, tumor size, and the time lapse between EBUS and surgery. Patients with N0/N1 staging on EBUS/EUS, undergoing surgery, and with at least one station approached in both procedures were selected. Post-surgery, patients were categorized into N0/N1 and N2 groups. Results: Among the included patients (n = 47), pathological upstaging to N2 occurred in 6 (12.8%). Of these, 4 (66.7%) had a single N2 station, and 2 (33.3%) had multiple N2 stations. The adenopathy most frequently associated with upstaging was station 7. None of the analyzed variables demonstrated a statistically significant difference in the occurrence of upstaging. PET scan indicated increased uptake in only one of these adenopathies, and only one was visualized on chest CT. Conclusions: Upstaging proved independent of the studied variables, and only 2 patients with negative EBUS/EUS would warrant referral for mediastinoscopy. Exploring other noninvasive methods with even greater sensitivity for detecting micrometastatic lymph node disease is crucial.","PeriodicalId":507373,"journal":{"name":"Jornal Brasileiro de Pneumologia","volume":"100 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141812201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pediatric obstructive sleep apnea: diagnosis and management 小儿阻塞性睡眠呼吸暂停：诊断和管理

Jornal Brasileiro de Pneumologia Pub Date : 2024-07-23 DOI: 10.36416/1806-3756/e20240203

Luiza Fernandes Xavier1, Paula Barros de Barros1, Sofia Prates da Cunha de Azevedo1, Leonardo Araujo Pinto2,3, Magali Santos Lumertz2,3

引用次数: 0

Talc slurry versus thoracoscopic talc insufflation for malignant pleural effusion: a systematic review and meta-analysis 滑石粉浆与胸腔镜滑石粉充气治疗恶性胸腔积液：系统回顾和荟萃分析

Jornal Brasileiro de Pneumologia Pub Date : 2024-07-23 DOI: 10.36416/1806-3756/e20240115

Anna Luíza Soares de Oliveira Rodrigues1, Maria Eduarda Cavalcanti Souza2, Francisco Cezar Aquino de Moraes3, David Paes de Lima4, Rafael Lucas Costa de Carvalho4

{"title":"Talc slurry versus thoracoscopic talc insufflation for malignant pleural effusion: a systematic review and meta-analysis","authors":"Anna Luíza Soares de Oliveira Rodrigues1, Maria Eduarda Cavalcanti Souza2, Francisco Cezar Aquino de Moraes3, David Paes de Lima4, Rafael Lucas Costa de Carvalho4","doi":"10.36416/1806-3756/e20240115","DOIUrl":"https://doi.org/10.36416/1806-3756/e20240115","url":null,"abstract":"Objective: Talc pleurodesis is a widely used treatment option for malignant pleural effusion (MPE). However, the optimal form of administration remains controversial. Thus, we performed a systematic review and meta-analysis to assess the effectiveness of talc slurry (TS) in comparison with thoracoscopic talc insufflation/poudrage (TTI) for MPE treatment. Methods: We searched PubMed, EMBASE, and Cochrane Library databases for studies that compared TS with TTI in patients with MPE. We used a random-effects model with a 95% CI to pool the data. Heterogeneity was assessed with I² statistics. Results: We included eight studies involving 1,163 patients, 584 of whom (50.21%) underwent TS. Pleurodesis failure rates were similar between the procedures (OR = 1.07; 95% CI: 0.56-2.06; p = 0.83; I² = 62%); and 68% of patients (95% CI: 0.31-1.47; p = 0.33; I² = 58%) had postoperative complications, which were lower in patients in the TS group than in the TTI group. In a subgroup analysis considering only randomized clinical trials, the failure rate was significantly lower in the TS treatment group (OR = 0.62; 95% CI: 0.42-0.90; p = 0.01; I² = 0%). Similarly, dyspnea was less common in the TS group (OR = 0.74; 95% CI: 0.41-1.34; p = 0.32; I² = 55%). Adverse effects were reported in 86 patients, and no significant difference was seen between the TS and TTI groups: empyema (OR = 1.43; 95% CI: 0.36-5.64; p = 0.86; I² = 0%), pain (OR = 1.22 (95% CI: 0.67-2.21; p = 0.51; I² = 38%), and pneumonia (OR = 1.15; 95% CI: 0.30-4.46; p = 0.86; I² = 27%). Conclusions: Our findings suggest that TS is an effective treatment for MPE, with no significant increase in adverse events. Results suggest equivalent efficacy and safety for both procedures.","PeriodicalId":507373,"journal":{"name":"Jornal Brasileiro de Pneumologia","volume":"126 33","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141811472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Using data from patient registries to answer important research questions 利用患者登记数据回答重要的研究问题

Jornal Brasileiro de Pneumologia Pub Date : 2024-07-16 DOI: 10.36416/1806-3756/e20240216

Samia Rached1,2, Cecilia M Patino1,3, Juliana Ferreira1,2

引用次数: 0

Calcifications in multiple lymph node chains 多条淋巴结链出现钙化

Jornal Brasileiro de Pneumologia Pub Date : 2024-07-16 DOI: 10.36416/1806-3756/e20240152

Edson Marchiori1, Bruno Hochhegger2, Gláucia Zanetti1

引用次数: 0

Assessing alternative treatment targets in patients with cystic fibrosis 评估囊性纤维化患者的替代治疗目标

Jornal Brasileiro de Pneumologia Pub Date : 2024-07-16 DOI: 10.36416/1806-3756/e20240218

Rodrigo Cavallazzi1, Marcia Pizzichini2

引用次数: 0

Respiratory syncytial virus infection in children during SARS-CoV-2 pandemic at a referral center in Rio de Janeiro, Brazil 巴西里约热内卢一家转诊中心在 SARS-CoV-2 大流行期间的儿童呼吸道合胞病毒感染情况

Jornal Brasileiro de Pneumologia Pub Date : 2024-07-09 DOI: 10.36416/1806-3756/e20240072

Giuliana Pucarelli Lebreiro1, Marianna Tavares Venceslau1, Maria Angélica Arpon Marandino Guimarães1, Thalita Fernandes Abreu2, Yarina Rangel2, Ana Cristina Cisne Frota2, Cristina Barroso Hofer1

{"title":"Respiratory syncytial virus infection in children during SARS-CoV-2 pandemic at a referral center in Rio de Janeiro, Brazil","authors":"Giuliana Pucarelli Lebreiro1, Marianna Tavares Venceslau1, Maria Angélica Arpon Marandino Guimarães1, Thalita Fernandes Abreu2, Yarina Rangel2, Ana Cristina Cisne Frota2, Cristina Barroso Hofer1","doi":"10.36416/1806-3756/e20240072","DOIUrl":"https://doi.org/10.36416/1806-3756/e20240072","url":null,"abstract":"Objective: In order to study the scenario of respiratory infections in pediatrics after the emergence of SARS-CoV-2 in Brazil, this study aimed to compare characteristics of children admitted for SARS or upper airway infection caused by either RSV or SARS-CoV-2. Methods: This was a cross-sectional study involving children up to 48 months of age admitted to a tertiary pediatric hospital with a diagnosis of SARS or upper airway infection between April of 2020 and April of 2021. Respiratory secretion samples were collected 2-5 days after hospitalization, and antigen/PCR tests for viral etiologies were performed. In this analysis, patients with laboratorial diagnosis of SARS-CoV-2 and/or RSV were selected, and their clinical and epidemiological characteristics were compared using logistic regression. Results: Our sample initially comprised 369 participants. SARS-CoV-2 and RSV infections were confirmed in 55 (15%) and 59 children (16%), respectively. Mean age was 12 months (0-48 months), and 47 were female. The following characteristics were significantly more frequent in patients with RSV when compared with those with COVID-19: younger age (OR = 0.94; 95% CI: 0.90-0.98); lower frequency of fever (OR = 0.18; 95% CI: 0.05-0.66); and more frequent upper airway symptoms: cough (OR = 7.36; 95% CI: 1.04-52.25); and tachypnea (OR = 6.06; 95% CI: 1.31-28.0). Conclusions: Children with RSV-related SARS were younger, had lower frequency of fever at admission, but had a higher frequency of signs of upper airway infection and lower systemic inflammation when compared with children hospitalized for COVID-19 during the first year of the pandemic.","PeriodicalId":507373,"journal":{"name":"Jornal Brasileiro de Pneumologia","volume":"27 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141663543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mesothelioma diagnosis—still a challenge 间皮瘤诊断--仍是一项挑战

Jornal Brasileiro de Pneumologia Pub Date : 2024-05-10 DOI: 10.36416/1806-3756/e20240118

Ubiratan de Paula Santos1

引用次数: 0

Atypical bacterial respiratory infections in children 儿童非典型细菌性呼吸道感染

Jornal Brasileiro de Pneumologia Pub Date : 2024-05-10 DOI: 10.36416/1806-3756/e20240126

Paula Barros de Barros1, Luiza Fernandes Xavier1, Eduardo da Costa Herter1, Maria Fernanda Gonçalves Meirelles Fernandes1, Isabel Cristina Schütz Ferreira2, Leonardo Araujo Pinto2

引用次数: 0