R. Wesley Vosburg M.D. , Abdelrahman Nimeri M.D. , Dan Azagury M.D. , Brandon Grover M.D. , Sabrena Noria M.D. , Pavlos Papasavas M.D. , Jonathan Carter M.D.
{"title":"American Society for Metabolic and Bariatric Surgery literature review on risk factors, screening recommendations, and prophylaxis for marginal ulcers after metabolic and bariatric surgery","authors":"R. Wesley Vosburg M.D. , Abdelrahman Nimeri M.D. , Dan Azagury M.D. , Brandon Grover M.D. , Sabrena Noria M.D. , Pavlos Papasavas M.D. , Jonathan Carter M.D.","doi":"10.1016/j.soard.2024.10.013","DOIUrl":"10.1016/j.soard.2024.10.013","url":null,"abstract":"<div><h3>Background</h3><div>Marginal ulcers (MU) are a significant postoperative complication following anastomotic metabolic and bariatric surgeries including Roux-en-Y gastric bypass (RYGB), one-anastomosis gastric bypass (OAGB), and biliopancreatic diversion with duodenal switch (BPD/DS). This review summarizes current knowledge on MU risk factors, screening, and prophylactic strategies.</div></div><div><h3>Objectives</h3><div>The goal of this review is to examine technical and patient-related risk factors for MU, assess screening strategies, and recommend prophylactic approaches to reduce MU incidence after anastomotic metabolic and bariatric surgery (MBS).</div></div><div><h3>Setting</h3><div>A comprehensive review was conducted by members of the American Society for Metabolic and Bariatric Surgery (ASMBS) Clinical Issues Committee, based on available literature from 2000 to the present.</div></div><div><h3>Methods</h3><div>A systematic search was performed using Ovid MEDLINE and PubMed databases. Relevant studies were screened for inclusion. Technical and patient-related factors were evaluated, and recommendations for MU prevention were formulated.</div></div><div><h3>Results</h3><div>Several risk factors for MU were identified, including large gastric pouch size, circular stapled anastomoses, use of nonabsorbable sutures, smoking, nonsteroidal anti-inflammatory drugs use, and immunosuppression. While prophylactic proton pump inhibitor (PPI) therapy is widely recommended, its optimal duration remains debated. The role of <em>Helicobacter pylori</em> in MU development is not clearly defined.</div></div><div><h3>Conclusions</h3><div>Prophylactic PPI therapy for at least 3 months postsurgery significantly reduces the risk of MU. Risk stratification and individualized treatment plans are essential to minimize postoperative complications. Further research is needed to clarify the role of <em>H. pylori</em> and optimize prophylactic strategies.</div></div>","PeriodicalId":49462,"journal":{"name":"Surgery for Obesity and Related Diseases","volume":"21 2","pages":"Pages 101-108"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Utilization patterns of glucagon like Peptide-1 receptor agonists prior to bariatric and metabolic surgery: a multicenter study","authors":"Shlomi Rayman M.D. , Evyatar Morduch , Anat Reiner-Benaim Ph.D. , Netta-lee Catzman R.N., M.N. , Idan Carmeli M.D. , Dvir Froylich M.D. , David Goitein","doi":"10.1016/j.soard.2024.09.010","DOIUrl":"10.1016/j.soard.2024.09.010","url":null,"abstract":"<div><h3>Background</h3><div>Glucagon-like-peptide-1 receptor agonists (G1RA) have gained popularity as a treatment for weight loss in patients who are overweight or obese, but their utilization patterns and impact on candidates for metabolic and bariatric surgery (MBS) remain understudied.</div></div><div><h3>Objective</h3><div>We aimed to investigate the prevalence, characteristics, and outcomes of patients with a history of G1RA utilization among MBS candidates.</div></div><div><h3>Setting</h3><div>Five high-volume MBS centers in Israel.</div></div><div><h3>Methods</h3><div>Data were collected retrospectively from February 1st, 2023, to September 30th, 2023. Demographic, clinical, and treatment data were analyzed to assess a history of G1RA use, associated factors, adverse events, and treatment outcomes.</div></div><div><h3>Results</h3><div>Four hundred thirty-four MBS candidates were included in the study. A history of G1RA utilization was obtained in 275 (63%) MBS candidates, with Liraglutide and Semaglutide being the most commonly used agents. Younger age, type 2 diabetes mellitus, dyslipidemia, and no previous MBS history were associated with a higher rate of G1RA utilization. With these medications, median maximal weight loss was 5.38 kg, and mean duration of use was 19 weeks. Patients using G1RA for ≥6 weeks experienced significantly greater weight loss compared to those using it for shorter periods (6.3 ± 6.43 vs 1.65 ± 1.69; <em>P</em> < .001). GI-related adverse events were reported in 57.8% of patients. Over 95% of patients discontinued G1RA due to insufficient weight loss and/or adverse effects. Patients reaching the maximal recommended dose exhibited significantly greater weight loss versus patients who did not reach it for both Liraglutide (5.9 ± 4.98 kg vs. 3.9 ± 5.53 kg; <em>P</em> = .03) and Semaglutide (6.5 ± 7.8 kg vs. 2.5 ± 3.8 kg; <em>P</em> = .016).</div></div><div><h3>Conclusion</h3><div>Pre-MBS G1RA utilization and failure are prevalent among MBS candidates. Our study underscores the need for further research to understand the role of G1RA therapy in obesity management and the development of guidelines for its appropriate use in MBS candidates.</div></div>","PeriodicalId":49462,"journal":{"name":"Surgery for Obesity and Related Diseases","volume":"21 2","pages":"Pages 121-126"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael A. Edwards M.D. , Kinga Powers M.D. , R. Wesley Vosburg M.D. , Randal Zhou M.D. , Andrea Stroud M.D. , Nabeel R. Obeid M.D. , John Pilcher M.D. , Shauna Levy M.D. , Karina McArthur M.D. , Givi Basishvili , Amy Rosenbluth , Anthony Petrick , Henry Lin M.D. , Tammy Kindel M.D., Ph.D.
{"title":"American Society for Metabolic and Bariatric Surgery: postoperative care pathway guidelines for Roux-en-Y gastric bypass","authors":"Michael A. Edwards M.D. , Kinga Powers M.D. , R. Wesley Vosburg M.D. , Randal Zhou M.D. , Andrea Stroud M.D. , Nabeel R. Obeid M.D. , John Pilcher M.D. , Shauna Levy M.D. , Karina McArthur M.D. , Givi Basishvili , Amy Rosenbluth , Anthony Petrick , Henry Lin M.D. , Tammy Kindel M.D., Ph.D.","doi":"10.1016/j.soard.2025.01.005","DOIUrl":"10.1016/j.soard.2025.01.005","url":null,"abstract":"<div><h3>Background</h3><div>Clinical care pathways and guidelines help guide and provide structure to clinicians and providers to improve healthcare delivery and quality. The Quality Improvement and Patient Safety (QIPS) Committee of the American Society for Metabolic and Bariatric Surgery (ASMBS) has previously published care pathways for the performance of laparoscopic sleeve gastrectomy (LSG), preoperative care of patients undergoing Roux-en-Y gastric bypass (RYGB), and most recently, intraoperative care of patients undergoing RYGB.</div></div><div><h3>Objectives</h3><div>This current RYGB care pathway guideline was created to address postoperative care guidance.</div></div><div><h3>Setting</h3><div>Academic Health Center.</div></div><div><h3>Methods</h3><div>For this systematic review, PubMed queries were performed from January 1979 to December 2019. Follow-up queries were performed from January 2020 to July 2024. Peer-reviewed publications were reviewed according to the level of evidence (LoE) regarding specific key questions developed by the QIPS Committee and working group for this pathway.</div></div><div><h3>Results</h3><div>Evidence-based recommendations are made for the postoperative care of patients undergoing RYGB, including recommendations for early postoperative care, postoperative medication management, and long-term postoperative surveillance.</div></div><div><h3>Conclusions</h3><div>This document may provide a structure to providers based on current evidence for the postoperative care of patients with overweight or obesity undergoing RYGB.</div></div>","PeriodicalId":49462,"journal":{"name":"Surgery for Obesity and Related Diseases","volume":"21 5","pages":"Pages 523-536"},"PeriodicalIF":3.5,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgical management of candy cane syndrome after Roux-en-Y gastric bypass","authors":"Hassan Nasser M.D.","doi":"10.1016/j.soard.2024.12.019","DOIUrl":"10.1016/j.soard.2024.12.019","url":null,"abstract":"","PeriodicalId":49462,"journal":{"name":"Surgery for Obesity and Related Diseases","volume":"21 4","pages":"Page e12"},"PeriodicalIF":3.5,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yasamin Taghikhan D.O., Victoria Lyo M.D., M.T.M., F.A.C.S.
{"title":"Comment on: Pregnancy and birth complications among women undergoing bariatric surgery: sleeve gastrectomy versus Roux-en-Y gastric bypass","authors":"Yasamin Taghikhan D.O., Victoria Lyo M.D., M.T.M., F.A.C.S.","doi":"10.1016/j.soard.2024.12.020","DOIUrl":"10.1016/j.soard.2024.12.020","url":null,"abstract":"","PeriodicalId":49462,"journal":{"name":"Surgery for Obesity and Related Diseases","volume":"21 4","pages":"Pages e13-e14"},"PeriodicalIF":3.5,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143043928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comments on: Bariatric surgery targeting opioid prescribing: a national model for effectively reducing opioid use after bariatric surgery","authors":"Lee Ying M.D., Ph.D., M.S., M.Phil., Saber Ghiassi M.D., M.P.H., F.A.C.S., F.A.S.M.B.S.","doi":"10.1016/j.soard.2024.12.021","DOIUrl":"10.1016/j.soard.2024.12.021","url":null,"abstract":"","PeriodicalId":49462,"journal":{"name":"Surgery for Obesity and Related Diseases","volume":"21 4","pages":"Pages 410-411"},"PeriodicalIF":3.5,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143049368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on: Pregnancy and birth complications among women undergoing bariatric surgery: sleeve gastrectomy versus Roux-en-Y gastric bypass","authors":"L. Renee Hilton M.D.","doi":"10.1016/j.soard.2024.12.018","DOIUrl":"10.1016/j.soard.2024.12.018","url":null,"abstract":"","PeriodicalId":49462,"journal":{"name":"Surgery for Obesity and Related Diseases","volume":"21 4","pages":"Pages e10-e11"},"PeriodicalIF":3.5,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143070546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Imen Becetti M.D. , Ana Paola Lopez Lopez M.D. , Francesca Galbiati M.D. , Clarissa C. Pedreira M.D. , Meghan Lauze B.S. , Karen Olivar Carreno M.D. , Florian A. Huber M.D. , Olivier Bitoun M.D. , Hang Lee Ph.D. , Brian Carmine M.D. , Vibha Singhal M.D., M.P.H. , Madhusmita Misra M.D., M.P.H. , Miriam A. Bredella M.D., M.B.A.
{"title":"Changes in pancreatic steatosis by computed tomography 24 months after sleeve gastrectomy in youth with severe obesity","authors":"Imen Becetti M.D. , Ana Paola Lopez Lopez M.D. , Francesca Galbiati M.D. , Clarissa C. Pedreira M.D. , Meghan Lauze B.S. , Karen Olivar Carreno M.D. , Florian A. Huber M.D. , Olivier Bitoun M.D. , Hang Lee Ph.D. , Brian Carmine M.D. , Vibha Singhal M.D., M.P.H. , Madhusmita Misra M.D., M.P.H. , Miriam A. Bredella M.D., M.B.A.","doi":"10.1016/j.soard.2024.08.034","DOIUrl":"10.1016/j.soard.2024.08.034","url":null,"abstract":"<div><h3>Background</h3><div>Pancreatic steatosis has been associated with obesity and the metabolic syndrome. Studies in adults have demonstrated improvement in pancreatic steatosis following sleeve gastrectomy (SG) with concomitant improvement in glucose homeostasis.</div></div><div><h3>Objectives</h3><div>To examine changes in pancreatic steatosis in youth with severe obesity 24 months following SG.</div></div><div><h3>Setting</h3><div>Academic hospital system.</div></div><div><h3>Methods</h3><div>Forty-seven youth (13–24 years) with severe obesity (37 females) were followed for 24 months; 23 had SG and 24 were nonsurgical (NS) controls. Attenuations of the pancreas and spleen were measured using computed tomography (CT) at baseline, 12- and 24-month follow-up. Subjects underwent magnetic resonance imaging (MRI) for subcutaneous and visceral adipose tissue (SAT, VAT), dual energy x-ray absorptiometry (DXA) for body composition, blood sampling for glycated hemoglobin (A1C), and fasting and postprandial insulin and glucose. Linear mixed effects (LMEs) models were used to compare within- and between-group changes over 24 months.</div></div><div><h3>Results</h3><div>At baseline, SG had higher body mass index (BMI) versus NS (<em>P</em> = .033). Over 24 months, significant reductions were noted in weight, BMI, VAT, SAT, fat mass (FM), and lean mass (LM) in the SG versus NS groups (<em>P</em> ≤ .0001). There was a significant 24-month decrease in pancreatic steatosis in the SG group (<em>P</em> = .006). In the whole group, 24-month reductions in pancreatic steatosis correlated with BMI and FM decreases. No associations were found between pancreatic steatosis and glucose homeostasis parameters.</div></div><div><h3>Conclusions</h3><div>Pancreatic steatosis measured by CT improved after SG in youth. Further studies are needed to understand the relationship between pancreatic steatosis and glucose homeostasis.</div></div>","PeriodicalId":49462,"journal":{"name":"Surgery for Obesity and Related Diseases","volume":"21 1","pages":"Pages 59-66"},"PeriodicalIF":3.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142368116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The relationship of decision regret with quality of life and comfort level in patients undergoing laparoscopic sleeve gastrectomy: a cross-sectional study","authors":"Tülay Kılınç Ph.D. , Ayşegül Yayla Ph.D. , Zeynep Karaman Özlü Ph.D. , Duygu Balaban M.Sc.","doi":"10.1016/j.soard.2024.08.030","DOIUrl":"10.1016/j.soard.2024.08.030","url":null,"abstract":"<div><h3>Background</h3><div>Laparoscopic sleeve gastrectomy (SG) is one of the effective methods of weight loss. It is essential to determine patients' regret and predictive factors to improve their quality of life and comfort. No study has investigated decision regret and affecting factors in patients undergoing SG in Turkey.</div></div><div><h3>Objectives</h3><div>The study aimed to determine the relationship of decision regret with quality of life and comfort level in patients undergoing SG.</div></div><div><h3>Setting</h3><div>The research was carried out with patients who had undergone SG in a private hospital in the west of Turkey.</div></div><div><h3>Methods</h3><div>The research was conducted as a descriptive, correlational, and cross-sectional study. Data were collected between March and May 2023, and the study was completed with 286 patients. Data were collected using the Personal Information Form, Decision Regret Scale (DRS), Quality of Life Following Obesity Surgery Scale (QoL-OS), and Comfort Scale.</div></div><div><h3>Results</h3><div>Patients’ mean score on the DRS was 5.27 ± 13.41 (0-100), the total mean score on the QoL-OS-Biopsychosocial dimension was 79.57 ± 9.35 (18-90), the mean score on the QoL-OS-Complications dimension was 17.17 ± 4.60 (7-35), and the environmental comfort score average was 8.87 ± 2.23 (0-10). Patients’ decision regret was significantly affected by the QoL-OS-Biopsychosocial Area dimension in the first place (Beta = −.516; <em>P</em> < .001), social comfort in the second place (Beta = −.278; <em>P</em> < .001), postoperative weight gain in the third place (Beta = .221; <em>P</em> < .001), and complication development in the fourth place (Beta = .163; <em>P</em> < .001).</div></div><div><h3>Conclusions</h3><div>The study revealed that patients’ decision regret levels were very low up to 3 years after surgery and found that low postoperative quality of life and social comfort level, postoperative weight gain, and complications affected decision regret.</div></div>","PeriodicalId":49462,"journal":{"name":"Surgery for Obesity and Related Diseases","volume":"21 1","pages":"Pages 41-51"},"PeriodicalIF":3.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142376492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hugo Sandoval Ph.D. , Benjamin Clapp M.D. , Laura E. O’Dell Ph.D. , Deborah J. Clegg Ph.D.
{"title":"A review of brain structural and functional changes using MRI technology in patients who received bariatric surgery","authors":"Hugo Sandoval Ph.D. , Benjamin Clapp M.D. , Laura E. O’Dell Ph.D. , Deborah J. Clegg Ph.D.","doi":"10.1016/j.soard.2024.08.036","DOIUrl":"10.1016/j.soard.2024.08.036","url":null,"abstract":"<div><div>According to the World Health Organization, obesity is one of the most significant health issues currently because it increases risk for type 2 diabetes and cancer, heart disease, bone health, reproduction, and quality of living and it impacts approximately 500 million adults worldwide. This review analyzed the existing literature focusing on the effects of Metabolic and bariatric surgeries (MBS), including Roux-en-Y gastric bypass and sleeve gastrectomy on changes in brain function and anatomy using magnetic resonance imaging (MRI) technology. A PubMed search using the key words <em>bariatric surgery</em> and <em>MRI</em> conducted in December 2023 resulted in 544 articles. Our literature review identified 24 studies addressing neuroanatomic, neurophysiological, cognitive, and behavioral changes that occurred at different time intervals after different types of bariatric surgery. Our review of the literature found several reports indicating that MBS reverse neuroanatomic alterations and changes in functional connectivity associated with obesity. There were also reported improvements in cognitive performance, memory, executive function, attention, as well as decreased gustatory brain responses to food cues and resting state measures following bariatric surgery. There were instances of improved neural functioning associated with weight loss, suggesting that some neuroanatomic changes can be reversed following weight loss induced by bariatric surgery. Additionally, there were data suggesting that brain connectivity and metabolic health are improved following a bariatric surgical intervention. Together, the existing literature indicates an overall improvement in brain connectivity and health outcomes following bariatric surgery.</div></div>","PeriodicalId":49462,"journal":{"name":"Surgery for Obesity and Related Diseases","volume":"21 1","pages":"Pages 85-92"},"PeriodicalIF":3.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142368115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}