Medical Dosimetry最新文献

{"title":"Response to letter to the editor: Investigating the impact of RapidPlan on Ethos automated planning.","authors":"S A Yoganathan","doi":"10.1016/j.meddos.2026.04.003","DOIUrl":"https://doi.org/10.1016/j.meddos.2026.04.003","url":null,"abstract":"","PeriodicalId":49837,"journal":{"name":"Medical Dosimetry","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147943551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of a freely available Eclipse script for automatic calculation of EQD2 dose distribution in external beam radiotherapy.","authors":"Juan-Francisco Calvo-Ortega, Coral Laosa-Bello, Sandra Moragues-Femenía","doi":"10.1016/j.meddos.2026.03.014","DOIUrl":"https://doi.org/10.1016/j.meddos.2026.03.014","url":null,"abstract":"<p><p>To validate a script designed to streamline equivalent dose in 2 Gy fractions (EQD2) calculations for external beam radiotherapy. The VarianESAPI-EQD2Converter script for EQD2 calculation was evaluated for the Eclipse v. 16.1 treatment planning system. Seven anatomical sites were included (head and neck, lung, liver, breast, prostate, abdomen, and brain), and 3 cases per site were randomly selected from our clinical database. For each plan, the values of the D2%, D50% and D98% metrics of the planning target volume (PTV), and D2%, D50%, and D0.1cc of the organs-at-risk (OARs) were retrieved and converted into EQD2 values using the EQD2 formula (\"true values\"). Then, the script was executed for each plan following these 2 approaches: (1) the alpha-beta values of the PTV and OARs were simultaneously entered (approach 1); (2) only the external patient contour (\"body\") structure was considered, and the script was run several times by entering the alpha-beta values of the PTV and OARs each time. Validation of the script was performed by comparing the EQD2 values computed by the script for the Dx%/D0.1cc metrics with the respective true values. A 2-tailed t-test statistical analysis was done (alpha = 0.05). Nonstatistically significant differences were found between the 2 approaches, but unacceptably high differences (up to 57.5%) were found using approach 1. By contrast, low absolute differences (mostly < 0.5%) were found with approach 2. The VarianESAPI-EQD2Converter script with approach 2 is a reliable method to automate the EQD2 calculation process for Eclipse users.</p>","PeriodicalId":49837,"journal":{"name":"Medical Dosimetry","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147787386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of avoidance sectors on knowledge-based planning for esophageal cancer treatment","authors":"Vishruta Dumane Ph.D., D.A.B.R. ,&nbsp;Victoria Olsen B.S., C.M.D. ,&nbsp;Ting Jiang B.S., C.M.D. ,&nbsp;Tyler Hwang B.S., C.M.D. ,&nbsp;Regina Yu B.S., C.M.D. ,&nbsp;Maria P. Dimopoulos Ph.D., M.B.A., R.T.(T)(A.R.R.T.)","doi":"10.1016/j.meddos.2025.09.004","DOIUrl":"10.1016/j.meddos.2025.09.004","url":null,"abstract":"<div><div>To build a knowledge-based treatment planning model using RapidPlan for esophageal cancer in the upper, mid and lower thoracic sites while comparing the performance of the model with and without the use of avoidance sectors. Plans from 45 patients with esophageal tumors requiring treatment in the upper (8), middle (15) and lower (22) thoracic regions were selected for training. Prescribed dose ranged from 41.4Gy to 56Gy (1.8-2 Gy/fraction) with simultaneous integrated boost (SIB). Clinical plans were re-planned without the use of avoidance sectors. Plans with reduced V105%(cc) to the planning target volume (PTV) while meeting criteria for organs at risk (OARs) were chosen to build the model. The model was validated on 23 plans by comparing the clinical plan to the RapidPlan with and without the use of avoidance sectors. RapidPlan without avoidance sectors reduced the V105%(cc) by 100.1 cc (p&lt; 0.001), compared to the clinical plan, while also reducing the maximum dose. The lung V5 Gy was increased by 5.5% on average (p = 0.02). Doses to the heart, stomach, kidney, large bowel, small bowel and the spinal cord were not compromised. Using avoidance sectors with RapidPlan did not improve plan homogeneity or coverage over the clinical plan, while increasing the V20 Gy to the lungs by 2.8% (p = 0.01). Mean heart dose was increase by 1.1 Gy (p = 0.04), while kidney V18Gy (%) and spinal cord maximum were increased by 7.2% (p = 0.02) and 3.8 Gy respectively (p = 0.01). Volume of the prescription dose outside the PTV was lower by as much as 67 cc while using RapidPlan without avoidance sectors compared to the clinical plan and conformity index (CI) was improved by 7%-8% compared to the clinical plan. Using avoidance sectors worsened the CI by 3%-5% compared with the CP. The RapidPlan model configured for upper, mid and lower thoracic regions without the use of avoidance sectors significantly reduces volumes of the higher doses in the target and therefore potential likelihood of esophageal toxicity without excessively increasing lung dose.</div></div>","PeriodicalId":49837,"journal":{"name":"Medical Dosimetry","volume":"51 1","pages":"Pages 103-116"},"PeriodicalIF":1.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145281544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geometric dose summation in adjuvant EBRT and VCBT for endometrial cancer: A retrospective dosimetric analysis","authors":"İpek Pınar Aral ,&nbsp;Zerrin Gani ,&nbsp;Tarık Kargıoğlu ,&nbsp;Yılmaz Tezcan ,&nbsp;Gonca Altınışık İnan","doi":"10.1016/j.meddos.2025.07.007","DOIUrl":"10.1016/j.meddos.2025.07.007","url":null,"abstract":"<div><div>In patients with gynecologic malignancies treated with external beam radiotherapy (EBRT) and vaginal cuff brachytherapy (VCBT), accurate dose summation is essential for assessing organ-at-risk (OAR) exposure. This study aimed to compare dosimetric differences between rigid image-based plan summation and conventional linear equivalent dose in 2 Gy fractions (EQD2) summation in adjuvant endometrial cancer radiotherapy. Fourteen patients who received adjuvant EBRT and VCBT following hysterectomy were retrospectively analyzed. VCBT plans were converted to EQD2 (α/β = 10) and combined with EBRT plans using rigid image fusion to create a composite “plan sum.” Rectum, bladder, and sigmoid D2cc values were extracted from this summed geometry and compared with D2cc values calculated using the simple-sum method. The “dog-ear” region, representing residual vaginal tissue, was also evaluated. The plan-sum method consistently yielded lower D2cc values for all OARs compared to the simple-sum technique (<em>p</em> = 0.01). Median D2cc values for the rectum, bladder, and sigmoid were 2.12 Gy, 4.06 Gy, and 1.84 Gy lower, respectively. No statistically significant difference was found in mean or minimum dog-ear doses between methods. Rigid image-based plan summation provides more anatomically realistic dose estimates than conventional EQD2 summation. This technique may improve cumulative dose assessment and planning precision in adjuvant VCBT for endometrial cancer, particularly in anatomically stable high-risk regions.</div></div>","PeriodicalId":49837,"journal":{"name":"Medical Dosimetry","volume":"51 1","pages":"Pages 67-71"},"PeriodicalIF":1.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to “Critical appraisal of ‘plan comparison of left-sided breast postmastectomy radiotherapy: Halcyon IMRT and VMAT plan versus TrueBeam IMRT plan’”","authors":"Yibin Zhang B.Med.","doi":"10.1016/j.meddos.2025.10.005","DOIUrl":"10.1016/j.meddos.2025.10.005","url":null,"abstract":"","PeriodicalId":49837,"journal":{"name":"Medical Dosimetry","volume":"51 1","pages":"Pages 154-155"},"PeriodicalIF":1.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145688577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to the letter to the editor regarding “clinical efficacy of AI in lung SABR planning: A comparative retrospective analysis”","authors":"Kylie Unicomb BAppSci (MRS) ,&nbsp;Shamira Cross M.Sc. ,&nbsp;Sean White B.Sc., M.Sc. ,&nbsp;Kevin Vantilburg Dip App Sci ,&nbsp;Gary Low Ph.D. ,&nbsp;Roland Yeghiaian-Alvandi M.B.B.S.","doi":"10.1016/j.meddos.2025.09.003","DOIUrl":"10.1016/j.meddos.2025.09.003","url":null,"abstract":"<div><div>We thank the correspondent for their feedback on our pilot study of AI in lung SABR planning. Our focus was on feasibility and clinical acceptability within routine practice, using a small sample and clinical metrics rather than emphasizing statistical significance. The paired design and blinded review controlled for variability and maintained consistency. We acknowledge limitations and welcome further research on workflow, dosimetry, and AI explainability to advance clinical integration.</div></div>","PeriodicalId":49837,"journal":{"name":"Medical Dosimetry","volume":"51 1","pages":"Pages 9-10"},"PeriodicalIF":1.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145276437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Critical appraisal of “plan comparison of left-sided breast postmastectomy radiotherapy: Halcyon IMRT and VMAT plan versus TrueBeam IMRT plan”","authors":"Parth Aphale Ph.D,&nbsp;Himanshu Shekhar BHMS,&nbsp;Shashank Dokania BHMS","doi":"10.1016/j.meddos.2025.10.006","DOIUrl":"10.1016/j.meddos.2025.10.006","url":null,"abstract":"","PeriodicalId":49837,"journal":{"name":"Medical Dosimetry","volume":"51 1","pages":"Pages 152-153"},"PeriodicalIF":1.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145606769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of dose ratios of hybrid volumetric-modulated arc Therapy plans for nonsmall cell lung cancer","authors":"Kenta Suga MSc ,&nbsp;Keisuke Usui PhD ,&nbsp;Akihiro Arita MSc ,&nbsp;Hiroto Adachi MSc ,&nbsp;Sae Kamiyama MSc ,&nbsp;Hajime Sakamoto PhD ,&nbsp;Shinsuke Kyogoku MD, PhD ,&nbsp;Hiroyuki Daida MD, PhD","doi":"10.1016/j.meddos.2025.08.001","DOIUrl":"10.1016/j.meddos.2025.08.001","url":null,"abstract":"<div><div>This study investigated hybrid volumetric-modulated arc therapy (H-VMAT) for the treatment of nonsmall cell lung cancer (NSCLC) by classifying patients based on the tumor location (left or right and upper, middle or low) and planning target volume (PTV) (less than average or greater than average) to determine the optimal VMAT dose ratio by dividing the prescription dose used for H-VMAT planning. The following treatment plans comprising four-field conformal irradiation were created for 51 patients with NSCLC: VMAT with one full arc (f-VMAT); VMAT with two partial arcs (p-VMAT); and hybrid plans. Hybrid plans comprised a combination of f-VMAT and three-dimensional conformal radiation therapy (3D-CRT; fH-VAMT) as well as a combination of p-VMAT and 3D-CRT (pH-VMAT). We evaluated the dose to the organ at risk using lung V5 and V20 Gy, heart V30 and V40 Gy, and the mean heart dose and determined the optimal dose ratio of H-VMAT. H-VMAT resulted in negligible differences in the PTV conformity and homogeneity of fH-VMAT and pH-VMAT regardless of the dose ratio. Compared to fH-VMAT, pH-VMAT significantly reduced low lung doses, particularly those for tumors located in the right and above the heart, and those for larger target volumes. Compared to fH-VMAT, pH-VMAT slightly reduced the heart volume exposed to medium or high doses. The optimal VMAT dose ratios based on the tumor conditions were as follows: 30 % fH-VMAT and 50 % pH-VMAT for left lung tumors; 20 % fH-VMAT and 50 % pH-VMAT for right lung tumors; 20 % fH-VMAT and 50 % pH-VMAT for tumors above the heart; and 50 % fH-VMAT and 50 % pH-VMAT for tumors at the heart level. For smaller tumors, both fH-VMAT and pH-VMAT were set at 50 %. For larger tumors, 20 % fH-VMAT and 50 % pH-VMAT were used. These findings can help optimize treatment planning and guidelines and contribute to improved patient outcomes.</div></div>","PeriodicalId":49837,"journal":{"name":"Medical Dosimetry","volume":"51 1","pages":"Pages 72-83"},"PeriodicalIF":1.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Directed Journal Reading (DJR) Program, Spring 2026","authors":"","doi":"10.1016/j.meddos.2026.01.002","DOIUrl":"10.1016/j.meddos.2026.01.002","url":null,"abstract":"","PeriodicalId":49837,"journal":{"name":"Medical Dosimetry","volume":"51 1","pages":"Page 156"},"PeriodicalIF":1.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146049165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of a robust and homogeneous volumetric modulated arc therapy based total body irradiation technique and analysis of dose rate using Elekta solutions","authors":"Surendran Jagadeesan ,&nbsp;Karthikeyan Kalyanasundaram ,&nbsp;Majed Alghamdi ,&nbsp;Moaz Mohammed ,&nbsp;Raad Sweidan ,&nbsp;Alaa Abdalqader ,&nbsp;Yoginee Sonawane ,&nbsp;Humaid Al-Shamsi ,&nbsp;Ibrahim Abu-Gheida","doi":"10.1016/j.meddos.2025.06.003","DOIUrl":"10.1016/j.meddos.2025.06.003","url":null,"abstract":"<div><div>Volumetric Modulated Arc Therapy (VMAT) for Total Body Irradiation (TBI) provides superior coverage, homogeneity, and organ sparing, leading to reduced toxicity. In this study, we present a VMAT-TBI technique delivered using Elekta solutions and report the average beam and lung dose rates. Nine patients were treated by VMAT-TBI technique. Treatment planning included VMAT for the upper body and VMAT or inverse optimized dynamic multileaf collimator (dMLC) plan using anteroposterior-posteroanterior (AP/PA) fields for the lower body. Plan robustness was evaluated for the 9 patients. Treatment log data was recorded with a sampling rate of 250 ms in the linear accelerator (linac) computer used for assessing the beam dose rates and delivery time. The average volume of all PTV receiving 95% of the prescription dose was 95.7 ± 1.3%. The mean heterogeneity index was 0.16 ± 0.03. The lung, kidney, and heart mean doses were 7.8 ± 0.2 Gy, 6.8 ± 0.3 Gy, and 6.8 ± 0.2 Gy, respectively, and the oral avoidance mean dose was 4.8 ± 0.6 Gy for myeloablative regimens. Robustness evaluation revealed the deviation of lung mean dose and the PTV maximum dose within 5% and 12.5%, respectively, with a 5 mm longitudinal isocenter shift. The mean instantaneous dose rate (IDR) for the thorax VMAT beam was 217 ± 26 MU/min. The average lung volume receiving above 20 cGy/min was 24.7 ± 8.2%. VMAT-TBI provides a homogeneous, robust, and selective organ-sparing treatment. Lung average dose rates can be reduced without any control applied to the IDR.</div></div>","PeriodicalId":49837,"journal":{"name":"Medical Dosimetry","volume":"51 1","pages":"Pages 23-31"},"PeriodicalIF":1.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144745829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}