Neurology Psychiatry and Brain Research最新文献

{"title":"Depression and its association with quality of life among elderly: An elderly home- cross sectional study","authors":"Kenison Shrestha ,&nbsp;Saroj Prasad Ojha ,&nbsp;Saraswati Dhungana ,&nbsp;Sneha Shrestha","doi":"10.1016/j.npbr.2020.08.003","DOIUrl":"10.1016/j.npbr.2020.08.003","url":null,"abstract":"<div><h3>Background</h3><p>Elderly population is on the rise and elderly depression is very common. Institutionalization further increases the risk of them being more depressed and can have impact on quality of life. The aim of this study was to find the prevalence of depression in institutionalized elders and assess for the demographic correlates and also assess the quality of life.</p></div><div><h3>Method</h3><p>An institutionalized based cross- sectional study was conducted from September 2017−18. A total of 159 elders residing in old age home were included in the study. The validated Nepali translation of Geriatric Depression Scale -15 item was used to assess the depression and quality of life was measured using world health organization quality of life- brief. The collected data were coded and analyzed using SPSS version 16. The descriptive statistics was calculated for socio- demographic and association with depression was analyzed using chi square test. The correlation between depression status and quality of life was done using non- parametric Spearman’s rank correlation coefficient test.</p></div><div><h3>Results</h3><p>Among the 159 elderly subjects interviewed, prevalence of depression was 39.6 % with mean age of 76 years. Depression in institutionalized elders was found to be more in males (42 %). There was significant association between age, gender and depression status (p &lt; 0.05) whereas there was negative correlation in between depression status and quality of life.</p></div><div><h3>Conclusion</h3><p>The finding of this study concluded that depression among institutionalized elders was a substantial problem and affected their quality of life.</p></div>","PeriodicalId":49756,"journal":{"name":"Neurology Psychiatry and Brain Research","volume":"38 ","pages":"Pages 1-4"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.npbr.2020.08.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41442096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can daily internet use time screen for problematic internet use among college students? A receiver operator characteristic curve-based multi-country study","authors":"Yatan Pal Singh Balhara ,&nbsp;Swarndeep Singh ,&nbsp;Ana Doric ,&nbsp;Dejan Stevanovic ,&nbsp;Rajna Knez ,&nbsp;Mita Rani Roy Chowdhury ,&nbsp;Helin Yilmaz Kafali ,&nbsp;Pawan Sharma ,&nbsp;Zahir Vally ,&nbsp;Tuong Vi Vu ,&nbsp;Sidharth Arya ,&nbsp;Aishita Mahendru ,&nbsp;Ramdas Ransing ,&nbsp;Gamze Erzin ,&nbsp;Huynh Le Thi Cam Hong Le","doi":"10.1016/j.npbr.2020.09.002","DOIUrl":"10.1016/j.npbr.2020.09.002","url":null,"abstract":"<div><h3>Background and objective</h3><p>The current article explored the possibility of using daily internet use time as an indicator for problematic internet use (PIU) among college/ university students based on observations from a multi-centric, multi-country study conducted across eight different countries. Additionally, the current article explored whether daily night time sleep and physical activity can serve as possible indicators of PIU.</p></div><div><h3>Methods</h3><p>The present article presents the findings from analysis of information collected from 2643 college/university students from eight countries. Area under the ROC curve (AUC) was calculated to compare the predictive performance of three different indicator variables in the study participants to determine PIU.</p></div><div><h3>Results</h3><p>The AUC for daily internet use time was 0.64 (95 % CI: 0.62 to 0.656), which was higher than the AUC for weekly physical activity (0.599; 95 % CI: 0.580 to 0.618) and daily night time sleep (0.563; 95 % CI: 0.544 to 0.582). The AUC for three indicator variables was compared, which showed that the AUC for daily internet time was significantly higher than the AUC for daily night-time sleep.</p></div><div><h3>Conclusions</h3><p>The assessment of daily internet use time as part of a larger battery of general health-related questions could be applied periodically among young students for screening of PIU in addition to a host of other important mental and physical health related conditions and behaviors. However, further studies are needed to determine optimal cut-off depending upon the desired trade-off between sensitivity and specificity for screening among different populations.</p></div>","PeriodicalId":49756,"journal":{"name":"Neurology Psychiatry and Brain Research","volume":"38 ","pages":"Pages 43-48"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.npbr.2020.09.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46492429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lilo Süllwold (1930–2020): Her contributions to psychopathology and psychological treatment of schizophrenia according the basic symptoms concept","authors":"Natalia Jimeno","doi":"10.1016/j.npbr.2020.10.008","DOIUrl":"10.1016/j.npbr.2020.10.008","url":null,"abstract":"","PeriodicalId":49756,"journal":{"name":"Neurology Psychiatry and Brain Research","volume":"38 ","pages":"Pages 121-123"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.npbr.2020.10.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44455791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cortico-hippocampal morphology and behavioural indices improved in maternal deprivation model of schizophrenia following vitamin B complex supplementation","authors":"Gabriel Olaiya Omotoso,&nbsp;Fatimah Adeola Abdulsalam,&nbsp;Nafisat Yetunde Mutholib,&nbsp;Abdulkabir I. Bature,&nbsp;Ismail Temitayo Gbadamosi","doi":"10.1016/j.npbr.2020.10.007","DOIUrl":"https://doi.org/10.1016/j.npbr.2020.10.007","url":null,"abstract":"<div><h3>Background</h3><p>Maternal deprivation (MD) during early life development has been documented to culminate in long-term alterations in brain function and behavioural manifestations that mimic schizophrenia. This study elucidated the putative neuroprotective roles of vitamin B complex in MD-induced behavioural and neurochemical modifications in hippocampus and prefrontal cortex (PFC) of Wistar rats.</p></div><div><h3>Materials and methods</h3><p>: Rat pups were maternally deprived on postnatal day 9 for 24 h and then treated with or without vitamin B complex for 15 days while a control group was undisturbed during the experimental period. The rats were then subjected to behavioural paradigms to measure memory indices and anxiety levels. The rats were sacrificed to obtain the PFC and hippocampus for histomorphological and biochemical analysis.</p></div><div><h3>Results</h3><p>Behavioural analysis of the animals revealed that MD induced a declination in long- and short-term memory in addition to anxiety-like behaviour in the open field test. Cortico-hippocampal histomorphology of these animals showed an increased astrocytic density and chromatolysis, which were accompanied by reduced levels of superoxide dismutase and catalase enzymes. Vitamin B complex mitigated MD-induced behavioural decline, histomorphological perturbation and oxidative stress by enhancing the intrinsic antioxidant defence, thereby culminating in nootropic behaviour and reduced anxiety.</p></div><div><h3>Conclusion</h3><p>We confirmed the hypothesis that vitamin B complex is neuroprotective against neuropathological alterations induced by maternal deprivation.</p></div>","PeriodicalId":49756,"journal":{"name":"Neurology Psychiatry and Brain Research","volume":"38 ","pages":"Pages 74-82"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.npbr.2020.10.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91649868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute changes in cerebral blood flow after single-infusion ketamine in major depression: A pilot study","authors":"Sara Gonzalez ,&nbsp;Megha M. Vasavada ,&nbsp;Stephanie Njau ,&nbsp;Ashish K. Sahib ,&nbsp;Randall Espinoza ,&nbsp;Katherine L. Narr ,&nbsp;Amber M. Leaver","doi":"10.1016/j.npbr.2020.08.006","DOIUrl":"10.1016/j.npbr.2020.08.006","url":null,"abstract":"<div><h3>Background</h3><p>Ketamine provides rapid antidepressant response in those struggling with major depressive disorder (MDD). This study measured acute changes in brain activity over 24 h after a single infusion of ketamine using arterial spin labeled (ASL) functional magnetic resonance imaging (fMRI) in patients with MDD. ASL is a novel technique that provides quantitative values to measure cerebral blood flow (CBF).</p></div><div><h3>Methods</h3><p>A single sub-anesthetic dose (0.5 mg/kg) of ketamine was delivered intravenously. Treatment-refractory patients (n = 11) were assessed at: Baseline (pre-infusion), and approximately 1 h, 6 h, and 24 h post-infusion. Linear mixed-effects models detected changes in CBF with respect to treatment outcome, and results were corrected for false discovery rate (FDR).</p></div><div><h3>Results</h3><p>After ketamine infusion, increased CBF was observed in the thalamus, while decreased CBF was observed in lateral occipital cortex in all patients. Time-by-response interactions were noted in ventral basal ganglia and medial prefrontal cortex, where CBF change differed according to antidepressant response.</p></div><div><h3>Limitations</h3><p>Modest sample size is a limitation of this pilot study; strict statistical correction and visualization of single-subject data attempted to ameliorate this issue.</p></div><div><h3>Conclusion</h3><p>In this pilot study, a sub-anesthetic dose of ketamine was associated with acute neurofunctional changes that may be consistent with altered attention, specifically increased thalamus activity coupled with decreased cortical activity. By contrast, antidepressant response to ketamine was associated with changes in reward-system regions, specifically ventral basal ganglia and medial prefrontal cortex. Further work is needed to determine whether these results generalize to larger samples and/or serial ketamine infusions associated with longer-lasting clinical effects.</p></div>","PeriodicalId":49756,"journal":{"name":"Neurology Psychiatry and Brain Research","volume":"38 ","pages":"Pages 5-11"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.npbr.2020.08.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39709319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental health research in the lower-middle-income countries of Africa and Asia during the COVID-19 pandemic: A scoping review","authors":"Sujita Kumar Kar ,&nbsp;Tosin Philip Oyetunji ,&nbsp;Aathira J. Prakash ,&nbsp;Olusegun Ayomikun Ogunmola ,&nbsp;Sarvodaya Tripathy ,&nbsp;Monsurat M. Lawal ,&nbsp;Zainab K. Sanusi ,&nbsp;S.M. Yasir Arafat","doi":"10.1016/j.npbr.2020.10.003","DOIUrl":"10.1016/j.npbr.2020.10.003","url":null,"abstract":"<div><h3>Background</h3><p>Lower middle - income countries of Africa and Asia have accommodated a large portion of the world’s population, where mental health research has been under-prioritized. This study aimed to review all published research on mental health issues related to the COVID-19 pandemic in lower middle - income countries of the Afro-Asian region.</p></div><div><h3>Methods</h3><p>A search was conducted in the PubMed and PubMed Central databases using the terms \"mental health,\" \"psychiatric disorders,\" \"COVID-19\", \"coronavirus,\" \"Asia,\" \"Africa,\" \"Lower Middle-income countries.\" All articles published in the English language until 3^rd July 2020 were included.</p></div><div><h3>Result</h3><p>A total of 133 papers were found in lower-middle-income countries of Africa (n = 11) and Asia (n = 122), which discussed various aspects of mental health in the context of COVID-19. Most of the studies are cross-sectional studies that addressed mental morbidities, psychological reactions, stress, coping among the general population, and focused groups (healthcare workers, students, elderly, patients). Researchers attempted to develop and validate tools that measure certain psychological constructs (fear, anxiety) concerning COVID-19. Online surveys were the primary modality of researching this COVID-19 pandemic.</p></div><div><h3>Conclusion</h3><p>COVID-19 related mental health research is scarce in lower-middle-income countries of Africa and Asia. Available researches suggest that mental health challenges during this COVID-19 pandemic are enormous and need attention. There is a need for policy and recommendations to deal with the mental health challenges in lower middle - income countries of Africa and Asia.</p></div>","PeriodicalId":49756,"journal":{"name":"Neurology Psychiatry and Brain Research","volume":"38 ","pages":"Pages 54-64"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.npbr.2020.10.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38578238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of Thai media reporting of suicidal behavior: Compliance against the World Health Organization media guidelines","authors":"Marthoenis Marthoenis ,&nbsp;Hasina Akter ,&nbsp;S.M. Yasir Arafat","doi":"10.1016/j.npbr.2020.09.003","DOIUrl":"10.1016/j.npbr.2020.09.003","url":null,"abstract":"<div><h3>Background</h3><p>Although media reporting has influence on suicide there has no report in Thailand regarding the quality of media in reporting suicidal news.</p></div><div><h3>Objectives</h3><p>This study aimed to assess the quality of English language media reports of suicidal behaviors in Thailand against the World Health Organization (WHO) media guidelines.</p></div><div><h3>Methods</h3><p>We scrutinized the suicide news contents of four purposively selected English language newspapers in Thailand. Using Google search function of the online newspapers, the keywords of “suicide”, “hanging self”, and “drink poison” were used to search the suicide-related news contents.</p></div><div><h3>Results</h3><p>The vast majority of English newspapers in Thailand reported harmful information in reporting suicide-related news. Almost all reported locations where the suicide took place, methods of suicide, gender and age of the victim. Approximately one-fourth also showed a picture of the person who died by suicide.</p></div><div><h3>Conclusions</h3><p>The English online newspaper in Thailand did not follow the WHO media guidelines in reporting suicide news. Harmful information to the readers was presented in both title and content of the news. Meanwhile, potentially helpful information such as who to contact or where to seek help had been rarely reported.</p></div>","PeriodicalId":49756,"journal":{"name":"Neurology Psychiatry and Brain Research","volume":"38 ","pages":"Pages 39-42"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.npbr.2020.09.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42291359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emotion regulation strategies and psychological wellbeing: Examining cognitive reappraisal and expressive suppression in an Emirati college sample","authors":"Zahir Vally ,&nbsp;Khalid Ahmed","doi":"10.1016/j.npbr.2020.09.001","DOIUrl":"10.1016/j.npbr.2020.09.001","url":null,"abstract":"<div><h3>Background</h3><p>Cognitive reappraisal (CR) and expressive suppression (ES) are emotion regulation strategies that have been demonstrated to be differentially associated with psychological wellbeing. However, this relationship has never been investigated in a Middle Eastern sample.</p></div><div><h3>Method</h3><p>As a contribution to the literature, we employed a cross-sectional design in which 147 college students in the United Arab Emirates were sampled (<em>m</em>_age = 21.37 years, <em>SD</em> = 4.76). We examined the extent to which CR and ES are used in this context and investigated the association between the use of these two emotion regulation strategies and affect (both positive and negative), flourishing, academic achievement, and social support.</p></div><div><h3>Results</h3><p><span>A series of hierarchical linear regressions indicated that the use of CR was positively associated with positive affect (</span><em>β</em> = 0.35), flourishing (<em>β</em> = 0.52), emotional coping (<em>β</em> = 0.15), and instrumental coping (<em>β</em> = 0.19), and negatively with negative affect (<em>β</em> = −0.20). ES was positively associated with negative affect (<em>β</em> = 0.20), and negatively with both emotional (<em>β</em> = −0.40) and instrumental coping (<em>β</em> = −0.24). Academic achievement was not significantly associated with either CR or ES.</p></div><div><h3>Conclusions</h3><p>This study finds that the use of emotion regulation strategies parallel those obtained elsewhere in the world. Despite cultural variations, participants in this sample also evidenced a preference for the use of CR during times of distress and its use is associated with elevated psychological wellbeing.</p></div>","PeriodicalId":49756,"journal":{"name":"Neurology Psychiatry and Brain Research","volume":"38 ","pages":"Pages 27-32"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.npbr.2020.09.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42965287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive impairment and its associated factors among HIV/AIDS patients on anti retro -viral therapy in Sub-Saharan Africa: Systematic review and meta-analysis","authors":"Getachew Yideg Yitbarek ,&nbsp;Gashaw Walle Ayehu ,&nbsp;Belete Achamyelew Ayele ,&nbsp;Wubet Alebachew Bayih ,&nbsp;Alemayehu Digssie Gebremariam ,&nbsp;Sofonyas Abebaw Tiruneh","doi":"10.1016/j.npbr.2020.11.002","DOIUrl":"10.1016/j.npbr.2020.11.002","url":null,"abstract":"<div><h3>Background</h3><p>The nature of HIV-related Neurocognitive disorders has rapidly evolved with the widespread use of anti-retro viral treatment. The aim of this study was to estimate the pooled prevalence of cognitive impairment and its associated factors in Sub -Saharan Africa using previous studies.</p></div><div><h3>Methods</h3><p>Databases, PubMed, Hinari, Google Scholar was used to search for potential studies. Data were extracted using MS excel and exported to STATA/MP version 16.0 for further analysis. Heterogeneity between studies was tested using Cochrane Q test statistics and I² test and small study effect were checked using Egger’s statistical test at 5 % significant level. Sensitivity analysis was checked. A random-effects model was employed to estimate the pooled prevalence of cognitive impairment and its associated factors in Sub Saharan Africa.</p></div><div><h3>Result</h3><p>Twenty one studies included to estimate the pooled prevalence of cognitive impairment in sub Saharan Africa. In random effects model, the pooled prevalence of cognitive impairment in sub Saharan Africa was 44.46 (95 % CI, 34.22, and 54.69). Level of education had significant association with cognitive impairment and those participants with below secondary education level are two times more likely to develop cognitive impairment compared to those who are diploma and above (POR = 2.33, 95 % CI, 1.42, 3.82). From random effects model estimates, the pooled odds of developing cognitive impairment among female were nearly 3 times than male (POR = 2.87, 95 % CI, 2.09, 3.95).</p></div><div><h3>Conclusion</h3><p>The pooled prevalence of cognitive impairment in Sub-Saharan Africa was significantly high. Sex and educational level of the participants were statistically significant factors for cognitive impairment. Based on the finding of this review, we recommend that continuous screening of cognitive impairment, identification of the possible risk factors, and proper management strategy should be designed in each Anti retro-viral therapy (ART) centers of Sub Saharan African countries.</p></div>","PeriodicalId":49756,"journal":{"name":"Neurology Psychiatry and Brain Research","volume":"38 ","pages":"Pages 83-91"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.npbr.2020.11.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44624634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social cognition correlation to white matter integrity alteration in mirror neurons of schizophrenic patients: DTI study","authors":"Heba Hamed ElShahawi ,&nbsp;Hossam Moussa Sakr ,&nbsp;Mostafa Ahmad Hashim ,&nbsp;Hadeer Hassan Mohamed ,&nbsp;Mai SeifElDin Abdeen","doi":"10.1016/j.npbr.2020.10.004","DOIUrl":"10.1016/j.npbr.2020.10.004","url":null,"abstract":"<div><h3>Background</h3><p>It is postulated that mirror neurons (MNs) abnormalities are associated with social skills.</p></div><div><h3>Objectives</h3><p>Using DTI, altered structural connectivity and its association with social cognition in MNs-hub regions was investigated in schizophrenia in comparison to healthy.</p></div><div><h3>Methods</h3><p>Fifteen patients with schizophrenia in their first episode and 15 healthy controls were included in this study. They were subjected to the Structured Clinical Interview for DSM-IV Axis I Disorder (SCID-I), Scale for the Assessment of Negative Symptoms (SANS), with special consideration to “Anhedonia and Asociality” subscale, Scale for the Assessment of Positive Symptoms (SAPS) and a comprehensive cognitive assessment. DTI scans were acquired in patients and controls. FA and Trace of the regions of interest rich in mirror neurons were evaluated, i.e., anterior cingulate cortex (ACC), inferior parietal lobe (IPL) and premotor cortex (PMC).</p></div><div><h3>Results</h3><p>A significant difference in Trace of these 3 regions was observed in schizophrenia patients. There were no group differences in FA. There was a significant positive correlation between the Trace of the right IPL and right and left PMA, with the “Anhedonia &amp; Associability” subscale.</p></div><div><h3>Conclusions</h3><p>Mirror neuron system in schizophrenia patients might be connected to negative symptoms, more specifically, to social deficits.</p></div>","PeriodicalId":49756,"journal":{"name":"Neurology Psychiatry and Brain Research","volume":"38 ","pages":"Pages 65-73"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.npbr.2020.10.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48844694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}