Yaridé Pérez-Pacheco, Tiziano Alimandi, B. Tylkowski, M. Sisteré, R. García-Valls
{"title":"Chitosan-TPP microcapsules for controlled drug release","authors":"Yaridé Pérez-Pacheco, Tiziano Alimandi, B. Tylkowski, M. Sisteré, R. García-Valls","doi":"10.55815/424214","DOIUrl":"https://doi.org/10.55815/424214","url":null,"abstract":"Production of chitosan/sodium tripolyphosphate (CS/TPP) microcapsules via spray drying involves atomizing an emulsion containing CS, TPP, acetic acid (AcOH), and folic acid (FA) into fine droplets exposed to high-temperature, low-pressure gas flow. Solvent evaporation within the drying chamber leads to solid particle formation. Spray drying is valuable for creating solid CS/TPP microcapsules. Precise equipment parameter adjustments, like inlet temperature and gas flow rate, enable the study of microcapsule morphology, size, and properties. This adaptability allows for customization to specific pH dissolution ranges. The production method's impact on CS/TPP microcapsules was studied by modifying spray drier parameters, including inlet temperature and aspirator pressure, to enhance understanding of their behavior in solution under varied production conditions. \u0000In chitosan delivery systems, various approaches can encapsulate drug agents like folic acid, an analog to the cancer treatment drug methotrexate. Agents can be added to the chitosan solution pre-crosslinking, incorporated into gelation-inducing agents pre-mixing with chitosan, or included in the crosslinking mixture. Experiments were conducted to assess CS/TPP microcapsules' behavior when encapsulating agents like folic acid. Release profiles were analyzed to understand their drug delivery capabilities and potential as controlled release carriers.","PeriodicalId":503916,"journal":{"name":"Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry","volume":"101 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140422600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francisco Amaro-Martinez, Qiang Cheng, R. Nomen, J. Sempere
{"title":"The Transition to Industry 4.0 in the Catalan Chemical Industry. Baseline 2020","authors":"Francisco Amaro-Martinez, Qiang Cheng, R. Nomen, J. Sempere","doi":"10.55815/426980","DOIUrl":"https://doi.org/10.55815/426980","url":null,"abstract":"The baseline for the state of implementation of Industry 4.0 technologies in the Catalan chemical industry in 2020 is established using the model proposed by the Industry 4.0 Commission of the Institution of Engineers of Catalonia. Two panels are convened, one comprising AIQS experts and the other industry executives. The responses from both panels exhibit similar trends. Among the levers used by the model, Inventory Control emerges as the most successfully implemented in the industry, followed by Cybersecurity, Production Planning, Monitoring and Control, and Environmental Efficiency. However, certain deficiencies are noted in the implementation of advanced maintenance practices. Industry executives generally express satisfaction with the current level of Industry 4.0 technology implementation. However, they exhibit lower satisfaction levels with levers such as Relationships with Suppliers, Data Collection, and Process Modelling. Anticipated impacts of Industry 4.0 technology implementation are expected to be highly favourable and desirable, particularly in the realm of manufacturing processes. Additionally, a projection of Industry 4.0 technology implementation with a horizon extending to 2025 is conducted, which will require comparison with future studies.","PeriodicalId":503916,"journal":{"name":"Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry","volume":"312 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140417900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Barozzi, Anita Barni, Luca Leopardi, Carlo Bottinelli, Jacopo Ghezzi, S. Copelli
{"title":"Investigation on dynamic VOC production from industrial, high solids content emulsion polymerizations","authors":"M. Barozzi, Anita Barni, Luca Leopardi, Carlo Bottinelli, Jacopo Ghezzi, S. Copelli","doi":"10.55815/424217","DOIUrl":"https://doi.org/10.55815/424217","url":null,"abstract":"Volatile Organic Compounds (VOC) pose a serious threat to human health and the environment. Unfortunately, many processes from fine chemistry involve VOCs as reagents, solvents, products or by-products. International standards and market requirements keep asking for lower VOC content in commercial goods, with the final aim of VOC-free products. Accomplishing such a task is a challenge because VOCs, due to their high vapour pressure, are hard to remove with traditional industrial methods, such as vacuum stripping or absorption. For this reason, it is important to know and understand how VOCs evolve throughout a chemical reaction. In this field, adhesives, which are usually developed exploiting polymerizations, represent an interesting subject, due to the complexity of their industrial synthesis: VOCs appear as reagents (monomers), conversion enhancers (post-polymerization), and by-products (hydrolysis and small chains). In this work, a study on the evolution and content of VOCs of an industrial recipe involving emulsion polymerizations is carried out. The industrial recipe is characterized by high solids content (about 70% w/w) and is mainly composed of 2-ethylhexyl acrylate (up to 50% w/w), anionic and nonionic surfactants. The evolution of the main VOCs found under different working conditions is discussed. The main VOCs found are acetaldehyde, acetone, t-butanol, vinyl acetate, butanol, methyl-methacrylate, butyl acrylate, 2-ethyl-exyl-alcohol, 2-ethyl-exyl-acetate and 2-ethyl-exyl-acrylate.","PeriodicalId":503916,"journal":{"name":"Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry","volume":"291 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140420928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of the NPK Method in the Crystallization Kinetics of High-Density Polyethylene","authors":"Frida Monzón, M. D. Rovira, J. Sempere, R. Nomen","doi":"10.55815/424211","DOIUrl":"https://doi.org/10.55815/424211","url":null,"abstract":"The Non-Parametric Kinetics (NPK) method, developed in 1998, by Serra, R., Sempere, J. and Nomen, R. has been used by them and other research groups to analyze the thermal behavior of a physical or chemical transformation and thermal stability. However, it was until 2021 that the method was applied for the first time in a cooling process for the determination of the crystallization kinetics of polypropylene, obtaining satisfactory results. \u0000The advantage of the NPK method is that it does not assume any model for the temperature function, nor for the conversion function to describe the crystallization kinetics. Through a mathematical process, the method provides two vectors: the vector u, which contains the information about the kinetic model, and the vector v, which contains the information about the temperature function. \u0000The aim of this work is to verify that the NPK method is applicable to the crystallization of high-density polyethylene by comparing the results with the most commonly used models to describe the crystallization kinetics of polymers. The fits obtained were very good and the vector u and v allow us to reproduce the original curves from DSC.","PeriodicalId":503916,"journal":{"name":"Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry","volume":"115 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140422246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cristina Mas-Peiró, Fèlix Llovell Ferret, Oriol Pou Ibar
{"title":"Computational Fluid Dynamic study of gas mixtures in a Non-Thermal Plasma reactor for CO2 conversion with Argon as diluent gas","authors":"Cristina Mas-Peiró, Fèlix Llovell Ferret, Oriol Pou Ibar","doi":"10.55815/424061","DOIUrl":"https://doi.org/10.55815/424061","url":null,"abstract":"CO2 utilization has been an emerging technology of increasing global interest due to its direct impact in limiting greenhouse gas emissions. In this contribution, the fluid dynamic behavior of a CO2 conversion non-thermal plasma (NTP) in a dielectric barrier discharge (DBD) reactor is studied through computational fluid dynamics (CFD) simulations. \u0000Calculations are provided in conjunction with experimental results and the thermodynamic characterization of the compounds and mixtures involved. This CFD study utilizes a well-established methodology that allows the optimization of fluid flow with limited computational burden. \u0000Firstly, results are presented for an Example Case, in which several variables are studied both at the final iteration as well as across iterations. Secondly, a range of Study Cases, changing the inlet composition and volume rate, are presented. Average velocity is one of the most significant variables to predict the reactor’s yield, while the temperature, density and pressure in the reactor remain, in most cases, almost constant. \u0000The resulting CFD computations describe the behavior of the fluids in the reactor in a predictive manner for future experimental results. Limitations in the fluid’s characterization occur due to not explicitly including the plasma reaction, which will be aimed at in future contributions.","PeriodicalId":503916,"journal":{"name":"Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry","volume":"50 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140418095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Corrosion Risk for Process Safety in the Chemical Industry","authors":"Alec Groysman","doi":"10.55815/424213","DOIUrl":"https://doi.org/10.55815/424213","url":null,"abstract":"The aim of this work is to analyze how corrosion risk management influences process safety. Both issues occupy an important niche in the chemical industry. Corrosion risk management includes identifying, analyzing, assessing, and managing corrosion hazards. Process safety is a discipline that focuses on preventing fires, explosions, and accidental releases at chemical process facilities. Corrosion can cause all these detrimental events. \u0000There is much literature about both topics, corrosion risk, and process safety, separately, but there are nearly no research works concerning intersection and influence. \u0000The level of corrosion failure and its consequences, defining corrosion risk, may be different: the leak of crude oil, natural gas, water, liquid and gaseous hazardous chemicals, fire, explosion, damages, deterioration of the environment, injuries, and death of people and animals. Due to the biological and psychological properties of human nature, we are unlikely to exclude human mistakes. \u0000We should pay significant attention to education, dissemination of information, knowledge transfer, collaboration, and communication. Correct corrosion risk management gives rise to the improvement of process safety at stages of design, fabrication, implementation, erection, service, and maintenance of equipment and constructions in the chemical industry. \u0000For this realization, specific corrosion mitigation strategies and technologies are described. They are successfully implemented in the chemical industry. It shows how corrosion management and process safety management can be better integrated into practice. \u0000The future consideration of the prognosis of corrosion risk with process safety is connected with corrosion modeling. Limitations and challenges of such a forecast are discussed too. \u0000Special educational and training programs are developed to help engineers, scientists, professionals, students, and managers learn about corrosion science and engineering","PeriodicalId":503916,"journal":{"name":"Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry","volume":"22 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140418457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antoni Sánchez, Nicolás Oiza, A. Artola, Xavier Font, R. Barrena, Javier Moral-Vico, T. Gea
{"title":"Solid-state fermentation: a review of its opportunities and challenges in the framework of circular bioeconomy","authors":"Antoni Sánchez, Nicolás Oiza, A. Artola, Xavier Font, R. Barrena, Javier Moral-Vico, T. Gea","doi":"10.55815/424209","DOIUrl":"https://doi.org/10.55815/424209","url":null,"abstract":"Solid-state fermentation (SSF) is on the way to become an attractive alternative for the valorisation of a wide range of organic waste. In biological terms, SSF can be defined as the cultivation process in which microorganisms grow on solid materials without the presence of free water. When these solid materials are organic waste and the objective is to produce one or several bioproducts of added value, SSF is a clear opportunity for circular bioeconomy, with a new paradigm “from waste to resource”. The development of SSF started a couple of decades ago, with biomolecules that only could be produced through biological systems, such as enzymes or antibiotics. However, a new generation of SSF bioproducts, which have a “twin” produced by chemical pathways, has emerged in the last years, with the advantages of having lower environmental impacts (for instance, no need of water and less energy requirements) and using waste as substrate. Some of these compounds are highly relevant in the field of chemical engineering: biosurfactants, biopesticides, aromas, bioplastics, pigments and bioflocculants, among others. This review explores the new advances in SSF: from the organic waste used as substrate to the main challenges SSF is facing, that is, mass and heat transfer limitations, bioproducts downstream and scale-up. \u0000 ","PeriodicalId":503916,"journal":{"name":"Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry","volume":"6 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140419600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana María Espinosa Negrín, Lisbet Mailín López González, Janet Jiménez Hernández
{"title":"Effect of pretreatment with efficient microorganisms on anaerobic digestion of rice drying residue","authors":"Ana María Espinosa Negrín, Lisbet Mailín López González, Janet Jiménez Hernández","doi":"10.55815/422397","DOIUrl":"https://doi.org/10.55815/422397","url":null,"abstract":"Rice drying generates large amounts of impurities which has been previously studied for biogas production with unfavorable results due to its high lignocellulosic content. This research aimed to assess the effect of the pretreatment and bioaugmentation with efficient microorganisms on the anaerobic digestion of rice drying residue, and the kinetics of methane production. For the study, rice drying residues were pretreated for 48 hours with efficient microorganisms diluted 1:100, in a relation of 18 mL gVS-1 of substrate; while for bioaugmentation microorganisms were added directly to the reactors. The kinetic behavior of the digestion process was described through four models of first and second order. The highest methane yield was obtained with pretreated residues (363.7 LN kgVS-1), being 9.9% higher than that of the substrate without pretreatment. Bioaugmentation did not show significant differences. All the models fitted well with the experimental cumulative methane yield data, but the Hill modified model had the best fit in all cases. The study shows that the use of efficient microorganisms is an attractive option to increase waste degradation in anaerobic digestion processes.","PeriodicalId":503916,"journal":{"name":"Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry","volume":"163 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139170394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasound-assisted transesterification of Moringa oleifera seed oil and the effect of operating conditions on biodiesel yield","authors":"Yosvany Díaz Domínguez, Marianela Ortiz-Álvarez, Indira Tobío-Pérez, S. Pohl, Ramón Piloto-Rodríguez","doi":"10.55815/422378","DOIUrl":"https://doi.org/10.55815/422378","url":null,"abstract":"Moringa oleifera seed oil represents a promising feedstock for biodiesel production due to its availability, oil content, and oil and biodiesel properties. Biodiesel production assisted by ultrasound high-frequency and low power is more sustainable and thus proves to be an alternative way to produce biodiesel. In this work, the effects of reaction time and amplitude on the M. oleifera oil transesterification process assisted by ultrasound were evaluated. The reaction was carried out using an ultrasonication device Hielscher Model UP200S operated at 200 W and a frequency of 24 kHz. The physicochemical properties of the Moringa oleifera oil were in close agreement with previous reports while the derivate methyl esters meet the ASTM D6751 and EN 14214 standards. At relatively short reaction times (5-30 min), the methyl esters yield ranged from 82.38 to 94.30 %. The results indicated that the best condition of design of experiments was achieved for 50 % of amplitude and 30 min of reaction time, obtaining the highest methyl ester yield (93.54 %). Moreover, it was also demonstrated that an increase in reaction time such as 45 min did not produce a significantly higher conversion of Moringa oleifera methyl esters.","PeriodicalId":503916,"journal":{"name":"Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry","volume":"272 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139170708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nadia Corpas-Rodríguez, Amaury Pérez-Sánchez, Jesús Antonio Córdova-López, Luis B. Ramos-Sánchez, María Caridad Julián-Ricardo
{"title":"Analysis of technological alternatives for microbial oil production","authors":"Nadia Corpas-Rodríguez, Amaury Pérez-Sánchez, Jesús Antonio Córdova-López, Luis B. Ramos-Sánchez, María Caridad Julián-Ricardo","doi":"10.55815/422390","DOIUrl":"https://doi.org/10.55815/422390","url":null,"abstract":"At present, lignocellulosic biomass and especially agro-industrial by-products have ceased to be considered solid residues, to become potential raw materials for various processes. In this sense, the present work aims to analyze technological alternatives for obtaining microbial oil in a pilot facility, through simulation in SuperPro Designer simulator, in order to implement a process that is technically, economically and environmentally efficient. Starting from a previous experimental work, where the best results for the cell growth stage were obtained at a C/N ratio of 100 and a fermentation time of 72 hours. The technological design of a base case of a plant for the production of microbial oil was based on the process designed by Vieira (2016) 1 and simulated as technological alternatives to obtain microbial oil by submerged fermentation (alternative 1) and solid-state fermentation (alternative 2). Technical, economic and environmental analyzes of each technological alternative were performed, obtaining the best results for alternative 2, in which a production of 614.9 liters of oil per year is obtained, a productivity of 2.66 g/Lh, and a unit cost of 224.25 €/L. In addition the filtered residues can be recycled, or can be used as a feedstock for animal feed production.","PeriodicalId":503916,"journal":{"name":"Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry","volume":"96 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139170920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}