Mugda Medical College Journal最新文献

{"title":"Modified D2 Gastrectomy operation in Gastric Cancer Patients and Outcome","authors":"Md Mosharraf Hossain, Junaidur Rahman, Tawhida Khandaker","doi":"10.3329/mumcj.v7i1.73967","DOIUrl":"https://doi.org/10.3329/mumcj.v7i1.73967","url":null,"abstract":"Gastric cancer remains the fifth most commonly diagnosed cancer and the third leading cause of cancer-related deaths worldwide. In 2018, there were an estimated 1,033,701 newly diagnosed cases and 782,685 related deaths. The aim of this study was to evaluate outcome of modified D2 gastrectomy operation in gastric cancer patients with or without comorbidities. This prospective observational study was conducted at the Department of Surgical Oncology, National Institute of Cancer Research and Hospital, Mohakhali, Dhaka, from July 2019 to March 2021. A total of 53 patients were included in the study. The outcome of the surgery was assessed by monitoring postoperative complications for a period of 30 days. Statistical analysis was performed using SPSS (Statistical Package for the Social Sciences) version 28. Prior to the commencement of the study, the research protocol was approved by the Research Review Committee of the Department of Surgical Oncology and the Ethical Committee of the National Institute of Cancer Research and Hospital, Dhaka. There was no significant association observed between postoperative complications of modified D2 gastrectomy and patients’ age, gender, or smoking status. Among the 53 patients, the highest proportion (92.45%) experienced anorexia, followed by vomiting (81.13%), and approximately 71.69% had dyspepsia. Among the patients, 52.83% had diabetes mellitus (DM) and 45.28% had hypertension (HTN). Patients with gastric cancer and DM were found to be more susceptible to developing wound infections. Based on the analysis of the study results, it can be concluded that modified D2 gastrectomy is a safe procedure that yields acceptable postoperative outcomes for the treatment of gastric cancer in a tertiary care center.\u0000Mugda Med Coll J. 2024; 7(1): 31-35","PeriodicalId":499854,"journal":{"name":"Mugda Medical College Journal","volume":" 1160","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141669043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Neutrophil-Lymphocyte Ratio as Inflammatory Marker in Chronic Kidney Disease Stage 3 and 4","authors":"Md Aminul Islam Sumon, Md Nazrul Islam, Md Farhad Hasan Chowdhury, Palash Kumar Deb nath, Muhammad Saiful Ahsan Rana, Jyoti Vaskar Saha, Gul Jannat, Sheikh Imran Hoseen, Mst Nazmun Naher","doi":"10.3329/mumcj.v7i1.73955","DOIUrl":"https://doi.org/10.3329/mumcj.v7i1.73955","url":null,"abstract":"Chronic kidney disease (CKD) is a worldwide health problem because of the significant morbidity and mortality which is mostly due to chronic inflammation and proteinuria. Early detection of inflammation and its proper management can prevent further CKD progression and complications. This study aims to observe the association of neutrophil-lymphocyte ratio (NLR) with inflammatory markers in chronic kidney disease stage 3 and 4. In this study, a total of 100 adult patients of CKD stage-3 and 4 were included as study subjects and patient with acute illness, known case of malignancy, cardiovascular and cerebrovascular disease were excluded from the study. From each patient all the relevant history, clinical and laboratory findings were recorded in the data collection sheet. Study subjects were divided into two groups according to NLR value; those who have NLR 0- 3 were in group normal NLR and subjects with NLR >3 in group high NLR. Then markers of inflammation ESR, CRP and serum albumin were compared between these groups. Statistical analysis was done by Statistical Package for Social Science (SPSS) version 22.0. The mean ESR of male and female patients was higher in high NLR subjects than normal NLR subjects. The mean CRP was higher in high NLR subjects than normal NLR subjects. The mean serum albumin was lower in high NLR subjects than normal NLR subjects. The difference of mean ESR, CRP was statistically significant between high NLR and normal NLR subjects but difference of mean serum albumin was not statistically significant. The study findings suggest that high NLR is significantly associated with of inflammatory markers-ESR, CRP. Hence, it can be concluded that NLR could be used as an indicator of inflammation in CKD.\u0000Mugda Med Coll J. 2024; 7(1): 4-8","PeriodicalId":499854,"journal":{"name":"Mugda Medical College Journal","volume":" 668","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141669538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Managing Substance Use Disorders and Addiction: How to Integrate Professionalism and Ethics with the Complexity of Diagnosis and Therapy","authors":"A. S. M. Nurunnabi, Saifun Nahar, N. Akhter, Muhammad Abdul Kayum Shaikh, Md Ferdous Rahman, Mohammad Tipu Sultan","doi":"10.3329/mumcj.v7i1.73977","DOIUrl":"https://doi.org/10.3329/mumcj.v7i1.73977","url":null,"abstract":"Physicians and other healthcare staff who work with the patients having substance use disorders (SUDs) and addiction have to deal with different and complex scenario invariably in comparison to other healthcare providers dealing with regular medical services sought by the patients. Hence, the unconventional nature of practice regarding patients of SUDs and addiction and the diverse range of backgrounds among substance use workers, e.g., psychiatrist, general physician, nurse, psychotherapist, counsellor, social worker, and public health specialist highlights the universal relevance of being more professional and more ethical in practice. They are expected to demonstrate a variety of ethical and professional competences to safeguard themselves and others involved. Clinical team engaged in such activities requires specific ethical training that can help them face specific ethical dilemmas and guide through deeper consideration of those pressing and complex issues, using specific framework, professional guidelines, or institutional management approaches. Professional societies and accrediting institutions should apply their authority to establish practice standards, competencies, regulatory procedures, and codes of ethics to help guide practice and protect public trust and confidence. For the team involved in practice, it is important to become familiar with and adhere to the principles and values that define professionalism and ethical conduct in care for patients suffering from SUDs and addiction. The review paper aims to examine the intersection of professionalism and ethics with the complexity of diagnosis and therapy in this specific area of practice. Besides, some frameworks will be highlighted which may help healthcare providers to foster ethical decision making. It is also a modest effort to show some new insights for improving the quality of care in addiction and mental health by the professional team and healthcare organization from both clinical and operational viewpoint.\u0000Mugda Med Coll J. 2024; 7(1): 42-47","PeriodicalId":499854,"journal":{"name":"Mugda Medical College Journal","volume":" 747","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141669376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Treatment Outcome of Ganciclovir Ophthalmic Gel and Moxifloxacin Eye Drop in Acute Adenoviral Keratoconjunctivitis","authors":"Fareya Nadir, Niloy Kumar Basak, Md Robiul Islam, E. H. Rahat, Abdullah Al Mamun, Mohammad Ashaduzzaman, M. Saifullah, Mohammad Rashedul Hasan","doi":"10.3329/mumcj.v7i1.73958","DOIUrl":"https://doi.org/10.3329/mumcj.v7i1.73958","url":null,"abstract":"Adenoviral ophthalmic infection is a self-limiting, highly contagious, very frequent infectious process. It can present in three acute clinical forms: nonspecific acute follicular conjunctivitis, pharyngo-conjunctival fever and epidemic keratoconjunctivitis. This study aims to assess and compare the efficacy of 0.15% ganciclovir gel with Moxifloxacin eye drop in the treatment of acute adenoviral keratoconjunctivitis.This longitudinal prospective study was conducted among 40 patients of acute adenoviral keratoconjuctivitis attending in the cornea clinic of National Institute of Ophthalmology & Hospital (NIOH), Dhaka, Bangladesh. They were randomly divided into two groups: group-I (study group) with 20 patients who used 0.15% ganciclovir gel and group-ii (control group) with 20 patients who used artificial tear and 0.5% moxifloxacin eye drop. Diagnosis was confirmed by expert cornea specialist by methodical ophthalmic examination. They were followed-up on 1,2,4 and 6 weekly. Mean score of symptoms and signs were calculated in every follow-up and compared between two groups. Unpaired t test and chi square test were done in applicable cases with statistical significance p<0.05. This study showed that in study group mean age of the respondents were 36.4±9.59 years and in control group 37±11.02 years. Most of them were male (82.5%). In study group, mean score of symptoms at the beginning of the study was 1.4. It was 1.14, 0.64, 0.20 and 0.04 after1,2,4,6 weeks respectively after starting treatment and in control group mean score of symptoms at the beginning of the study was 1.48. It was 1.46, 1.125,0.59 and 0.23 after1,2,4,6weeks respectively after starting treatment. A trend towards better response was observed in the treatment group and the difference was statically significant. The mean score of signs after starting treatment in group-iwas 1.8.It was 1.35, 0.775, 0.30 and 0.175 after ,2,4,6weeks respectively and in group-ii, mean score of signs at the beginning of the study was 1.675. It was 1.725,1.35,0.725 and 0.300 after 1,2,4,6 weeks respectively after starting treatment. A trend towards improved sings were observed in the study group and the difference was statistically significant at 1 week (p=0.0283), 2 week (p= 0.0003), 4 week (p=0.0016) except 6 week (p=0.1524). At 6th week of treatment improvement of signs occur but not statistically significant because of persistence of some corneal lesion. The significant symptomatic relief and clinical improvement was found in the study group treated with Ganciclovir ophthalmic gel suggesting an effective method for treatment of acute adenoviral keratoconjunctivitis.\u0000Mugda Med Coll J. 2024; 7(1): 9-13","PeriodicalId":499854,"journal":{"name":"Mugda Medical College Journal","volume":"110 40","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141667102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparison of Functional Endothelial Changes between Phacoemulsification with PCIOL and Manual Small Incision Cataract Surgery with PCIOL","authors":"Mohammad Mahbubul Hasan, Natasha Kajmina, Hasiba Begum","doi":"10.3329/mumcj.v7i1.73960","DOIUrl":"https://doi.org/10.3329/mumcj.v7i1.73960","url":null,"abstract":"Intraocular surgery e.g., cataract surgery with PCIOL implantation is one of the leading causes of corneal endothelial injury and change in the functionality of the cornea. This observational study was conducted in the Department of Ophthalmology of Combined Military Hospital (CMH), Dhaka Cantonment, Dhaka, Bangladesh, between January and July of 2016, to assess and compare functional changes in cornea (i.e., endothelial thickness) after phacoemulsification with posterior chamber intraocular lens (PCIOL) implantation and manual small incision cataract surgery (MSICS) with PCIOL implantation. A total of 80 patients of age-related cataract were randomly selected based on inclusion and exclusion criteria. All patients underwent complete ophthalmic evaluation pre- and post-operatively (at day 1, after 1 week and 3 months) specifically for observation of the endothelial changes in cornea. Specular microscopy was done to assess corneal endothelial change. The mean central corneal thickness was increased at day 1 (564.71±22.45μ vs. 555.10±40.57μ), after 1 week (539.43±22.16μ vs. 535.08±38.87μ) and 3 months (523.49±21.29μ vs. 520.05±33.68μ) after phacoemulsification and MSICS from their preoperative value (508.72±23.96μ vs. 503.62±32.06μ) respectively. However, the differences were not statistically significant between two groups (P>0.05). The mean percentage of central corneal thickness change at day1, after 1 week and after 3 months following cataract surgery were found 11.01±6.30% and 10.22±26.54% at day 1, 6.04±7.52% and 6.25±21.24% after 1 week, 2.90±11.14% and 3.26±5.05% after 3 months in phacoemulsification and MSICS cases respectively. However, no statistically significant difference was observed in percentage of central corneal thickness change of both groups (P>0.05). To summarize, an increased central corneal thickness was observed after phacoemulsification and SICS from their preoperative values.\u0000Mugda Med Coll J. 2024; 7(1): 14-18","PeriodicalId":499854,"journal":{"name":"Mugda Medical College Journal","volume":" 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141670316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ophthalmic Manifestations of Leukemia and Their Management","authors":"Kripadhan Chakroborty, Mohammad Mahbubul Hasan, Md Hasanuzzaman, Zakia Sultana, S. A. Khaleque","doi":"10.3329/mumcj.v7i1.73969","DOIUrl":"https://doi.org/10.3329/mumcj.v7i1.73969","url":null,"abstract":"Patients with leukemia often have ophthalmic manifestations. These occur either from direct infiltrations of neoplastic cells or from indirect or secondary causes. Nearly all ocular structures can be affected by leukemia. Sometimes, ophthalmic involvement can be the first sign of disease relapse. This review article aims to highlight different ocular manifestations of leukemia along with treatment. It involves studying the available material in textbooks, printed and online journals. As there is high prevalence of ocular findings in leukemia, it can be a standard practice that all leukemic patients should have screening by ocular examination. Awareness of the clinical spectrum of leukemic infiltration of ocular region is essential for rapid diagnosis, prompt initiation of treatment and better outcome. If prompt diagnosis and treatment can be done, worsening of vision may be minimized or prevented.\u0000Mugda Med Coll J. 2024; 7(1): 36-41","PeriodicalId":499854,"journal":{"name":"Mugda Medical College Journal","volume":"117 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141667674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endometrioid Carcinoma Four Years After Hysterectomy: A Rare Case Report","authors":"Riffat Rahim, Nahida Akter Hira, Rinita Banerjee","doi":"10.3329/mumcj.v7i1.73982","DOIUrl":"https://doi.org/10.3329/mumcj.v7i1.73982","url":null,"abstract":"It is quite a fascinating case as we have recently experienced in Mugda Medical College Hospital, a tertiary level teaching hospital in Dhaka, Bangladesh, that a woman was diagnosed and treated for endometrioid adenocarcinoma four years after her vaginal hysterectomy had been done. Our patient was presented with abdominal pain for nearly 2 weeks along with nausea, vomiting and generalized weakness. Ultrasound evaluation revealed a complex pelvic mass (8.6cm × 4.9cm). Chest x-ray revealed a left sided pleural effusion, while CT scan of the abdomen revealed heterogeneously enhancing complex pelvic mass and mild ascites. After a clinical correlation with all the pathological investigations, the patient was advised for a core biopsy. Ultrasonogram guided core biopsy was done. Histopathological examination showed a malignant ovarian epithelial tumor. Then she underwent an interventional or surgical procedure, which included an exploratory laparotomy, bilateral salpingo-oophorectomy with bilateral pelvic lymph node dissection and infracolic omentectomy done under general anesthesia. The final histopathological examination of the removed mass showed an endometrioid adenocarcinoma (Grade 2). Meanwhile, she was referred for radiation therapy (both vaginal brachytherapy and external pelvic radiation) after the patient had recovered from surgery. We will discuss this case as a part of our clinical interest and continuing education for our clinicians and residents.\u0000Mugda Med Coll J. 2024; 7(1): 53-55","PeriodicalId":499854,"journal":{"name":"Mugda Medical College Journal","volume":" 1289","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141669081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anthropometric Study of Correlation between the Selected Craniofacial Measurements with the Stature in Adult Bangladeshi Manipuri Males","authors":"Farhana Bashar, Mosa Shaheli Binte Hossain, Najnin Akhter, Samina Sharmeen, Md Mohiuddin Masum, S. Suma, Md Afzalur Rahman Rahman","doi":"10.3329/mumcj.v7i1.73962","DOIUrl":"https://doi.org/10.3329/mumcj.v7i1.73962","url":null,"abstract":"Cephalofacial anthropometry can be useful for racial identification, forensic scientist, physical anthropologist, genetic counsellors as well as reconstructive surgery for the purposes of identification of an individuals and understanding human physical variation, gender and ethnicity especially with facial recognition as a tool in recent advances in biometrics. Stature is one of the important criteria for personal identification which has a proportional biological relationship with every parts of the human body like head, face, trunk, extremities and vertebral column. In this study, our main goal is find out the correlation between the selected craniofacial measurements with the stature in Adult Bangladeshi Manipuri males. This cross-sectional study was carried out in 100 healthy adult males from March 2017 to February 2018 in the Department of Anatomy, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh. Descriptive statistics and testing of hypotheses were used for the analysis using SPSS software (version 22.0). Here non- significant positive correlations of the stature with the mandible height and significant positive correlations of the stature with mandible breadth was found. The Mean (±SD) of Mandible height (sto-gn) was 4.44 (±0.69), Mandible breadth (go-go) was 11.45 (±0.57). This study will be anticipated to provide baseline quantitative data on the linear craniofacial measurements and the stature of adult Bangladeshi Manipuri males. And using larger samples with non-contact measurement technique will help in defining craniofacial anthropometric profiling of the adult Bangladeshi Manipuri males.\u0000Mugda Med Coll J. 2024; 7(1): 19-25","PeriodicalId":499854,"journal":{"name":"Mugda Medical College Journal","volume":"123 44","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141667702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Healthy Diet Trends in Recent Years","authors":"Mahibun Nahar","doi":"10.3329/mumcj.v7i1.73906","DOIUrl":"https://doi.org/10.3329/mumcj.v7i1.73906","url":null,"abstract":"Abstract not available\u0000Mugda Med Coll J. 2024; 7(1): 1-3","PeriodicalId":499854,"journal":{"name":"Mugda Medical College Journal","volume":" 416","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141669546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ramsay Hunt Syndrome: A Rare Disease of Multiple Cranial Nerve Involvement","authors":"Md Abdullah Al Mamun, Md Rabiul Islam, Riashat Azim Majumder, Mowpiya Mondal, Md Moniruzzama, Md Rashid E Mahbub, Mohammad Ashaduzzaman","doi":"10.3329/mumcj.v7i1.73983","DOIUrl":"https://doi.org/10.3329/mumcj.v7i1.73983","url":null,"abstract":"Ramsay Hunt Syndrome (RHS) also known as herpes zoster oticus is a viral disease, a member of the human herpes virus family, is a late complication of varicella-zoster virus infection that results in inflammation of the geniculate ganglion of cranial nerve VII. Ramsay Hunt is a clinical diagnosis. The hallmark of the condition is multiple unilateral erythematous vesicles, which are distributed over the auricle and preceded by severe otalgia. If these symptoms are associated with facial nerve palsy, the condition is called RHS which is usually accompanied by vestibulocochlear abnormalities. Diagnosis is often missed or delayed, which can lead to an increased incidence of long-term complications. The condition is self-limiting, but treatment is targeted at decreasing the total duration of the illness as well as providing analgesia and preventing the complications that can occur. This activity reviews the role of the inter professional team in the diagnosis and treatment of RHS.\u0000Mugda Med Coll J. 2024; 7(1): 48-52","PeriodicalId":499854,"journal":{"name":"Mugda Medical College Journal","volume":" 521","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141669582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}