International Journal of Veterinary Medicine最新文献

{"title":"Retention periods of diagnostic dyes on a cut corneal wound","authors":"A. O. Minina, A. Bokarev, E. Y. Pilipets, E. V. Prudnikova","doi":"10.52419/issn2072-2419.2023.4.473","DOIUrl":"https://doi.org/10.52419/issn2072-2419.2023.4.473","url":null,"abstract":"Comparative  studies  of  four  main  ophthalmic dyes were carried out on their ability,  after  a  single  short-term  exposure,  to stain a corneal incised wound.12  year–old  Wistar  rats  weighing  180-220  grams  were  selected  for  the  study.  4 experimental  groups  of  3  rats  each  were formed from them. Corneal incision wounds were inflicted on all animals. A 10.0% lidocaine  solution  was  used  to  anesthetize  the cornea. Before applying the cut wound, the animals  were  injected  into  anesthesia  with the  drug  \"Sevoflurane\".  The  depth  of  the wound was monitored visually using a microscope  at  a  magnification  of  4-6  times. Next,  the  corneal  cut  wound  was  stained with various dyes: animals of group 1 – fluorescein, group 2 – riboflavin, group 3 – bengal  pink,  group  4 –  lissamine  green.  The exposure of all dyes, before eliminating the excess, was 1 minute.The degree of corneal staining was evaluated and photodocumented immediately after the  elimination  of  excess  dyes  and  further after 10 min., 20 min., 30 min., 60 min., 90 min., and 120 min. The cornea was visualized  and  photodocumented  using  a  microscope \"jingleszcn 315W\" at magnification x 6.0.For long-term studies, it is advisable to use bengal pink, which visualizes a wound defect within 60 minutes after staining. Lissamine green should be used in cases where a contrast is needed between the dye and the cornea,  and/or  the  underlying  structures  of the  eye.  Fluorescein  and  riboflavin  diffuse rapidly enough into the surrounding tissues, and also stain the tear film, which can give a false  positive  result  when  diagnosing  a wound defect of the cornea.","PeriodicalId":503015,"journal":{"name":"International Journal of Veterinary Medicine","volume":"129 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139174665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction of some metabolic parameters in cows during the milking period with the help of a feed additive","authors":"A. V. Sitchikhina, E. O. Saythanov, K. A. Gertseva, L. V. Nikulova","doi":"10.52419/issn2072-2419.2023.4.498","DOIUrl":"https://doi.org/10.52419/issn2072-2419.2023.4.498","url":null,"abstract":"The article is devoted to the assessment of changes in the clinical condition, hematological parameters, some biochemical blood parameters  reflecting  the  state  of  protein-carbohydrate metabolism in cows during the milking period, as well as the results of correction of this condition with a feed additive based  on humic acids \"Fulvat\".  The  article examines the physiological processes occurring  in  the  metabolism  of  cows  during  the newbody period  and  the period  of  separation, reflects the results of the studies conducted in assessing the dynamics and correction of the main critical indicators in hematological, biochemical blood parameters, as well  as  in  vital  changes  in  cows.  The  research  was  carried  out  using  modern  techniques, instruments and equipment. The object of the study was cows, 2-3 lactation of a black-and-white breed. All the animals were on tethered maintenance and a balanced diet. 2 groups were formed for research: experimental and control. The animals of the experimental  group  received  the  main  ration (OR)  +  the  feed  additive  \"Fulvat\"  for  60 days from the moment of calving; the cows of the control group were kept only on the main ration, without the use of additives in feeding. The feed additive was administered orally with the main diet, mixed with concentrated feed. The total time of observation of the indicators of homeostasis in animals was  60  days.  Studies  have  shown  that  the feed additive has a beneficial effect on erythropoiesis due to the presence of iron, cobalt, copper and other micro- and macroelements in the chemical composition, increasing the level  of  hemoglobin  in  the  experimental group on the 60th day of lactation by 19,7 %, reducing the  risk of developing  a ketogenic situation, increases the level of ionized calcium in the blood of animals, which in 2 times higher, compared with animals in the control group; normalizes the acidity of the scar  content  in  cows  of  the  experimental group and the preservation of the number of infusoria at the physiological level.","PeriodicalId":503015,"journal":{"name":"International Journal of Veterinary Medicine","volume":"12 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139173480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effectiveness of feed additives in chronic kidney disease in cats","authors":"S. N. Fedotkina, A. N. Shinkarenko, O. Strusovskaya","doi":"10.52419/issn2072-2419.2023.4.507","DOIUrl":"https://doi.org/10.52419/issn2072-2419.2023.4.507","url":null,"abstract":"Chronic kidney disease in cats is one of the most common diseases. The main direction of palliative therapy for chronic kidney disease  and  extending  the  survival  time  of cats  is  to  limit  phosphates  in  the  diet  and normalize the phosphorus content in the animal’s body. In order to reduce phosphates, phosphate  binders  are  used  -  substances whose mechanism of action is to bind excess phosphate  ions  in  the  gastrointestinal  tract, which  prevents  their  entry  into  the  blood-stream. The purpose of the study is to analyze  the  effectiveness  of  feed  additives “Urdetox” and “Ipakitine” in a comparative aspect in the palliative treatment of chronic kidney disease in cats. Determination of the biological activity of the proposed feed additive for cats with CKD in the form of tablets was  carried  out  on  the  basis  of  veterinary clinics in the city. Volgograd, St. Petersburg, Moscow, in the period 2021-2022. The objects  of  the  study  were  cats  whose  owners complained of loss of animal body weight, often  a  general  depressed  state,  decreased appetite,  periodic  vomiting,  frequent  urination, dull hair. The diagnosis and experiment were  carried  out  by  collecting  anamnestic data, determining clinical signs and laboratory data - a general urine test and a biochemical  analysis  of  blood  serum.  Studies  have shown that feed additives containing a phosphate binder and a detoxicant help eliminate the  main  clinical  manifestations  of  chronic renal failure. The introduction of the essential amino acid -taurine into the feed additive in the form of Urdetox tablets, as well as the accuracy of dosing and ease of use increase the effectiveness of its biological action.","PeriodicalId":503015,"journal":{"name":"International Journal of Veterinary Medicine","volume":"93 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139173052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combinations of pulmonary artery valve stenosis with other congenital heart defects in dogs","authors":"А. А. Trunov","doi":"10.52419/issn2072-2419.2023.4.457","DOIUrl":"https://doi.org/10.52419/issn2072-2419.2023.4.457","url":null,"abstract":"The  paper  presents  statistical  results  of identifying combinations of various congenital heart defects in dogs of different breeds diagnosed with pulmonary artery valve stenosis. The study was retrospective, conducted on the basis of the Department of General, Private and Operative Surgery, as well as in the veterinary clinic of neurology, traumatology and intensive care. The total sample  amounted  to  100  animals.  All  animals underwent a complete physical examination. The morphofunctional state of the heart was evaluated. Diagnosis was made by echocardiography  using  Doppler.  Each  congenital heart defect was evaluated and studied separately, noting its individual features and hemodynamic  changes  in  the  combination  of several congenital anomalies of heart development.  The  study  was  conducted  before performing surgical treatment of pulmonary artery valve stenosis by balloon plasty of the pulmonary artery valve. This study included animals with other cardiac anomalies in addition  to  obstructive  right  ventricular  outflow tract disease. Among 100 dogs examined, the most frequent combined heart defect was Fallot's tetrad. This pathology was singled out separately, as its mechanism of development  differs  significantly  from  a simple combination of several anomalies of heart development. It is believed that this is one heart defect consisting of several components. In addition, atrial septal defect, mitral or tricuspid valve dysplasia, open ductus arteriosus,  and  aortic  valve  stenosis  were found in combination with pulmonary valve stenosis. Combined heart defects were most common  in  French  Bulldog  dogs  in  this study, as this is the most common breed of dog diagnosed with pulmonary valve stenosis.","PeriodicalId":503015,"journal":{"name":"International Journal of Veterinary Medicine","volume":"20 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139173313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subconjunctival administration of \"Actilize\" for the treatment of small hemorrhages in the anterior chamber of the eye in cats with arterial hypertension","authors":"M. N. Argunov","doi":"10.52419/issn2072-2419.2023.4.486","DOIUrl":"https://doi.org/10.52419/issn2072-2419.2023.4.486","url":null,"abstract":"Systemic arterial hypertension can occur in  cats  for  a number of  reasons.  The  most common causes of hypertension in cats include  kidney  disease  (chronic  kidney  disease, chronic interstitial nephritis, amyloidosis, glomerulonephritis, pyelonephritis, polycystic  kidney  disease,  renal  dysplasia,  as well  as  acute  renal  failure),  chronic  heart failure,  endocrinopathy  (diabetes  mellitus, hyperthyroidism,  etc.),  obesity (hyperlipidemia), chronic anemia, polycythemia, fever, arteriovenous fistula, the use of food with a high salt content, idiopathic factors. Taking into account the above, we set a goal –  to  introduce  into  veterinary  clinical practice  an  effective  fibrinolytic  \"Actilize\"; to establish its effectiveness in lysis of small hemorrhages in the anterior chamber of the eye with arterial hypertension of cats, as well as prevention and treatment of synechiae; to work  out  a  subconjunctival  method  of  administration of \"Actilize\" at the entrance of long  ciliary  arteries.  The  basis  of  the  research  methodology  was  a  scientifically based formulation of the problem, methods and means of lysis of small blood clots in the anterior chamber of the eye, prevention and treatment  of  synechiae  in  cats  with  arterial hypertension,  ensuring  maximum  effectiveness by improving existing treatment protocols,  as  well  as  testing  \"Actilize\"  and  the subconjunctival method of its introduction in the area of the entrance of long ciliary arteries  for  treatment  small  hemorrhages  in  the anterior  chamber  of  the  eye  with  arterial hypertension  of  cats  in  veterinary  ophthalmology. Thanks to the experiments, we were able  to  introduce  into  veterinary  clinical practice an  effective fibrinolytic \"Actilize\"; to establish its effectiveness in lysis of small blood  clots  in  the  anterior  chamber  of  the eye  with  arterial  hypertension  of  cats,  prevention and treatment of synechiae; to work out  a  minimally  invasive  subconjunctival method of administration of \"Actilize\" at the entrance of long ciliary arteries. In the case of extensive hyphema with arterial hypertension  of  cats,  followed  by  the  formation  of large blood clots, we recommended an intracameral  method  of  introducing  \"Actilize\" into the anterior chamber of the eye.","PeriodicalId":503015,"journal":{"name":"International Journal of Veterinary Medicine","volume":"285 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139174859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphological and biochemical blood profile of dairy cows affected by traumatic reticulitis","authors":"E. L. Popova, A. V. Ryzhakov, Y. Oshurkova, L. L. Fomina","doi":"10.52419/issn2072-2419.2023.4.492","DOIUrl":"https://doi.org/10.52419/issn2072-2419.2023.4.492","url":null,"abstract":"Feed injuries and the presence of foreign bodies in the digestive system of cows can be one of the reasons for a decrease in milk yields  and  premature  culling  of  animals. Blood tests in most cases can help determine the degree of exposure of foreign bodies to the  animal's  body.  Morphological  and  biochemical blood analysis can show the presence of inflammation, infection or other diseases associated with the persistence of foreign bodies in the digestive system of cows. Also,  a  blood  test  can  help  determine  the effectiveness of various methods of treating feed  injuries  in  animals.  The  present  study was conducted to study the effect of foreign bodies in the mesh on the morphological and biochemical  profile  of  blood  and  serum  of cattle. The object of the study were Ayrshire cows with a diagnosis of traumatic reticulitis and healthy animals. As a result of the study, we obtained reliable values of deviations in the  morphological  and  biochemical  profile for such indicators as hemoglobin and alkaline  phosphatase.  Taking  into  account  the analysis of the literature and the results obtained  by  us,  traumatic  reticulitis  in  cattle cannot be diagnosed on the basis of individual  laboratory  blood  tests,  since  even  the most  common  deviations  can  not  be  observed in all diseased cows. Many of these indicators are not specific to traumatic reticulitis and may occur in other diseases of the abdominal  cavity  and  chest.  A  preliminary diagnosis can be made only on the basis of all clinical and laboratory data.","PeriodicalId":503015,"journal":{"name":"International Journal of Veterinary Medicine","volume":"16 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139175269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}