Journal of oncology: diagnostic radiology and radiotherapy最新文献

筛选
英文 中文
8th Edition AJCC/UICC Staging of Cancers of the Esophagus and Esophagogastric Junction 第 8 版 AJCC/UICC 食管和食管胃交界处癌症分期
Journal of oncology: diagnostic radiology and radiotherapy Pub Date : 2024-07-04 DOI: 10.37174/2587-7593-2024-7-2-76-85
O. B. Abu-Haidar, I. Gladilina, P. V. Kononets, A. A. Tryakin
{"title":"8th Edition AJCC/UICC Staging of Cancers of the Esophagus and Esophagogastric Junction","authors":"O. B. Abu-Haidar, I. Gladilina, P. V. Kononets, A. A. Tryakin","doi":"10.37174/2587-7593-2024-7-2-76-85","DOIUrl":"https://doi.org/10.37174/2587-7593-2024-7-2-76-85","url":null,"abstract":"Staging of cancer of the esophagus and esophagogastric junction (EGJ), presented in the 8th edition American Joint Committee on Cancer (AJCC). Cancer Staging was derived from the Worldwide Esophageal Cancer Collaboration (WECC). The 8th edition of the American Joint Committee on Cancer (AJCC) staging of the esophagus cancers and esophagogastric junction presents separate classifications for clinical (cTNM), pathologic (pTNM), and pathologic after neoadjuvant treatment (ypTNM). In this article changes presented between the 7th and 8th editions of this TNM classification. These changes included separate clinical, pathological and pathological prognostic staging for adenocarcinomas and squamous cell cancer.","PeriodicalId":502542,"journal":{"name":"Journal of oncology: diagnostic radiology and radiotherapy","volume":" 64","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141680112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumor of the Renal Pelvis Accompanying Coral Nephrolithiasis 伴有珊瑚虫性肾炎的肾盂肿瘤
Journal of oncology: diagnostic radiology and radiotherapy Pub Date : 2024-07-04 DOI: 10.37174/2587-7593-2024-7-2-98-104
I. S. Grashchenko, N. T. Drobot, A. V. Klimov, O. A. Halmurzaev, S. D. Bejanova, B. Medvedeva, K. A. Romanova, E. Kolobanova, M. G. Lapteva, A. B. Lukianchenko
{"title":"Tumor of the Renal Pelvis Accompanying Coral Nephrolithiasis","authors":"I. S. Grashchenko, N. T. Drobot, A. V. Klimov, O. A. Halmurzaev, S. D. Bejanova, B. Medvedeva, K. A. Romanova, E. Kolobanova, M. G. Lapteva, A. B. Lukianchenko","doi":"10.37174/2587-7593-2024-7-2-98-104","DOIUrl":"https://doi.org/10.37174/2587-7593-2024-7-2-98-104","url":null,"abstract":"Cancer of the renal pelvis, in particular the squamous cell form, is an extremely rare neoplasm of this localization. Chronic inflammation is thought to be a risk factor for this disease due to the presence of stones in the collecting system. Having no specific clinical manifestations, this tumor is often an incidental finding identified during examination of patients for other reasons.This article presents a clinical case of squamous cell carcinoma of the renal pelvis in a patient with a long course of urolithiasis and the presence of staghorn stones, complicated by a kidney abscess diagnosed by CT and MRI.","PeriodicalId":502542,"journal":{"name":"Journal of oncology: diagnostic radiology and radiotherapy","volume":" 59","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141680035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary Radiodiagnosis of Skeletal Changes in the Onset of Multiple Myeloma, Approaches to Differential Radiodiagnosis (Observations from Practice) 多发性骨髓瘤发病时骨骼变化的初级放射诊断,鉴别放射诊断的方法(实践观察)
Journal of oncology: diagnostic radiology and radiotherapy Pub Date : 2024-07-04 DOI: 10.37174/2587-7593-2024-7-2-55-62
A. V. Laryukov, E. K. Laryukova, F. F. Gubaidullina, Z. F. Mazitova
{"title":"Primary Radiodiagnosis of Skeletal Changes in the Onset of Multiple Myeloma, Approaches to Differential Radiodiagnosis (Observations from Practice)","authors":"A. V. Laryukov, E. K. Laryukova, F. F. Gubaidullina, Z. F. Mazitova","doi":"10.37174/2587-7593-2024-7-2-55-62","DOIUrl":"https://doi.org/10.37174/2587-7593-2024-7-2-55-62","url":null,"abstract":"Multiple myeloma — Rustitzky-Kahler disease is the most common tumor of the group of Ig-secreting lymphomas. The article presents the difficulties of radiodiagnosis assessment of skeletal changes in the initial stages of multiple myeloma, when bone pain is the only clinical manifestation, and X-ray examination reveals single large foci of destruction. These observations emphasize the important role of assessment and interpretation of bone changes in such situations, which can be the main guiding factor in choosing an examination algorithm for making a correct diagnosis. The article is of interest to radiation diagnosticians, it presents literature data and issues of differential radiodiagnosis of skeletal changes in multiple myeloma.","PeriodicalId":502542,"journal":{"name":"Journal of oncology: diagnostic radiology and radiotherapy","volume":" 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141677949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Standards for the Transarterial Chemoembolization Procedure as the Hepatocellular Carcinoma Treatment: Literature Review. Part 1 经动脉化疗栓塞术治疗肝细胞癌的标准:文献综述。第一部分
Journal of oncology: diagnostic radiology and radiotherapy Pub Date : 2024-07-04 DOI: 10.37174/2587-7593-2024-7-2-63-75
I.  . Pogrebnyakov
{"title":"Standards for the Transarterial Chemoembolization Procedure as the Hepatocellular Carcinoma Treatment: Literature Review. Part 1","authors":"I.  . Pogrebnyakov","doi":"10.37174/2587-7593-2024-7-2-63-75","DOIUrl":"https://doi.org/10.37174/2587-7593-2024-7-2-63-75","url":null,"abstract":"The review describes the modern classification of stages of HCC, features of radiological diagnostics, the indications for morphological verification, shows the criteria for selecting patients for endovascular treatment, and outlines all the indications and contraindications for the TACE procedure. The review shows the features of preoperative preparation, describes TACE techniques for HCC, and algorithms for their implementation.","PeriodicalId":502542,"journal":{"name":"Journal of oncology: diagnostic radiology and radiotherapy","volume":" 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141678325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PET/CT with 18F-PSMA-1007 in Diagnostics of Primary and Recurrent Lesions of Clear-cell Renal Cell Carcinoma in Comparison with 18F-FDG: Prospective Study 使用 18F-PSMA-1007 的 PET/CT 诊断透明细胞肾细胞癌的原发和复发病灶与 18F-FDG 的比较:前瞻性研究
Journal of oncology: diagnostic radiology and radiotherapy Pub Date : 2024-07-04 DOI: 10.37174/2587-7593-2024-7-2-15-26
V. S. Ilyakov, A. Pronin, A. V. Parnas, A. Subbotin, A. Krylov, T. Geliashvili, E. V. Bezumova, O. V. Mehedova, N. I. Nesterova, V. Matveev
{"title":"PET/CT with 18F-PSMA-1007 in Diagnostics of Primary and Recurrent Lesions of Clear-cell Renal Cell Carcinoma in Comparison with 18F-FDG: Prospective Study","authors":"V. S. Ilyakov, A. Pronin, A. V. Parnas, A. Subbotin, A. Krylov, T. Geliashvili, E. V. Bezumova, O. V. Mehedova, N. I. Nesterova, V. Matveev","doi":"10.37174/2587-7593-2024-7-2-15-26","DOIUrl":"https://doi.org/10.37174/2587-7593-2024-7-2-15-26","url":null,"abstract":"Introduction: Attempts have been made to use various RPs, other than 18F-FDG in the diagnostics of renal cell carcinoma (RCC), with promising results demonstrated by PSMA-specific RPs, in particular 18F-PSMA-1007.A prospective study was conducted at N.N. Blokhin NMRCO to establish capabilities of PET/CT with 18F-FDG and 18F-PSMA-1007 in primary and recurrent ccRCC diagnostics.Material and methods: Forty-eight patients were included in the study, 28 with renal masses and 20 with suspected local recurrence of ccRCC. Biopsy results were available in all patients. All patients underwent PET/CT with 18F-PSMA-1007 and 18F-FDG.Results: Thirty-nine renal neoplasms were identified in 28 patients. 24 of 39 foci (21 patients) were PSMA-positive and 18 of 39 foci (16 patients) were FDG-positive. No false-positive foci were identified. The sensitivity, specificity, positive and negative predictive value in primary RCC were: for 18F-PSMA-1007 — 75, 100, 100 and 85 %, respectively; for 18FDG — 57, 100, 100 and 76 %, respectively. The SUVmax level of 18F-PSMA-1007 exceeded 18FDG in 27 of 28 patients (38 foci); the tumor/background ratio was higher in 16 of 28 patients (24 foci). Tumor thrombosis was detected in 6 patients (PSMA-positive 6 of 6, FDG-positive 5 of 6). PSMA-SUVmax levels in thrombi exceeded 18FDG in all patients, tumor/background ratio in 5 out of 6 patients. Local recurrence was detected in 13 of 20 patients (27 foci). 10 foci in the remaining 7 patients were considered as false positives. No false-negative results were obtained. Sensitivity, specificity, positive and negative predictive value in the diagnosis of local recurrence of ccPCC: 18F-PSMA-1007 — 100, 94, 81 and 100 %, respectively; 18FDG -100, 89, 68 and 100 %, respectively.SUVmax and tumor/background ratio were found to correlate with primary tumor and recurrent node sizes for both RPs.Discussion and conclusions: At the moment, the role of 18F-PSMA-1007 in RCC diagnostics has not been defined. We can note the high efficiency of this RP in the assessment of the primary focus and recurrence of ccRCC, its usage is justified in cases, when routine diagnostic methods do not give an unambiguous answer.The possibilities of 18F-PSMA-1007 in metastatic ccRCC diagnostics are of the greatest interest. A significant prospective material has been collected in our department, which will be the basis for further study of this RP in the diagnostics of metastatic ccRCC.","PeriodicalId":502542,"journal":{"name":"Journal of oncology: diagnostic radiology and radiotherapy","volume":" 33","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141679791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intrapulmonary Lymph Nodes in Patients with Extrapulmonary Solid Tumors 肺外实体瘤患者的肺内淋巴结
Journal of oncology: diagnostic radiology and radiotherapy Pub Date : 2024-07-04 DOI: 10.37174/2587-7593-2024-7-2-46-54
V. A. Biakhova, I. E. Turin
{"title":"Intrapulmonary Lymph Nodes in Patients with Extrapulmonary Solid Tumors","authors":"V. A. Biakhova, I. E. Turin","doi":"10.37174/2587-7593-2024-7-2-46-54","DOIUrl":"https://doi.org/10.37174/2587-7593-2024-7-2-46-54","url":null,"abstract":"Purpose: To clarify the possibility of metastatic lesions of intrapulmonary lymph nodes in patients with malignant neoplasms of extrapulmonary localization by analyzing retrospective and prospective material.Material and methods: Our study included 139 patients. The criterion for selecting patients was a morphologically confirmed on­cological diagnosis and the presence of lesions in the lungs. Patients were recruited from two large groups of leading localizations in the general structure of cancer incidence: a group of patients with colorectal cancer — 76 (54.7 %) and a group of patients with malignant breast tumors — 63 (45.3 %). A total of 312 lung lesions were identified and analyzed in 139 patients. High-resolution computed tomography with a slice thickness of up to 1-1.5 mm of the chest was performed in all patients. Assessment of dynamics in all patients was carried out for at least 3 years.Results: As a result, out of 139 patients with newly detected lesions in the lungs, 43 (30.9 %) patients had lesions identified, which we classified as intrapulmonary regional lymph nodes (RLNs). A total of 75 (24.0 %) lesions classified as typical or atypical RLNs were identified. We obtained the following data: RLNs were located predominantly in the lower lobes — 46.7 %, 84 % of RLNs were localized below the carina. A total of 37.3 % of lesions were classified as perifissural lesions, 62.7 % of identified lesions were classified as subpleural (peripleural) lesions. It was found that the RLNs were localized on the pleura or had a connection with it through a thin septum — 49.3 % and 38.7 %, respectively. The average diameter of the RLN in the lung was 4.0 mm. RLNs were triangular in shape in 64 %, round (lenticular) in 21.3 %, and oval in 14.7 % of cases. 96 % of the lesions we classified as RLN were monitored over time using HRCT for 3 years or more, 4 % of the lesions underwent surgical treatment. All the lesions that we observed over the course of 3 years remained without dynamics. Based on the data obtained, we concluded that RLNs in patients with solid tumors of extrapulmonary locations and lesions in the lungs are benign changes and do not require dynamic monitoring.Conclusions: Lesions in patients with solid tumors of extrapulmonary localization classified as RLN are benign changes and do not affect the stage and nature of the treatment, and also do not require dynamic monitoring.","PeriodicalId":502542,"journal":{"name":"Journal of oncology: diagnostic radiology and radiotherapy","volume":" 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141678586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiosurgical Maintenance of Indeterminate Proximal Biliary Stricture. Clinical Observation 放射外科手术维持不确定的近端胆道狭窄。临床观察
Journal of oncology: diagnostic radiology and radiotherapy Pub Date : 2024-07-04 DOI: 10.37174/2587-7593-2024-7-2-86-97
S. M. Abdulkarimova, O. N. Sergeeva, I.  . Pogrebnyakov, E. R. Virschke, E. A. Nasonova, D. Frantsev, E. V. Uryumova, M. G. Lapteva, E. Moroz, O. V. Chistyakova, B. Dolgushin
{"title":"Radiosurgical Maintenance of Indeterminate Proximal Biliary Stricture. Clinical Observation","authors":"S. M. Abdulkarimova, O. N. Sergeeva, I.  . Pogrebnyakov, E. R. Virschke, E. A. Nasonova, D. Frantsev, E. V. Uryumova, M. G. Lapteva, E. Moroz, O. V. Chistyakova, B. Dolgushin","doi":"10.37174/2587-7593-2024-7-2-86-97","DOIUrl":"https://doi.org/10.37174/2587-7593-2024-7-2-86-97","url":null,"abstract":"The paper presents a case of an indeterminate proximal biliary stricture in a patient who admitted to the N.N. Blokhin National Medical Research Center of Oncology with a referral diagnosis of Klatskin tumor and 6 years earlier had undergone cholecystectomy for calculous cholecystitis complicated by Mirizzi syndrome. The authors highlight the difficulties of biliary lesion differentiation as well as the importance of anamnestic, clinical, imaging, laboratory and morphological data synthesis with the emphasis on percucationous endobiliary interventions to establish the etiology of the disease.","PeriodicalId":502542,"journal":{"name":"Journal of oncology: diagnostic radiology and radiotherapy","volume":" 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141679996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PET/CT with 68Ga-DOTA-TATE and 68Ga-FAPI in the Diagnosis of Neuroendocrine Tumors. Clinical Cases 使用 68Ga-DOTA-TATE 和 68Ga-FAPI 的 PET/CT 诊断神经内分泌肿瘤。临床病例
Journal of oncology: diagnostic radiology and radiotherapy Pub Date : 2024-07-04 DOI: 10.37174/2587-7593-2024-7-2-9-14
E. V. Belkin, P. E. Tulin, A. Odzharova
{"title":"PET/CT with 68Ga-DOTA-TATE and 68Ga-FAPI in the Diagnosis of Neuroendocrine Tumors. Clinical Cases","authors":"E. V. Belkin, P. E. Tulin, A. Odzharova","doi":"10.37174/2587-7593-2024-7-2-9-14","DOIUrl":"https://doi.org/10.37174/2587-7593-2024-7-2-9-14","url":null,"abstract":"Purpose: To perform a comparative analysis of diagnostic efficiency of PET/CT with 68Ga-DOTA-TATE and 68Ga-FAPI on the example of clinical cases of NEO (detection of primary tumor and extra-organ metastases).Material and methods: Two patients with pancreatic NEO underwent PET/CT studies with 68Ga-DOTA-TATE and 68Ga-FAPI before treatment. PET/CT with 68Ga-DOTA-TATE successfully visualized primary tumors in both patients; evidence of a metastatic process in the liver was obtained in one patient. PET/CT with 68Ga-FAPI showed non-optimal visualization of primary tumors, no liver metastases were detected.Conclusion: PET/CT with 68Ga-DOTA-TATE is a more effective method of radionuclide diagnostics of NEO than PET/CT with 68Ga-FAPI.","PeriodicalId":502542,"journal":{"name":"Journal of oncology: diagnostic radiology and radiotherapy","volume":" 88","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141680063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Features of PET/CT Description with 18F-Fluoroestradiol in Patients with Estrogen-Positive Breast Cancer 使用 18F- 氟雌二醇对雌激素阳性乳腺癌患者进行 PET/CT 分析的特点
Journal of oncology: diagnostic radiology and radiotherapy Pub Date : 2024-07-04 DOI: 10.37174/2587-7593-2024-7-2-27-36
A. V. Parnas, A. Pronin, D. Ryabchikov, P. E. Tulin, A. Subbotin, V. S. Ilyakov, N. V. Cherepanova, Yu. I. Prokofiev
{"title":"Features of PET/CT Description with 18F-Fluoroestradiol in Patients with Estrogen-Positive Breast Cancer","authors":"A. V. Parnas, A. Pronin, D. Ryabchikov, P. E. Tulin, A. Subbotin, V. S. Ilyakov, N. V. Cherepanova, Yu. I. Prokofiev","doi":"10.37174/2587-7593-2024-7-2-27-36","DOIUrl":"https://doi.org/10.37174/2587-7593-2024-7-2-27-36","url":null,"abstract":"Purpose: To study possible errors in the interpretation and analysis of PET/CT studies with 18F-FES performed in patients with estrogen receptor-positive breast tumors.Material and methods: Data PET/CT with 18F-FES from 140 PET patients were retrospectively analyzed from 2017 to 2023. The study included patients with histologically confirmed estrogen receptor-positive breast cancer, before the start of specific treat­ment, as well as when progression is detected or if a metastatic process is suspected at the initial examination stage.Results: Recommendations are given for the assessment and interpretation of various changes detected during PET/CT with 18F-FES in patients with estrogen receptor-positive breast cancer, which may cause difficulties in analyzing the results of the study.Conclusion: Although the PET/CT with 18F-FES in our country has not yet been widely introduced into clinical practice, in some institutions the study is carried out within the framework of scientific protocols and in complex cases of differential diagnosis. For a more correct interpretation of PET/CT with 18F-FES should take into account the clinical and morphological features in each clinical case.","PeriodicalId":502542,"journal":{"name":"Journal of oncology: diagnostic radiology and radiotherapy","volume":" 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141677962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Method for Assessing Local Metabolism of Mammary Tumors Based on Multimodal Optical Technology 基于多模态光学技术的乳腺肿瘤局部代谢评估方法
Journal of oncology: diagnostic radiology and radiotherapy Pub Date : 2024-07-04 DOI: 10.37174/2587-7593-2024-7-2-37-45
M. Arabachyan, V. Shupletsov, M. Kirillin, A. Dunaev, E. V. Potapova
{"title":"Method for Assessing Local Metabolism of Mammary Tumors Based on Multimodal Optical Technology","authors":"M. Arabachyan, V. Shupletsov, M. Kirillin, A. Dunaev, E. V. Potapova","doi":"10.37174/2587-7593-2024-7-2-37-45","DOIUrl":"https://doi.org/10.37174/2587-7593-2024-7-2-37-45","url":null,"abstract":"Introduction. Breast cancer (BC) is the most common malignant tumor in women worldwide. It amounts more than 16 % of all cases of malignant neoplasms in women. Modern advances in radiological methods of breast tumors detection significantly increased the number of non-palpable neoplasms revealed during examinations, while further progress requires the development of improved minimally invasive techniques for obtaining biopsy material from breast tumors using tools of navigational controls. An approach with high potential for direct evaluation of local tumor metabolism consists in complementary use of fluorescence spectroscopy and diffuse reflectance spectroscopy.Purpose: Evaluation of the effectiveness of a new complementary approach for the diagnosis of the metabolic status of breast tumors in patients suspicious for breast cancer.Material and methods. This article presents the results of the examination of 21 patients with breast neoplasms who, in addition to standard examination methods, including ultrasound, X-ray mammography, puncture biopsy and trepanobiopsy, were subject to evaluation of local tumor metabolism with complementary employment of fluorescence spectroscopy and diffuse reflectance spectroscopy .Results. It has been established that the malignant breast tumors have lower saturation values compared with both benign tumors and the surrounding healthy tissue: StO2(BC) = 6,6 % [5,7-24,8 %]; 79,0 % [77,6-84,4 %], StO2(fibroadenoma) = 66,3 %[43,7-74,8 %]. It is also found that the malignant tumors have higher values of NADPH compared with the benign tumors (INAD(P) H(BC) = 6157 a.u. [2188-8814 a.u.]; INADH (fibroadenoma) = 2962 a.u. [1924-4301 a.u. ]).Conclusion. The new method of the diagnosis of the local breast tumor metabolism can be further used to improve the results of targeted biopsies under ultrasound control and to assess the therapeutic pathomorphosis of BC. To evaluate the effectiveness of this diagnostic method, it is necessary to continue the study with a larger number of patients in order to obtain statistically reliable data.","PeriodicalId":502542,"journal":{"name":"Journal of oncology: diagnostic radiology and radiotherapy","volume":" 42","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141679384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信