Journal of health sciences and innovative research最新文献

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Correlation of Atherogenic Index of Plasma and Atherogenic Coefficient with Cardiovascular Disease Risk assessed by ASCVD Risk Calculator 用ASCVD风险计算器评估血浆动脉粥样硬化指数和动脉粥样硬化系数与心血管疾病风险的相关性

Journal of health sciences and innovative research Pub Date : 2023-11-08 DOI: 10.31357/jhsir.v4i01.6329

Rahal Widanagamage, None K.H.M. Silva, None H.A.C. Ayeshmantha, None K.U.G.D.M. Kariyawasam, None R.A.N.K. Wijesinghe

{"title":"Correlation of Atherogenic Index of Plasma and Atherogenic Coefficient with Cardiovascular Disease Risk assessed by ASCVD Risk Calculator","authors":"Rahal Widanagamage, None K.H.M. Silva, None H.A.C. Ayeshmantha, None K.U.G.D.M. Kariyawasam, None R.A.N.K. Wijesinghe","doi":"10.31357/jhsir.v4i01.6329","DOIUrl":"https://doi.org/10.31357/jhsir.v4i01.6329","url":null,"abstract":"Introduction: Cardiovascular disease (CVD) is the leading cause of approximately one-third deaths worldwide. Absolute lipid parameters are inadequate in predicting CVD risk and several lipid indices have been introduced namely “Atherogenic index of plasma” (AIP) and “Atherogenic coefficient” (AC). CVD risk of a patient for the upcoming 10 years can be calculated using atherosclerotic cardiovascular disease (ASCVD) risk calculator. Though, this method currently accepts as the gold standard, certain drawbacks have been reported. Therefore, the aim of this study was to investigate the correlation of AIP and AC with CVD risk estimation for the upcoming 10 years calculated by ASCVD risk calculator. Methods: Hundred and fifty-three patients were recruited for the study. Socio-demographic data were collected through interviewer-based questionnaire. Total cholesterol, HDL cholesterol, LDL cholesterol and triglycerides values were obtained from the lipid profile test results of the study participants. AIP and AC were calculated using formulas while 10-year ASCVD risk was calculated by ASCVD risk calculator. Results: There was no significant correlation between AIP and 10-year ASCVD risk (p>0.05) and AC and 10-year ASCVD risk (p>0.05), but a significant correlation was observed between AIP and AC (Pearson’s correlation r=0.425, p<0.05). Conclusions: CVD risk of patients should be assessed routinely especially as it is overlooked in most patients presenting normal lipid profile variables, hence the actual risk remains silent unless it is properly investigated using laboratory investigations","PeriodicalId":493801,"journal":{"name":"Journal of health sciences and innovative research","volume":"184 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135342289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bicuspidization: salvaging a mandibular molar with endo-periodontal lesion 双尖牙拔除术:修复牙周内病变的下颌磨牙

Journal of health sciences and innovative research Pub Date : 2023-11-08 DOI: 10.31357/jhsir.v4i01.6390

Samudi Sathsara Kalubowila, Priyake Palipana

引用次数: 0

Association of selected inflammatory markers and risk factors with pain in patients undergoing cervical or lumbar disc herniation 选定的炎症标志物和危险因素与颈椎或腰椎间盘突出症患者疼痛的关系

Journal of health sciences and innovative research Pub Date : 2023-11-08 DOI: 10.31357/jhsir.v4i01.6395

N D Withanage, Imrana Farook, Rajith Priyankara, Deepal Attanayake, Pathirana Dias, Lohini Athiththan

{"title":"Association of selected inflammatory markers and risk factors with pain in patients undergoing cervical or lumbar disc herniation","authors":"N D Withanage, Imrana Farook, Rajith Priyankara, Deepal Attanayake, Pathirana Dias, Lohini Athiththan","doi":"10.31357/jhsir.v4i01.6395","DOIUrl":"https://doi.org/10.31357/jhsir.v4i01.6395","url":null,"abstract":"Introduction Studies have suggested that radicular pain following disc herniation may be associated with local or systemic inflammatory responses produced in the vicinity of the herniated disc rather than compression of the nerve. Present study assessed the association of serum interleukin-6 (IL-6) levels, high-sensitivity C-reactive protein (hs-CRP) and related risk factors in patients undergoing discectomy following cervical disc herniation (CDH) or lumbar disc herniation (LDH). Methods Study recruited 77 patients undergoing discectomy for LDH and CDH. An interviewer administered questionnaire was used to obtain sociodemographic, behavioral and occupational data. IL-6 and hs-CRP levels were measured in each individual. IL-6 was analyzed by ELISA method and hs-CRP was determined using auto analyzer. Results were analyzed by using SPSS version 25.0.  Results Significant correlation was not found with serum IL-6 and hs-CRP levels (r=0.02, p˃0.05) for acute and chronic CDH and LDH. Patients with chronic neck or back pain showed significantly (p=0.043) higher IL-6 level compared to patients with acute neck or back pain. Serum hs-CRP level was significantly higher (p=0.048) in patients with acute neck or back pain compared to patients with chronic neck or back pain. Significant association was not observed between; level of physically demanding nature of occupation (p=0.542), duration of occupation (p=0.446), type of exercise (p=0.371), type of sports (p=0.339) and CDH or LDH. Conclusion Though significant correlation was not observed between inflammatory markers IL-6, hs-CRP and CDH or LDH. The mean IL-6 was higher in chronic back pain and neck pain patients with LDH and CDH whereas mean hs-CRP mean was higher in acute back pain and neck pain patients. Significant association was not reported between selected known risk factors (behavioral, occupational) and CDH or LDH.","PeriodicalId":493801,"journal":{"name":"Journal of health sciences and innovative research","volume":"25 28","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135391557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0