Carmen María Marín Marín , Paloma García Moreno , Raúl Vicho Pereira
{"title":"Diagnóstico de colitis por ecografía en una Unidad de Cuidados Intensivos","authors":"Carmen María Marín Marín , Paloma García Moreno , Raúl Vicho Pereira","doi":"10.1016/j.medin.2024.502115","DOIUrl":"10.1016/j.medin.2024.502115","url":null,"abstract":"","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"49 7","pages":"Article 502115"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144522515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Predictive performance of ROX index and its variations for NIV failure","authors":"Lada Lijović , Tomislav Radočaj , Nataša Kovač , Marinko Vučić , Paul Elbers","doi":"10.1016/j.medin.2024.502136","DOIUrl":"10.1016/j.medin.2024.502136","url":null,"abstract":"<div><h3>Objective</h3><div>To determine whether the ROX index and its variations can predict the risk of intubation in ICU patients receiving NIV ventilation using large public ICU databases.</div></div><div><h3>Design</h3><div>Retrospective observational cohort study.</div></div><div><h3>Setting</h3><div>Patient data was extracted from both the AmsterdamUMCdb and the MIMIC-IV ICU databases, which contained data related to 20,109 and 50,920 unique patients.</div></div><div><h3>Patients</h3><div>Non-invasively mechanically ventilated.</div></div><div><h3>Interventions</h3><div>Retrospective review of variables.</div></div><div><h3>Main variables of interest</h3><div>To assess the predictive values of models for each index, the ROX and its variations mROX, ROX-HR and mROX-HR were calculated based on mean values of SpO<sub>2</sub>, respiratory rate, FiO<sub>2</sub> and PaO<sub>2</sub> from 2-h windows within the first 12 h of NIV.</div></div><div><h3>Results</h3><div>3344 patients were eligible for analysis of which 1344 were intubated, died or returned to NIV within 24 h of ending NIV. NIV failure group had higher SOFA scores and higher CRP levels at admission. There was no difference in duration of NIV therapy or 28-day mortality, but patients who failed NIV had longer length of stay. The best performing index was ROX with an AUROC of 0.626 at 10−12 h. All other indices for all other time windows were less discriminating.</div></div><div><h3>Conclusions</h3><div>The performance of ROX index and its variations to predict NIV failure in ICU patients across large public ICU databases was moderate at best and cannot currently be recommended for clinical decision support.</div></div>","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"49 7","pages":"Article 502136"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144522453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Esteban Fernández-Hinojosa , María Adriaensens Pérez , José Cayetano Naranjo Jarillo
{"title":"Innovación tecnológica en cuidados intensivos y los límites de la vida","authors":"Esteban Fernández-Hinojosa , María Adriaensens Pérez , José Cayetano Naranjo Jarillo","doi":"10.1016/j.medin.2025.502153","DOIUrl":"10.1016/j.medin.2025.502153","url":null,"abstract":"","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"49 6","pages":"Article 502153"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cristiane Bastos Netto , Maycon Moura Reboredo , Rodrigo Souza Vieira , Lídia Maria Carneiro da Fonseca , Elivaldo Cyrillo Júnior , André Luís Dias de Souza , Erich Vidal Carvalho , Bruno Valle Pinheiro
{"title":"The impact of mechanical insufflation-exsufflation on the weaning success rate of tracheostomized patients on prolonged mechanical ventilation: a pilot and feasibility study of a randomized controlled trial","authors":"Cristiane Bastos Netto , Maycon Moura Reboredo , Rodrigo Souza Vieira , Lídia Maria Carneiro da Fonseca , Elivaldo Cyrillo Júnior , André Luís Dias de Souza , Erich Vidal Carvalho , Bruno Valle Pinheiro","doi":"10.1016/j.medin.2024.502125","DOIUrl":"10.1016/j.medin.2024.502125","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the feasibility of adding mechanical insufflation-exsufflation (MI-E) to a weaning protocol for tracheostomized patients undergoing prolonged mechanical ventilation (MV).</div></div><div><h3>Design</h3><div>Single-center, open-label, randomized, controlled pilot and feasibility study.</div></div><div><h3>Setting</h3><div>Intensive care unit in Brazil.</div></div><div><h3>Patients</h3><div>Tracheostomized adults who were invasively ventilated for more than 14 days and who were weaned from MV.</div></div><div><h3>Interventions</h3><div>Patients were randomized into two groups: intervention group (IG) or a control group (CG). During weaning with a tracheostomy collar, the IG received two daily sessions of MI-E, each with 5 cycles (insufflation and exsufflation pressures of 45 cm H<sub>2</sub>O). The CG received conventional chest physiotherapy.</div></div><div><h3>Main variables of interest</h3><div>The primary outcomes were the feasibility of adding MI-E to the weaning protocol and the rate of successful weaning.</div></div><div><h3>Results</h3><div>A total of 47 patients were randomized, with 25 in the IG and 22 in the CG. All patients randomized to the MI-E group received the proposed protocol, completing all the scheduled MI-E sessions. Adverse events occurred in 14% of the MI-E sessions, but they did not lead to treatment interruption. Weaning success was observed in 76% of IG patients and 73% of CG patients (relative risk, 1.05; 95% CI, 0.75–1.46). No significant differences were observed between the IG and CG regarding ICU mortality (16% and 18%, respectively, p = 0.99) or hospital mortality (40% and 41%, respectively, p = 0.99).</div></div><div><h3>Conclusions</h3><div>The addition of MI-E to the standard weaning protocol is feasible, but not result in a greater rate of successful weaning in tracheostomized patients.</div></div><div><h3>Clinical trial registration number</h3><div>U1111-1302-9035.</div></div>","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"49 6","pages":"Article 502125"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jorge Luis Vélez-Páez , Christian Castro-Bustamante , Manuel Luis Avellanas-Chavala
{"title":"Gasometría y altitud: investigación de los rangos de normalidad en Quito, Ecuador (2.850 m sobre el nivel del mar)","authors":"Jorge Luis Vélez-Páez , Christian Castro-Bustamante , Manuel Luis Avellanas-Chavala","doi":"10.1016/j.medin.2025.502140","DOIUrl":"10.1016/j.medin.2025.502140","url":null,"abstract":"","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"49 6","pages":"Article 502140"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Judit Gutiérrez-Gutiérrez , Jesús Abelardo Barea-Mendoza , Carlos García-Fuentes , Juan Antonio Llompart-Pou , Begoña Guardiola-Grau , Mikel Durán-Suquía , María Ángeles Ballesteros-Sanz , Javier González-Robledo , Lluís Serviá-Goixart , Cristina Méndez-Benegassi Cid , Jose Maria Toboso Casado , Mario Chico-Fernández , En representación del grupo de trabajo de Neurointensivismo y Trauma de la SEMICYUC
{"title":"Traumatismo penetrante en España: análisis del registro español de trauma en la UCI (RETRAUCI)","authors":"Judit Gutiérrez-Gutiérrez , Jesús Abelardo Barea-Mendoza , Carlos García-Fuentes , Juan Antonio Llompart-Pou , Begoña Guardiola-Grau , Mikel Durán-Suquía , María Ángeles Ballesteros-Sanz , Javier González-Robledo , Lluís Serviá-Goixart , Cristina Méndez-Benegassi Cid , Jose Maria Toboso Casado , Mario Chico-Fernández , En representación del grupo de trabajo de Neurointensivismo y Trauma de la SEMICYUC","doi":"10.1016/j.medin.2025.502165","DOIUrl":"10.1016/j.medin.2025.502165","url":null,"abstract":"<div><h3>Objective</h3><div>To describe the epidemiology of penetrating trauma, mortality associated factors and its management in Spanish intensive care units.</div></div><div><h3>Design</h3><div>Multicenter, prospective registry. A comparison is established between two cohorts defined by the type of trauma (blunt and penetrating).</div></div><div><h3>Patients</h3><div>Patients with traumatic injury admitted to the participating ICUs from June 2015 to June 2022.</div></div><div><h3>Interventions</h3><div>None.</div><div>Main variable of interest Epidemiology, injury pattern, prehospital and hospital care, resource utilization, and clinical outcomes.</div></div><div><h3>Results</h3><div>Twelve thousand eight hundred six patients were eligible, of whom 821 (6.4%) suffered penetrating trauma; 418 patients (50.9%) from stab wounds, 93 (11.3%) from gunshot wounds, and 310 (37.8%) from other objects. The most common intent was assault (47.7%). The mean ISS was 15.2<!--> <!-->±<!--> <!-->10.6 in penetrating trauma and 19.8<!--> <!-->±<!--> <!-->11.9 in blunt trauma (<em>P</em><.001). ICU mortality was 7.8% compared to 11.7% in blunt trauma, with deaths more frequently occurring within the first 24<!--> <!-->hours (64 vs. 39%). Factors associated with mortality included female sex, prior use of antithrombotic agents, older age, higher NISS score, and the presence of cranial trauma or shock.</div></div><div><h3>Conclusions</h3><div>Penetrating trauma is an emergent pathology in our context with high complexity, highlighting the need for focused study and documentation, protocol development, and resource optimization to provide quality care.</div></div>","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"49 6","pages":"Article 502165"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hala El Haddad, Isabel Espinosa Rueda, Nora Palomo-López
{"title":"Síndrome aórtico agudo y shock cardiogénico, más allá del diagnóstico radiológico","authors":"Hala El Haddad, Isabel Espinosa Rueda, Nora Palomo-López","doi":"10.1016/j.medin.2024.502124","DOIUrl":"10.1016/j.medin.2024.502124","url":null,"abstract":"","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"49 6","pages":"Article 502124"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mejoría de la hipoperfusión cerebral mediante bloqueo del ganglio estrellado en el vasoespasmo refractario","authors":"Luis Patricio Maskin, Federico Rodríguez Lucci","doi":"10.1016/j.medin.2024.502121","DOIUrl":"10.1016/j.medin.2024.502121","url":null,"abstract":"","PeriodicalId":49268,"journal":{"name":"Medicina Intensiva","volume":"49 6","pages":"Article 502121"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}