Epileptic DisordersPub Date : 2024-03-27DOI: 10.1684/j.1950-6945.1999.tb00312.x
{"title":"Policy for developing and publishing supplements or monographic themes","authors":"","doi":"10.1684/j.1950-6945.1999.tb00312.x","DOIUrl":"https://doi.org/10.1684/j.1950-6945.1999.tb00312.x","url":null,"abstract":"Approval to publish a suppplement to <jats:italic>Epileptic Disorders</jats:italic> or a monograph, special issue or book under the label <jats:italic>Epileptic Disorders</jats:italic> series must be obtained from the Supplement and/or Book Editors. Acceptance is not guaranteed. The final decision to publish a supplement or monograph will be based on the quality of the manuscripts and the topic covered. Proceedings of meetings, workshops, or congresses may be published as supplements. Epilepsy educational material may be published as monographs, books or edited as video cassettes or CD‐ROM's labeled <jats:italic>Epileptic Disorders series.</jats:italic>","PeriodicalId":50508,"journal":{"name":"Epileptic Disorders","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140312888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
An Qi Xu, Nicolas Nguyen, Elie Bou Assi, Dang Khoa Nguyen
{"title":"Stimulating the cingulate to move","authors":"An Qi Xu, Nicolas Nguyen, Elie Bou Assi, Dang Khoa Nguyen","doi":"10.1002/epd2.20219","DOIUrl":"10.1002/epd2.20219","url":null,"abstract":"<p>Locomotion is a goal-oriented behavior divided into three components: initiation (volitional or emotional), rhythmic limb movements, and intentional adjustment.<span><sup>1</sup></span> Volitional initiation involves the frontal cortex and thalamus, guided by an individual's intention to move<span><sup>2-4</sup></span>. Emotional initiation is directed by the cingulate cortex and insula, leading to a sensation of urge to move. After initiation of the locomotion, rhythmic limb movements are coordinated by central pattern generators in the brainstem, spinal cord, and cerebellum.<span><sup>4</sup></span> Our patient, a 45-year-old male who underwent an intracranial EEG study for left frontal lobe epilepsy, electrical stimulation of the anterior midcingulate cortex at 6 mA for 5 seconds repeatedly induced an “urge to move” and initiated a “getting-up” motion (Video 1), similar to the findings of Jackson et al.<span><sup>1</sup></span> and Caruana et al.<span><sup>5</sup></span></p>","PeriodicalId":50508,"journal":{"name":"Epileptic Disorders","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/epd2.20219","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140295173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Epileptic DisordersPub Date : 2024-03-27DOI: 10.1684/j.1950-6945.2000.tb00365.x
Jean Régis, Fabrice Bartolomei, Motohiro Hayashi, David Roberts, Patrick Chauvel, Jean‐Claude Peragut
{"title":"The role of gamma knife surgery in the treatment of severe epilepsies","authors":"Jean Régis, Fabrice Bartolomei, Motohiro Hayashi, David Roberts, Patrick Chauvel, Jean‐Claude Peragut","doi":"10.1684/j.1950-6945.2000.tb00365.x","DOIUrl":"https://doi.org/10.1684/j.1950-6945.2000.tb00365.x","url":null,"abstract":"There is a strong rationale for investigation of the role of gamma knife radiosurgery in the treatment of medically intractable epilepsy. To explore this potential application, the current outcome and morbidity associated with established microsurgical treatment, as well as the associated advantages and disadvantages of open surgery, are reviewed. The preliminary evidence in support of radiosurgical treatment and the recent experience with gamma knife treatment for epilepsy associated with mesial temporal sclerosis, cavernous angioma, and hypothalamic hamartoma or other lesions are presented. The strengths and limitations of this application are discussed, and the challenges facing both microsurgical and radiosurgical approaches are considered. Gamma knife surgery can be a main approach among others in the armamentarium of epilepsy surgery. Although the benefits of comfort and reduced invasivity can be clearly perceived, larger series and long‐term follow up are still required in order to evaluate the future of this particular surgical approach.","PeriodicalId":50508,"journal":{"name":"Epileptic Disorders","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140312984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Epileptic DisordersPub Date : 2024-03-27DOI: 10.1684/j.1950-6945.2000.tb00347.x
Thierry Deonna, Anne‐Lise Ziegler
{"title":"Hypothalamic hamartoma, precocious puberty and gelastic seizures: A special model of “epileptic” developmental disorder","authors":"Thierry Deonna, Anne‐Lise Ziegler","doi":"10.1684/j.1950-6945.2000.tb00347.x","DOIUrl":"https://doi.org/10.1684/j.1950-6945.2000.tb00347.x","url":null,"abstract":"Based on a review of the litterature and a detailed longitudinal single case study of a child with early onset gelastic seizures and hypothalamic hamartoma, the authors review the arguments suggesting that the acquired cognitive and behavioral symptoms seen in the majority of cases of this special epileptic syndrome result from a direct effect of the seizures. The early neurobehavioral profile of the case presented in this paper and that of a previous study is particular and combines features of a pervasive developmental and an attention deficit disorder which are probably closely related to the particular location of the epilepsy and its spread from the hypothalamus.","PeriodicalId":50508,"journal":{"name":"Epileptic Disorders","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140314092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Epileptic DisordersPub Date : 2024-03-27DOI: 10.1684/j.1950-6945.2000.tb00357.x
Cesare T. Lombroso
{"title":"Reply to Dr Vercueil","authors":"Cesare T. Lombroso","doi":"10.1684/j.1950-6945.2000.tb00357.x","DOIUrl":"https://doi.org/10.1684/j.1950-6945.2000.tb00357.x","url":null,"abstract":"","PeriodicalId":50508,"journal":{"name":"Epileptic Disorders","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140313012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Epileptic DisordersPub Date : 2024-03-27DOI: 10.1684/j.1950-6945.2002.tb00434.x
Colin D. Ferrie, Michael Koutroumanidis, Shaun Rowlinson, Sue Sanders, C.P. Panayiotopoulos
{"title":"Atypical evolution of Panayiotopoulos syndrome: A case report","authors":"Colin D. Ferrie, Michael Koutroumanidis, Shaun Rowlinson, Sue Sanders, C.P. Panayiotopoulos","doi":"10.1684/j.1950-6945.2002.tb00434.x","DOIUrl":"https://doi.org/10.1684/j.1950-6945.2002.tb00434.x","url":null,"abstract":"Panayiotopoulos syndrome is a relatively common condition with susceptibility to early onset benign childhood seizures, which manifests primarily with autonomic and mainly emetic symptoms. It predominantly affects children of 3‐6 years of age (13% of those with one or more non‐febrile seizures). EEG shows great variability, with occipital, extra‐occipital spikes or brief generalised discharges alone or in combination; it may also be consistently normal. Occipital spikes do not occur in one third of children. Despite the high prevalence of autonomic status epilepticus, the prognosis of Panayiotopoulos syndrome is usually excellent. Remission usually occurs within 1‐2 years from onset, one third have a single seizure but 5‐10% may have more than 10 seizures or a more prolonged course. Atypical evolutions with absences, atonic seizures and intellectual deterioration are exceptional; only two cases have been previously reported. We present a girl who initially had a prolonged autonomic status epilepticus typical of Panayiotopoulos syndrome, followed by seizures, with concurrent symptoms of Rolandic epilepsy. She then had an atypical evolution with atypical absences, absence status epilepticus, atonic seizures and mild impairment of scholastic performance. The case emphasises the close links between Panayiotopoulos syndrome and Rolandic epilepsy, both of which probably represent different clinical phenotypes of a maturational‐related benign childhood seizure susceptibility syndrome [published with videosequences].","PeriodicalId":50508,"journal":{"name":"Epileptic Disorders","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140313185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed Taha, Douglas R. Nordli III, Shawn Kacker, Audrey Oetomo, Chalongchai Phitsanuwong, Douglas R. Nordli Jr
{"title":"Electroclinical features of myoclonic-tonic and spasm-tonic seizures in childhood","authors":"Mohamed Taha, Douglas R. Nordli III, Shawn Kacker, Audrey Oetomo, Chalongchai Phitsanuwong, Douglas R. Nordli Jr","doi":"10.1002/epd2.20213","DOIUrl":"10.1002/epd2.20213","url":null,"abstract":"<p>Myoclonic-tonic (MT) and spasm-tonic (ST) seizures represent distinctive features in late infantile epileptic encephalopathy (LIEE). This commentary aims to delineate the electroclinical characteristics of MT and ST seizures, setting them apart from other seizure types. Our analysis encompasses 211 ST and MT seizures observed in 31 patients diagnosed with LIEE, providing a comprehensive overview of video-EEG features and polygraphic signatures. In MT seizures, EEG findings reveal a high-voltage diffuse spike/polyspike and wave discharge, often succeeded by diffuse electrodecrements. The amplitude-integrated EEG (aEEG) signature is described as a “reversed checkmark.” Conversely, ST seizures exhibit EEG findings such as a vertex positive deflection after a slow-wave and relative electrodecrement, with intermixed epileptiform discharges. In comparison to MT seizures, polygraphic characteristics in ST seizures appear more distinct, featuring a brief rhomboid shape corresponding to the spasm, followed by a lengthier rectangular shape indicative of the tonic phase of the ST seizure. While the pathophysiology of ST and MT seizures remains inadequately understood, their concurrent occurrence and association with other seizure types (tonic, epileptic spasm, myoclonic) within the temporal context of LIEE and other epileptic encephalopathies prompt us to anticipate advancements in our understanding through future research. We hope that this study serves as a foundation for unraveling these complexities in the times to come.</p>","PeriodicalId":50508,"journal":{"name":"Epileptic Disorders","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/epd2.20213","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140295172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Epileptic DisordersPub Date : 2024-03-27DOI: 10.1684/j.1950-6945.2002.tb00481.x
D.G.A. Kasteleijn‐Nolst Trenité, A. Martins da Silva, S. Ricci, G. Rubboli, C.A. Tassinari, J. Lopes, M. Bettencourt, J. Oosting, J.P. Segers
{"title":"Video games are exciting: a European study of video game‐induced seizures and epilepsy","authors":"D.G.A. Kasteleijn‐Nolst Trenité, A. Martins da Silva, S. Ricci, G. Rubboli, C.A. Tassinari, J. Lopes, M. Bettencourt, J. Oosting, J.P. Segers","doi":"10.1684/j.1950-6945.2002.tb00481.x","DOIUrl":"https://doi.org/10.1684/j.1950-6945.2002.tb00481.x","url":null,"abstract":"Background Video game seizures have been reported in photosensitive and non‐photosensitive patients with epilepsy. The game Super Mario World, has led to many cases of first seizures. We examined whether this game was indeed more provocative than other programs and whether playing the game added to this effect. Methods We prospectively investigated 352 patients in four European cities, using a standard protocol including testing of a variety of visual stimuli. We correlated historical data on provocative factors in daily life with electroencephalographic laboratory findings. Results The video game, Super Mario World proved more epileptogenic than standard TV programs and as provocative as programs with flashing lights and patterns. Most striking was the fact that video game‐viewing and‐playing on the 50 and 100 Hz TV was significantly more provocative than viewing the standard program ( <jats:italic>P</jats:italic> < 0.001, <jats:italic>P</jats:italic> < 0.05 respectively). Playing the video game Mario World on a 50 Hz TV, appeared to be significantly more provocative than playing this game on the 100 Hz TV ( <jats:italic>P</jats:italic> < 0.001). Of 163 patients with a history of TV‐, VG‐ or CG‐seizures, 85% of them showed epileptiform discharges in response to photic stimulation, 44% to patterns, 59% to 50 Hz TV and 29% to 100 Hz TV. Conclusions Children and adolescents with a history of video game seizures are, in the vast majority, photosensitive and should be investigated with standardised photic stimulation. Games and programs with bright background or flashing images are specifically provocative. Playing a video game on a 100 Hz TV is less provocative [published with videosequences].","PeriodicalId":50508,"journal":{"name":"Epileptic Disorders","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140312960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}