Annals of the Academy of Medicine, Singapore最新文献_第8页

The efficacy and safety of radiofrequency ablation in papillary thyroid carcinoma: A systematic review and meta-analysis. 射频消融治疗甲状腺乳头状癌的疗效和安全性：一项系统综述和荟萃分析。

IF 2

Annals of the Academy of Medicine, Singapore Pub Date : 2025-03-14 DOI: 10.47102/annals-acadmedsg.2024241

Wei Shuen Clarissa Cheong, Xin Yi Joy Au, Ming Yann Lim, Ernest Weizhong Fu, Hao Li, Uei Pua, Yong Quan Alvin Soon, Yijin Jereme Gan

{"title":"The efficacy and safety of radiofrequency ablation in papillary thyroid carcinoma: A systematic review and meta-analysis.","authors":"Wei Shuen Clarissa Cheong, Xin Yi Joy Au, Ming Yann Lim, Ernest Weizhong Fu, Hao Li, Uei Pua, Yong Quan Alvin Soon, Yijin Jereme Gan","doi":"10.47102/annals-acadmedsg.2024241","DOIUrl":"10.47102/annals-acadmedsg.2024241","url":null,"abstract":"Introduction: Radiofrequency ablation (RFA) avoids the complications of general anaesthesia, reduces length of hospitalisation and reduces morbidity from surgery. As such, it is a strong alternative treatment for patients with comorbidities who are not surgical candidates. However, to our knowledge, there have only been 1 systematic review and 3 combined systematic review and meta-analyses on this topic to date. This systematic review and meta-analysis seeks to evaluate the efficacy and safety of RFA in the treatment of papillary thyroid carcinoma (PTC) with longer follow-up durations.Method: PubMed, Embase and Cochrane databases were searched for relevant studies published from 1990 to 2021; 13 studies with a total of 1366 patients were included. The Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines and Sandelowski et al.'s approach1 to \"negotiated consensual validation\" were used to achieve consensus on the final list of articles to be included. All authors then assessed each study using a rating scheme modified from the Oxford Centre for Evidence-Based Medicine.Results: Pooled volume reduction rates (VRRs) from 1 to 48 months after RFA, complete disappearance rates (CDR) and complications were assessed. Pooled mean VRRs were 96.59 (95% confidence interval [CI] 91.05-102.13, I2=0%) at 12 months2-6 and 99.31 (95% CI 93.74-104.88, I2=not applicable) at 48 months.2,5 Five studies showed an eventual CDR of 100%.2,4,7-9 No life-threatening complications were recorded. The most common complications included pain, transient voice hoarseness, fever and less commonly, first-degree burn.Conclusion: RFA may be an effective and safe alternative to treating PTC. Larger clinical trials with longer follow-up are needed to further evaluate the effectiveness of RFA in treating PTC.","PeriodicalId":502093,"journal":{"name":"Annals of the Academy of Medicine, Singapore","volume":"54 3","pages":"170-177"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143775178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Complexity in primary care: Beyond multimorbidity in Healthier SG. 初级保健的复杂性：在更健康的SG中超越多病。

IF 2.5

Annals of the Academy of Medicine, Singapore Pub Date : 2025-02-27 DOI: 10.47102/annals-acadmedsg.202522

Sky Wei Chee Koh, Howard Bauchner

引用次数: 0

Beyond BMI: The Janus-like effect of muscle versus fat on midlife women's health. 超越BMI：肌肉和脂肪对中年女性健康的双重影响。

IF 2.5

Annals of the Academy of Medicine, Singapore Pub Date : 2025-02-27 DOI: 10.47102/annals-acadmedsg.2024278

Eu-Leong Yong, Beverly Wen Xin Wong, Darren Yuen Zhang Tan

引用次数: 0

Adolescent self-harm and suicide attempts in the emergency department in Singapore. 新加坡急诊科的青少年自残和自杀企图。

IF 2.5

Annals of the Academy of Medicine, Singapore Pub Date : 2025-02-27 DOI: 10.47102/annals-acadmedsg.202531

Say How Ong

引用次数: 0

Development and validation of the sarcopenia composite index: A comprehensive approach for assessing sarcopenia in the ageing population. 肌少症综合指数的发展和验证：一种评估老年人群肌少症的综合方法。

IF 2.5

Annals of the Academy of Medicine, Singapore Pub Date : 2025-02-27 DOI: 10.47102/annals-acadmedsg.2024272

Hsiu-Wen Kuo, Chih-Dao Chen, Amy Ming-Fang Yen, Chenyi Chen, Yang-Teng Fan

{"title":"Development and validation of the sarcopenia composite index: A comprehensive approach for assessing sarcopenia in the ageing population.","authors":"Hsiu-Wen Kuo, Chih-Dao Chen, Amy Ming-Fang Yen, Chenyi Chen, Yang-Teng Fan","doi":"10.47102/annals-acadmedsg.2024272","DOIUrl":"10.47102/annals-acadmedsg.2024272","url":null,"abstract":"Introduction: The diagnosis of sarcopenia relies on key indicators such as handgrip strength, walking speed and muscle mass. Developing a composite index that integrates these measures could enhance clinical evaluation in older adults. This study aimed to standardise and combine these metrics to establish a z score for the sarcopenia composite index (ZoSCI) tailored for the ageing population. Additionally, we explore the risk factors associated with ZoSCI to provide insights into early prevention and intervention strategies.Method: This retrospective study analysed data between January 2017 and December 2021 from an elderly health programme in Taiwan, applying the Asian Working Group for Sarcopenia criteria to assess sarcopenia. ZoSCI was developed by standardising handgrip strength, walking speed and muscle mass into z scores and integrating them into a composite index. Receiver operating characteristic (ROC) curve analysis was used to determine optimal cut-off values, and multiple regression analysis identified factors influencing ZoSCI.Results: Among the 5047 participants, the prevalence of sarcopenia was 3.7%, lower than the reported global prevalence of 3.9-15.4%. ROC curve analysis established optimal cut-off points for distinguishing sarcopenia in ZoSCI: -1.85 (sensitivity 0.91, specificity 0.88) for males and -1.97 (sensitivity 0.93, specificity 0.88) for females. Factors associated with lower ZoSCI included advanced age, lower education levels, reduced exercise frequency, lower body mass index and creatinine levels.Conclusion: This study introduces ZoSCI, a new compo-site quantitative indicator for identifying sarcopenia in older adults. The findings highlight specific risk factors that can inform early intervention. Future studies should validate ZoSCI globally, with international collaborations to ensure broader applicability.","PeriodicalId":502093,"journal":{"name":"Annals of the Academy of Medicine, Singapore","volume":"54 2","pages":"101-112"},"PeriodicalIF":2.5,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Digital health's impact on the patient-doctor relationship in a primary healthcare setting: A qualitative study. 数字健康对初级卫生保健环境中医患关系的影响：一项定性研究。

IF 2.5

Annals of the Academy of Medicine, Singapore Pub Date : 2025-02-27 DOI: 10.47102/annals-acadmedsg.2024341

Kai Ping Sze, Yean Lyi Lim, Qi Wei Fong, Jacqueline Giovanna de Roza, Poay Sian Sabrina Lee, Eng Sing Lee, Shu Yun Tan

引用次数: 0

Adolescent self-harm and suicide attempts: An analysis of emergency department presentations in Singapore. 青少年自残和自杀企图：新加坡急诊科报告分析。

IF 2.5

Annals of the Academy of Medicine, Singapore Pub Date : 2025-02-27 DOI: 10.47102/annals-acadmedsg.2024334

Darren Kai Siang Chong, Vicknesan Jeyan Marimuttu, Pei Shan Hoe, Chu Shan Elaine Chew, Angelina Su Yin Ang

{"title":"Adolescent self-harm and suicide attempts: An analysis of emergency department presentations in Singapore.","authors":"Darren Kai Siang Chong, Vicknesan Jeyan Marimuttu, Pei Shan Hoe, Chu Shan Elaine Chew, Angelina Su Yin Ang","doi":"10.47102/annals-acadmedsg.2024334","DOIUrl":"10.47102/annals-acadmedsg.2024334","url":null,"abstract":"Introduction: The rising rate of adolescent suicide, and the burden of self-harm and mental health disorders, pose significant threats to Singapore's future health outcomes and human potential. This study sought to examine the risk profile and healthcare utilisation patterns of Singaporean adolescents who presented to the emergency department (ED) for suicidal or self-harm behaviour.Method: A retrospective review of medical records for patients aged 10 to 19 years who visited Singapore's KK Women's and Children's Hospital ED for suicidal or self-harm attempts from January to December 2021 was conducted.Results: A total of 221 patients were identified, with a predominance of female patients (85.5%) over males (14.5%). The mean age was 14.2 ± 1.4 years. Intentional drug overdose (52.0%) was the most commonly used method. Significantly more females presented for intentional paracetamol overdose (46.6% versus [vs] 28.1%, P=0.049), whereas jumping from a height was more common among males (18.8% vs 5.8%, P=0.022). The most frequently observed mental health challenges were stress-related and emotional coping difficulties (50.7%), followed by mood and anxiety symptoms (53.4%). A history of self-harm and suicidal behaviours were the most common psychosocial risk factors. Within the year prior to their ED presentation, 15.4% had accessed healthcare services for mild medical ailments, 19.5% for medically unexplained symptoms, and 17.2% for previous self-harm or suicide attempts.Conclusion: Most cases involved psychosocial and emotional regulation difficulties, some of which displayed sex-specific patterns, rather than complex psychiatric disorders. The identified predictive factors can help inform Singapore's National Mental Health and Well-being Strategy, to guide targeted and transdiagnostic interventions in schools and community settings.","PeriodicalId":502093,"journal":{"name":"Annals of the Academy of Medicine, Singapore","volume":"54 2","pages":"78-86"},"PeriodicalIF":2.5,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Infected ovarian endometrioma: Case series and management outcomes. 感染性卵巢子宫内膜瘤：病例系列和管理结果。

IF 2.5

Annals of the Academy of Medicine, Singapore Pub Date : 2025-02-25 DOI: 10.47102/annals-acadmedsg.2024282

Grace Ming Fen Chan, Rachel Jiayu Lee, Ma Li, Jing Lin Jeslyn Wong

引用次数: 0

Navigating health challenges: Singapore's National University Health System's approach to child and family well-being. 应对健康挑战：新加坡国立大学卫生系统对儿童和家庭福祉的方法。

IF 2.5

Annals of the Academy of Medicine, Singapore Pub Date : 2025-02-25 DOI: 10.47102/annals-acadmedsg.2024183

Yee Keow Chiong, Wanyun Lin, Logan Manikam, Wei Ying Hai, Mat Shah, Jeannie Chiam, Mahesh Choolani, Yung Seng Lee

引用次数: 0

Navigating the risks of contrast extravasation in CT scans: A 3-year study of 26,544 automated power injector cases. 引导CT扫描造影剂外渗的风险：26544例自动动力注射器病例的3年研究。

IF 2.5

Annals of the Academy of Medicine, Singapore Pub Date : 2025-02-25 DOI: 10.47102/annals-acadmedsg.2024270

Hui Seong Teh, Sivasubramanian Srinivasan, Rahul Lohan, Mark Tan Ming Loong

引用次数: 0