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DEVELOPING A NOVEL POTENCY ASSAY TO ASSESS BONE MARROW-DERIVED EXTRACELLULAR VESICLES 开发一种新型效力测定法，以评估骨髓衍生的细胞外囊泡
Cytotherapy Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.169
E.F. Wiest, C. Zhang, R.B. Perkerson, A. Zubair
{"title":"DEVELOPING A NOVEL POTENCY ASSAY TO ASSESS BONE MARROW-DERIVED EXTRACELLULAR VESICLES","authors":"E.F. Wiest, C. Zhang, R.B. Perkerson, A. Zubair","doi":"10.1016/j.jcyt.2024.03.169","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.169","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141234565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DEVELOPMENT OF ANTAGONISTIC ANTI-BACE2 ANTIBODIES TO IMPROVE TYPE 2 DIABETES BY INDUCING ISLET β-CELL PROLIFERATION 通过诱导胰岛β细胞增殖来改善 2 型糖尿病的抗生物酶-BACE2 抗体的开发
Cytotherapy Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.199
C. Chen, K. Chuang
{"title":"DEVELOPMENT OF ANTAGONISTIC ANTI-BACE2 ANTIBODIES TO IMPROVE TYPE 2 DIABETES BY INDUCING ISLET β-CELL PROLIFERATION","authors":"C. Chen, K. Chuang","doi":"10.1016/j.jcyt.2024.03.199","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.199","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141235367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SCALABLE SOLUTIONS FOR EXPANSION OF NON-VIRALLY GENERATED CAR T CELLS 可扩展的非病毒生成汽车 t 细胞扩增解决方案
Cytotherapy Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.292
M. Ahmadi, D. Hayoun, M. Dotson, Y. Ji, X. de Mollerat du Jeu
{"title":"SCALABLE SOLUTIONS FOR EXPANSION OF NON-VIRALLY GENERATED CAR T CELLS","authors":"M. Ahmadi, D. Hayoun, M. Dotson, Y. Ji, X. de Mollerat du Jeu","doi":"10.1016/j.jcyt.2024.03.292","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.292","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141235115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NOVEL SOLUTIONS FOR QUALITY CONTROL IN GENE THERAPY VIRAL VECTOR DEVELOPMENT 基因治疗病毒载体开发质量控制的新解决方案
Cytotherapy Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.435
A. O’Hara, C. Richardson, C. Mozdzierz, H. Latif, G. Zhou
{"title":"NOVEL SOLUTIONS FOR QUALITY CONTROL IN GENE THERAPY VIRAL VECTOR DEVELOPMENT","authors":"A. O’Hara, C. Richardson, C. Mozdzierz, H. Latif, G. Zhou","doi":"10.1016/j.jcyt.2024.03.435","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.435","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141229268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IDENTIFICATION OF GENE REGULATORY NETWORKS ESSENTIAL FOR HEMATOPOIETIC PROGENITOR CELL AND T CELL EMERGENCE FROM HUMAN PLURIPOTENT STEM CELL VIA CRISPR SCREENS 通过crispr筛选鉴定人类多能干细胞中造血祖细胞和t细胞出现所必需的基因调控网络
Cytotherapy Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.191
M. Siu, E. Flaschner, Y. Michaels, P.W. Zandstra
{"title":"IDENTIFICATION OF GENE REGULATORY NETWORKS ESSENTIAL FOR HEMATOPOIETIC PROGENITOR CELL AND T CELL EMERGENCE FROM HUMAN PLURIPOTENT STEM CELL VIA CRISPR SCREENS","authors":"M. Siu, E. Flaschner, Y. Michaels, P.W. Zandstra","doi":"10.1016/j.jcyt.2024.03.191","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.191","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141230719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HYBRID CAR T CELLS WITH ENGINEERED FUEL FLEXIBILITY 具有工程燃料灵活性的混合动力汽车 T 细胞
Cytotherapy Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.370
B. Valentić, A. Kelly, E. Megill, Z. Gan, A.A. Shestov, F. Chen, N. Snyder, S. Ghassemi, N. Jones, S. Gill, R. O'Connor
{"title":"HYBRID CAR T CELLS WITH ENGINEERED FUEL FLEXIBILITY","authors":"B. Valentić, A. Kelly, E. Megill, Z. Gan, A.A. Shestov, F. Chen, N. Snyder, S. Ghassemi, N. Jones, S. Gill, R. O'Connor","doi":"10.1016/j.jcyt.2024.03.370","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.370","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141230922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
BIOPROCESS DESIGN AND OPTIMIZATION FOR EXTRACELLULAR VESCILES DERIVED FROM MESENCHYMAL STEM CELLS 间充质干细胞提取的细胞外蛭石的生物工艺设计与优化
Cytotherapy Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.164
M. Dehghani, E. Black, Z. Zhao, N. Haridas, S. Saha, D. Splan, M. Szczypka
{"title":"BIOPROCESS DESIGN AND OPTIMIZATION FOR EXTRACELLULAR VESCILES DERIVED FROM MESENCHYMAL STEM CELLS","authors":"M. Dehghani, E. Black, Z. Zhao, N. Haridas, S. Saha, D. Splan, M. Szczypka","doi":"10.1016/j.jcyt.2024.03.164","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.164","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141231305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HARNESSING POTENT NAÏVE LIKE T CELLS FOR PRECISION CAR T MANUFACTURING 利用强效天真类 t 细胞制造精准汽车 t
Cytotherapy Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.259
A. Jain, K. Amses, M. Markovska, K.M. Haines, M. Gohil, E. Pequignot, K. Sporici, Y. Uhera, H. Trivedi, A. L. Brennan, G. Plesa, R. Young, C. June, S.A. Sherrill-Mix, J.K. Everett, D. Siegel, F.D. Bushman, J.A. Fraietta, E.W. Weber, M.M. Davis
{"title":"HARNESSING POTENT NAÏVE LIKE T CELLS FOR PRECISION CAR T MANUFACTURING","authors":"A. Jain, K. Amses, M. Markovska, K.M. Haines, M. Gohil, E. Pequignot, K. Sporici, Y. Uhera, H. Trivedi, A. L. Brennan, G. Plesa, R. Young, C. June, S.A. Sherrill-Mix, J.K. Everett, D. Siegel, F.D. Bushman, J.A. Fraietta, E.W. Weber, M.M. Davis","doi":"10.1016/j.jcyt.2024.03.259","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.259","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141232040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A NOVEL NETWORK OF CELL PROCESSING AND CRYOPRESERVATION HUBS ADDRESSING CRITICAL GAPS IN CLINICAL SAMPLE PROCESSING CAPABILITIES FOR PHARMACEUTICAL COMPANIES AND CLINICAL TRIAL SPONSORS 细胞处理和低温保存中心的新型网络，弥补制药公司和临床试验申办者在临床样本处理能力方面的重大差距
Cytotherapy Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.238
S. Alter, A. Larson, P. Baraniak
{"title":"A NOVEL NETWORK OF CELL PROCESSING AND CRYOPRESERVATION HUBS ADDRESSING CRITICAL GAPS IN CLINICAL SAMPLE PROCESSING CAPABILITIES FOR PHARMACEUTICAL COMPANIES AND CLINICAL TRIAL SPONSORS","authors":"S. Alter, A. Larson, P. Baraniak","doi":"10.1016/j.jcyt.2024.03.238","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.238","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141232352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SCALABLE MANUFACTURING OF CAR-T CELLS USING A NON-VIRAL APPROACH AND A TRANSPOSON-TRANSPOSASE SYSTEM 利用非病毒方法和转座子-转座酶系统大规模制造 car-t 细胞
Cytotherapy Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.390
P. S. Couto, D. Stibbs, P. Springuel, Q.A. Rafiq
{"title":"SCALABLE MANUFACTURING OF CAR-T CELLS USING A NON-VIRAL APPROACH AND A TRANSPOSON-TRANSPOSASE SYSTEM","authors":"P. S. Couto, D. Stibbs, P. Springuel, Q.A. Rafiq","doi":"10.1016/j.jcyt.2024.03.390","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.390","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141232747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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