Journal of Advances in Medicine and Medical Research最新文献

{"title":"Sleep Disorders and Quality of Life of Women in Menopausal Transition and Postmenopausal Assisted in Primary Health Care: A Cross-Sectional Observational Study Protocol","authors":"Leandro Victor Silva Ribeiro, L. Pasqualotto, Newton Santos de Faria Júnior","doi":"10.9734/jammr/2024/v36i75509","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i75509","url":null,"abstract":"Aims: The objective of the study will be to evaluate the presence of sleep disorders, sleep quality and life of women in the menopausal transition and postmenopausal assisted in primary health care (PHC) in Divinópolis/MG. \u0000Study Design: Cross-sectional observational. \u0000Place and Duration of Study: PHC in the municipality of Divinópolis, Minas Gerais, Brazil, between January and December 2023. \u0000Material and Methods: The present study will be carried out by professors and students of the University of the State of Minas Gerais (UEMG), Divinópolis Unit, with women recruited from PHC in the municipality of Divinópolis/MG, after consenting to participate in the study, by signing the Informed Consent Form (ICF). The sample will be consecutive and of convenience and then stratified according to sociodemographic variables, presence or absence of sleep disorders, sleep quality, quality of life and other variables pertinent to the study. \u0000Discussion: Due to the lack of professional performance in primary care for sleep disorders,                           it is necessary to study the concomitant changes between the menopausal transition and postmenopausal processes. Given the aspects related to these disorders, there is a need for a more in-depth look at the factors that can interfere with sleep quality during this transition. \u0000Conclusion: This study protocol aims to investigate sleep disorders and the quality of sleep and life in women during the menopausal and postmenopausal transition phases. The research seeks to identify data demonstrating the changes that occur during these phases.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":"44 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141663828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comprehensive Analysis of Outcome of Colectomy in Colorectal Cancer Patients: An Insight from Private Center from the North of Brazil","authors":"Charles Cruz e Silva, Weany Jeniffer Costa da Conceição, Paulo Victor Ataliba Morais, Suellen Emilliany Feitosa Machado, Raissa Norat Vanetta","doi":"10.9734/jammr/2024/v36i75507","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i75507","url":null,"abstract":"Aims: to analyze results of partial or total colectomies conducted in colorectal cancer (CRC) patients at a private hospital in Belém, Pará, Brazil. \u0000Study Design: The study was cross-sectional, retrospective and descriptive. Place and duration of the study: the study analyzed medical records of CRC patients subjected to either partial or total colectomy at a hospital in Belém between 2018 and 2022. \u0000Methods: The research abided by ethical norms including the Norms for Research Involving Humans of the Health National Center. The target population was composed of CRC patients of both sexes. The definitive International Classification Diseases (ICD) C18 and C19 and the following keywords “colorectal cancer”, “colon cancer”, “partial colectomy” and “total colectomy” were used to search the medical records. The analyzed variables were: epidemiologic factors, pre-operative variables, peri-operative and post-operative variables, bleeding, oncological factors, presence of compromised lymph nodes, and early and late complications. \u0000Results: After searching the hospital records, it was found that 414 patients were hospitalized with CRC between 2018 and 2022. Of these, 288 were not considered for the study due to the exclusion criteria and, therefore, 122 patients were included in the research. Fistulas were the most common early complication and recurrence the most common late complication with significant association to the presence of positive lymph nodes to pathological staging (p=0.025). Early deaths were most recurrent in stage IV (p=0.003). No statistical relevance was found between the type of colectomy and the presence of early (p=0.906) and late (p=0.237) complications. As for surgeries, conventional surgeries were related to higher rates of complications and prolonged admission. \u0000Conclusion: Negative outcomes for CRC patients are related to pathological staging and patients with positive lymph nodes presented the worst results. In addition, robotic surgery and laparoscopy were related to faster recovery and lessened early complications.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":"105 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141666128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitigating the Negative Impact of Social and Environmental Factors on Mental Well-being through Community-based Interventions","authors":"I. Folorunsho, N. M. Harry, Gibson Anugwom","doi":"10.9734/jammr/2024/v36i75501","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i75501","url":null,"abstract":"Community-based interventions (CBI) effectively address the negative impact of social and environmental factors on mental well-being by leveraging community resources, strengths, and resilience. Successful examples, such as the Friendship Bench in Zimbabwe and the Community Reinforcement and Family Training (CRAFT) program, demonstrate the importance of community engagement and multi-sector partnerships in creating culturally responsive and sustainable mental health programs.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":" 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141680844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Most Cited Articles in Resinous Infiltrates: A Bibliometric Analysis","authors":"Ana Flávia César Guimarães, Júlia de Oliveira Rocha, Adriana da Silva Torres, Olga Beatriz Lopes Martins, Moisés de Matos Torres, Cíntia Tereza Pimenta de Araújo","doi":"10.9734/jammr/2024/v36i75499","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i75499","url":null,"abstract":"Aims: To identify trends and growth in knowledge related to Resin Infiltrants, through a bibliometric review. \u0000Study Design:  Bibliometric review. \u0000Methodology: A search was carried out in the Clarivate Analytics Web of Science database, using the terms (infiltrative resin OR resin infiltration) AND (white spot lesions OR white spots OR WSL OR Enamel demineralization OR orthodon* OR defect* OR hypoplas* OR discolor * OR dental fluorosis OR tooth demineralization OR calcification, tooth OR tooth discoloration OR dental enamel). Paired selection of manuscripts was carried out. The initial search identified 599 articles. After comparing titles and abstracts, the 50 most cited manuscripts involving Resinous Infiltrants were listed in order of classification. \u0000Results: The most cited article in the top 50 was Frencken et al. in [1]. The earliest manuscript of this bibliometric analysis was published in 2001 by Robinson et al. in Caries Research and was cited 72 times, while two articles were the most recent, published in 2019 by Urquhart et al. in the Journal of Dental Research, it was cited 112 times and by Coelho Ased et al. in the Journal of Esthetic and Restorative Dentistry, cited 35 times. The citation distribution line shows high peaks in 2010 and 2012. The institutions that stood out the most were Charité Universitat Medizin Berlin, followed by Universitat zu Kiel. The main country was Germany. Among the main journals are the Journal of Dentistry and the publisher Elsevier. In total, 274 keywords were used. The period of 2010 was the period with the greatest concentration of publications and the most productive. \u0000Conclusion: The bibliometric review carried out in this study revealed the growing interest and research around the use of Resinous Infiltrants as an effective and minimally invasive alternative to address white spot lesions and tooth decay.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":"13 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141698480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of Leiomyosarcoma of the Femoral Artery; Rare Location and Management at an Advanced Stage","authors":"Hamadoun Traoré, Andy J. Kouanga, Mohammed Anouar Mokhlis, Mendes Papys, C. Elm’hadi, R. Tanz, Hassan Errihani","doi":"10.9734/jammr/2024/v36i75500","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i75500","url":null,"abstract":"Vascular leiomyosarcomas are extremely rare tumours, accounting for less than 1% of all malignant tumours. Venous leiomyosarcomas occur five times more frequently than arterial leiomyosarcomas. These are most often found in the large vessels and less than 50% occur in the peripheral circulation. Median survival has not been quantified. It can be good if radical surgery is performed. Treatment, whatever the stage, requires multidisciplinary management. Surgery with en bloc resection remains the treatment of choice for localised disease; in patients with unresectable locally advanced or metastatic disease, systemic treatment with essentially palliative aims may be proposed. Anthracycline-based treatment is the standard first-line therapy. \u0000We report a case report of a 50-year-old female patient with local, pulmonary and bone relapse of an operated left femoral artery leiomyosarcoma in whom we undertook palliative mono-chemotherapy. \u0000Conclusion: Vascular leiomyosarcomas are extremely rare tumours, accounting for less than 1% of all malignant tumours. Median survival is dramatic for metastatic patients, with a median survival of 8 months, ranging from 5 to 20 months. Surgery remains the standard curative treatment for the localised stage; for stage 4, single chemotherapy is the treatment of choice.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":"45 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141715231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Employment-Based Contingency on Treatment Enrollment, Retention, and Long-Term Abstinence among Individuals with Substance use Disorder: A Systematic Review","authors":"N. M. Harry, Ibrahim Folorunsho, Nnenna Okafor, Oluwatosin Arubuolawe, Gibson Anugwom","doi":"10.9734/jammr/2024/v36i65455","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i65455","url":null,"abstract":"Background and Objective: Substance use disorders (SUD) remain a major public health concern and represent a significant cause of morbidity and mortality. Our goal in this study is to explore and determine the effect(s) of employment-based contingency (EBC) on enrolling SUD individuals into treatment, the rate of treatment adherence, and the rate of post-treatment abstinence. \u0000Methods: PubMed and Google Scholar search was conducted using the search terms ((substance use disorder) AND (unemployment)) OR (therapeutic workplace)), for randomized controlled trials (RCT) published between 2012 and 2022, reporting on participants between ages 18 and 65 years who use opioids, cocaine or alcohol. \u0000Results: Seven RCT which met the criteria and addressed the study objectives had a total of 389 participants. Three RCT of the seven with 203 participants found EBC to positively impact the rate of enrollment to treatment with 100%, 92%, and 100% enrollment rates in the respective studies. Three articles with 172 participants found a higher rate of treatment adherence and retention to treatment among EBC participants compared to the control group. There was more naltrexone-positive urine in the EBC group compared to control (72% vs. 21%, with a p-value of .01), and 74% (EBC) vs 26% (control) participants completed treatment. Four articles with 238 participants found that EBC improved the rate of abstinence by over 50%, which is double the rate among the control group without EBC. \u0000Conclusion: EBC is effective in improving SUD treatment enrollment, treatment adherence, and post-treatment abstinence, however, the efficacy may be dependent on how much is earned as an incentive.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":"57 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141111485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osteonecrosis Related to the use of Osteoporosis Medications: An Integrative Literature Review","authors":"Rafaela Melo Santos, Edson Vinicius Santos Almeida, Naiara Lima Fagundes, Laila Eduarda Silva Pires, Luiz Eduardo de Góes Ladeia","doi":"10.9734/jammr/2024/v36i65453","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i65453","url":null,"abstract":"Aims: Understand the relationship between bisphosphonates used in the treatment of osteoporosis and mandibular osteonecrosis, its outcomes, and implications for patient management, seeking to understand the best strategies for preventing and managing this condition. \u0000Study Design:  Integrative literature review. \u0000Methodology: The research methodology was outlined as exploratory and qualitative, aiming to provide a deeper understanding of the problem under study and generate hypotheses. Works published in the last 10 years (2014 to 2024) were used, including books, articles, periodicals, and online resources. For the selection of the sample, priority was given to works indexed in national and international journals, available in full. The electronic search was conducted in databases such as Latin American and Caribbean Health Sciences Literature (LILACS), Medical Literature Analysis and Retrieval System Online (MEDLINE), and Scientific Electronic Library Online (SciELO). The descriptors used were \"Antiresorptive\", \"Bisphosphonate\", \"Mandible\" and \"Bone necrosis\", registered in the Health Sciences Descriptors (DeCS), combined with the Boolean operators \"AND\" and \"OR\". The inclusion criteria for the selection of articles were to be original, addressing the theme of the study, to be indexed in the selected databases, written in Portuguese or English, and to be free of charge. Studies that were not related to the theme, duplicates and that did not fit into the proposed analysis period were excluded. \u0000Results: Through the studies surveyed, an association between the incidence of osteonecrosis and the use of osteoporosis drugs, such as bisphosphonates, especially osteonecrosis of the jaws (ONJ), was observed. Bisphosphonates, widely used in the treatment of osteoporosis, inhibit bone resorption, but their long-term use is associated with complications, including ONJ. Risk factors such as advanced age, long-term use of medications, comorbidities such as diabetes, and genetic predisposition have been identified. \u0000Conclusion: Management of ONJ involves conservative therapies and surgical procedures, which are especially effective when the condition is diagnosed early. On the other hand, therapeutic alternatives, such as photodynamic therapy, are being investigated, highlighting the need for controlled clinical trials to determine their efficacy.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":"118 47","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141115678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Report on Plasma Cell Leukemia Presenting as a Chest Wall Mass","authors":"N. Zaghba, Z. Benmerzouq, H. Benjelloun, K. Chaanoun, N. Yassine","doi":"10.9734/jammr/2024/v36i65452","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i65452","url":null,"abstract":"Plasma cell leukemia (PCL) is an uncommon neoplasm of plasma cells with an aggressive clinical course and a poor outcome, even with the current standard of care. It can occur either de novo (primary PCL) or as a progression of multiple myeloma (MM). This disease has unique diagnostic criteria, but certain genetic markers and clinical features may overlap with multiple myeloma (MM). Due to the low prevalence of PCL, guidelines on its management are extrapolated from the management of MM and are based on small retrospective studies and case reports/series. We report the case of a sixty-nine-year-old man referred to the hematology department for the diagnosis of pPCL, revealed by thoracic plasmacytomas mimicking a thoracic neoplasm. The diagnostic approach, management, and outcomes of PCL are discussed.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":"44 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141113521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19 Pandemic and Impacts on Cervical Cancer Screening and Treatment Programs: A Narrative Review","authors":"Sebastião Kauã de Sousa Bispo, Alex Patrick Oliveira da Silva, Natasha Cristina Oliveira Andrade, Karina Faine da Silva Freitas, Yasmin Martins de Sousa, Danielle Etienne de Oliveira Bezerra Lima, Ana Maria Dias Corrêa dos Santos, T. D. N. Soares, Suziane do Socorro dos Santos, Marcela Raíssa Asevedo Dergan, Gal Caroline Alho Lobão, Milena Silva dos Santos Magalhães, Perla Katheleen Valente Corrêa, Mayara Annanda Oliveira Neves Kimura, J. S. Freitas, D. Sardinha","doi":"10.9734/jammr/2024/v36i65451","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i65451","url":null,"abstract":"Cervical cancer is a significant global health issue affecting both developing and industrialised countries. Annually, over 500,000 women are diagnosed with cervical cancer, resulting in more than 300,000 deaths worldwide. Notably, around 90% of cervical cancer cases occur in low- and middle-income countries that lack organised HPV screening and vaccination programs. The condition is commonly known as the 'disease of disparity' due to the significant difference in incidence and mortality rates between low- and middle-income countries and high-income countries. The objective of this review is to describe the impact of the COVID-19 pandemic on cervical cancer, based on a narrative literature review. Experts in global gynecological health have reported that cervical cancer screening programs, already scarce in low- and middle-income countries, have been severely impacted by COVID-19 and cuts in UK foreign aid. The pandemic has caused delays in diagnosis due to the interruption of health services by COVID-19 control measures, as well as affecting the follow-up and treatment of women who have already been diagnosed. Following the pandemic restrictions, incidence and mortality rates have increased due to the failure of pap smear screening. The lack of screening services has disproportionately affected women who are most vulnerable due to social factors. In the long term, this may have a greater impact on low- and middle-income countries.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":"121 28","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141125169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of DNA Methylation in Offsprings of Individuals with Type 2 Diabetes Mellitus","authors":"Sukhraj Kaur, R. Kapahi, I. Grover, Ritu Sharma, P. Sandhu","doi":"10.9734/jammr/2024/v36i65450","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i65450","url":null,"abstract":"Introduction:  Epigenetic is study of changes in gene expression that occur by changing the DNA methylation and remodeling chromatin. It may also be affected by the environment. It is an important pathogenic mechanisms in complex multifactorial diseases such as type two diabetes. Recent genome-wide association studies have identified a number of genetic variants that explain some of the inter individual variation in diabetes susceptibility. Thus keeping in view, the role of epigenetic mechanisms particularly DNA methylation, the present study was conducted to find out DNA methylation (Whole DNA) in offsprings of individuals with type 2 Diabetes Mellitus. \u0000Methods: For the present study, the families of one hundred Diabetic individuals were enrolled. All the off springs of diabetics above the age of 18 years were recruited for the present study. All the samples collected were analyzed for Fasting plasma glucose, Glycosylated Hemoglobin, Lipid profile complete and DNA methylation (5mcytosine). \u0000Results: The study included 100 diabetic individuals and their off springs in the age range of 18-35 years. DNA methylation measured as 5mc% was significantly (p<0.001) more in IFG and Diabetic offsprings as compared to normal individuals both males and females. \u0000Conclusions: Altered DNA Methylation in individuals of the age group 18-24 years indicates towards deranged metabolism in these individuals, leading to impaired fasting glucose and making them more prone to type 2 Diabetes Mellitus and its complications at a later age.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":"104 44","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141124728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}