Nepal Medical College Journal最新文献_第3页

Evaluation of Medical Management of Phimosis in Pediatric Patients: A Descriptive Cross Sectional Study 儿科患者包皮过长的医学治疗评估：描述性横断面研究

Nepal Medical College Journal Pub Date : 2024-04-02 DOI: 10.3126/nmcj.v26i1.63886

J. Bajracharya, Bineet Thapa, Kaushal Oli, Deepika Lamichhane, Rit Shrestha

{"title":"Evaluation of Medical Management of Phimosis in Pediatric Patients: A Descriptive Cross Sectional Study","authors":"J. Bajracharya, Bineet Thapa, Kaushal Oli, Deepika Lamichhane, Rit Shrestha","doi":"10.3126/nmcj.v26i1.63886","DOIUrl":"https://doi.org/10.3126/nmcj.v26i1.63886","url":null,"abstract":"Phimosis is considered virtually universal in newborn males. Circumcision is mostly done for unresolved phimosis. There is a stream of evidence that suggests steroid cream application is effective in these children prior to any surgical decision. A cross-sectional descriptive study from October 2021 to November 2022, was designed to include all cases of phimosis in male children up to 15 years of age. Caregivers of the patients were counseled and advised for management with hydrocortisone 1.0% ointment twice a daily and follow up in 2 weeks. The resolution rates were noted in 2 weeks and 4 weeks and unresolved children were counseled for either continuation of medical management or circumcision. Electronic registry was used to enroll all the cases and note the outcomes. A total of 146 boys were evaluated. Median age of presentation was 4 years, 113 children (77.4%) were successfully treated with medical therapy and only 33 children (22.6%) had failed medical therapy requiring circumcision. A total of 66 children (58.4%) required only 1 followup for resolution of phimosis. By contrast, 47 children (41.6%) required more than 1 follow-up for resolution. Topical steroid in treatment of phimosis is a very safe, effective, inexpensive and easy approach that attenuates the need for surgical intervention. The response rate is very high and adverse effects are minimal. In the developing world, medical therapy can thus be more feasible of an option as compared to surgery.","PeriodicalId":506882,"journal":{"name":"Nepal Medical College Journal","volume":"256 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140751432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hematological and Biochemical Profiles of Patients with Dengue Virus Infection in Lalitpur, Nepal 尼泊尔拉利特普尔登革热病毒感染患者的血液学和生物化学特征

Nepal Medical College Journal Pub Date : 2024-04-02 DOI: 10.3126/nmcj.v26i1.63877

Indira Rai, Subash Paudel, Santosh Shrestha, Debbie Manandhar, Shiba Kumar Rai

{"title":"Hematological and Biochemical Profiles of Patients with Dengue Virus Infection in Lalitpur, Nepal","authors":"Indira Rai, Subash Paudel, Santosh Shrestha, Debbie Manandhar, Shiba Kumar Rai","doi":"10.3126/nmcj.v26i1.63877","DOIUrl":"https://doi.org/10.3126/nmcj.v26i1.63877","url":null,"abstract":"Dengue viral infection is a disease transmitted by mosquitoes of the Aedes genus, and it arises as a result of being bitten by mosquitoes that are carrying the virus. This infection induces a wide range of changes in the body’s immune system. Thus serological evaluation together with hematological and biochemical parameters in cases of dengue viral infection make an accurate clinical diagnosis. The main objective of this study was to study the serological, hematological, and biochemical parameters among patients infected with Dengue virus. A total of 102 blood samples were collected at Asrik Diagnostic Lab, Lalitpur during the period of August to October 2022. Samples were analyzed by following methods: hematological tests were done by coulter counter, Biochemical tests were done by fully automated analyzer and serological tests were done by ELISA. Of the 102 blood samples NS1 antigen was detected in 62 (60.9%) whereas anti-dengue IgM antibody was detected in 10 (9.8%). Leukopenia and thrombocytopenia were present in 33 (53.1%) and 32 (51.6%) of the 62 NS1 positive samples, respectively. Of the 62 cases, only 16 samples were tested for the alanine aminotransferase (ALT) and aspartate aminotransferase (AST). Out of 16 samples, ALT and AST level were significantly higher in 11 (68.8%) and 14 (87.5%) positive cases, respectively. The statistical analysis showed that there was no significant association between NS1 and IgM. It can be concluded that the investigation of leukocytes, thrombocytes, ALT, and AST helps to diagnose the dengue efficiently.","PeriodicalId":506882,"journal":{"name":"Nepal Medical College Journal","volume":"15 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140753992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outcome of Real Time Self-visualization of Rigid Cystoscopy Procedure on Procedural Pain in Male Patients 刚性膀胱镜检查过程中的实时自我可视化对男性患者手术疼痛的影响

Nepal Medical College Journal Pub Date : 2024-04-02 DOI: 10.3126/nmcj.v26i1.63873

Mohan Khadka, K. K. Bhomi, Bineet Thapa, Anup Gautam, Mansi Ghimire, Adwitiya Jha

{"title":"Outcome of Real Time Self-visualization of Rigid Cystoscopy Procedure on Procedural Pain in Male Patients","authors":"Mohan Khadka, K. K. Bhomi, Bineet Thapa, Anup Gautam, Mansi Ghimire, Adwitiya Jha","doi":"10.3126/nmcj.v26i1.63873","DOIUrl":"https://doi.org/10.3126/nmcj.v26i1.63873","url":null,"abstract":"In patients undergoing fixed orthodontic therapy, favorable conditions for plaque stagnation as well as difficulty in performing usual oral hygiene measures have been associated with poorer periodontal health among orthodontic patients. So this study aims to assess the effect of the duration of fixed orthodontic treatment on presence of gingival enlargement in adolescents and young adults. This cross sectional descriptive study was conducted in the dental hospital of Nepal Medical College Teaching Hospital. Patients under fixed orthodontic therapy for at least 3 months were examined for the presence of gingival enlargement (GE). Demographic variables and the details of duration of the fixed orthodontic therapy was recorded along with presence of gingival enlargement and its grading. The oral hygiene habits like frequency of brushing, use of interdental cleaning aids were recorded along with plaque index. Gingival enlargement was present in 204 (63.7%) out of total 320 patients taken, among which 124 patients (38.8%) had gingival enlargement of score 1 and 80 (25.0%) patients had gingival enlargement of score 2. Gingival enlargement was observed in 101 (73.2%) in 20-30 years old patients which was more prevalent in this age group. Oral hygiene habits like frequency of brushing and use of interdental aids also seem to affect the occurrence of gingival enlargement in patients. Among those who were undergoing orthodontic therapy for more than 2 years, 48 (82.8%) had presence of gingival enlargement. Mean of plaque index was seen to be statistically associated with presence of gingival enlargement. Thus, this study showed that the duration of orthodontic treatment duration significantly influenced the occurrence of GE. Therefore, oral hygiene instructions and motivations should be reinforced for patients undergoing orthodontic treatment.","PeriodicalId":506882,"journal":{"name":"Nepal Medical College Journal","volume":"28 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140754128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Drug Induced Rowell’s Syndrome: A Rare Presentation 药物诱发的罗威综合征：一种罕见的表现

Nepal Medical College Journal Pub Date : 2024-04-02 DOI: 10.3126/nmcj.v26i1.63893

Arnija Rana, D. P. Thapa, Shristi Shrestha, Prabin Adhikari, Asim Shrestha

引用次数: 0

Comparison of Post-operative Pain with and without Infiltration of Bupivacaine Hydrochloride in Tonsillectomy 扁桃体切除术中渗入和未渗入盐酸布比卡因的术后疼痛比较

Nepal Medical College Journal Pub Date : 2024-04-02 DOI: 10.3126/nmcj.v26i1.63874

Alina Acharya, Meera Bista

{"title":"Comparison of Post-operative Pain with and without Infiltration of Bupivacaine Hydrochloride in Tonsillectomy","authors":"Alina Acharya, Meera Bista","doi":"10.3126/nmcj.v26i1.63874","DOIUrl":"https://doi.org/10.3126/nmcj.v26i1.63874","url":null,"abstract":"Tonsillectomy is the complete removal of a tonsil from its bed and is one of the most common procedures in Otorhinolaryngology. The intensity of post-operative pain is severe enough to cause dysphagia which subsequently leads to infection of the fossa and other complications. Several studies on pain management have been conducted but not a single standard protocol currently exist. This study aims to evaluate the intensity of post tonsillectomy pain and to assess the efficacy of infiltration of Bupivacaine on the tonsillar fossa following tonsillectomy. A comparative study was conducted at Kathmandu Medical College, ENT-HNS department for a period of 18 months (January 2018 to June 2019). Ninety three patients were included. 2.5 ml of 0.5% Bupivacaine was infiltrated in right tonsillar fossa after tonsillectomy in all patients. The lateralization and intensity of pain at various post-operative period was assessed using visual analogue scale. The requirement of extra analgesics at various post-operative period was recorded. The pain score on the Bupivacaine side on the first and second post-operative day was decreased as compared to the other side. The pain score on the fourth hour and third post-operative day on Bupivacaine side was more than that of the other side. Infiltration of Bupivacaine over the tonsillar fossa has provided a good result with a significant reduction of pain in first post-operative day and in early post-operative period. However, other multi-centered and double blinded study is requires to provide better results.","PeriodicalId":506882,"journal":{"name":"Nepal Medical College Journal","volume":"98 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140751656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of Health Education Intervention on Knowledge Regarding Prevention of Cervical Cancer among Women in a Selected Community of Kathmandu, Nepal 健康教育干预对尼泊尔加德满都部分社区妇女预防宫颈癌知识的影响

Nepal Medical College Journal Pub Date : 2024-04-02 DOI: 10.3126/nmcj.v26i1.63891

B. Gorkhali, M. Amatya

{"title":"Effectiveness of Health Education Intervention on Knowledge Regarding Prevention of Cervical Cancer among Women in a Selected Community of Kathmandu, Nepal","authors":"B. Gorkhali, M. Amatya","doi":"10.3126/nmcj.v26i1.63891","DOIUrl":"https://doi.org/10.3126/nmcj.v26i1.63891","url":null,"abstract":"Cervical cancer is considered a cancer that is preventable by means of vaccination against human papilloma virus (HPV) and early detection by screening. Its incidence is decreasing in developed countries but not in developing countries, including Nepal. Disease ignorance and low awareness about available preventive health services are the main causes for cervical cancer still being a leading cause of death by cancer. We evaluated the effectiveness of a health educational intervention in improving women’s knowledge about cervical cancer and its prevention in a semi-urban community of Kathmandu. Health education was provided in an interactive lecture for women of reproductive age in various wards of Shankarapur Municipality, Kathmandu. Its effectiveness was assessed by comparing the level of knowledge before and four weeks after the intervention, by interviewing participants based on a questionnaire consisting of 48 questions. The study was completed in 126 women (mean age 33.5 years). The mean pre-test and post-test correct scores were 10.2 and 42.13 respectively (p <0.001). Initially, 96.8% had poor knowledge (score <60.0% of total); post-intervention, 87.3% had good knowledge (score ≥80.0%, p <0.001). Knowledge before intervention was especially poor among older age, less educated, housewives or doing small business, and married women (p <0.001). Knowledge of cervical cancer and its prevention is poor among community women. A health education is very effective in improving women’s knowledge and should be implemented as a policy to achieve the goal of eliminating cervical cancer as a public health issue.","PeriodicalId":506882,"journal":{"name":"Nepal Medical College Journal","volume":"129 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140755172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bladder stone in pregnancy: a rare encounter 妊娠期膀胱结石：罕见病例

Nepal Medical College Journal Pub Date : 2023-12-22 DOI: 10.3126/nmcj.v25i4.60932

Maryada Malla, Sandesh Poudel

引用次数: 0

Knowledge, attitude and practice of pregnant women attending a health facility regarding the COVID -19 pandemic: pre and post-vaccination 到医疗机构就诊的孕妇对 COVID-19 大流行的了解、态度和做法：接种前和接种后

Nepal Medical College Journal Pub Date : 2023-12-22 DOI: 10.3126/nmcj.v25i4.60925

Anshumala Joshi, Nishchal Dhakal

引用次数: 0

Hospital admissions and the financial cost incurred by the elderly patients at a tertiary care centre in Gokarneshwor Municipality, Kathmandu, Nepal 尼泊尔加德满都 Gokarneshwor 市一家三级医疗中心老年患者的入院情况和经济成本

Nepal Medical College Journal Pub Date : 2023-12-22 DOI: 10.3126/nmcj.v25i4.60874

Niraj Shrestha, Leepy Paudel, Prakriti Baral

{"title":"Hospital admissions and the financial cost incurred by the elderly patients at a tertiary care centre in Gokarneshwor Municipality, Kathmandu, Nepal","authors":"Niraj Shrestha, Leepy Paudel, Prakriti Baral","doi":"10.3126/nmcj.v25i4.60874","DOIUrl":"https://doi.org/10.3126/nmcj.v25i4.60874","url":null,"abstract":"Population ageing is a global phenomenon and proportion of elderly people is also increasing in Nepal. However, the increased burden of chronic disease as a result of population ageing, along with medical cost incurred during hospital stay is yet to be explored in Nepal. With the aim of studying these, data of 527 patients 70 years of age and above admitted to Nepal Medical College Teaching hospital, the largest tertiary care center in Gokarneshwor Municipality, was collected from November 2021 to November 2022 and analyzed. Seventy-four percent of the patients were of 70-80 years of age and male: female ratio was almost equal to 1:1. The most common cause of admission was respiratory problems. The cost was not more than Nepali rupees 19,200 for 82% of the patients and the duration of stay was less than 6 days for 75% of the patients. No significant association was found between duration of hospital stay and the age group or the gender. Similarly, no significant association was found between the medical cost incurred during hospital stay and the age group. However, association was found between the hospital cost and gender with males more likely to have higher cost.","PeriodicalId":506882,"journal":{"name":"Nepal Medical College Journal","volume":"123 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139163955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outcome of laparoscopic vs open appendectomy in the management of acute appendicitis 腹腔镜阑尾切除术与开腹阑尾切除术治疗急性阑尾炎的效果对比

Nepal Medical College Journal Pub Date : 2023-12-22 DOI: 10.3126/nmcj.v25i4.60922

Y. Limbu, S. Regmee, Spandan Darshan Adhikari, Bidur Prasad Acharya, R. Ghimire

{"title":"Outcome of laparoscopic vs open appendectomy in the management of acute appendicitis","authors":"Y. Limbu, S. Regmee, Spandan Darshan Adhikari, Bidur Prasad Acharya, R. Ghimire","doi":"10.3126/nmcj.v25i4.60922","DOIUrl":"https://doi.org/10.3126/nmcj.v25i4.60922","url":null,"abstract":"The worldwide trend of appendectomy is shifting from conventional open to the laparoscopic technique. The study’s objective was to compare laparoscopic and open appendectomy in terms of various operative and postoperative parameters to find the best operative technique. A prospective comparative study was conducted on 142 patients undergoing laparoscopic (n=43) or open appendectomy (n=99) from 1st February 2022 to 30th January 2023 under the Department of Surgery of Kathmandu Medical College Teaching Hospital (KMCTH). In five patients, laparoscopic appendectomy was later converted to open and excluded from the study. The mean operating time for the open appendectomy group was 44.1±13.1 minutes while for the laparoscopic appendectomy group, it was 48.4±14.0 minutes (p=0.047). Visual analogue score taken on 1st, 7th and 30th post-operative day for open and laparoscopic appendectomy were 4.0±2.2 vs 3.6±1.9 (p=0.160); 1.4±1.3 vs 0.6±0.9 (p<0.001) and 0.2±0.5 vs 0.02±0.15 (p=0.107) respectively. The total days of postoperative hospital stay were 1.57±0.96 for open appendectomy and 1.58±1.07 for laparoscopic appendectomy (p=0.843). However, laparoscopic appendectomy group had an earlier return to normal activity (7.30±1.15 days) when compared to the open appendectomy group (8.05±2.42 days) (p=0.023). The laparoscopic appendectomy group also had fewer postoperative complications than the open appendectomy group (18.6% vs 24.2%) (p=0.411). Thus, laparoscopy is a safe and effective method of removal of appendix for acute appendicitis.","PeriodicalId":506882,"journal":{"name":"Nepal Medical College Journal","volume":"179 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139165686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0