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The American Journal of Dermatopathology最新文献

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Bullous Dermatosis on the Whole Body: Challenge 全身大疱性皮肤病：挑战
The American Journal of Dermatopathology Pub Date : 2024-05-01 DOI: 10.1097/dad.0000000000002692
Uiju Cho, Jihae Lee, C. Yoo
{"title":"Bullous Dermatosis on the Whole Body: Challenge","authors":"Uiju Cho, Jihae Lee, C. Yoo","doi":"10.1097/dad.0000000000002692","DOIUrl":"https://doi.org/10.1097/dad.0000000000002692","url":null,"abstract":"","PeriodicalId":501833,"journal":{"name":"The American Journal of Dermatopathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141026948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Soft Pink Plaques at the Site of Breast Cancer Vaccination: Answer 乳腺癌疫苗接种点的粉红色软牌匾：答案
The American Journal of Dermatopathology Pub Date : 2024-05-01 DOI: 10.1097/dad.0000000000002683
Katherine L Wang, Matthew R. Hall, S. Chumsri, O. Sokumbi
{"title":"Soft Pink Plaques at the Site of Breast Cancer Vaccination: Answer","authors":"Katherine L Wang, Matthew R. Hall, S. Chumsri, O. Sokumbi","doi":"10.1097/dad.0000000000002683","DOIUrl":"https://doi.org/10.1097/dad.0000000000002683","url":null,"abstract":"","PeriodicalId":501833,"journal":{"name":"The American Journal of Dermatopathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141032335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Small Vesicles and Tense Bullae on Face, Neck, and Upper Trunk: Answer 面部、颈部和躯干上部出现小囊泡和紧张性囊泡：答案
The American Journal of Dermatopathology Pub Date : 2024-05-01 DOI: 10.1097/dad.0000000000002669
Jill Stachowski, James Strassner, Christopher G. Bazewicz, Thomas N. Helm
{"title":"Small Vesicles and Tense Bullae on Face, Neck, and Upper Trunk: Answer","authors":"Jill Stachowski, James Strassner, Christopher G. Bazewicz, Thomas N. Helm","doi":"10.1097/dad.0000000000002669","DOIUrl":"https://doi.org/10.1097/dad.0000000000002669","url":null,"abstract":"","PeriodicalId":501833,"journal":{"name":"The American Journal of Dermatopathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141032304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Follicular (Infundibular-Tricholemmal) Squamous Cell Carcinoma: A New WHO Entity. Clinicopathological Features in 103 Cases, Including Follow-Up and Implications for Patient Management. 滤泡（泪囊-三孔）鳞状细胞癌：世界卫生组织的一个新实体。103 例病例的临床病理特征，包括随访和对患者管理的影响。
The American Journal of Dermatopathology Pub Date : 2024-04-23 DOI: 10.1097/dad.0000000000002713
Richard A Carr, James Wiggins, David N Slater
{"title":"Follicular (Infundibular-Tricholemmal) Squamous Cell Carcinoma: A New WHO Entity. Clinicopathological Features in 103 Cases, Including Follow-Up and Implications for Patient Management.","authors":"Richard A Carr, James Wiggins, David N Slater","doi":"10.1097/dad.0000000000002713","DOIUrl":"https://doi.org/10.1097/dad.0000000000002713","url":null,"abstract":"Cutaneous follicular (infundibular-tricholemmal) squamous cell carcinoma (FSCC) is a new World Health Organization entity. We present the largest series of published cases, summarizing clinical data, diagnostic criteria, differential diagnosis, and implications for patient management.","PeriodicalId":501833,"journal":{"name":"The American Journal of Dermatopathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140637318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Richter Syndrome Presenting as Subcutaneous Nodules and a Dermal Plaque. 表现为皮下结节和皮肤斑块的里克特综合征
The American Journal of Dermatopathology Pub Date : 2024-04-23 DOI: 10.1097/dad.0000000000002720
Melissa Nickles, Samantha Hunt, Saul Turcios-Escobar, Amaara Babwah, Nisreen Mobayed, Carlos Murga-Zamalloa, Michelle Bain, John Quigley, Paul Rubinstein, Carlos Galvez
{"title":"Richter Syndrome Presenting as Subcutaneous Nodules and a Dermal Plaque.","authors":"Melissa Nickles, Samantha Hunt, Saul Turcios-Escobar, Amaara Babwah, Nisreen Mobayed, Carlos Murga-Zamalloa, Michelle Bain, John Quigley, Paul Rubinstein, Carlos Galvez","doi":"10.1097/dad.0000000000002720","DOIUrl":"https://doi.org/10.1097/dad.0000000000002720","url":null,"abstract":"Richter syndrome (RS) describes a phenomenon in which a patient with chronic lymphocytic leukemia (CLL) develops an aggressive lymphoma, most commonly diffuse large B-cell lymphoma (DLBCL). Reports of cutaneous RS remain exceedingly rare. We report a 61-year-old woman with relapsed/refractory CLL presenting with several subcutaneous nodules on her arms and legs and a single dermal plaque on her abdomen. Skin biopsy revealed a diagnosis of DLBCL, ABC-type, and her clinical status rapidly deteriorated following diagnosis. We review the variety of clinical presentations of cutaneous RS, its association with CLL, risk factors for RS development in CLL patients, and the distinctive histopathologic and immunophenotypic features of DLBCL. We hope to highlight the importance of prompt skin biopsy in patients with CLL presenting with progressive skin lesions and increase awareness of this aggressive clinical syndrome.","PeriodicalId":501833,"journal":{"name":"The American Journal of Dermatopathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140637208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combined Melanocytic Nevus and Nevus Sebaceus: A Case Series and Review of the Literature. 合并黑色素细胞痣和眼睑痣：病例系列和文献综述。
The American Journal of Dermatopathology Pub Date : 2024-04-23 DOI: 10.1097/dad.0000000000002710
Liesl M Schroedl, Jenna J Lullo, Arlene M Ruiz de Luzuriaga, Christopher R Shea
{"title":"Combined Melanocytic Nevus and Nevus Sebaceus: A Case Series and Review of the Literature.","authors":"Liesl M Schroedl, Jenna J Lullo, Arlene M Ruiz de Luzuriaga, Christopher R Shea","doi":"10.1097/dad.0000000000002710","DOIUrl":"https://doi.org/10.1097/dad.0000000000002710","url":null,"abstract":"Nevus sebaceus is a rare congenital hamartoma with clinical and histopathological features that change with puberty. It has been associated with a number of secondary neoplasms, most of which are thought to derive from follicular germ cells. In this article, the authors describe a total of 3 cases of combined melanocytic nevus and nevus sebaceus to highlight this rare finding.","PeriodicalId":501833,"journal":{"name":"The American Journal of Dermatopathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140637198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blau Syndrome With Delayed Cutaneous Manifestations: A Case Report. 伴有延迟性皮肤表现的布劳综合征：病例报告
The American Journal of Dermatopathology Pub Date : 2024-04-23 DOI: 10.1097/dad.0000000000002715
Elnaz Panah, Erin Garfield, Zisansha Zahirsha, Aaron Muhlbauer, Eden Lake, Jodi Speiser
{"title":"Blau Syndrome With Delayed Cutaneous Manifestations: A Case Report.","authors":"Elnaz Panah, Erin Garfield, Zisansha Zahirsha, Aaron Muhlbauer, Eden Lake, Jodi Speiser","doi":"10.1097/dad.0000000000002715","DOIUrl":"https://doi.org/10.1097/dad.0000000000002715","url":null,"abstract":"Blau syndrome is a rare familial autoinflammatory disorder characterized by the triad of granulomatous dermatitis, polyarthritis, and uveitis. Blau syndrome exhibits an autosomal dominant inheritance pattern and can be caused by a gain-of-function mutation in nucleotide-binding oligomerization domain 2 (NOD2), a member of the NOD-like receptor family of pattern recognition receptors. Mutations in NOD2 cause upregulation of inflammatory cytokines and resultant autoinflammation. Because of the rarity of this condition and early onset of symptoms, Blau syndrome may be misdiagnosed as juvenile idiopathic arthritis. We present a case of a 37-year-old male patient with a long-documented history of juvenile idiopathic arthritis and uveitis, who developed an asymptomatic eruption of pink papules on the trunk and upper extremities. A biopsy demonstrated noncaseating, well-formed dermal granulomas with relatively sparse lymphocytic inflammation and Langerhans-type giant cells. Genetic testing confirmed a mutation in NOD2. Based on the patient's clinical history, histologic findings, genetic testing, the diagnosis of Blau syndrome was made.","PeriodicalId":501833,"journal":{"name":"The American Journal of Dermatopathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140637079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Junctional Epidermolysis Bullosa Linked to Homozygous Mutation in LAMC2 Gene: A Case Report With Eosinophil-Rich Inflammatory Infiltrate. 与 LAMC2 基因同基因突变有关的交界性表皮松解症：一例伴有嗜酸性粒细胞炎性浸润的病例报告。
The American Journal of Dermatopathology Pub Date : 2024-04-23 DOI: 10.1097/dad.0000000000002714
Şule Haskoloğlu, Gökcan Öztürk, Nazlı Deveci Demirbaş, Can Akal, Candan İslamoğlu, Kübra Baskın, Aylin Heper, Ömer Erdeve, Serdar Ceylaner, Figen Doğu, Aydan İkincioğulları
{"title":"Junctional Epidermolysis Bullosa Linked to Homozygous Mutation in LAMC2 Gene: A Case Report With Eosinophil-Rich Inflammatory Infiltrate.","authors":"Şule Haskoloğlu, Gökcan Öztürk, Nazlı Deveci Demirbaş, Can Akal, Candan İslamoğlu, Kübra Baskın, Aylin Heper, Ömer Erdeve, Serdar Ceylaner, Figen Doğu, Aydan İkincioğulları","doi":"10.1097/dad.0000000000002714","DOIUrl":"https://doi.org/10.1097/dad.0000000000002714","url":null,"abstract":"Junctional epidermolysis bullosa (JEB) is a rare, incurable, devastating, and mostly fatal congenital genetic disorder characterized by painful blistering of the skin and mucous membranes in response to minor trauma or pressure. JEB is classified roughly into 2 subtypes: JEB-Herlitz is caused by mutations on genes encoding laminin-332. The authors present a patient consulted with a suspicion of primary immunodeficiency due to skin sores that started at the age of 1 month and a history of 3 siblings who died with similar sores, who was diagnosed with JEB-Herlitz after detecting a homozygous LAMC2 gene mutation in WES analysis. Microscopic evaluation of hematoxylin and eosin-stained sections showed vesicle formation with subepidermal separation, which is accompanied by striking neutrophil and eosinophil leukocyte infiltration both in the vesicle and papillary dermis (eosinophil-rich inflammatory infiltrate). Such a histopathological finding has been rarely reported in this condition.","PeriodicalId":501833,"journal":{"name":"The American Journal of Dermatopathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140637083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cutaneous Metaplastic Synovial Cyst Presenting as a Cutaneous Horn. 表现为皮肤角的皮肤变性滑膜囊肿
The American Journal of Dermatopathology Pub Date : 2024-04-23 DOI: 10.1097/dad.0000000000002725
Yao Zhang, Yibin Zeng, Haibin Cai
{"title":"Cutaneous Metaplastic Synovial Cyst Presenting as a Cutaneous Horn.","authors":"Yao Zhang, Yibin Zeng, Haibin Cai","doi":"10.1097/dad.0000000000002725","DOIUrl":"https://doi.org/10.1097/dad.0000000000002725","url":null,"abstract":"","PeriodicalId":501833,"journal":{"name":"The American Journal of Dermatopathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140667239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Apocrine Hidrocystoma of the Nail: A Unique Case. 指甲分泌性脂囊肿：一个独特的病例
The American Journal of Dermatopathology Pub Date : 2024-04-23 DOI: 10.1097/dad.0000000000002729
Haneen Salah, Juanita Duran, Mark A Russell, Alejandro A Gru
{"title":"Apocrine Hidrocystoma of the Nail: A Unique Case.","authors":"Haneen Salah, Juanita Duran, Mark A Russell, Alejandro A Gru","doi":"10.1097/dad.0000000000002729","DOIUrl":"https://doi.org/10.1097/dad.0000000000002729","url":null,"abstract":"Apocrine hidrocystomas are benign, cystic neoplastic lesions resulting from the apocrine secretory component of the sweat gland. They most commonly occur on the head and neck, with predilection to the periorbital area. Less frequent sites include the axilla, nipple, external auditory canal, foreskin, conjunctiva, lower lip, and fingers, among others. The authors report a unique case of a nail bed hidrocystoma in a 55-year-old woman, a site not previously described.","PeriodicalId":501833,"journal":{"name":"The American Journal of Dermatopathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140637317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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