IJU Case Reports最新文献

Effect of rechallenge nivolumab in a hemodialysis patient with multiple metastases from a rapidly progressed T1a renal clear cell carcinoma: An autopsy case 对一名患有快速进展的 T1a 肾透明细胞癌多发转移灶的血液透析患者重新挑战 nivolumab 的效果：一个尸检病例

IJU Case Reports Pub Date : 2024-02-14 DOI: 10.1002/iju5.12699

Kazushi Hanawa, N. Sawada, Yuka Yokota, Junki Aikawa, Yuko Otake, Koki Sugimura, H. Shimura, Takanori Mochizuki, S. Kira, Takahiko Mitsui

{"title":"Effect of rechallenge nivolumab in a hemodialysis patient with multiple metastases from a rapidly progressed T1a renal clear cell carcinoma: An autopsy case","authors":"Kazushi Hanawa, N. Sawada, Yuka Yokota, Junki Aikawa, Yuko Otake, Koki Sugimura, H. Shimura, Takanori Mochizuki, S. Kira, Takahiko Mitsui","doi":"10.1002/iju5.12699","DOIUrl":"https://doi.org/10.1002/iju5.12699","url":null,"abstract":"Distant metastasis of T1a renal cell carcinoma is rare and whether metastasis is more probable in patients undergoing hemodialysis remains unclear. We report the autopsy case of a patient undergoing hemodialysis with multiple metastases that rapidly progressed from T1a renal cell carcinoma treated with multimodal therapy including nivolumab.A 70‐year‐old male who underwent hemodialysis was diagnosed with clear cell carcinoma (pT1a, G2) after nephrectomy. Six months post‐surgery, bone and lung metastases appeared and treated with radiotherapy and pazopanib, respectively. Nivolumab was administered as second‐ and fourth‐line treatments for lung metastases. The patient died approximately 60 months after initial diagnosis; however, nivolumab controlled disease progression for 24 months. An autopsy revealed the lung's occupation with clear cell carcinoma tumor tissue.Nivolumab has potential to control lung metastasis progression. Additionally, rechallenge is possible in patients with renal cell carcinoma undergoing hemodialysis.","PeriodicalId":507273,"journal":{"name":"IJU Case Reports","volume":"34 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139779568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A diagnostically challenging case of inflammatory myofibroblastic tumor primary to the peritoneum 腹膜原发性炎性肌纤维母细胞瘤的诊断难题病例

IJU Case Reports Pub Date : 2024-02-14 DOI: 10.1002/iju5.12701

Jurii Karibe, J. Teranishi, Takashi Kawahara, Takeaki Noguchi, T. Takeshima, K. Osaka, Eita Kumagai, T. Sawazumi, Satoshi Fujii, Hiroji Uemura

引用次数: 0

A seed link connector protruding into the bladder formed a bladder stone 突出到膀胱中的种子链接接头形成了膀胱结石

IJU Case Reports Pub Date : 2024-02-09 DOI: 10.1002/iju5.12704

Shuhei Aoyama, K. Izumi, Tomoyuki Makino, R. Naito, S. Kadomoto, H. Iwamoto, H. Yaegashi, Shohei Kawaguchi, K. Shigehara, T. Nohara, Atsushi Mizokami

引用次数: 0

Three cases of sperm immobility for intracytoplasmic sperm injection using testicular sperm 三例使用睾丸精子进行卵胞浆内单精子注射的精子不活动病例

IJU Case Reports Pub Date : 2024-02-09 DOI: 10.1002/iju5.12702

Noboru Mimura, T. Takeshima, Shun Aoki, Tomoki Saito, Jurii Karibe, Y. Yumura

{"title":"Three cases of sperm immobility for intracytoplasmic sperm injection using testicular sperm","authors":"Noboru Mimura, T. Takeshima, Shun Aoki, Tomoki Saito, Jurii Karibe, Y. Yumura","doi":"10.1002/iju5.12702","DOIUrl":"https://doi.org/10.1002/iju5.12702","url":null,"abstract":"Sperm immobility is a condition in which sperm are viable but not motile. We reported three patients with sperm immobility, who underwent testicular sperm extraction‐intracytoplasmic sperm injection.In case 1, a 32‐year‐old patient with sperm immobility had previously undergone intracytoplasmic sperm injection with ejaculated sperm; however, pregnancy was unsuccessful. testicular sperm extraction‐intracytoplasmic sperm injection was performed at our clinic, and pregnancy was achieved. In case 2, a 23‐year‐old patient with clinical varicocele whose semen analysis revealed sperm immobility underwent varicocelectomy, without improvement. Using the hypo‐osmotic swelling test technique, testicular sperm extraction‐intracytoplasmic sperm injection was performed; however, pregnancy was not achieved. In case 3, a 44‐year‐old patient with sperm immobility underwent testicular sperm extraction, and motile sperm were retrieved. testicular sperm extraction‐intracytoplasmic sperm injection using these sperm resulted in pregnancy.Although testicular sperm extraction‐intracytoplasmic sperm injection is not considered a solution in patients with sperm immobility, pregnancies were achieved. testicular sperm extraction‐intracytoplasmic sperm injection may be successful in some cases in which ejaculated sperm intracytoplasmic sperm injection is unsuitable.","PeriodicalId":507273,"journal":{"name":"IJU Case Reports","volume":" 27","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139789361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful treatment with low‐dose oral steroids for contracted bladder after intravesical instillation of Bacillus Calmette–Guérin 用小剂量口服类固醇成功治疗膀胱内注射卡介苗后的膀胱收缩症

IJU Case Reports Pub Date : 2024-02-02 DOI: 10.1002/iju5.12700

Akinobu Katami, Takamitsu Inoue, Hiromichi Sakurai, M. Onozawa, Shin‐ichi Hisasue, Koji Kawai, Junichi Miyazaki

引用次数: 0