{"title":"The king has been dethroned.","authors":"Dominick Bossé","doi":"10.5489/cuaj.9046","DOIUrl":"10.5489/cuaj.9046","url":null,"abstract":"","PeriodicalId":50613,"journal":{"name":"Cuaj-Canadian Urological Association Journal","volume":"18 12","pages":"391"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11623327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pocharapong Jenjitranant, Jose de Jesus Cendejas-Gomez, Adam Power, Nicholas E Power
{"title":"A novel technique for proximal inferior vena cava control during tumor thrombectomy using the COBRA-OS balloon.","authors":"Pocharapong Jenjitranant, Jose de Jesus Cendejas-Gomez, Adam Power, Nicholas E Power","doi":"10.5489/cuaj.8772","DOIUrl":"10.5489/cuaj.8772","url":null,"abstract":"","PeriodicalId":50613,"journal":{"name":"Cuaj-Canadian Urological Association Journal","volume":" ","pages":"E350-E352"},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11534402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141560189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marissa Le Gallee, Logan Richard, Vanessa Di Palma, Nathalie Kupfer, Erin Kelly, Jane Schulz, May Sanaee
{"title":"Case series - Urethra diaries Not every bulge is pelvic organ prolapse.","authors":"Marissa Le Gallee, Logan Richard, Vanessa Di Palma, Nathalie Kupfer, Erin Kelly, Jane Schulz, May Sanaee","doi":"10.5489/cuaj.8759","DOIUrl":"10.5489/cuaj.8759","url":null,"abstract":"","PeriodicalId":50613,"journal":{"name":"Cuaj-Canadian Urological Association Journal","volume":" ","pages":"E360-E364"},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11534399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141560192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Asad Ullah, Naema Daino, Abdul Qahar Khan Yasinzai, Kue Tylor Lee, Amir Humza Sohail, Aman Goyal, Abdul Waheed, Asif Iqbal, Nabin R Karki
{"title":"Clinicopathologic and survival patterns among prostate carcinosarcoma patients in the U.S. An analysis of SEER database.","authors":"Asad Ullah, Naema Daino, Abdul Qahar Khan Yasinzai, Kue Tylor Lee, Amir Humza Sohail, Aman Goyal, Abdul Waheed, Asif Iqbal, Nabin R Karki","doi":"10.5489/cuaj.8769","DOIUrl":"10.5489/cuaj.8769","url":null,"abstract":"<p><strong>Introduction: </strong>Prostatic carcinosarcoma comprises <1% of all prostate neoplasms. The literature on this disease is limited to a few case studies, primarily due to the rarity of this malignancy. We aimed to investigate the demographic, clinical, and histologic factors, prognosis, and survival of prostatic carcinosarcoma.</p><p><strong>Methods: </strong>The Surveillance, Epidemiology, and End Results (SEER) database was used to identify patients with prostatic carcinosarcoma from 2000-2018. Demographic and clinical data, including age, race, sex, tumor grade, stage, tumor size, lymph node status, metastasis, and treatment modalities, were recorded.</p><p><strong>Results: </strong>Patients with prostatic carcinosarcoma had a median age of 72 years at diagnosis, most cases among White individuals (93%). When reported, the histologic grade comprised moderately differentiated (3.3%), poorly differentiated (56.7%), and undifferentiated/anaplastic (40%) subtypes. In patients with reported data, tumor size varied between 2-5 cm (15.8%) and >5 cm (84.2%). Distant metastasis most commonly occurred in the liver (12.5%) and lung (12.5%), followed by the bone (8.3%). The most common treatment performed was surgery with radiation (32.4%). The five-year overall survival was 11.9%.</p><p><strong>Conclusions: </strong>Prostatic carcinosarcoma affects men in the seventh decade of life. Regional and distant tumor stage is considered an indicator of survival. Prostate carcinosarcoma is rare; due to its aggressive nature, a deeper understanding, and an improved personalized therapeutic approach are necessary for improving patient outcomes in this challenging arena of oncology.</p>","PeriodicalId":50613,"journal":{"name":"Cuaj-Canadian Urological Association Journal","volume":" ","pages":"E334-E338"},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11534400/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141560193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Alfonso Nieva-Posso, Daniel Andrés Nieva-Posso, Herney Andrés García-Perdomo
{"title":"Implications of using conversational robots (chatbots) in uro-oncology A patient and physician perspective.","authors":"Daniel Alfonso Nieva-Posso, Daniel Andrés Nieva-Posso, Herney Andrés García-Perdomo","doi":"10.5489/cuaj.8762","DOIUrl":"10.5489/cuaj.8762","url":null,"abstract":"<p><p>Chatbots, or conversational robots, have become a strategy or support tool for urologic patient care, diagnostic communication, and treatment. With regard to patients, studies have shown that chatbots can answer medical questions with similar percentages of acceptability as urologists. In addition, they can contribute to patient education, allowing them to ask questions that do not arise during medical consultation. They have also proven to be good tools for health promotion and disease prevention. These benefits can also serve doctors, as robots can support medical consultation and the reading of medical records, making patient care more efficient; however, there are several limitations, including the accuracy of bot-generated answers and the acceptability that urologists give to this type of tool.</p>","PeriodicalId":50613,"journal":{"name":"Cuaj-Canadian Urological Association Journal","volume":" ","pages":"E346-E349"},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11534396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141560195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Steven A Kaplan, Merycarla Pichardo, Edwin Rijo, Gustavo Espino, Ramon Rodriguez Lay, Rafael Estrella
{"title":"Long-term outcomes after treatment with Optilume BPH Four-year results from the EVEREST study.","authors":"Steven A Kaplan, Merycarla Pichardo, Edwin Rijo, Gustavo Espino, Ramon Rodriguez Lay, Rafael Estrella","doi":"10.5489/cuaj.8737","DOIUrl":"10.5489/cuaj.8737","url":null,"abstract":"<p><strong>Introduction: </strong>The purpose of this study was to gather initial safety and efficacy data with the Optilume<sup>®</sup> BPH Catheter System for the treatment of lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH).</p><p><strong>Methods: </strong>A total of 80 men with moderate-to-severe LUTS secondary to BPH were enrolled and treated with the Optilume BPH Catheter System. Symptoms were evaluated using the International Prostate Symptom Score (IPSS) and Benign Prostatic Hyperplasia-Impact Index (BPH-II). Improvement in urinary flow and relief of obstruction was evaluated by way of peak urinary flow rate (Qmax) and postvoid residual urine volume (PVR). Subjects were prospectively queried for adverse events at each study visit, and relatedness to the study device was evaluated by the investigators, as well as centrally adjudicated by the study principal investigator.</p><p><strong>Results: </strong>Previous reports of symptom improvement in this cohort were maintained through four-year followup, with a significant reduction in IPSS and IPSS quality of life maintained through four years (-12.1, -2.8, respectively). Clinically meaningful improvement in Qmax was maintained in the majority of subjects, with an average improvement from baseline of +5.6 mL/sec. No treatment-related adverse events were reported in the long-term followup period.</p><p><strong>Conclusions: </strong>Long-term followup through four years for subjects treated with the Optilume BPH Catheter System indicates durable outcomes in symptom improvement and functional improvement in flow rate. These results indicate the unique mechanism of action for Optilume BPH successfully achieves an immediate mechanical effect that is maintained long-term through incorporation of paclitaxel to maintain patency.</p>","PeriodicalId":50613,"journal":{"name":"Cuaj-Canadian Urological Association Journal","volume":" ","pages":"E319-E325"},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11534392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141560197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michel Normand, Jean-Philippe Haymann, Michel Daudon
{"title":"Medical treatment of uric acid kidney stones.","authors":"Michel Normand, Jean-Philippe Haymann, Michel Daudon","doi":"10.5489/cuaj.8774","DOIUrl":"10.5489/cuaj.8774","url":null,"abstract":"<p><strong>Introduction: </strong>The prevalence of uric acid (UA) stones increases regularly due to its high correlation with obesity, hypertension, metabolic syndrome, type 2 diabetes, and aging. Uric acid stone formation is mainly due to an acidic urinary pH secondary to an impaired urinary ammonium availability responsible for UA rather than soluble urate excretion. Alkalization of urine is therefore advocated to prevent UA crystallization and considered effective therapy.</p><p><strong>Methods: </strong>We report a large series of 120 patients with UA lithiasis who were successfully treated with potassium (K)-citrate for stone dissolution (n=75) and/or stone recurrence prevention (n=45) without any urologic intervention, with a median 3.14 years followup. The K-citrate was diluted in 1.5 L of water, avoiding gastrointestinal disorders.</p><p><strong>Results: </strong>Among 75 patients having stones in their kidney at initiation of therapy, a complete chemolysis was obtained in 88% of cases. Stone risk factors decreased under treatment, mainly due to increased diuresis, urinary pH, and citrate excretion. Treatment was stopped in only 2% of patients due to side effects, with no hyperkalemia onset despite a median urinary potassium increase of 44 mmol/day.</p><p><strong>Conclusions: </strong>Contrary to other reports, our data show that medical treatment of UA kidney stones is well-tolerated and efficient if regular monitoring of urinary pH is performed.</p>","PeriodicalId":50613,"journal":{"name":"Cuaj-Canadian Urological Association Journal","volume":" ","pages":"E339-E345"},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11534397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141560257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kiera Liblik, Liam Power, Daniel T Keefe, Jesse Ory
{"title":"Case series - Azoospermia to oligozoospermia following bilateral orchidopexy in adults with undescended testicles A Canadian first.","authors":"Kiera Liblik, Liam Power, Daniel T Keefe, Jesse Ory","doi":"10.5489/cuaj.8783","DOIUrl":"10.5489/cuaj.8783","url":null,"abstract":"","PeriodicalId":50613,"journal":{"name":"Cuaj-Canadian Urological Association Journal","volume":" ","pages":"E368-E370"},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11534401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141560191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rebecca Kindler, Arsha Venkat, Natalia L Arias-Villela, William Meeks, Emily Galen, Joel E Abbott, Meagan M Dunne, Julio G Davalos, Daniel C Rosen
{"title":"A 1.9 mm Trilogy lithotripter in mini percutaneous nephrolithotomy Description of technique and case outcomes.","authors":"Rebecca Kindler, Arsha Venkat, Natalia L Arias-Villela, William Meeks, Emily Galen, Joel E Abbott, Meagan M Dunne, Julio G Davalos, Daniel C Rosen","doi":"10.5489/cuaj.8714","DOIUrl":"10.5489/cuaj.8714","url":null,"abstract":"<p><strong>Introduction: </strong>We aimed to evaluate the novel use of a 1.9 mm Trilogy lithotripter probe with varying locations and composition of renal stones.</p><p><strong>Methods: </strong>We prospectively enrolled patients to undergo mini percutaneous nephrolithotomy (mPCNL) procedures using the 1.9 mm (instead of the standard 1.5 mm) Trilogy probe from August 2021 to April 2022. Several adjunctive irrigation measures compensated for reduced flow with the larger probe. The primary outcome was treatment efficiency. Patient demographics, preoperative demographics, and comorbidities, as well as real-time surgical data were extracted. Statistical analysis was performed using Kruskal-Wallis tests to compare stone type and location.</p><p><strong>Results: </strong>A total of 110 patients were included in this study. The median total treatment time was 6.8 minutes, median lithotripsy time was 3.3 minutes, median stone treatment efficiency was 0.34 mm/min, and treatment efficacy was 50.4 (lithotripter time/treatment time). Overall median lithotripter efficiency was 104.6 mm<sup>3</sup>/min. Treatment efficiency was similar among stone composition (p=0.245) and location (p=0.263). Lithotripter 3D and 1D efficiency was also similar among stone composition (p=0.637 and p=0.766, respectively). Lithotripter 1D efficiency was nearly twice as fast in the lower pole compared to other stone locations (p=0.010). The overall broken probe rate for this procedure was 12%, mostly at the beginning, suggesting a learning curve. Five patients had minor complications, including one patient who required admission to the hospital for postoperative pain management.</p><p><strong>Conclusions: </strong>The 1.9 mm Trilogy lithotripter can be effective in mPCNL procedures with the use of easily implementable adjunctive irrigation techniques, decreasing the gap between lithotripsy time and total treatment time.</p>","PeriodicalId":50613,"journal":{"name":"Cuaj-Canadian Urological Association Journal","volume":" ","pages":"E353-E359"},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11534393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141560196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}