C A Tsiridis, V Holeva, N K Fountoulakis, V Potoupni, I Diakogiannis
{"title":"Cannabis use in a sample of Aristotle University of Thessaloniki students: a pilot cross-sectional study.","authors":"C A Tsiridis, V Holeva, N K Fountoulakis, V Potoupni, I Diakogiannis","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Cannabis is the most widespread illicit drug among young adults globally. This study aimed to detect the extent of cannabis use in the study population and its impact on users' lives. We hypothesized that early cannabis use would significantly predict later high-risk use.</p><p><strong>Methods: </strong>An online cross-sectional study using a self-administered questionnaire was conducted in December 2021, aiming to explore the extent of cannabis use among students and detect changes in behavior and impact on their lives. The results were analyzed statistically and correlated.</p><p><strong>Results: </strong>Out of the 297 enrolled participants with a mean age of 21.0 ± 2.1 years, 101 (33.9 %) had used cannabis at least once (50 males). The mean age at first cannabis use was 18.5 ± 2.11 years. Over 90 % reported easy access to it. Behavioral changes following use were reported by 41.6 %, but none except one sought help. Age at first cannabis use was negatively correlated with past-month and past-year use. Cannabis use before midday was positively correlated with age on the first try.</p><p><strong>Discussion: </strong>The prevalence of cannabis use was higher than the European average. Confirming the study's hypothesis, the younger the age at first use, the heavier the past-year and past-month use, which also agrees with previous studies. Cannabis consumption before noon was linked to increased use, and alarmingly, there was reluctance to seek help despite a high proportion of behavioral changes after use.</p><p><strong>Conclusion: </strong>As the legislation on the use of cannabis changes rapidly, and given the increasing popularity of cannabis, there is a need for continued research on how various factors differentially impact its use. HIPPOKRATIA 2021, 25 (4):162-168.</p>","PeriodicalId":50405,"journal":{"name":"Hippokratia","volume":"25 4","pages":"162-168"},"PeriodicalIF":0.6,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894300/pdf/hippokratia-25-162.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10654127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E Giza, M Lefkopoulou, D Dimitrakopoulos, S Karachristianou, C Liasidis
{"title":"The impact of the Covid-19 pandemic on a Greek cohort of patients with epilepsy.","authors":"E Giza, M Lefkopoulou, D Dimitrakopoulos, S Karachristianou, C Liasidis","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The Covid-19 pandemic, the subsequent lockdown, and the measures of social distancing may have had adverse effects on patients with epilepsy (PWE). This study was designed to assess the pandemic's psychological impact on the Greek non-infected PWE and possible changes in their seizure control.</p><p><strong>Method: </strong>The patients were evaluated utilizing a semi-structured interview consisting of open questions regarding their demographic, social, and clinical characteristics, followed by five questions (on a scale of 0-10) related to the Covid-19 pandemic, lockdown, and social distancing measures. Anxiety and depression of PWE were screened using the Hospital Anxiety and Depression Scale (HADS), which consists of HADS-Anxiety and HADS-Depression subscales.</p><p><strong>Results: </strong>We evaluated 65 PWE in the outpatient clinic (60 %) or via telephone interview (40 %). None of these patients experienced changes in seizure control. The mean scores of the Covid-19-related questions were 6.1 ± 2.7 (fear of getting infected), 4.7 ± 3.3 (fear of death), 7.1 ± 2.7 (fear of sickness for their relatives), 6.4 ± 3.1 (stress during lockdown), and 3.0 ± 2.9 (fear of antiepileptic drugs unavailability). Thirty-nine (60 %) patients screened positive for anxiety and thirty-three (50.8 %) for depression.</p><p><strong>Conclusion: </strong>The psychological impact of the Covid-19 pandemic, lockdown, and social distancing measures on non-infected PWE was moderate without changes in their seizure control. HIPPOKRATIA 2021, 25 (4):145-150.</p>","PeriodicalId":50405,"journal":{"name":"Hippokratia","volume":"25 4","pages":"145-150"},"PeriodicalIF":0.6,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894308/pdf/hippokratia-25-145.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10654124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Charles Bonnet syndrome: a case report of black and white visual hallucinations.","authors":"C C Liapis, A C Spyropoulou, A Pehlivanidis","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50405,"journal":{"name":"Hippokratia","volume":"25 4","pages":"177-178"},"PeriodicalIF":0.6,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894301/pdf/hippokratia-25-177.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10663267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G Michos, A Sotiriadis, E Paraskevaidis, I Georgiou, T Dagklis, A Mamopoulos, E Papanikolaou, A Athanasiadis, G Makrydimas
{"title":"Is nuchal translucency measurement feasible in early pregnancy?","authors":"G Michos, A Sotiriadis, E Paraskevaidis, I Georgiou, T Dagklis, A Mamopoulos, E Papanikolaou, A Athanasiadis, G Makrydimas","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>To investigate whether early nuchal translucency measurement at 7<sup>+0</sup> to 9<sup>+0</sup> weeks (NT<sub>7-9w</sub>) is feasible, obtain normal values for different crown-rump lengths (CRL) in the above weeks and create percentile tables.</p><p><strong>Methods: </strong>A prospective study was conducted in the Obstetrics and Gynecology Department of the University Hospital of Ioannina, including data from women with singleton pregnancies, examined in the early pregnancy unit between November 2010 and May 2015 at a CRL of 10-27 mm. The early pregnancy scan was performed vaginally, and the NT<sub>7-9w</sub>, CRL, fetal heart rate, and mean yolk sac diameter were measured. Demographic data, including body mass index and smoking, were recorded.</p><p><strong>Results: </strong>NT<sub>7-9w</sub> was measured successfully in 192 fetuses out of 210 (91.4 %), with a CRL ranging from 10-27 mm. The median maternal age was 31 (range 18-43) years, and the median CRL was 19.9 (range 10.0-27.0) mm. Considering the above measurements, we created normal values and percentiles tables of NT at 7<sup>+0</sup> to 9<sup>+0</sup> weeks in relation to the corresponding CRL measurement.</p><p><strong>Conclusion: </strong>According to the literature, this is the first attempt to measure NT in such weeks of pregnancy. NT measurement as early as 7<sup>+0</sup> to 9<sup>+0</sup> is feasible and normal values can be created and correlated with CRL measurements. HIPPOKRATIA 2021, 25 (4):151-155.</p>","PeriodicalId":50405,"journal":{"name":"Hippokratia","volume":"25 4","pages":"151-155"},"PeriodicalIF":0.6,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894305/pdf/hippokratia-25-151.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10654130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Implantable cardioverter-defibrillator troubleshooting diagnosis with the contribution of an electrocardiogram.","authors":"E Sdogkos, I Vogiatzis","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50405,"journal":{"name":"Hippokratia","volume":"25 4","pages":"179-180"},"PeriodicalIF":0.6,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894307/pdf/hippokratia-25-179.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10654126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I Tsakiridis, I Kalogiannidis, A Mamopoulos, T Dagklis, Ch Nikolaidou, A Athanasiadis
{"title":"Giant uterine STUMP in pregnancy: A rare case report with preservation of fertility.","authors":"I Tsakiridis, I Kalogiannidis, A Mamopoulos, T Dagklis, Ch Nikolaidou, A Athanasiadis","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Smooth muscle tumors of uncertain malignant potential (STUMPs) are infrequent and represent an extremely rare cause of oligohydramnios in pregnant women.</p><p><strong>Description of the case: </strong>A 34-year-old woman at 25 weeks of gestation was referred with clinical features indicative of anemia. The transabdominal ultrasound revealed a fetus with appropriate growth for the gestational age, with oligohydramnios and a giant uterine mass. At 30 weeks of gestation, due to anhydramnios and repeated non-reassuring non-stress tests, a cesarean section was performed, followed by a myomectomy of a 9 kg mass. A neonate weighing 1,350 g was delivered (Apgar score 1΄: 4, 5΄: 7). The woman preserved her fertility and had an uneventful recovery during the puerperium, while the final histology revealed multiple STUMPs. The postoperative management included follow-up every six months for five years.</p><p><strong>Conclusion: </strong>This is the only reported case of a pregnant woman with STUMPs of this size that underwent myomectomy during the cesarean section and avoided hysterectomy. HIPPOKRATIA 2021, 25 (4):169-171.</p>","PeriodicalId":50405,"journal":{"name":"Hippokratia","volume":"25 4","pages":"169-171"},"PeriodicalIF":0.6,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894306/pdf/hippokratia-25-169.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10654123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G A Paspatis, P Nikolaou, M Velegraki, A Mpitouli, M Fragaki
{"title":"The use of endocuff for the facilitation of endoscopic mucosal resection in defiant colonic polyps. A case series.","authors":"G A Paspatis, P Nikolaou, M Velegraki, A Mpitouli, M Fragaki","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Endocuff has been suggested as a safe and useful device facilitating complex endoscopic mucosal resection (EMR) in the sigmoid colon; however, the existing data are sparse. In this case series, we report our experience with endocuff in facilitating EMR in defiant polyps throughout the colon.</p><p><strong>Case series: </strong>In colonoscopies where sufficient stability and, thus, reliable visualization of the lesion was not possible (defiant polyp), the endoscope was removed, and subsequently, an ENDOCUFF VISION<sup>TM</sup> was mounted on its tip. Thereafter, the colonic area of interest underwent endoscopic re-examination. The study prospectively included fifteen patients with 16 sessile/flat polyps. Fifteen of the 16 EMRs were considered successful.</p><p><strong>Conclusions: </strong>This case series indicates the use of endocuff as an auxiliary device for facilitating EMR in defiant colonic polyps. HIPPOKRATIA 2021, 25 (3):134-137.</p>","PeriodicalId":50405,"journal":{"name":"Hippokratia","volume":"25 3","pages":"134-137"},"PeriodicalIF":0.6,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851142/pdf/hippokratia-25-134.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9131387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O Yalav, S Gumus, M O Gul, I C Eray, A Rencuzogullari
{"title":"Gastric gastrointestinal stromal tumors. Is there a necessity to use imatinib in the intermediate-risk group?","authors":"O Yalav, S Gumus, M O Gul, I C Eray, A Rencuzogullari","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>A gastrointestinal stromal tumor (GIST) is a tumor that occurs in the gastrointestinal tract, most frequently in the stomach or small intestine. This study aimed to reveal the clinical, histopathological, and immunohistochemical features of patients with GIST and to determine the effect of adjuvant tyrosine kinase inhibitor (TKI) use on survival rates in intermediate-risk gastric GIST cases.</p><p><strong>Methods: </strong>Clinical characteristics, histopathological findings, and oncological outcomes of 51 patients operated on for gastric GIST between 2010 and 2019 were analyzed retrospectively. Patients treated with neoadjuvant and adjuvant TKI were identified. The effect of adjuvant therapy on survival in the intermediate-risk group was examined.</p><p><strong>Results: </strong>There were 33 females and 18 males, with a mean age of 64.9 ± 12.8 years. The most common surgical procedure was gastric wedge resection. Three cases were treated with laparoscopy, and 48 underwent open surgery. A multi-visceral resection was carried out in three cases. All cases underwent R0 resection. In the intermediate-risk group, there were no statistical differences between individuals receiving adjuvant therapy (n =12) and those not receiving adjuvant therapy (n =6) regarding survival rates (p =0.157). The average follow-up period was 54.9 (min: 2 - max: 106) months. Over this period, in three and five patients, recurrence and metastases occurred, respectively, and seven patients succumbed to the disease. Disease-free survival for five years was 93.7 %, metastasis-free survival was 83.4 %, and overall survival was 86.7 %. HIPPOKRATIA 2021, 25 (3):113-118.</p><p><strong>Conclusions: </strong>This study showed that adjuvant TKI therapy did not affect survival rates in intermediate-risk gastric GIST.</p>","PeriodicalId":50405,"journal":{"name":"Hippokratia","volume":"25 3","pages":"113-118"},"PeriodicalIF":0.6,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851140/pdf/hippokratia-25-113.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10635060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Arvaniti, P Steiropoulos, Ch Panousis, E Kalamara, M Samakouri, T Constantinidis, E Nena
{"title":"Sleep quality and associated factors in the context of COVID-19, among prehospital emergency personnel, in North-Eastern Greece.","authors":"A Arvaniti, P Steiropoulos, Ch Panousis, E Kalamara, M Samakouri, T Constantinidis, E Nena","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The stressful conditions that emerged during the Coronavirus disease 2019 (COVID-19) pandemic have had a negative impact on sleep quality in large part of the healthcare worker population. This study aimed to assess the self-reported quality of sleep among members of the Emergency Ambulance Service personnel of the National Emergency Center in the region of Thrace, Northeastern Greece, and to investigate its associations with perceived stress, feelings, and perceptions of well-being during the COVID-19 pandemic.</p><p><strong>Methods: </strong>The study was conducted from March to May 2021 using an online structured questionnaire, and the collected data included: socio-demographic characteristics, occupational and medical history, distress and mental health issues due to COVID-19 and the following self-administrated instruments: Pittsburgh Sleep Quality Index (PSQI), WHO-5 Well-Being Index (WHO-5), and Perceived Stress Scale-14 items (PSS-14).</p><p><strong>Results: </strong>Among the 74 participants, 71 % were poor sleepers (i.e., PSQI >5). The majority (83 % of the sample) reported feelings of stigma due to their occupation, with the proportion being higher among women (100 % vs 78 % in men, p =0.05) and poor sleepers (95 % vs 65 % in good sleepers, p =0.03). Poor sleepers had significantly lower WHO-5 scores than good sleepers (13.8 ± 4.9 vs 16.9 ± 5.8, p =0.04) and were experiencing significantly more anxiety and/or sadness at the time they answered the questionnaire (69.1 % vs 35.3 %, p =0.02). Perceived stress was significantly positively correlated with the \"Latency\" dimension of the PSQI (p =0.03).</p><p><strong>Conclusions: </strong>Poor sleep quality and feelings of stigmatization were prevalent for most of the sample. Poor sleep quality was associated more frequently with reported feelings of stigmatization, anxiety and/or sadness, and impaired well-being. HIPPOKRATIA 2021, 25 (3):126-133.</p>","PeriodicalId":50405,"journal":{"name":"Hippokratia","volume":"25 3","pages":"126-133"},"PeriodicalIF":0.6,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851136/pdf/hippokratia-25-126.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9131385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}