Li He, Mengting Tian, Yixin Wen, Zhongkai Chen, Yanfei Cai, Jian Jin, Zhaoqi Yang
{"title":"MXene-Based Nanocomposite-Facilitated Photothermal Therapy by Preventing Expression of Heat Shock Protein 90","authors":"Li He, Mengting Tian, Yixin Wen, Zhongkai Chen, Yanfei Cai, Jian Jin, Zhaoqi Yang","doi":"10.1142/s0219581x23500862","DOIUrl":"https://doi.org/10.1142/s0219581x23500862","url":null,"abstract":"Photothermal therapy (PTT), as a tumor optical treatment strategy, has the characteristics of being minimally invasive, precise and safe in the treatment of tumors. However, the efficacy of photothermal treatment is usually affected by the photothermal conversion efficiency of the material and the expression of heat shock protein in tumor cells. Ti3C2, a kind of MXene, is a novel two-dimensional material with excellent photothermal conversion efficiency and multiple unique characteristics, making it a promising candidate for multimodal tumor therapy. Therefore, inhibiting the synthesis of heat shock protein 90 (HSP90) in the process of photothermal therapy can reduce the heat resistance of tumor cells, thereby improving the effect of photothermal therapy. In this study, we highlight the potential of utilizing hyaluronic acid (HA) modified Ti3C2 (Ti3C2@HA) as a carrier for delivering anti-sense oligonucleotides of HSP90 to inhibit HSP90 expression and enhance PPT efficacy. Under laser irradiation, the designed MXene-based nanocomposite (Ti3C2@ASO@HA) significantly inhibited the growth and effectively suppressed the migration of tumor cells. In addition, decreased expression of HSP90 is confirmed by western blotting. The results of this investigation provide a promising strategy for enhancing the photothermal therapy effects of tumor.","PeriodicalId":506026,"journal":{"name":"International Journal of Nanoscience","volume":"14 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140510869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Haneen Ali Jasim, Nisreen Khalid Fahad, S. M. Ali, Baida M. Ahmed, O. Dakhil
{"title":"Impact of Concentration on the Hydrothermally Synthesized NiO Nanosheets' Photocatalytic Activity","authors":"Haneen Ali Jasim, Nisreen Khalid Fahad, S. M. Ali, Baida M. Ahmed, O. Dakhil","doi":"10.1142/s0219581x23500874","DOIUrl":"https://doi.org/10.1142/s0219581x23500874","url":null,"abstract":"","PeriodicalId":506026,"journal":{"name":"International Journal of Nanoscience","volume":"154 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139145824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Synthesis of Cerium-Doped Zinc Oxide Nanocomposites and Their Application for Photocatalytic Degradation of Lambda-Cyhalothrin in Agricultural Runoff Under Natural Solar Irradiation","authors":"Mahadi Danjuma Sani, V. K. Abbaraju, N. Venugopal","doi":"10.1142/s0219581x23500898","DOIUrl":"https://doi.org/10.1142/s0219581x23500898","url":null,"abstract":"","PeriodicalId":506026,"journal":{"name":"International Journal of Nanoscience","volume":" 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139142290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. H. Salem, Kahtan A. Mohammed, Ameer Jawad Fadhl, Sameer Algburi, M. A. Alkhafaji, R. Zabibah, Z. F. Khudair, Shubham Sharma
{"title":"Eco-friendly synthesis of α-Fe2O3-Ag-ZnO nanocomposite with antibacterial, and RhB dye degradation properties using leaf extract","authors":"K. H. Salem, Kahtan A. Mohammed, Ameer Jawad Fadhl, Sameer Algburi, M. A. Alkhafaji, R. Zabibah, Z. F. Khudair, Shubham Sharma","doi":"10.1142/s0219581x23500886","DOIUrl":"https://doi.org/10.1142/s0219581x23500886","url":null,"abstract":"","PeriodicalId":506026,"journal":{"name":"International Journal of Nanoscience","volume":"22 s43","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139146911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Structurally Controllable Hay-Slag-Based Porous Carbons for Supercapacitor and CO<sub>2</sub> Adsorption Applications","authors":"Jiayu Min, Jiayi Zhu, Yutie Bi, Hongbo Ren","doi":"10.1142/s0219581x22500430","DOIUrl":"https://doi.org/10.1142/s0219581x22500430","url":null,"abstract":"Biomass-derived porous carbon materials were selectively and controllably prepared by carbonization of hay slag (HS) and activation with ZnCl 2 combined with Mg(NO[Formula: see text]H 2 O. The prepared porous carbon materials had an apparent multi-pore structure and a large specific surface area. In a 6[Formula: see text]mol/L KOH with a current density of 0.25[Formula: see text]A/g, the specific capacitance of the prepared sample was 220[Formula: see text]F/g. Further study showed that the optimal pore size range of porous carbon materials for electrode preparation was 0.8–1.2[Formula: see text]nm. At the same time, the porous carbon material had a good adsorption capacity for CO 2 , and the adsorbent performance was 3.09[Formula: see text]mmol/g at 0 ∘ C and 1 bar. Adsorbents with the pore size range of 0.5–0.8[Formula: see text]nm had the best CO 2 adsorption performance. This integrated strategy study expanded biomass-derived porous carbon materials with controllable pore structures to match different application strategies.","PeriodicalId":506026,"journal":{"name":"International Journal of Nanoscience","volume":"21 06","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147899677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}