Journal of Experimental Psychology最新文献

Efficacy and Safety of Uninterrupted Periprocedural Edoxaban in Patients Undergoing Catheter Ablation for Atrial Fibrillation　- The Prospective KYU-RABLE Study. 心房颤动导管消融术患者围手术期不间断服用埃多沙班的有效性和安全性--前瞻性 KYU-RABLE 研究。

IF 3.1

Journal of Experimental Psychology Pub Date : 2019-09-25 Epub Date: 2019-09-12 DOI: 10.1253/circj.CJ-19-0535

Naohiko Takahashi, Yasushi Mukai, Tetsuya Kimura, Keita Yamaguchi, Takuyuki Matsumoto, Hideki Origasa, Ken Okumura

{"title":"Efficacy and Safety of Uninterrupted Periprocedural Edoxaban in Patients Undergoing Catheter Ablation for Atrial Fibrillation　- The Prospective KYU-RABLE Study.","authors":"Naohiko Takahashi, Yasushi Mukai, Tetsuya Kimura, Keita Yamaguchi, Takuyuki Matsumoto, Hideki Origasa, Ken Okumura","doi":"10.1253/circj.CJ-19-0535","DOIUrl":"10.1253/circj.CJ-19-0535","url":null,"abstract":"Background: The KYU-RABLE study, a prospective, multicenter, single-arm interventional study, evaluated the efficacy and safety of uninterrupted oral edoxaban in patients undergoing catheter ablation (CA) for atrial fibrillation (AF).Methods and results: We enrolled patients with AF from 23 centers in Japan. Edoxaban 60 mg (30 mg in patients indicated for dose adjustment) was administered uninterrupted, once daily in the morning for ≥4 weeks before CA and 4 weeks ±7 days after CA with one dose delayed on the procedural day. The primary endpoint was a composite of thromboembolism and major bleeding during 4 weeks from the procedural day. Among the 513 eligible patients who underwent CA, 63.5% received edoxaban 60 mg/day and 36.1% received 30 mg/day. For the primary endpoint, no thromboembolism and 1 major bleeding event (0.2%, cardiac tamponade) were observed. The plasma edoxaban concentration decreased depending on the time from the last administration to the CA procedure. However, plasma levels of coagulative biomarkers were within appropriate ranges regardless of the interval from the last administration of edoxaban.Conclusions: The present study provided evidence of the efficacy and safety of uninterrupted edoxaban administered once daily in the morning, with one dose delayed on procedural day, in patients with AF undergoing CA. Edoxaban was associated with a low risk of periprocedural thromboembolic and bleeding complications.","PeriodicalId":50196,"journal":{"name":"Journal of Experimental Psychology","volume":"83 1","pages":"2017-2024"},"PeriodicalIF":3.1,"publicationDate":"2019-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80092048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Models of health behaviour predict intention to use long acting reversible contraception use. 健康行为模型预测使用长效可逆避孕药的意向。

Journal of Experimental Psychology Pub Date : 2016-11-18 DOI: 10.1177/1745505716678231

Gareth Roderique-Davies, Christine McKnight, Bev Jonn, Susan Faulkner, Deborah Lancastle

引用次数: 0

Internal Consistency and Convergent Validity of the Portuguese Versions of the Global Appraisal of Individual Needs-Initial and Short Screener: Validity of the Portuguese GAIN-I and SS. 葡萄牙语版个人需求全面评估初筛和短筛的内部一致性和收敛有效性：葡萄牙语 GAIN-I 和 SS.

IF 1.5

Journal of Experimental Psychology Pub Date : 2016-10-01 DOI: 10.1097/JAN.0000000000000143

Heloísa Garcia Claro, Márcia Aparecida Ferreira de Oliveira, Ivan Filipe de Almeida Lopes Fernandes, Janet C Titus, Rosana Ribeiro Tarifa, Thais Fernandes Rojas, Paula Hayasi Pinho

{"title":"Internal Consistency and Convergent Validity of the Portuguese Versions of the Global Appraisal of Individual Needs-Initial and Short Screener: Validity of the Portuguese GAIN-I and SS.","authors":"Heloísa Garcia Claro, Márcia Aparecida Ferreira de Oliveira, Ivan Filipe de Almeida Lopes Fernandes, Janet C Titus, Rosana Ribeiro Tarifa, Thais Fernandes Rojas, Paula Hayasi Pinho","doi":"10.1097/JAN.0000000000000143","DOIUrl":"10.1097/JAN.0000000000000143","url":null,"abstract":"The goal of this article is to present evidence on the internal consistency and convergent validity of the Brazilian Portuguese versions of the Global Appraisal of Individual Needs-\"Initial\" and \"Short Screener\" versions.Methods: One hundred sixty-eight individuals from an inpatient service and/or a community-based outpatient service located in São Paulo were interviewed using the Brazilian Portuguese versions of the instruments. The internal consistency of the instruments scales was computed, along with evidence for the convergent validity between corresponding subscales of the Initial and Short Screener instruments.Results: Cronbach's alpha values for both instruments' total scale scores were greater than .7. The Short Screener scales showed strong-to-moderate correlations with corresponding subscales of the Initial. The General Individual Severity Scale from the Initial and Total Disorder Screener from the Short Screener have convergent validity with each other (ρ = 0.801).Conclusions: The Brazilian Portuguese instrument scales showed evidence for internal consistency and convergent validity performing similarly to the American English versions.","PeriodicalId":50196,"journal":{"name":"Journal of Experimental Psychology","volume":"73 1","pages":"241-246"},"PeriodicalIF":1.5,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80036810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

p21 induction plays a dual role in anti-cancer activity of ursolic acid. p21 诱导在熊果酸的抗癌活性中发挥着双重作用。

IF 3.2

Journal of Experimental Psychology Pub Date : 2016-03-01 Epub Date: 2015-11-17 DOI: 10.1177/1535370215616195

Xudong Zhang, Xinhua Song, Shutao Yin, Chong Zhao, Lihong Fan, Hongbo Hu

{"title":"p21 induction plays a dual role in anti-cancer activity of ursolic acid.","authors":"Xudong Zhang, Xinhua Song, Shutao Yin, Chong Zhao, Lihong Fan, Hongbo Hu","doi":"10.1177/1535370215616195","DOIUrl":"10.1177/1535370215616195","url":null,"abstract":"Previous studies have shown that induction of G1 arrest and apoptosis by ursolic acid is associated with up-regulation of cyclin-dependent kinase inhibitor (CDKI) protein p21 in multiple types of cancer cells. However, the functional role of p21 induction in G1 cell cycle arrest and apoptosis, and the mechanisms of p21 induction by ursolic acid have not been critically addressed. In the current study, we demonstrated that p21 played a mediator role in G1 cell cycle arrest by ursolic acid, whereas p21-mediated up-regulation of Mcl-1 compromised apoptotic effect of ursolic acid. These results suggest that p21 induction plays a dual role in the anti-cancer activity of ursolic acid in terms of cell cycle and apoptosis regulation. p21 induction by ursolic acid was attributed to p53 transcriptional activation. Moreover, we found that ursolic acid was able to inhibit murine double minute-2 protein (MDM2) and T-LAK cell-originated protein kinase (TOPK), the two negative regulator of p53, which in turn contributed to ursolic acid-induced p53 activation. Our findings provided novel insights into understanding of the mechanisms involved in cell cycle arrest and apoptosis induction in response to ursolic acid exposure. ","PeriodicalId":50196,"journal":{"name":"Journal of Experimental Psychology","volume":"92 1","pages":"501-8"},"PeriodicalIF":3.2,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1535370215616195","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79995925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20

Brain Potentials as Indices of Orthographic and Phonological Interaction During word Matching 脑电位作为单词匹配过程中正字法和音系相互作用的指标

Journal of Experimental Psychology Pub Date : 1987-01-01 DOI: 10.1037/0278-7393.13.1.76

A. Kramer, E. Donchin

引用次数: 57

Attention and the detection of signals. 注意和检测信号。

Journal of Experimental Psychology Pub Date : 1980-06-01

M I Posner, C R Snyder, B J Davidson

{"title":"Attention and the detection of signals.","authors":"M I Posner, C R Snyder, B J Davidson","doi":"","DOIUrl":"","url":null,"abstract":"Detection of a visual signal requires information to reach a system capable of eliciting arbitrary responses required by the experimenter. Detection latencies are reduced when subjects receive a cue that indicates where in the visual field the signal will occur. This shift in efficiency appears to be due to an alignment (orienting) of the central attentional system with the pathways to be activated by the visual input. It would also be possible to describe these results as being due to a reduced criterion at the expected target position. However, this description ignores important constraints about the way in which expectancy improves performance. First, when subjects are cued on each trial, they show stronger expectancy effects than when a probable position is held constant for a block, indicating the active nature of the expectancy. Second, while information on spatial position improves performance, information on the form of the stimulus does not. Third, expectancy may lead to improvements in latency without a reduction in accuracy. Fourth, there appears to be little ability to lower the criterion at two positions that are not spatially contiguous. A framework involving the employment of a limited-capacity attentional mechanism seems to capture these constraints better than the more general language of criterion setting. Using this framework, we find that attention shifts are not closely related to the saccadic eye movement system. For luminance detection the retina appears to be equipotential with respect to attention shifts, since costs to unexpected stimuli are similar whether foveal or peripheral. These results appear to provide an important model system for the study of the relationship between attention and the structure of the visual system.","PeriodicalId":50196,"journal":{"name":"Journal of Experimental Psychology","volume":"109 2","pages":"160-74"},"PeriodicalIF":0.0,"publicationDate":"1980-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18393748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Persistence: the role of partial reinforcement in psychotherapy. 坚持:部分强化在心理治疗中的作用。

Journal of Experimental Psychology Pub Date : 1980-06-01

J R Nation, D J Woods

引用次数: 0

Attention and the detection of signals. 注意和检测信号。

Journal of Experimental Psychology Pub Date : 1980-06-01 DOI: 10.1037/0096-3445.109.2.160

M. Posner, C. R. Snyder, B. J. Davidson

{"title":"Attention and the detection of signals.","authors":"M. Posner, C. R. Snyder, B. J. Davidson","doi":"10.1037/0096-3445.109.2.160","DOIUrl":"https://doi.org/10.1037/0096-3445.109.2.160","url":null,"abstract":"Detection of a visual signal requires information to reach a system capable of eliciting arbitrary responses required by the experimenter. Detection latencies are reduced when subjects receive a cue that indicates where in the visual field the signal will occur. This shift in efficiency appears to be due to an alignment (orienting) of the central attentional system with the pathways to be activated by the visual input. It would also be possible to describe these results as being due to a reduced criterion at the expected target position. However, this description ignores important constraints about the way in which expectancy improves performance. First, when subjects are cued on each trial, they show stronger expectancy effects than when a probable position is held constant for a block, indicating the active nature of the expectancy. Second, while information on spatial position improves performance, information on the form of the stimulus does not. Third, expectancy may lead to improvements in latency without a reduction in accuracy. Fourth, there appears to be little ability to lower the criterion at two positions that are not spatially contiguous. A framework involving the employment of a limited-capacity attentional mechanism seems to capture these constraints better than the more general language of criterion setting. Using this framework, we find that attention shifts are not closely related to the saccadic eye movement system. For luminance detection the retina appears to be equipotential with respect to attention shifts, since costs to unexpected stimuli are similar whether foveal or peripheral. These results appear to provide an important model system for the study of the relationship between attention and the structure of the visual system.","PeriodicalId":50196,"journal":{"name":"Journal of Experimental Psychology","volume":"109 2 1","pages":"160-74"},"PeriodicalIF":0.0,"publicationDate":"1980-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1037/0096-3445.109.2.160","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"58003692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3722

Persistence: the role of partial reinforcement in psychotherapy. 坚持:部分强化在心理治疗中的作用。

Journal of Experimental Psychology Pub Date : 1980-06-01 DOI: 10.1037/0096-3445.109.2.175

J. Nation, Donald J. Woods

{"title":"Persistence: the role of partial reinforcement in psychotherapy.","authors":"J. Nation, Donald J. Woods","doi":"10.1037/0096-3445.109.2.175","DOIUrl":"https://doi.org/10.1037/0096-3445.109.2.175","url":null,"abstract":"Persistence, which refers to the ability of a learned behavior to survive protracted nonreinforcement (extinction), has been an overlooked dimension of clinical intervention. While persistence of newly acquired coping behavior is desired (and possibly assumed) by all psychotherapeutic procedures, few treatment programs possess features that operate to sustain responding in the face of a nonsupportive, nonreinforcing environment. The present article presents a treatment strategy designed to foster persistence based on the laboratory findings that partial reinforcement schedules produce greater resistance to extinction than continuous reinforcement schedules--a phenomenon referred to as the partial reinforcement extinction effect. The two major theories of persistence (Amsel's general theory of persistence and Capaldi's sequential theory) are discussed, and the basic principles of these models are extended to a number of therapeutic modalities including depression therapies, systemic desensitization, assertiveness training, and aversion therapy. In addition, procedural considerations including generalized and discriminated persistence are discussed.","PeriodicalId":50196,"journal":{"name":"Journal of Experimental Psychology","volume":"109 2 1","pages":"175-207"},"PeriodicalIF":0.0,"publicationDate":"1980-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1037/0096-3445.109.2.175","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"58003715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 40

Facilitating Effects of a Safe Platform on Two-Way Avoidance Learning. 安全平台对双向回避学习的促进作用。

Journal of Experimental Psychology Pub Date : 1978-01-01 DOI: 10.1037//0097-7403.4.1.83

Heidar A. Modaresi

引用次数: 20