Veterinary World最新文献

{"title":"In vivo mosquito repellency effect of citronella (Cymbopogon nardus (L.) Rendle) essential oil bath bomb formulation in dogs","authors":"Suwit Uopasai, Ketmanee Senaphan, G. Borlace, Eakachai Thongkham, J. Aiemsaard","doi":"10.14202/vetworld.2024.1538-1544","DOIUrl":"https://doi.org/10.14202/vetworld.2024.1538-1544","url":null,"abstract":"Background and Aim: Mosquitoes carry numerous diseases of medical and veterinary significance. While citronella essential oil is safe as a mosquito repellent, extensive research does not document its ability to deter mosquitoes from animals. This study assessed the citronella essential oil bath bomb’s ability to repel Culex quinquefasciatus mosquitoes in dogs. \u0000\u0000Materials and Methods: Citronella essential oil’s chemical composition was analyzed using gas chromatography-mass spectrometry (GC-MS). Through freeze-thaw testing, a bath bomb formulation containing 6% w/w citronella essential oil was assessed for its physical and chemical stability. Thirty-two healthy client-owned mixed-breed dogs were employed to test the mosquito-repellency effects of citronella essential oil (treatment group) and olive oil (control group) bath bomb formulations. Bath bombs were tested for irritation effects on animal skin for 15-day post-application. \u0000\u0000Results: Thirty-six compounds were identified through GC-MS, with citronellal (23.38%), δ-cadinene (12.25%), and geraniol (9.09%) being the most prevalent constituents. The bath bomb maintained its original physical properties after undergoing six freeze-thawing cycles and retained over 90% of its citronella essential oil. About 100%, 69.28%, and 65.58% mosquito repellency were displayed by the citronella essential oil bath bomb at 3 h, 6 h, and 8 h, respectively. None of the test animals exhibited skin irritation during the study. \u0000\u0000Conclusion: The citronella bath bomb effectively repelled C. quinquefasciatus in dogs without irritating their skin. The formulation’s physical and chemical stability is demonstrated by the results of freeze-thaw stability testing. Further studies should be conducted to evaluate the repelling activity against other mosquito species. \u0000\u0000Keywords: bath bomb formulation, Culex quinquefasciatus, Cymbopogon nardus, mosquito repellent, vector control.","PeriodicalId":506834,"journal":{"name":"Veterinary World","volume":"237 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141711543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of neem leaf extract (Azadirachta indica) in reducing the degree of parasitemia and apoptosis in C57BL mice with cerebral malaria","authors":"Z. Rahmah, Kautsar Citra Nirmala, Achmad Nashichuddin, Riskiyana Riskiyana, Alvi Milliana, Nurfianti Indriana, L. Astari, Prida Ayudianti, Munawar Kholil","doi":"10.14202/vetworld.2024.1497-1503","DOIUrl":"https://doi.org/10.14202/vetworld.2024.1497-1503","url":null,"abstract":"Background and Aim: Brain malaria, which results from Plasmodium falciparum infection, is responsible for substantial fatalities and health issues. These processes, including cytoadherence, rosetting, and sequestration, induce an immune response, hypoxia, brain microvascular obstruction, disruption of the blood-brain barrier, and cell death. Parasitemia level can reveal the presence of infection and its association with apoptosis-related genes. Neem (Azadirachta indica) leaves with antimalarial properties could replace ineffective Indonesian malaria medications. This study was designed to evaluate the impact of neem leaf extract on cerebral malaria-induced parasitemia and neuron cell apoptosis in mice through an in vivo approach. \u0000\u0000Materials and Methods: 13–16 weeks old C57BL mice received infection by Plasmodium berghei strain ANKA. Parasitemia was estimated daily from the mice’s tail blood. 8 mg, 12 mg, and 16 mg of a 96% ethanolic neem leaf extract were orally given for 6 days. Healthy, positive, and negative controls were included for treatment comparisons. On the 7th day, brain tissue was analyzed for (p > 0.05) gene expression. Through immunohistochemistry, both cell apoptosis in neurons expressing caspase-3 within a brain sample and the degree of parasitemia in a blood smear were assessed. The Pearson correlation test and one-way analysis of variance were employed to analyze the data. \u0000\u0000Results: Neem leaf extract reduces parasitemia and neuron cell apoptosis at multiple dosages (p < 0.000). Apoptosis in brain neurons and parasitemia show a strong positive correlation (r = +0.939). Neem leaf extract at doses of 12 and 16 mg was the most effective in reducing parasitemia levels and causing cell death. \u0000\u0000Conclusion: Neem leaf therapy significantly reduced the degree of parasitemia and cell apoptosis in C57BL mice compared with the control group without treatment (p = 0.05). This shows that neem leaves have the potential to be a candidate drug for malaria. \u0000\u0000Keywords: apoptosis, Azadirachta indica, cerebral malaria, neem leaves, parasitemia.","PeriodicalId":506834,"journal":{"name":"Veterinary World","volume":"2016 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141706749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation and characterization of porcine parvovirus in Vietnam","authors":"T. T. H. Trinh, V. T. Do, V. K. Do, H. Vu-Khac","doi":"10.14202/vetworld.2024.1530-1537","DOIUrl":"https://doi.org/10.14202/vetworld.2024.1530-1537","url":null,"abstract":"Background and Aim: No study has successfully isolated parvovirus in Vietnam. This study aimed to isolate and characterize parvovirus strains indigenous in Vietnam for vaccine development against porcine parvovirus (PPV). \u0000\u0000Materials and Methods: We collected serum and stillbirth samples from six provinces in Vietnam, and PPV-positive samples were identified using a polymerase chain reaction. Parvovirus isolation was attempted using the PK-15 cells maintained in a minimum essential medium supplemented with 5% fetal bovine serum and 1% antibiotics (Penicillin-streptomycin). The cells were incubated at 37°C with 5% CO2. Virulence experiments were conducted on white primiparous sows to evaluate the virulence of the PPV strain through hemagglutination inhibition (HI) titers and fetus lesions. \u0000\u0000Results: We analyzed 360 serum and 32 stillbirth (liver and lungs) samples, revealing that 32/392 (8.2% ) of them were PPV-positive, all belonging to PPV1. Thirty-two PPV-positive samples were successfully isolated, with 100% identity as VP2 sequences. The phylogenetic tree revealed a close relationship with the Kresse strain (isolated from Canada in 1996) and the PPV1-0225-L-SD strain (isolated from China in 2022). Two PPV isolates (VC5 from Dongnai and TX7 from Thanhhoa) that exhibited high 50% tissue culture infectious dose titers were selected for the virulence experiment. On day 21, after injection, the HI antibody titers ranged from 10log2 to 12log2. On day 90, 71%–80% of fetuses were mummified. \u0000\u0000Conclusion: This study showed that the PPV infection rate in Vietnam was 8.2%. Thirty-two isolates belonged to PPV1. Two PPV strains, VC5 and TX7, were determined to be highly virulent by the results of HI titers after injection into gilts. VC5 and TX7 were determined to be good candidates for further research on PPV vaccines. \u0000\u0000Keywords: isolation, phylogenetic tree, porcine parvovirus, sow, virulence.","PeriodicalId":506834,"journal":{"name":"Veterinary World","volume":"2007 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141707179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of parity, season of birth, and sex on within-litter variation and pre-weaning performance of F1 Large White × Landrace pigs","authors":"Nqobile Lungile Buthelezi, B. Mtileni, K. Nephawe, Mamokoma Cathrine Modiba, Hezekiel Mpedi, P. Idowu, T. J. Mpofu","doi":"10.14202/vetworld.2024.1459-1468","DOIUrl":"https://doi.org/10.14202/vetworld.2024.1459-1468","url":null,"abstract":"Background and Aim: A piglet’s pre-weaning performance significantly influences both animal welfare and profitability in pig production. Understanding piglet pre-weaning performance influencing factors is key to enhancing animal welfare, reducing losses, and boosting profitability. The study aimed to evaluate the impact of parity, season of birth, and sex on within-litter variation and pre-weaning performance of F1 Large White × Landrace pigs. \u0000\u0000Materials and Methods: Information regarding total litter size, number of born alive, number of stillbirths, piglet weight at birth, mortality, and count of weaned F1 Large White × Landrace piglets was acquired from the farm database (April 2022–February 2023). 2602 females and 2882 males, a total of 5484 piglets were utilized, with records from 360 sows. The coefficient of variation (CV) of birth weights among piglets within a litter was calculated. The general linear model analysis in MiniTab 17 was used to evaluate the data, with Fisher’s least significant difference test (p < 0.05) used for mean separation and Pearson’s moment correlation coefficient calculated to assess relationships between survival rates, mortality rates, litter size, birth weight, and birth weight CV. \u0000\u0000Results: Parity had a statistically significant impact on litter size, birth weight, and survival rate (p < 0.05). The sow’s parity did not significantly (p > 0.05) impact the number of piglets born alive or weaned. Multiparous sows had a significantly larger litter size (p < 0.05) than primiparous sows at birth. The litter weights for parities 2, 4, and 5 did not significantly differ (p > 0.05), with averages of 20.95, 20.74, and 20.03 kg, respectively. About 91.29% was the highest survival rate recorded in parity 2 (p < 0.05). The 1st week of life recorded an 8.02% mortality rate. The mortality rate in parity 3–5 group was significantly (p < 0.05) higher (11.90%) in week 1 than in the other groups (parity 1: 6.79%, parity 2: 5.74%, parity 3–5: 8.54 and 9.21%). The litter sizes in autumn (17.34) and spring (17.72) were significantly larger (p < 0.05) than those in summer (16.47) and winter (16.83). In autumn and spring, the survival rate (83.15 and 85.84%, respectively) was significantly lower (p < 0.05) compared to summer (88.40%) and winter (89.07%). In all seasons, the litter weights did not significantly differ (p > 0.05). The birth weight CV was significantly (p < 0.05) lower during summer (20.11%) than during spring (22.43%), autumn (23.71%), and winter (21.69%). The season of birth had no significant effect (p > 0.05) on the number of live piglets. Males (1.34 kg) were heavier (p < 0.05) than females (1.30 kg) at birth. Notably, the birth weight CV was similar between males (22.43%) and females (22.52%). Litter size was positively correlated with average litter weight (rp = 0.576, p < 0.001), birth weight CV (rp = 0.244, p < 0.001), and mortality rate (rp = 0.378, p < 0.001). An insignificant relationship was observed betwe","PeriodicalId":506834,"journal":{"name":"Veterinary World","volume":"2016 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141707150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of a probiotic mixture with lactic acid activity on productive and allometric indicators in broiler chickens","authors":"Sandra Paola Rodríguez González, Luis Miguel Borras Sandoval, Torres Vidales Giovanny","doi":"10.14202/vetworld.2024.1490-1496","DOIUrl":"https://doi.org/10.14202/vetworld.2024.1490-1496","url":null,"abstract":"Background and Aim: The feeding and sanitary conditions significantly influence the productivity of farm animals. This study aimed to assess the impact of a lactic acid-producing microbial additive on broiler chicken productivity. \u0000\u0000Materials and Methods: A 42-day experimental period utilized 120 1-day-old Cobb 500 chicks with an average weight of 46 g. In groups of 30 each, the chicks were randomly assigned to four experimental designs. The following treatments were assessed: T1 without intervention (control), T2 with bacitracin at a concentration of 0.5 g/L, T3 with a 5% probiotic mixture (PM), and T4 with a 7.5% PM. The birds were fed the commercial balanced feed without anticoccidials daily, while vaccines were administered according to the recommended biosecurity plan by the commercial house. Drinking water was treated with PM containing lactobacilli, yeasts, and short-chain organic acids. \u0000\u0000Results: In T4, a 7.5% PM resulted in a final weight of 2361.2 g (p < 0.05), a total weight gain of 1412.8 g (p < 0.05), and improved feed efficiency with a feed conversion of 2.00 (p < 0.05), during which feed intake was lower than in the other groups. \u0000\u0000Conclusion: Microbial additives with lactic acid activity are a cost-effective and feasible solution for broiler chicken productivity. \u0000\u0000Keywords: broilers, lactic acid bacteria, probiotic mixture, productive indicators.","PeriodicalId":506834,"journal":{"name":"Veterinary World","volume":"26 49","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141699790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Raising double-muscled breed cattle and their crossbreds in the tropics: insight from growth models","authors":"Ummi Noorhakimah Abdullah, G. Y. Meng","doi":"10.14202/vetworld.2024.1504-1513","DOIUrl":"https://doi.org/10.14202/vetworld.2024.1504-1513","url":null,"abstract":"Background and Aim: In tropical conditions, modeling the predictive parameters of live weight, including those at birth, pre-weaning, post-weaning, finishing, and maturing, and the average daily gain, is challenging. The heat load significantly influences the growth rate and final mature weights in the tropics. The study compared the growth rates of Kedah-Kelantan (KK), Brahman (BRAH), and Belgian Blue (BB) crossbred calves. \u0000\u0000Materials and Methods: The study conducted growth analysis using the non-linear regression growth models as it approximates the sex, breed, and growth physiology changes in beef cattle. It is supported by the utility of the most common growth functions (Brody, Logistic, von Bertalanffy, and Richard’s model) in normal-muscled tropical breeds and double-muscled crossbred beef cattle in the tropics. \u0000\u0000Results: The BB crossbreds outperformed the KK and BRAH breeds by 50%–100% in live weight gains under tropical conditions. The crossbreds display the double-muscled effect and highlight the advantages of heterosis, making them suitable for upgrading local herds. The study’s findings on the growth characteristics of BB crossbred cattle were best described by the von Bertalanffy growth model, which had a high coefficient of determination (R2 > 0.8) and yielded estimated mature weights of 527.5 kg for males and 518.5 kg for females. \u0000\u0000Conclusion: According to results, raising BB crossbreds in the tropics as a solution to ensure a sustainable beef supply could yield significant growth and economic benefits. \u0000\u0000Keywords: beef cattle, Belgian blue crossbreds, Brahman, double-muscled, growth performance, Kedah-Kelantan, non-linear regression growth functions.","PeriodicalId":506834,"journal":{"name":"Veterinary World","volume":"8 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141699201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in the metabolomic profiles of mammary secretion in relation to dam litter size and parity number in Black Bengal goats","authors":"Tien Thi Phuong Vo, C. Buranakarl, Sumonwan Chamsuwan, S. Thammacharoen, Panupat Ratchakom, M. Nuntapaitoon, S. Settachaimongkon","doi":"10.14202/vetworld.2024.1469-1481","DOIUrl":"https://doi.org/10.14202/vetworld.2024.1469-1481","url":null,"abstract":"Background and Aim: The colostrum is essential for a kid’s survival and development. The metabolomic profiles of mammary secretion in goats are limited. This study investigated the metabolomic profiles of mammary secretion in purebred Black Bengal goats and their relationships with litter size and parity number. \u0000\u0000Materials and Methods: 500 MHz nuclear magnetic resonance was used to analyze the metabolomic profiles of 43 colostrum and milk samples collected on delivery day and day 7 after parturition, respectively. \u0000\u0000Results: Fifty-one metabolites were distinguished between colostrum and milk based on heatmap visualization and hierarchical cluster analysis. In colostrum, most compounds were present in significantly greater amounts than in milk. Milk of goats with multiple litter sizes had higher levels of lactose while fat, protein, total solids, solid not fat, and most of the metabolites were lower. The parity number of dams shows no difference in the composition of all components between primiparous and multiparous goats. \u0000\u0000Conclusion: The components in colostrum were significantly more concentrated than those in milk. The multiple litter sizes in dams led to a significant impact on the composition of lactose and other milk metabolites.\u0000\u0000Keywords: black Bengal goats, colostrum, litter size, metabolite, milk, parity number.","PeriodicalId":506834,"journal":{"name":"Veterinary World","volume":"10 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141693252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of knowledge, attitudes, and practices on vaccine usage among small ruminant farmers in the Northern Region of Bangladesh","authors":"Md. Sodrul Islam, A. Mondal, Md. Rabiul Auwul, Tahrima Islam, Obaidul Islam, Afroja Yasmin, Md. Abdullah Al Mahmud, A. Z. Haque, Mahmuda Begum, Jahid Hasan Tipu, Ysharzya Mojumder, Manna Roy, Md. Ashraful Islam","doi":"10.14202/vetworld.2024.1435-1448","DOIUrl":"https://doi.org/10.14202/vetworld.2024.1435-1448","url":null,"abstract":"Background and Aim: Small ruminants require vaccines to prevent and manage diseases. Unfortunately, no studies have been conducted in Bangladesh to assess the knowledge, attitudes, and practices (KAP) of small ruminant farmers (SRF) regarding vaccine use against infectious diseases, affecting the success of vaccination campaigns. The present study aims to assess SRF’s KAP regarding vaccines, revealing gaps and barriers to efficient vaccination. \u0000\u0000Materials and Methods: Two hundred and twenty-eight SRF in northern Bangladesh were surveyed in a cross-sectional study. Data were collected from random participants through face-to-face interviews using a structured questionnaire. KAP levels were categorized as “good” or “poor” and “positive” or “negative” using a scoring method with a 60% cutoff. The analysis comprised the utilization of descriptive statistics as well as logistic regression models. \u0000\u0000Results: Results showed that most participants were female (60.5%), aged 31–40 (34.2%), with secondary education (28.1%), and vaccination training (22.8%). While 75% knew about vaccines, only 37.3% understood their role in preventing infectious diseases, and 63.6% in reducing antibiotic use 68.4% of farmers were aware of negative drawbacks, and 61.8% reported vaccinating their herds. About 42.1% of the farmers had good knowledge, 52.6% had a positive attitude, and 22.8% followed good practices. Female farmers with graduate degrees and 6–10 years of goat farming experience, but not those with vaccination training, demonstrated stronger knowledge. Female farmers with a graduate degree and 6–10 years of goat farming experience displayed positive attitudes. Female goat farmers from Thakurgaon had a higher likelihood of following good vaccination practices than those with vaccination training. \u0000\u0000Conclusion: The study unearths disparities in KAP scores among farmers. To effectively address KAP gaps concerning vaccine usage and prevent potential infectious diseases, it is essential to design focused educational and training programs. About 52.6% of SRF hold a positive view toward vaccines. \u0000\u0000Keywords: Bangladesh, knowledge, attitudes, and practices, small ruminant farmers, vaccine use.","PeriodicalId":506834,"journal":{"name":"Veterinary World","volume":"25 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141693601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytogenic cocktails fed in different feeding regimes as alternatives to antibiotics for improving performance, intestinal microbial, and carcass characteristics of slow growth chickens","authors":"T. Pasaribu, A. P. Sinurat, Marsudin Silalahi, J. A. Lase","doi":"10.14202/vetworld.2024.1423-1429","DOIUrl":"https://doi.org/10.14202/vetworld.2024.1423-1429","url":null,"abstract":"Background and Aim: The phytogenic cocktail (PC) is a unique combination of natural plant extracts consisting of coconut shell smoke, clove leaf extract, and mangosteen rind extract, predominantly containing phenol, eugenol, and α-mangostin. Chicken performance can be improved by its antibacterial properties. This study aimed to test PC as a replacement for antibiotic growth promoters (AGPs), assessing its impact on performance, intestinal microbes, and carcass traits in slow growth KUB chickens. \u0000\u0000Materials and Methods: Two hundred and forty KUB chicks were distributed randomly to five dietary groups. Each group constituted six replicates, one replicate contained eight chicks. The treatments included the control diet (CD) with no additives, CD with 50 ppm Zinc bacitracin as an additive (AGPs), CD paired with 198 mL PC/ton feed provided for the initial 12 weeks (PC1), CD with 198 mL PC/ton feed given for the first 4 weeks (PC2), and CD supplied with 198 mL PC/ton feed for the first 8 weeks (PC3). Performance and mortality indicators were assessed during the feeding stage up to 12 weeks of age, while intestinal total microbial count and carcass characteristics were determined at 12 weeks. Duncan’s multiple-range test identified differences among the treatments in the randomized experiment. \u0000\u0000Results: The AGPs group weighed significantly more (p < 0.05) than PC2 but not significantly different (p > 0.05) from Control, PC1, and PC3 at 4 weeks. At 8 weeks, there was no significant difference (p > 0.05) in the body weight (BW) between the AGP, CD, and PC groups. The AGPs group had a significantly greater BW than PC1 and PC2 at 12 weeks (p < 0.05), but was comparable to CD and PC3 (p > 0.05). During the starter phase (0–4 weeks), dietary addition of AGPs or PCs significantly reduced feed intake (p < 0.05); however, no significant effect (p > 0.05) was observed during the later feeding periods (0–8 or 0–12 weeks). During the starter period, PC3 yielded the best feed conversion ratio, slightly surpassing AGPs and significantly (p < 0.05) outperforming CD. No significant variations (p > 0.05) were detected in the carcasses among the treatments. The reduction of abdominal fat relative weight was significant (p < 0.05) during the first 8 weeks of PC feeding. After the 12-week trial, no significant difference (p > 0.05) was observed in the proportionate weights of the crop, proventriculus, gizzard, pancreas, cecum, spleen, bursa of Fabricius, heart, and liver. The reduction in the intestinal microbe population due to AGPs or PC was not statistically significant (p > 0.05). About 100% viability was confirmed by the absence of mortality throughout the study. \u0000\u0000Conclusion: PC supplementation in KUB chicken feed enhances their performance. The optimal feeding regimes were effective during the first 8 weeks of age. In the 0–4 week time frame, feeding the PC to the chicken worsened performance whereas no improvement was observed in the 0–12 week period. The applic","PeriodicalId":506834,"journal":{"name":"Veterinary World","volume":"70 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141710991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of single-nucleotide polymorphisms in growth hormone and insulin-like growth factor-1 genes related to growth traits in purebred and crossbred quails","authors":"Mohamed H. Khalil, Eman A. Elattar, Ayman S. EL-Seedy, M. Shebl","doi":"10.14202/vetworld.2024.1482-1489","DOIUrl":"https://doi.org/10.14202/vetworld.2024.1482-1489","url":null,"abstract":"Background and Aim: There is a limited amount of research conducted on quail breeding domestically and internationally, particularly at the molecular level. This study aimed to detect single-nucleotide polymorphisms in the growth hormone (GH) and insulin-like growth factor-1 (IGF-1) genes across two quail varieties and their hybrids correlate these genetic factors with body weight (BW) and growth rate at 0 and 6 weeks, and assess crossing effects. \u0000\u0000Materials and Methods: White and Japanese quail were crossed. Simultaneously producing pure varieties and crosses (genotypes) was achieved through this breeding strategy. Fifty females from each genotype were randomly selected for blood sampling. Genomic DNA was extracted and amplified from the blood using the DNeasy blood kit (Qiagen, Germany). Nucleotide polymorphism between quail genotypes was determined through DNA sequencing. \u0000\u0000Results: Two types of alleles (A and B) for the GH gene in quails showed significant genotypic differences (AA, BB, and AB). The quail carried a mutated IGF-1 gene. For growth traits, substantial positive heterosis was detected. \u0000\u0000Conclusion: The genotype AA had the highest BW and weight gain. The white variety can act as a sire, and both white and Japanese varieties can function as dams to improve growth traits. The growth characteristics of the hybrids surpassed those of the original varieties. \u0000\u0000Keywords: crossing effects, genes for growth hormone and insulin, growth, polymorphism, quail.","PeriodicalId":506834,"journal":{"name":"Veterinary World","volume":"2 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141700480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}