Thomas Woodcock, Elisa G Liberati, Mary Dixon-Woods
{"title":"A mixed-methods study of challenges experienced by clinical teams in measuring improvement.","authors":"Thomas Woodcock, Elisa G Liberati, Mary Dixon-Woods","doi":"10.1136/bmjqs-2018-009048","DOIUrl":"10.1136/bmjqs-2018-009048","url":null,"abstract":"<p><strong>Objective: </strong>Measurement is an indispensable element of most quality improvement (QI) projects, but it is undertaken to variable standards. We aimed to characterise challenges faced by clinical teams in undertaking measurement in the context of a safety QI programme that encouraged local selection of measures.</p><p><strong>Methods: </strong>Drawing on an independent evaluation of a multisite improvement programme (Safer Clinical Systems), we combined a qualitative study of participating teams' experiences and perceptions of measurement with expert review of measurement plans and analysis of data collected for the programme. Multidisciplinary teams of frontline clinicians at nine UK NHS sites took part across the two phases of the programme between 2011 and 2016.</p><p><strong>Results: </strong>Developing and implementing a measurement plan against which to assess their improvement goals was an arduous task for participating sites. The operational definitions of the measures that they selected were often imprecise or missed important details. Some measures used by the teams were not logically linked to the improvement actions they implemented. Regardless of the specific type of data used (routinely collected or selected ex novo), the burdensome nature of data collection was underestimated. Problems also emerged in identifying and using suitable analytical approaches.</p><p><strong>Conclusion: </strong>Measurement is a highly technical task requiring a degree of expertise. Simply leveraging individual clinicians' motivation is unlikely to defeat the persistent difficulties experienced by clinical teams when attempting to measure their improvement efforts. We suggest that more structural initiatives and broader capability-building programmes should be pursued by the professional community. Improving access to, and ability to use repositories of validated measures, and increasing transparency in reporting measurement attempts, is likely to be helpful.</p>","PeriodicalId":49653,"journal":{"name":"Quality & Safety in Health Care","volume":"30 1","pages":"106-115"},"PeriodicalIF":0.0,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841469/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47607290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Working conditions and their impact on work satisfaction in migrating and non-migrating workers. Factor structure of the Polish version of the Working Conditions Questionnaire.","authors":"Radosław B Walczak, Macarena Vallejo-Martín","doi":"10.5114/hpr.2020.99208","DOIUrl":"10.5114/hpr.2020.99208","url":null,"abstract":"<p><strong>Background: </strong>The study compares the impact of working conditions and wages as predictors of work satisfaction of Poles, working in Poland and abroad. Although the work environment plays a crucial role in determining the work satisfaction of migrants, most mention higher income abroad as the main migration motive. The increased income may not boost the work satisfaction however, because during migration the wage reference point changes. Based on those observations, it was assumed that working conditions will have a greater impact on migrants' work satisfaction than nominal earnings. Additionally, migrants, while having higher nominal wages, should subjectively judge them as lower.</p><p><strong>Participants and procedure: </strong>Two samples - 351 subjects working in Poland, and 158 working in the UK and Germany - were analyzed. Everyone filled in an online survey including questions about their work environment and income, the Polish versions of the Working Conditions Questionnaire and the Work Satisfaction Scale. The results of the structural analyses (EFA and CFA) and between-sample measurement invariance of the Working Conditions Questionnaire were obtained. Migrants and stayers were compared using a Kruskal-Wallis ANOVA. The impact of working conditions and wages on work satisfaction was analyzed with multiple linear regression.</p><p><strong>Results: </strong>The factorial structure of the Working Conditions Questionnaire in the Polish version is comparable to the Spanish original. Additionally, the nominal wages were perceived as higher for migrants than stayers. The reverse was true for subjective wage evaluations. Some working conditions were shown to have a significant impact on work satisfaction.</p><p><strong>Conclusions: </strong>The Polish version of the Working Conditions Questionnaire is an internally consistent and reliable tool for measuring work properties. Higher nominal wages of migrants do not lead to their higher work satisfaction. Working conditions are a better predictor of work satisfaction than wages for all analyzed groups.</p>","PeriodicalId":49653,"journal":{"name":"Quality & Safety in Health Care","volume":"22 1","pages":"87-100"},"PeriodicalIF":2.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10694610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85937351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jennifer S Myers, Meghan Brooks Lane-Fall, Angela Ross Perfetti, Kate Humphrey, Luke Sato, Kathy N Shaw, April M Taylor, Anjala Tess
{"title":"Demonstrating the value of postgraduate fellowships for physicians in quality improvement and patient safety.","authors":"Jennifer S Myers, Meghan Brooks Lane-Fall, Angela Ross Perfetti, Kate Humphrey, Luke Sato, Kathy N Shaw, April M Taylor, Anjala Tess","doi":"10.1136/bmjqs-2019-010204","DOIUrl":"10.1136/bmjqs-2019-010204","url":null,"abstract":"<p><strong>Background: </strong>Academic fellowships in quality improvement (QI) and patient safety (PS) have emerged as one strategy to fill a need for physicians who possess this expertise. The authors aimed to characterise the impact of two such programmes on the graduates and their value to the institutions in which they are housed.</p><p><strong>Methods: </strong>In 2018, a qualitative study of two US QIPS postgraduate fellowship programmes was conducted. Graduates' demographics and titles were collected from programme files,while perspectives of the graduates and their institutional mentors were collected through individual interviews and analysed using thematic analysis.</p><p><strong>Results: </strong>Twenty-eight out of 31 graduates (90%) and 16 out of 17 (94%) mentors participated in the study across both institutions. At a median of 3 years (IQR 2-4) postgraduation, QIPS fellowship programme graduates' effort distribution was: 50% clinical care (IQR 30-61.8), 48% QIPS administration (IQR 20-60), 28% QIPS research (IQR 17.5-50) and 15% education (7.1-30.4). 68% of graduates were hired in the health system where they trained. Graduates described learning the requisite hard and soft skills to succeed in QIPS roles. Mentors described the impact of the programme on patient outcomes and increasing the acceptability of the field within academic medicine culture.</p><p><strong>Conclusion: </strong>Graduates from two QIPS fellowship programmes and their mentors perceive programmatic benefits related to individual career goal attainment and institutional impact. The results and conceptual framework presented here may be useful to other academic medical centres seeking to develop fellowships for advanced physician training programmes in QIPS.</p>","PeriodicalId":49653,"journal":{"name":"Quality & Safety in Health Care","volume":"29 1","pages":"645-654"},"PeriodicalIF":0.0,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmjqs-2019-010204","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48531362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Simon Bailey, Carianne Hunt, Adam Brisley, Susan Howard, Lynne Sykes, Thomas Blakeman
{"title":"Implementation of clinical decision support to manage acute kidney injury in secondary care: an ethnographic study.","authors":"Simon Bailey, Carianne Hunt, Adam Brisley, Susan Howard, Lynne Sykes, Thomas Blakeman","doi":"10.1136/bmjqs-2019-009932","DOIUrl":"10.1136/bmjqs-2019-009932","url":null,"abstract":"<p><strong>Background: </strong>Over the past decade, acute kidney injury (AKI) has become a global priority for improving patient safety and health outcomes. In the UK, a confidential inquiry into AKI led to the publication of clinical guidance and a range of policy initiatives. National patient safety directives have focused on the mandatory establishment of clinical decision support systems (CDSSs) within all acute National Health Service (NHS) trusts to improve the detection, alerting and response to AKI. We studied the organisational work of implementing AKI CDSSs within routine hospital care.</p><p><strong>Methods: </strong>An ethnographic study comprising non-participant observation and interviews was conducted in two NHS hospitals, delivering AKI quality improvement programmes, located in one region of England. Three researchers conducted a total of 49 interviews and 150 hours of observation over an 18-month period. Analysis was conducted collaboratively and iteratively around emergent themes, relating to the organisational work of technology adoption.</p><p><strong>Results: </strong>The two hospitals developed and implemented AKI CDSSs using very different approaches. Nevertheless, both resulted in adaptive work and trade-offs relating to the technology, the users, the organisation and the wider system of care. A common tension was associated with attempts to maximise benefit while minimise additional burden. In both hospitals, resource pressures exacerbated the tensions of translating AKI recommendations into routine practice.</p><p><strong>Conclusions: </strong>Our analysis highlights a conflicted relationship between external context (policy and resources), and organisational structure and culture (eg, digital capability, attitudes to quality improvement). Greater consideration is required to the long-term effectiveness of the approaches taken, particularly in light of the ongoing need for adaptation to incorporate new practices into routine work.</p>","PeriodicalId":49653,"journal":{"name":"Quality & Safety in Health Care","volume":"29 1","pages":"382-389"},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47231062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pascale Carayon, Peter Hoonakker, Ann Schoofs Hundt, Megan Salwei, Douglas Wiegmann, Roger L Brown, Peter Kleinschmidt, Clair Novak, Michael Pulia, Yudi Wang, Emily Wirkus, Brian Patterson
{"title":"Application of human factors to improve usability of clinical decision support for diagnostic decision-making: a scenario-based simulation study.","authors":"Pascale Carayon, Peter Hoonakker, Ann Schoofs Hundt, Megan Salwei, Douglas Wiegmann, Roger L Brown, Peter Kleinschmidt, Clair Novak, Michael Pulia, Yudi Wang, Emily Wirkus, Brian Patterson","doi":"10.1136/bmjqs-2019-009857","DOIUrl":"10.1136/bmjqs-2019-009857","url":null,"abstract":"<p><strong>Objective: </strong>In this study, we used human factors (HF) methods and principles to design a clinical decision support (CDS) that provides cognitive support to the pulmonary embolism (PE) diagnostic decision-making process in the emergency department. We hypothesised that the application of HF methods and principles will produce a more usable CDS that improves PE diagnostic decision-making, in particular decision about appropriate clinical pathway.</p><p><strong>Materials and methods: </strong>We conducted a scenario-based simulation study to compare a HF-based CDS (the so-called CDS for PE diagnosis (PE-Dx CDS)) with a web-based CDS (MDCalc); 32 emergency physicians performed various tasks using both CDS. PE-Dx integrated HF design principles such as automating information acquisition and analysis, and minimising workload. We assessed all three dimensions of usability using both objective and subjective measures: effectiveness (eg, appropriate decision regarding the PE diagnostic pathway), efficiency (eg, time spent, perceived workload) and satisfaction (perceived usability of CDS).</p><p><strong>Results: </strong>Emergency physicians made more appropriate diagnostic decisions (94% with PE-Dx; 84% with web-based CDS; p<0.01) and performed experimental tasks faster with the PE-Dx CDS (on average 96 s per scenario with PE-Dx; 117 s with web-based CDS; p<0.001). They also reported lower workload (p<0.001) and higher satisfaction (p<0.001) with PE-Dx.</p><p><strong>Conclusions: </strong>This simulation study shows that HF methods and principles can improve usability of CDS and diagnostic decision-making. Aspects of the HF-based CDS that provided cognitive support to emergency physicians and improved diagnostic performance included automation of information acquisition (eg, auto-populating risk scoring algorithms), minimisation of workload and support of decision selection (eg, recommending a clinical pathway). These HF design principles can be applied to the design of other CDS technologies to improve diagnostic safety.</p>","PeriodicalId":49653,"journal":{"name":"Quality & Safety in Health Care","volume":"29 1","pages":"329-340"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmjqs-2019-009857","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42850012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rachel Ann Elliott, Matthew J Boyd, Lukasz Tanajewski, Nick Barber, Georgios Gkountouras, Anthony J Avery, Rajnikant Mehta, James E Davies, Nde-Eshimuni Salema, Christopher Craig, Asam Latif, Justin Waring, Antony Chuter
{"title":"'New Medicine Service': supporting adherence in people starting a new medication for a long-term condition: 26-week follow-up of a pragmatic randomised controlled trial.","authors":"Rachel Ann Elliott, Matthew J Boyd, Lukasz Tanajewski, Nick Barber, Georgios Gkountouras, Anthony J Avery, Rajnikant Mehta, James E Davies, Nde-Eshimuni Salema, Christopher Craig, Asam Latif, Justin Waring, Antony Chuter","doi":"10.1136/bmjqs-2018-009177","DOIUrl":"10.1136/bmjqs-2018-009177","url":null,"abstract":"<p><strong>Objective: </strong>To examine the effectiveness and cost-effectiveness of the community pharmacy New Medicine Service (NMS) at 26 weeks.</p><p><strong>Methods: </strong>Pragmatic patient-level parallel randomised controlled trial in 46 English community pharmacies. 504 participants aged ≥14, identified in the pharmacy when presenting a prescription for a new medicine for predefined long-term conditions, randomised to receive NMS (n=251) or normal practice (n=253) (NMS intervention: 2 consultations 1 and 2 weeks after prescription presentation). Adherence assessed through patient self-report at 26-week follow-up. Intention-to-treat analysis employed. National Health Service (NHS) costs calculated. Disease-specific Markov models estimating impact of non-adherence combined with clinical trial data to calculate costs per extra quality-adjusted life-year (QALY; NHS England perspective).</p><p><strong>Results: </strong>Unadjusted analysis: of 327 patients still taking the initial medicine, 97/170 (57.1%) and 103/157 (65.6%) (p=0.113) patients were adherent in normal practice and NMS arms, respectively. Adjusted intention-to-treat analysis: adherence OR 1.50 (95% CI 0.93 to 2.44, p=0.095), in favour of NMS. There was a non-significant reduction in 26-week NHS costs for NMS: -£104 (95% CI -£37 to £257, p=0.168) per patient. NMS generated a mean of 0.04 (95% CI -0.01 to 0.13) more QALYs per patient, with mean reduction in lifetime cost of -£113.9 (-1159.4, 683.7). The incremental cost-effectiveness ratio was -£2758/QALY (2.5% and 97.5%: -38 739.5, 34 024.2. NMS has an 89% probability of cost-effectiveness at a willingness to pay of £20 000 per QALY.</p><p><strong>Conclusions: </strong>At 26-week follow-up, NMS was unable to demonstrate a statistically significant increase in adherence or reduction in NHS costs, which may be attributable to patient attrition from the study. Long-term economic evaluation suggested NMS may deliver better patient outcomes and reduced overall healthcare costs than normal practice, but uncertainty around this finding is high.</p><p><strong>Trial registration number: </strong>NCT01635361, ISRCTN23560818, ISRCTN23560818, UKCRN12494.</p>","PeriodicalId":49653,"journal":{"name":"Quality & Safety in Health Care","volume":"29 1","pages":"286-295"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45200310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dorothee Amelung, Katriina L Whitaker, Debby Lennard, Margaret Ogden, Jessica Sheringham, Yin Zhou, Fiona M Walter, Hardeep Singh, Charles Vincent, Georgia Black
{"title":"Influence of doctor-patient conversations on behaviours of patients presenting to primary care with new or persistent symptoms: a video observation study.","authors":"Dorothee Amelung, Katriina L Whitaker, Debby Lennard, Margaret Ogden, Jessica Sheringham, Yin Zhou, Fiona M Walter, Hardeep Singh, Charles Vincent, Georgia Black","doi":"10.1136/bmjqs-2019-009485","DOIUrl":"10.1136/bmjqs-2019-009485","url":null,"abstract":"<p><strong>Background: </strong>Most cancers are diagnosed following contact with primary care. Patients diagnosed with cancer often see their doctor multiple times with potentially relevant symptoms before being referred to see a specialist, suggesting missed opportunities during doctor-patient conversations.</p><p><strong>Objective: </strong>To understand doctor-patient communication around the significance of persistent or new presenting problems and its potential impact on timely cancer diagnosis.</p><p><strong>Research design: </strong>Qualitative thematic analysis based on video recordings of doctor-patient consultations in primary care and follow-up interviews with patients and doctors. 80 video observations, 20 patient interviews and 7 doctor interviews across 7 general practices in England.</p><p><strong>Results: </strong>We found that timeliness of diagnosis may be adversely affected if doctors and patients do not come to an agreement about the presenting problem's significance. 'Disagreements' may involve misaligned cognitive factors such as differences in medical knowledge between doctor and patient or misaligned emotional factors such as patients' unexpressed fear of diagnostic procedures. Interviews suggested that conversations where the difference in views is either not recognised or stays unresolved may lead to unhelpful patient behaviour after the consultation (eg, non-attendance at specialist appointments), creating potential for diagnostic delay and patient harm.</p><p><strong>Conclusions: </strong>Our findings highlight how doctor-patient consultations can impact timely diagnosis when patients present with persistent or new problems. Misalignments were common and could go unnoticed, leaving gaps for potential to cause patient harm. These findings have implications for timely diagnosis of cancer and other serious disease because they highlight the complexity and fluidity of the consultation and the subsequent impact on the diagnostic process.</p>","PeriodicalId":49653,"journal":{"name":"Quality & Safety in Health Care","volume":"29 1","pages":"198-208"},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47675551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ryan J Ellis, Cary Jo R Schlick, Joe Feinglass, Mary F Mulcahy, Al B Benson, Sheetal M Kircher, Tony D Yang, David D Odell, Karl Bilimoria, Ryan P Merkow
{"title":"Failure to administer recommended chemotherapy: acceptable variation or cancer care quality blind spot?","authors":"Ryan J Ellis, Cary Jo R Schlick, Joe Feinglass, Mary F Mulcahy, Al B Benson, Sheetal M Kircher, Tony D Yang, David D Odell, Karl Bilimoria, Ryan P Merkow","doi":"10.1136/bmjqs-2019-009742","DOIUrl":"10.1136/bmjqs-2019-009742","url":null,"abstract":"<p><strong>Background: </strong>Chemotherapy quality measures consider hospitals compliant when chemotherapy is recommended, even if it is not received. This may mask shortcomings in cancer care delivery. Objectives of this study were to (1) identify patient factors associated with failure to receive recommended chemotherapy without a documented contraindication and (2) assess hospital variation in failure to administer recommended chemotherapy.</p><p><strong>Methods: </strong>Patients from 2005 to 2015 with breast, colon and lung cancers who failed to receive recommended chemotherapy were identified using the National Cancer Database. Hospital-level rates of failure to administer recommended chemotherapy were calculated, and patient and hospital factors associated with failure to receive recommended chemotherapy were identified by multivariable logistic regression.</p><p><strong>Results: </strong>A total of 183 148 patients at 1281 hospitals were analysed. Overall, 3.5% of patients with breast, 6.6% with colon and 10.7% with lung cancers failed to receive recommended chemotherapy. Patients were less likely to receive recommended chemotherapy in all cancers if uninsured or on Medicaid (p<0.05), as were non-Hispanic black patients with both breast and colon cancer (p<0.001). Significant hospital variation was observed, with hospital-level rates of failure to administer recommended chemotherapy as high as 21.8% in breast, 40.2% in colon and 40.0% in lung cancers.</p><p><strong>Conclusions and relevance: </strong>Though overall rates are low, failure to receive recommended chemotherapy is associated with sociodemographic factors. Hospital variation in failure to administer recommended chemotherapy is masked by current quality measure definitions and may define a significant and unmeasured difference in hospital quality.</p>","PeriodicalId":49653,"journal":{"name":"Quality & Safety in Health Care","volume":"29 1","pages":"103-112"},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43874778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nikesh Parekh, Khalid Ali, John Graham Davies, Jennifer M Stevenson, Winston Banya, Stephen Nyangoma, Rebekah Schiff, Tischa van der Cammen, Jatinder Harchowal, Chakravarthi Rajkumar
{"title":"Medication-related harm in older adults following hospital discharge: development and validation of a prediction tool.","authors":"Nikesh Parekh, Khalid Ali, John Graham Davies, Jennifer M Stevenson, Winston Banya, Stephen Nyangoma, Rebekah Schiff, Tischa van der Cammen, Jatinder Harchowal, Chakravarthi Rajkumar","doi":"10.1136/bmjqs-2019-009587","DOIUrl":"10.1136/bmjqs-2019-009587","url":null,"abstract":"<p><strong>Objectives: </strong>To develop and validate a tool to predict the risk of an older adult experiencing medication-related harm (MRH) requiring healthcare use following hospital discharge.</p><p><strong>Design, setting, participants: </strong>Multicentre, prospective cohort study recruiting older adults (≥65 years) discharged from five UK teaching hospitals between 2013 and 2015.</p><p><strong>Primary outcome measure: </strong>Participants were followed up for 8 weeks in the community by senior pharmacists to identify MRH (adverse drug reactions, harm from non-adherence, harm from medication error). Three data sources provided MRH and healthcare use information: hospital readmissions, primary care use, participant telephone interview. Candidate variables for prognostic modelling were selected using two systematic reviews, the views of patients with MRH and an expert panel of clinicians. Multivariable logistic regression with backward elimination, based on the Akaike Information Criterion, was used to develop the PRIME tool. The tool was internally validated.</p><p><strong>Results: </strong>1116 out of 1280 recruited participants completed follow-up (87%). Uncertain MRH cases ('possible' and 'probable') were excluded, leaving a tool derivation cohort of 818. 119 (15%) participants experienced 'definite' MRH requiring healthcare use and 699 participants did not. Modelling resulted in a prediction tool with eight variables measured at hospital discharge: age, gender, antiplatelet drug, sodium level, antidiabetic drug, past adverse drug reaction, number of medicines, living alone. The tool's discrimination C-statistic was 0.69 (0.66 after validation) and showed good calibration. Decision curve analysis demonstrated the potential value of the tool to guide clinical decision making compared with alternative approaches.</p><p><strong>Conclusions: </strong>The PRIME tool could be used to identify older patients at high risk of MRH requiring healthcare use following hospital discharge. Prior to clinical use we recommend the tool's evaluation in other settings.</p>","PeriodicalId":49653,"journal":{"name":"Quality & Safety in Health Care","volume":"29 1","pages":"142-153"},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045783/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42781694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The illusion of perfection","authors":"P. Smulowitz","doi":"10.1136/bmjqs-2019-010501","DOIUrl":"https://doi.org/10.1136/bmjqs-2019-010501","url":null,"abstract":"Thirteen years ago, only a few months after completing my residency in emergency medicine, I walked into a night shift ready for anything. One of the first patients I encountered was a young man with right-sided thoracic back pain after having spent a day lifting moving boxes. Acute back pain is of course a common reason for people to visit an emergency department, and along with his age, the location and context of the pain seemed fairly typical for muscular strain. But as a junior attending I was appropriately more conservative than how I suspect I would act today. Responding to my nerves, an elicited history of cocaine use and leucocytosis, we ordered an MRI of the back to look for an epidural abscess and treated his pain.\u0000\u0000The MRI was performed and reported as a normal study. While we assessed whether he was comfortable for discharge, I proceeded to focus my attention on other patients who required immediate stabilisation and management. Sometime later during the shift I was suddenly startled by a low-pitched thud near my desk. I looked over and saw someone in a patient gown lying on the floor. Sprinting over to that spot, I soon realised it was this young man collapsed onto the floor in cardiac arrest. During the ongoing resuscitation, the proverbial light bulb went off in my head and I sent the resident physician back to speak with the radiologist again about the MRI, focusing specifically on the aorta. By the time we confirmed a type A aortic dissection ruptured into the right hemithorax and attempted to rush the patient to the operating room, it was too late.\u0000\u0000Despite our best efforts, he died.\u0000\u0000Nothing in my medical training up to that point prepared me for such failure. During medical school and residency …","PeriodicalId":49653,"journal":{"name":"Quality & Safety in Health Care","volume":"29 1","pages":"345 - 347"},"PeriodicalIF":0.0,"publicationDate":"2019-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmjqs-2019-010501","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48922408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}