{"title":"Virtue of methotrexate in ectopic pregnancy","authors":"Salma Shaik, Lakshmi Manasa Venkata Sai, Kavya Rachamsetty, Dhachinamoorthi Duraiswamy, Rama Chandra Reddy L","doi":"10.26452/fjphs.v4i1.563","DOIUrl":"https://doi.org/10.26452/fjphs.v4i1.563","url":null,"abstract":"In recent times there is a shortfall of care about ectopic pregnancy among everyone, inciting conceded finding and potentially non -violent results. Ectopic pregnancy is a very dangerous medical disorder. This occurs when a fertilised egg implants outside of the uterus, generally in the fallopian tube. Making up 5%–10% of all pregnancy-related deaths, ectopic pregnancies are the leading cause of maternal death in the first trimester. Methotrexate is a folic acid inhibitor. It interferes with DNA synthesis and cell multiplication by inhibiting the spontaneous synthesis of purines and pyrimidines. Methotrexate will be used in the middle of six and eight weeks of pregnancy. The likelihood of a future pregnancy succeeding after using methotrexate is generally positive, according to studies. However, a few things could have an impact on these odds. As per to research, ectopic pregnancies are more common among women of reproductive age, usually between the ages of 20 and 35. Given that they are more likely to be sexually active and trying to get pregnant, women in this age range are at their most fertile. Additionally, the prevalence of sexually transmitted diseases (STIs) is higher in this age group, which can mark up the chance of an ectopic pregnancy. Factors affecting ectopic pregnancy risk include previous pelvic surgeries, infections, in vitro fertilization [IVF], endometriosis, smoking, assisted reproductive technologies, and tubal sterilization or previous pregnancies. This review of the literature attempts to shed insight on how methotrexate is currently used to treat ectopic pregnancies","PeriodicalId":503124,"journal":{"name":"Future Journal of Pharmaceuticals and Health Sciences","volume":"402 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140490467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A review on osteoarthritis","authors":"Rabbani Shaik, Surya Sritaja Podila, Ijaz Sheik","doi":"10.26452/fjphs.v3i4.526","DOIUrl":"https://doi.org/10.26452/fjphs.v3i4.526","url":null,"abstract":"Degenerative joint disease, or osteoarthritis (OA), is a prevalent chronic synovial joint condition characterized by non-inflammatory degeneration, leading to pain and restricted joint movement. OA patients navigate a spectrum of therapeutic options, from social media advice to prescriptions from primary care physicians. This article critically assesses evidence-based treatments for generalized or monoarticular OA, advocating multidisciplinary and multimodal therapy. Evaluation covers patient education, pharmaceuticals, complementary and alternative medicine, surgery, manual techniques, acupuncture, bracing, assistive devices, physical therapy, modalities, and interventional procedures (corticosteroid injection, viscosupplementation, pulsed radiofrequency). Optimal benefits emerge from early diagnosis and prevention combined with multidisciplinary and multimodal treatments. The review highlights the synergy of complementary therapies. Healthcare professionals should be well-versed in diverse OA management resources, emphasizing tailored treatment plans aligned with individual needs and encouraging healthier lifestyle choices for optimal patient outcomes.Top of Form","PeriodicalId":503124,"journal":{"name":"Future Journal of Pharmaceuticals and Health Sciences","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139210872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gautham Chakra R, Chandana Sai Y, Jyoshna V, Likhitha K, Tejeswini N, Iswarya N, Naga Lakshmi N
{"title":"The prescription pattern for coronary artery disease in tertiary care hospitals","authors":"Gautham Chakra R, Chandana Sai Y, Jyoshna V, Likhitha K, Tejeswini N, Iswarya N, Naga Lakshmi N","doi":"10.26452/fjphs.v3i4.525","DOIUrl":"https://doi.org/10.26452/fjphs.v3i4.525","url":null,"abstract":"The study aims to assess the current prescribing patterns for drugs managing Coronary Heart Disease (CHD) at the designated site to promote rational drug use in a specialized population. Conducted in the Medicine ward over six months, this observational retrospective study focused on patients consulting cardiologists for cardiac issues. Among lipid-lowering agents, rosuvastatin was the most prescribed (52.84%), followed by atorvastatin (43.15%). Anti-hypertensive agents were widely used, with beta-blockers, ACE inhibitors, and diuretics being popular choices. Adrenergic receptor blockers were common for hypertension, with metoprolol (55.7%) and bisoprolol (10.8%) frequently prescribed. ACE inhibitors, particularly Enalapril (65.6%), dominated prescriptions. Diuretics, including eplerenone (37.2%) and furosemide (33.3%), ranked third. The majority of patients were male, potentially linked to smoking and alcohol habits. Analysis revealed the prevalence of statins and anti-atherogenic agents in cardiovascular prescriptions. Beta-blockers, ACE inhibitors, and diuretics were prominent in managing hypertension.Top of Form","PeriodicalId":503124,"journal":{"name":"Future Journal of Pharmaceuticals and Health Sciences","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139238635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Background, Trends, Applications and Therapeutic Approaches of Nanoparticles: A Review","authors":"Saravanakumar Kasimedu, Hemalatha Palavuri, Swathi Puchakayala, Dhanalakshmi Rayavarapu, Akash Govindan, Harshitha Debbati, Niranjan Babu Mudduluru","doi":"10.26452/fjphs.v3i4.523","DOIUrl":"https://doi.org/10.26452/fjphs.v3i4.523","url":null,"abstract":"The development of nanoscience and nanotechnology in practically every field of science has simplified modern life. Since the arrangement of atoms in structures, electronics and systems produce their distinctive properties and functionalities on the scale of 1-100 nm. Beginning in the early 2000s, there was a rise in public discussion and understanding of the field which prompted the first commercial applications of nanotechnology. Nanotechnologies have a positive impact on almost all fields of study including physics, materials science, chemistry, biology, computer science and engineering. Notably, nanotechnologies have recently been employed with hopeful results to enhance human health, particularly in the field of cancer therapy. Understanding the nature of nanotechnology requires an understanding of the history of scientific discoveries that led to our current understanding of the field.","PeriodicalId":503124,"journal":{"name":"Future Journal of Pharmaceuticals and Health Sciences","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139260014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Overview of Contemporary Phenotypes, Present Challenges, and Novel Implications for Medical Services in the Diagnosis of Spinal Muscular Atrophy","authors":"Sujana A, Durga Prasad K, Divya E, Kalyani G","doi":"10.26452/fjphs.v3i4.524","DOIUrl":"https://doi.org/10.26452/fjphs.v3i4.524","url":null,"abstract":"Spinal muscular atrophy (SMA) is a form of muscle disease induced by SMN1 gene mutations. It can cause motor neurons and muscle strength to weaken. The intensity of the disease’s progression varies depending on the stage of development. Over the past ten years, new ways to help people with SMA have been found. These include the use of gene therapy and the modification of the SMN2 and SMN1 genes. First drugs approved for this condition were able to significantly alter the course of the disease. However, the evidence that is now available for these novel therapies is frequently constrained to a small range of individuals in terms of age and illness stage. To better understand the impact of treatment on people with all SMA subtypes and to build a platform for clinical decision-making in SMA, it will be necessary to gather real-world data with standardized outcome markers.","PeriodicalId":503124,"journal":{"name":"Future Journal of Pharmaceuticals and Health Sciences","volume":"259 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139260729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}