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LARP7 Contributes to Glucose-Induced Cardiac Dysfunction, Apoptosis and Fibrosis by Inhibiting the Degradation of STING LARP7 通过抑制 STING 的降解促进葡萄糖诱导的心脏功能障碍、细胞凋亡和纤维化
Frontiers in Bioscience-Landmark Pub Date : 2024-07-26 DOI: 10.31083/j.fbl2907274
Jingjing Sun, Ziming Wang, Yixuan Duan, Chang Liu, Sihai Zhao, Jie Deng
{"title":"LARP7 Contributes to Glucose-Induced Cardiac Dysfunction, Apoptosis and Fibrosis by Inhibiting the Degradation of STING","authors":"Jingjing Sun, Ziming Wang, Yixuan Duan, Chang Liu, Sihai Zhao, Jie Deng","doi":"10.31083/j.fbl2907274","DOIUrl":"https://doi.org/10.31083/j.fbl2907274","url":null,"abstract":"","PeriodicalId":503756,"journal":{"name":"Frontiers in Bioscience-Landmark","volume":"14 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141800995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unraveling the Role of TP53 in Colorectal Cancer Therapy: From Wild-Type Regulation to Mutant 揭示 TP53 在结直肠癌治疗中的作用：从野生型调控到突变型调控
Frontiers in Bioscience-Landmark Pub Date : 2024-07-25 DOI: 10.31083/j.fbl2907272
Wenshu Li, Longyuan Li, Huan Yang, Chenxi Shi, Zhe Lei, Lingchuan Guo, Yuhong Wang
{"title":"Unraveling the Role of TP53 in Colorectal Cancer Therapy: From Wild-Type Regulation to Mutant","authors":"Wenshu Li, Longyuan Li, Huan Yang, Chenxi Shi, Zhe Lei, Lingchuan Guo, Yuhong Wang","doi":"10.31083/j.fbl2907272","DOIUrl":"https://doi.org/10.31083/j.fbl2907272","url":null,"abstract":"","PeriodicalId":503756,"journal":{"name":"Frontiers in Bioscience-Landmark","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141803410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Leonurine Ameliorates Diabetic Nephropathy through GPX4-Mediated Ferroptosis of Endothelial Cells 利奥那林通过 GPX4 介导的内皮细胞铁氧化作用改善糖尿病肾病
Frontiers in Bioscience-Landmark Pub Date : 2024-07-25 DOI: 10.31083/j.fbl2907270
Xinyuan Yu, Yuan Li, Yaoyuan Zhang, Kai Yin, Xu Chen, Xiao Zhu
{"title":"Leonurine Ameliorates Diabetic Nephropathy through GPX4-Mediated Ferroptosis of Endothelial Cells","authors":"Xinyuan Yu, Yuan Li, Yaoyuan Zhang, Kai Yin, Xu Chen, Xiao Zhu","doi":"10.31083/j.fbl2907270","DOIUrl":"https://doi.org/10.31083/j.fbl2907270","url":null,"abstract":"","PeriodicalId":503756,"journal":{"name":"Frontiers in Bioscience-Landmark","volume":"32 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141805270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Encephalomyocarditis Virus Structural Protein VP3 Interacts with MAVS and Promotes its Autophagic Degradation to Interfere with the Type I Interferon Signaling Pathway 脑脊髓炎病毒结构蛋白 VP3 与 MAVS 相互作用并促进其自噬降解，从而干扰 I 型干扰素信号通路
Frontiers in Bioscience-Landmark Pub Date : 2024-07-25 DOI: 10.31083/j.fbl2907273
Xu Zhao, Zhengyang Hou, Yaxin Zhang, Daoqin Mao, Zhenfang Yan, Shunyu Yang, Jingying Xie, Ruofei Feng
{"title":"Encephalomyocarditis Virus Structural Protein VP3 Interacts with MAVS and Promotes its Autophagic Degradation to Interfere with the Type I Interferon Signaling Pathway","authors":"Xu Zhao, Zhengyang Hou, Yaxin Zhang, Daoqin Mao, Zhenfang Yan, Shunyu Yang, Jingying Xie, Ruofei Feng","doi":"10.31083/j.fbl2907273","DOIUrl":"https://doi.org/10.31083/j.fbl2907273","url":null,"abstract":"","PeriodicalId":503756,"journal":{"name":"Frontiers in Bioscience-Landmark","volume":"30 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141806372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
miRNA Signatures in Bronchopulmonary Dysplasia: Implications for Biomarkers, Pathogenesis, and Therapeutic Options 支气管肺发育不良的 miRNA 信号：对生物标志物、发病机制和治疗方案的影响
Frontiers in Bioscience-Landmark Pub Date : 2024-07-25 DOI: 10.31083/j.fbl2907271
Hajime Maeda, Xiaoyun Li, Hayato Go, P. Dennery, H. Yao
{"title":"miRNA Signatures in Bronchopulmonary Dysplasia: Implications for Biomarkers, Pathogenesis, and Therapeutic Options","authors":"Hajime Maeda, Xiaoyun Li, Hayato Go, P. Dennery, H. Yao","doi":"10.31083/j.fbl2907271","DOIUrl":"https://doi.org/10.31083/j.fbl2907271","url":null,"abstract":"","PeriodicalId":503756,"journal":{"name":"Frontiers in Bioscience-Landmark","volume":"43 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141805784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knockdown of TGF-β in Pancreatic Cancer Helps Ameliorate Gemcitabine Resistance 抑制胰腺癌中的 TGF-β 有助于改善吉西他滨耐药性
Frontiers in Bioscience-Landmark Pub Date : 2024-07-25 DOI: 10.31083/j.fbl2907269
Xinxing Wang, Wei Su, Chuan Qin, Ruxin Gao, Shuai Shao, Xianwen Xu, Zhenhai Zhang, Junlin Gao
{"title":"Knockdown of TGF-β in Pancreatic Cancer Helps Ameliorate Gemcitabine Resistance","authors":"Xinxing Wang, Wei Su, Chuan Qin, Ruxin Gao, Shuai Shao, Xianwen Xu, Zhenhai Zhang, Junlin Gao","doi":"10.31083/j.fbl2907269","DOIUrl":"https://doi.org/10.31083/j.fbl2907269","url":null,"abstract":"","PeriodicalId":503756,"journal":{"name":"Frontiers in Bioscience-Landmark","volume":"16 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141804359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DHODH Alleviates Heart Failure via the Modulation of CoQ-Related Ferroptotic Inhibition DHODH 通过调节 CoQ 相关的铁抑制作用缓解心衰
Frontiers in Bioscience-Landmark Pub Date : 2024-07-24 DOI: 10.31083/j.fbl2907267
Chen Wang, Chuchu Chen, Jiabin Zhou, Jiayu Shi, Hanrui Sun, Jingyu Li, Pengyang Gu, Xinglin Wang, Qi Lu, Shuai Wang
{"title":"DHODH Alleviates Heart Failure via the Modulation of CoQ-Related Ferroptotic Inhibition","authors":"Chen Wang, Chuchu Chen, Jiabin Zhou, Jiayu Shi, Hanrui Sun, Jingyu Li, Pengyang Gu, Xinglin Wang, Qi Lu, Shuai Wang","doi":"10.31083/j.fbl2907267","DOIUrl":"https://doi.org/10.31083/j.fbl2907267","url":null,"abstract":"","PeriodicalId":503756,"journal":{"name":"Frontiers in Bioscience-Landmark","volume":"23 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141806230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Based on NF-κB and Notch1/Hes1 Signaling Pathways, the Mechanism of Artesunate on Inflammation in Osteoporosis in Ovariectomized Rats was Investigated 基于 NF-κB 和 Notch1/Hes1 信号通路，研究青蒿琥酯对卵巢切除大鼠骨质疏松症中炎症的影响机制
Frontiers in Bioscience-Landmark Pub Date : 2024-07-24 DOI: 10.31083/j.fbl2907266
Guangwei Wang, Jun Tan, Chongbo Huang, Yidong Xu, Zhong Yang, L. Huo
{"title":"Based on NF-κB and Notch1/Hes1 Signaling Pathways, the Mechanism of Artesunate on Inflammation in Osteoporosis in Ovariectomized Rats was Investigated","authors":"Guangwei Wang, Jun Tan, Chongbo Huang, Yidong Xu, Zhong Yang, L. Huo","doi":"10.31083/j.fbl2907266","DOIUrl":"https://doi.org/10.31083/j.fbl2907266","url":null,"abstract":"","PeriodicalId":503756,"journal":{"name":"Frontiers in Bioscience-Landmark","volume":"60 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141809406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microglia Involvement into Acute and Chronic Brain Damage in Diabetic Rats: Impact of GLP-1RA and SGLT-2i 小胶质细胞对糖尿病大鼠急性和慢性脑损伤的参与：GLP-1RA 和 SGLT-2i 的影响
Frontiers in Bioscience-Landmark Pub Date : 2024-07-24 DOI: 10.31083/j.fbl2907265
A. Simanenkova, Oksana Fuks, Natalia Timkina, Alina Islamova, Dina Sufieva, О. Kirik, Dmitrii Korzhevskii, Timur Vlasov, Tatiana Karonova
{"title":"Microglia Involvement into Acute and Chronic Brain Damage in Diabetic Rats: Impact of GLP-1RA and SGLT-2i","authors":"A. Simanenkova, Oksana Fuks, Natalia Timkina, Alina Islamova, Dina Sufieva, О. Kirik, Dmitrii Korzhevskii, Timur Vlasov, Tatiana Karonova","doi":"10.31083/j.fbl2907265","DOIUrl":"https://doi.org/10.31083/j.fbl2907265","url":null,"abstract":"","PeriodicalId":503756,"journal":{"name":"Frontiers in Bioscience-Landmark","volume":"36 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141809440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring Glypican-3 as a Molecular Target in Hepatocellular Carcinoma: Perspectives on Diagnosis and Precision Immunotherapy Strategies 探索作为肝细胞癌分子靶点的 Glypican-3：诊断和精准免疫疗法策略的前景
Frontiers in Bioscience-Landmark Pub Date : 2024-07-24 DOI: 10.31083/j.fbl2907268
Alireza Tojjari, Abdelrahman H. Hafez, Ali Saeed, Meghana Singh, Anwaar Saeed
{"title":"Exploring Glypican-3 as a Molecular Target in Hepatocellular Carcinoma: Perspectives on Diagnosis and Precision Immunotherapy Strategies","authors":"Alireza Tojjari, Abdelrahman H. Hafez, Ali Saeed, Meghana Singh, Anwaar Saeed","doi":"10.31083/j.fbl2907268","DOIUrl":"https://doi.org/10.31083/j.fbl2907268","url":null,"abstract":"","PeriodicalId":503756,"journal":{"name":"Frontiers in Bioscience-Landmark","volume":"7 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141809267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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