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A NOVEL NETWORK OF CELL PROCESSING AND CRYOPRESERVATION HUBS ADDRESSING CRITICAL GAPS IN CLINICAL SAMPLE PROCESSING CAPABILITIES FOR PHARMACEUTICAL COMPANIES AND CLINICAL TRIAL SPONSORS 细胞处理和低温保存中心的新型网络，弥补制药公司和临床试验申办者在临床样本处理能力方面的重大差距
Cytotherapy Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.238
S. Alter, A. Larson, P. Baraniak
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引用次数: 0
SCALABLE MANUFACTURING OF CAR-T CELLS USING A NON-VIRAL APPROACH AND A TRANSPOSON-TRANSPOSASE SYSTEM 利用非病毒方法和转座子-转座酶系统大规模制造 car-t 细胞
Cytotherapy Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.390
P. S. Couto, D. Stibbs, P. Springuel, Q.A. Rafiq
{"title":"SCALABLE MANUFACTURING OF CAR-T CELLS USING A NON-VIRAL APPROACH AND A TRANSPOSON-TRANSPOSASE SYSTEM","authors":"P. S. Couto, D. Stibbs, P. Springuel, Q.A. Rafiq","doi":"10.1016/j.jcyt.2024.03.390","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.390","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":"44 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141232747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
LONG-TERM DURABLE RESPONSES IN PATIENTS (PTS) WITH RELAPSED/REFRACTORY (R/R) ACUTE LYMPHOBLASTIC LEUKEMIA (ALL), DIFFUSE LARGE B-CELL LYMPHOMA (DLBCL), AND FOLLICULAR LYMPHOMA (FL) TREATED WITH TISAGENLECLEUCEL (TISA-CEL) AND ITS ASSOCIATION WITH PERSISTENCE OF CHIMERIC ANTIGEN RECEPTOR (CAR) T CELL 急性淋巴细胞白血病（all）、弥漫性大 B 细胞淋巴瘤（dlbcl）和滤泡性淋巴瘤（fl）复发/难治性（r/r）患者（pts）接受替沙根白细胞介素（tisagenlecleucel，tisa-cel）治疗后的长期持久反应及其与嵌合抗原受体（car）t 细胞持续存在的关系
Cytotherapy Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.297
R. Awasthi, E. Waldron, S.A. Grupp, M. A. Pulsipher, P. Bader, S. J. Schuster, R. Maziarz, E. Waller, U. Jager, C. Thieblemont, M. Dreyling, N. Fowler, H. J. Maier, J. Willert
{"title":"LONG-TERM DURABLE RESPONSES IN PATIENTS (PTS) WITH RELAPSED/REFRACTORY (R/R) ACUTE LYMPHOBLASTIC LEUKEMIA (ALL), DIFFUSE LARGE B-CELL LYMPHOMA (DLBCL), AND FOLLICULAR LYMPHOMA (FL) TREATED WITH TISAGENLECLEUCEL (TISA-CEL) AND ITS ASSOCIATION WITH PERSISTENCE OF CHIMERIC ANTIGEN RECEPTOR (CAR) T CELL","authors":"R. Awasthi, E. Waldron, S.A. Grupp, M. A. Pulsipher, P. Bader, S. J. Schuster, R. Maziarz, E. Waller, U. Jager, C. Thieblemont, M. Dreyling, N. Fowler, H. J. Maier, J. Willert","doi":"10.1016/j.jcyt.2024.03.297","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.297","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":"24 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141233369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
VARIATION IN EXTRACELLULAR VESICLES AMONG CLONAL AND POLYCLONAL MESENCHYMAL STROMAL CELL POPULATIONS – AN EXPANDED ANALYSIS 细胞外囊泡在克隆和多克隆间充质基质细胞群中的变化--扩展分析
Cytotherapy Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.157
E. Carson, T. Bonfield, V. Krishna, R. Midura, M. Swamydas, G. Duginski, P. Narayanan, S. Ranga, A. Furyes, S. Sandhir, G.F. Muschler
{"title":"VARIATION IN EXTRACELLULAR VESICLES AMONG CLONAL AND POLYCLONAL MESENCHYMAL STROMAL CELL POPULATIONS – AN EXPANDED ANALYSIS","authors":"E. Carson, T. Bonfield, V. Krishna, R. Midura, M. Swamydas, G. Duginski, P. Narayanan, S. Ranga, A. Furyes, S. Sandhir, G.F. Muschler","doi":"10.1016/j.jcyt.2024.03.157","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.157","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":"25 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141233492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HERMETICALLY SEALED CYCLIC OLEFIN POLYMER VIAL SYSTEMS AS AN ALTERNATE PRIMARY CONTAINER FOR CELL THERAPY 密封的环烯烃聚合物小瓶系统作为细胞疗法的替代主要容器
Cytotherapy Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.243
R. Li, D.B. Bhuiyan, K. Khan, M. Rase, H. Nguyen, O. Laskina, V. Murthy, V. Bhatnagar
{"title":"HERMETICALLY SEALED CYCLIC OLEFIN POLYMER VIAL SYSTEMS AS AN ALTERNATE PRIMARY CONTAINER FOR CELL THERAPY","authors":"R. Li, D.B. Bhuiyan, K. Khan, M. Rase, H. Nguyen, O. Laskina, V. Murthy, V. Bhatnagar","doi":"10.1016/j.jcyt.2024.03.243","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.243","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141233685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
REPRODUCIBLE DIFFERENTIATION OF IPSC TO NPC USING A CHEMICALLY DEFINED SCAFFOLD 利用化学定义的支架实现 IPSC 向 NPC 的可重现分化
Cytotherapy Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.462
S. Haneda, Y. Nakamura, T. Yanagisawa, R. Sanghavi
{"title":"REPRODUCIBLE DIFFERENTIATION OF IPSC TO NPC USING A CHEMICALLY DEFINED SCAFFOLD","authors":"S. Haneda, Y. Nakamura, T. Yanagisawa, R. Sanghavi","doi":"10.1016/j.jcyt.2024.03.462","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.462","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141233532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MANUFACTURE OF LENTIVIRAL VECTORS USING SUSPENSION SEMI-STABLE AND STABLE CELL LINES YIELDS TITRES COMPARABLE TO TRANSIENT PROCESS 使用悬浮半稳定和稳定细胞系制造慢病毒载体，可获得与瞬时过程相当的滴度
Cytotherapy Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.373
M. Tridgett, S. P. Johny, M. Raghunath, R. Parker-Manuel, C. Branciaroli, D. Yi, M. Li, P. Zhou, W. Valenti, D. Chang, K. Meaney, Q. Liu, M.I. Patricio
{"title":"MANUFACTURE OF LENTIVIRAL VECTORS USING SUSPENSION SEMI-STABLE AND STABLE CELL LINES YIELDS TITRES COMPARABLE TO TRANSIENT PROCESS","authors":"M. Tridgett, S. P. Johny, M. Raghunath, R. Parker-Manuel, C. Branciaroli, D. Yi, M. Li, P. Zhou, W. Valenti, D. Chang, K. Meaney, Q. Liu, M.I. Patricio","doi":"10.1016/j.jcyt.2024.03.373","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.373","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":"19 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141234044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
T2EVOLVE: STANDARDIZATION OF PRE-CLINICAL AND CLINICAL DEVELOPMENT OF ENGINEERED T CELL THERAPY IN EUROPE; A CROSS FUNCTIONAL MULTI STAKEHOLDER INITIATIVE T2EVOLVE：欧洲工程 T 细胞疗法临床前和临床开发的标准化；跨职能多方利益相关者倡议
Cytotherapy Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.223
M. Luu, C. Sanges, C. Dreuillet, E. Pennings, M. Casucci, P. Franz, E. Donnadieu, C. Quintarelli, S. Guedan, M. Kersten, E. Morris, Z. Ivics, U. Jager, D.H. Busch, E. Gonzalez, B. Paiva, B. Schröder, L. Chu, Y. Cabrizo, D. Ammar, S. Junius, U. Philippar, A. Fleischer, J. Awigena-Cook, I. Schapitz, D. Henderson, A. Kremer, S. Wagers, R. Choudhary, M. Hudecek
{"title":"T2EVOLVE: STANDARDIZATION OF PRE-CLINICAL AND CLINICAL DEVELOPMENT OF ENGINEERED T CELL THERAPY IN EUROPE; A CROSS FUNCTIONAL MULTI STAKEHOLDER INITIATIVE","authors":"M. Luu, C. Sanges, C. Dreuillet, E. Pennings, M. Casucci, P. Franz, E. Donnadieu, C. Quintarelli, S. Guedan, M. Kersten, E. Morris, Z. Ivics, U. Jager, D.H. Busch, E. Gonzalez, B. Paiva, B. Schröder, L. Chu, Y. Cabrizo, D. Ammar, S. Junius, U. Philippar, A. Fleischer, J. Awigena-Cook, I. Schapitz, D. Henderson, A. Kremer, S. Wagers, R. Choudhary, M. Hudecek","doi":"10.1016/j.jcyt.2024.03.223","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.223","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":"30 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141234796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HARNESSING THE POWER OF MULTIOMICS FROM FRESH AND FIXED PATIENT SAMPLE CHARACTERIZATION 从新鲜和固定患者样本特征中利用多组学的力量
Cytotherapy Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.434
A. O’Hara, Y. Han, Y. Fan, D. Corney, C. Mozdzierz, H. Latif, G. Zhou
{"title":"HARNESSING THE POWER OF MULTIOMICS FROM FRESH AND FIXED PATIENT SAMPLE CHARACTERIZATION","authors":"A. O’Hara, Y. Han, Y. Fan, D. Corney, C. Mozdzierz, H. Latif, G. Zhou","doi":"10.1016/j.jcyt.2024.03.434","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.434","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":"24 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141234941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CELL ENCAPSULATION AS A TOOL FOR STEM CELL BASED CELL THERAPY INDUSTRIALIZATION 细胞封装作为干细胞基础细胞疗法产业化的工具
Cytotherapy Pub Date : 2024-06-01 DOI: 10.1016/j.jcyt.2024.03.449
K. Alessandri, A. jana, P. nassoy, M. Feyeux, M. L. Fidalgo, B. Gurchenkov, A. Leonard, E. Luquet, F. Moncaubeig, C. rieu
{"title":"CELL ENCAPSULATION AS A TOOL FOR STEM CELL BASED CELL THERAPY INDUSTRIALIZATION","authors":"K. Alessandri, A. jana, P. nassoy, M. Feyeux, M. L. Fidalgo, B. Gurchenkov, A. Leonard, E. Luquet, F. Moncaubeig, C. rieu","doi":"10.1016/j.jcyt.2024.03.449","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.449","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":"25 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141235756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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