Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery最新文献_第5页

Plexiform malignant peripheral nerve sheath tumour of infancy and childhood of the index finger: Surgical treatment. 婴幼儿食指丛状恶性周围神经鞘瘤:外科治疗。

Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery Pub Date : 2009-01-01 DOI: 10.1080/02844310701682998

Marcel F Meek, Rinze Wolf, J Henk Coert, Harald J Hoekstra, Jean-Philippe A Nicolai

引用次数: 1

Intermittent ischaemia of skin flaps shortens time taken to divide pedicles: an experimental study in rats. 皮瓣间歇性缺血可缩短大鼠皮蒂分裂时间。

Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery Pub Date : 2009-01-01 DOI: 10.3109/02844310903138906

Birol Civelek, Tayyar Selcuk, Esra Bilgen, Ercan Demirbag, Selim Celebioglu

引用次数: 10

Atypical Apert syndrome: sequential and segmental distraction osteogenesis of the skull, midface, and mandible. 非典型Apert综合征:颅骨、面中部和下颌骨的顺序和节段性牵张成骨。

Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery Pub Date : 2009-01-01 DOI: 10.1080/02844310701383993

Nobuyuki Mitsukawa, Kaneshige Satoh, Takashi Hayashi, Tadashi Morishita, Yoshiaki Hosaka

引用次数: 3

Advantages of open treatment for syndactyly of the foot: defining its indications. 足并指开放性治疗的优势:明确其适应症。

Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery Pub Date : 2009-01-01 DOI: 10.1080/02844310802556968

Makoto Hikosaka, Hisao Ogata, Tatsuo Nakajima, Hisashi Kobayashi, Noriko Hattori, Fumio Onishi, Ikkei Tamada

引用次数: 12

Magnesium sulphate given topically by iontophoresis for viability of random skin flaps in rats. 离子导入法局部给予硫酸镁对大鼠随机皮瓣存活率的影响。

Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery Pub Date : 2009-01-01 DOI: 10.1080/02844310902840122

Renato André Yu, Christine Brumini, Ivaldo Esteves Junior, Lydia Masako Ferreira, Richard Eloin Liebano

{"title":"Magnesium sulphate given topically by iontophoresis for viability of random skin flaps in rats.","authors":"Renato André Yu, Christine Brumini, Ivaldo Esteves Junior, Lydia Masako Ferreira, Richard Eloin Liebano","doi":"10.1080/02844310902840122","DOIUrl":"https://doi.org/10.1080/02844310902840122","url":null,"abstract":"Our aim was to assess the effects of magnesium sulphate given by iontophoresis on the viability of random skin flaps in rats. Endovenous magnesium sulphate is used to treat pre-eclampsia and diseases of blood vessels. Iontophoresis is an electrotherapeutic method which has shown satisfactory results in controlling ischaemia within the boundaries of the area in which it was given. Forty-five adult male Wistar rats, weighing 300 to 440 g were randomly divided into three groups of 15 animals each: random skin flap (control); random skin flap treated with magnesium sulphate without electrical stimulation; and random skin flap treated with magnesium sulphate with electrical stimulation of 4 mA for 20 minutes. The treatments were applied immediately after the operation and repeated on the following two days. The percentage of necrotic area was measured on the seventh postoperative day using a paper template. For each group, the mean percentage of flap necrosis was as follows: control, 46%; magnesium sulphate without electrical stimulation, 34%; and magnesium sulphate with electrical stimulation, 42%. There was no significant difference among the groups (p = 0.18). Magnesium sulphate given by iontophoresis does not increase the viability of random skin flaps in rats.","PeriodicalId":49569,"journal":{"name":"Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery","volume":"43 4","pages":"197-200"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/02844310902840122","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28347786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Mammary myocutaneous-glandular flap for reconstruction of oncological defects of the anterior midline chest wall. 乳腺肌腺瓣重建胸壁前中线肿瘤缺损。

Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery Pub Date : 2009-01-01 DOI: 10.1080/02844310701514241

Bishara S Atiyeh, Pierre M Sfeir, Shady N Hayek

引用次数: 2

Germline mutation screening of the Saethre-Chotzen-associated genes TWIST1 and FGFR3 in families with BRCA1/2-negative breast cancer. brca1 /2阴性乳腺癌家族中saethree - chotzen相关基因TWIST1和FGFR3的种系突变筛查

Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery Pub Date : 2009-01-01 DOI: 10.3109/02844310903247228

Annika Bergman, Pelle Sahlin, Monica Emanuelsson, Helena Carén, Peter Tarnow, Tommy Martinsson, Henrik Grönberg, Göran Stenman

{"title":"Germline mutation screening of the Saethre-Chotzen-associated genes TWIST1 and FGFR3 in families with BRCA1/2-negative breast cancer.","authors":"Annika Bergman, Pelle Sahlin, Monica Emanuelsson, Helena Carén, Peter Tarnow, Tommy Martinsson, Henrik Grönberg, Göran Stenman","doi":"10.3109/02844310903247228","DOIUrl":"https://doi.org/10.3109/02844310903247228","url":null,"abstract":"Saethre-Chotzen syndrome is one of the most common craniosynostosis syndromes. It is an autosomal dominantly inherited disorder with variable expression that is caused by germline mutations in the TWIST1 gene or more rarely in the FGFR2 or FGFR3 genes. We have previously reported that patients with Saethre-Chotzen syndrome have an increased risk of developing breast cancer. Here we have analysed a cohort of 26 women with BRCA1/2-negative hereditary breast cancer to study whether a proportion of these families might have mutations in Saethre-Chotzen-associated genes. DNA sequence analysis of TWIST1 showed no pathogenic mutations in the coding sequence in any of the 26 patients. MLPA (multiplex ligation-dependent probe amplification)-analysis also showed no alterations in copy numbers in any of the craniofacial disorder genes MSX2, ALX4, RUNX2, EFNB1, TWIST1, FGFR1, FGFR2,FGFR3, or FGFR4. Taken together, our findings indicate that mutations in Saethre-Chotzen-associated genes are uncommon or absent in BRCA1/2-negative patients with hereditary breast cancer.","PeriodicalId":49569,"journal":{"name":"Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery","volume":"43 5","pages":"251-5"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02844310903247228","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28464082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Placebo-controlled trial of local anaesthesia for treatment of pain after breast reconstruction. 局部麻醉治疗乳房再造术后疼痛的安慰剂对照试验。

Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery Pub Date : 2009-01-01 DOI: 10.1080/02844310903259108

Mariann Legeby, Göran Jurell, Marianne Beausang-Linder, Christina Olofsson

{"title":"Placebo-controlled trial of local anaesthesia for treatment of pain after breast reconstruction.","authors":"Mariann Legeby, Göran Jurell, Marianne Beausang-Linder, Christina Olofsson","doi":"10.1080/02844310903259108","DOIUrl":"https://doi.org/10.1080/02844310903259108","url":null,"abstract":"Breast reconstruction with submuscular tissue implants is associated with substantial postoperative pain. High pain scores despite large doses of opioids were described in earlier studies, which indicated that opioids alone or together with paracetamol are insufficient. In the present placebo-controlled study we aimed to evaluate the analgesic efficacy of local anaesthesia as a supplement. Forty-three women who had previously been operated on for breast cancer and were listed for unilateral secondary breast reconstruction were assigned at random to one of two groups. The patients received 2.5 mg/ml levobupivacaine (Chirocaine) 15 ml or placebo in a double-blind manner through an indwelling catheter in the operation site every three hours for 45 hours. All patients were given oral paracetamol 1 g x 4 orally and morphine intravenously as patient-controlled analgesia. A visual analogue scale (VAS) was used to assess the intensity of the postoperative pain. Amount of morphine used was recorded. The women in the levobupivacaine group (n=21) reported significantly less pain at rest during the first 15 hours postoperatively (p<0.05). During mobilisation the intensity of pain was lower for the first six hours (p=0.01) and for the interval 18-24 hours (p=0.045) in the same group. Total mean (SD) consumption of opioids in the levobupivacaine and placebo groups was 24.6 mg (22.88) and 33.8 mg (30.82), respectively (p=0.28). After reconstruction, levobupivacaine injected locally every third hour as a supplement to paracetamol orally and morphine given by PCA resulted in improved pain relief at rest and during mobilisation. Morphine consumption was reduced, but this was not significant (p=0.28).","PeriodicalId":49569,"journal":{"name":"Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery","volume":"43 6","pages":"315-9"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/02844310903259108","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28580990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

Extension or combination of an autologous latissimus dorsi flap in breast reconstruction. 自体背阔肌皮瓣在乳房再造术中的应用。

Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery Pub Date : 2009-01-01 DOI: 10.1080/02844310802489285

Jonas Lundberg

引用次数: 7

Immunohistochemical evidence for Zic1 coexpression with beta-catenin in the myofibroblast of Dupuytren disease. Dupuytren病肌成纤维细胞中Zic1与β -连环蛋白共表达的免疫组织化学证据

Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery Pub Date : 2009-01-01 DOI: 10.1080/02844310802489806

Ilse Degreef, Luc De Smet, Raf Sciot, Jean-Jacques Cassiman, Sabine Tejpar

{"title":"Immunohistochemical evidence for Zic1 coexpression with beta-catenin in the myofibroblast of Dupuytren disease.","authors":"Ilse Degreef, Luc De Smet, Raf Sciot, Jean-Jacques Cassiman, Sabine Tejpar","doi":"10.1080/02844310802489806","DOIUrl":"https://doi.org/10.1080/02844310802489806","url":null,"abstract":"The active cellular component in Dupuytren disease (DD) is the alpha-smooth muscle actin (alpha-SMA) containing myofibroblast. The underlying regulatory processes in activation of myofibroblasts resemble the pathophysiology of certain types of cancer. Accumulation of beta-catenin has been shown in many fibroproliferative processes, including DD and, recent findings attributed a possible role to the Zic1 transcription factor. To assess Zic1 expression in DD and investigate its relation with the accumulation of beta-catenin, neighbouring tissue samples in 20 patients with DD were stained immunohistochemically with monoclonal antibodies for beta-catenin, alpha-SMA, and Zic1. Histological appearance was staged according to Luck. Cell-rich areas with accumulation of beta-catenin in myofibroblasts that stained for alpha-SMA and showed apparent Zic1 coexpression were obvious. This coexpression seemed independent of proliferative or involutional histological staging. We found only Zic1 expression in residual stages. A different pattern of expression of protein in the residual stage may support earlier suggestions of a cellular heterogeneity with the existence of different cell (sub-)populations in nodules and cords. On the other hand coexpression of Zic1 and beta-catenin may indicate a relation between Zic1 and the Wnt-pathway. Further studies are needed to elucidate cellular origin, potential heterogeneity and activity of the myofibroblasts in DD, and to define the exact role of Zic1 in fibroproliferative processes, wound healing, and cancer. The fibroblast in DD is an interesting model for future experiments.","PeriodicalId":49569,"journal":{"name":"Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery","volume":"43 1","pages":"36-40"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/02844310802489806","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27932529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21