Current Problems in Pediatric and Adolescent Health Care最新文献

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Competency-based medical education (CBME) in graduate medical education: Perspectives from learners, faculty, and program leaders 医学研究生教育中的 CBME:学员、教师和项目负责人的观点。
IF 3 4区 医学
Current Problems in Pediatric and Adolescent Health Care Pub Date : 2024-08-30 DOI: 10.1016/j.cppeds.2024.101677
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引用次数: 0
Cerebral palsy in children: A clinical practice review. 儿童脑瘫:临床实践回顾。
IF 3 4区 医学
Current Problems in Pediatric and Adolescent Health Care Pub Date : 2024-08-20 DOI: 10.1016/j.cppeds.2024.101673
Dilip R Patel, Karen M Bovid, Rebecca Rausch, Berrin Ergun-Longmire, Mark Goetting, Joav Merrick
{"title":"Cerebral palsy in children: A clinical practice review.","authors":"Dilip R Patel, Karen M Bovid, Rebecca Rausch, Berrin Ergun-Longmire, Mark Goetting, Joav Merrick","doi":"10.1016/j.cppeds.2024.101673","DOIUrl":"https://doi.org/10.1016/j.cppeds.2024.101673","url":null,"abstract":"<p><p>Cerebral palsy is a disorder characterized by abnormal tone, posture, and movement. In clinical practice, it is often useful to approach cerebral palsy based on the predominant motor system findings - spastic hemiplegia, spastic diplegia, spastic quadriplegia, extrapyramidal or dyskinetic, and ataxic. The prevalence of cerebral palsy is between 1.5 and 3 per 1,000 live births with higher percentage of cases in low to middle income countries and geographic regions. Pre-term birth and low birthweight are recognized as the most frequent risk factors for cerebral palsy; other risk factors include hypoxic-ischemic encephalopathy, maternal infections, and multiple gestation. In most cases of cerebral palsy, the initial injury to the brain occurs during early fetal brain development. Intracerebral hemorrhage and periventricular leukomalacia are the main pathologic findings found in preterm infants who develop spastic cerebral palsy. The diagnosis of cerebral palsy is primarily based on clinical findings. Early recognition of infants at risk for cerebral palsy as well as those with cerebral palsy is possible based on a combination of clinical history, use of standardized neuromotor assessment and findings on magnetic resonance imaging; however, in clinical practice, cerebral palsy is more reliably diagnosed by 2 years of age. Magnetic resonance imaging scan is indicated to delineate the extent of brain lesions and to identify congenital brain malformations. Genetic testing and tests for inborn errors of metabolism are indicated to identify specific disorders, especially treatable disorders. Because cerebral palsy is associated with multiple associated and secondary medical conditions, its management requires a sustained and consistent collaboration among multiple disciplines and specialties. With appropriate support, most children with cerebral palsy grow up to be adults with good functional abilities.</p>","PeriodicalId":49086,"journal":{"name":"Current Problems in Pediatric and Adolescent Health Care","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142019300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Competency-based medical education: Connecting training outcomes to patient care 基于能力的医学教育:将培训成果与病人护理联系起来。
IF 3 4区 医学
Current Problems in Pediatric and Adolescent Health Care Pub Date : 2024-08-14 DOI: 10.1016/j.cppeds.2024.101675
{"title":"Competency-based medical education: Connecting training outcomes to patient care","authors":"","doi":"10.1016/j.cppeds.2024.101675","DOIUrl":"10.1016/j.cppeds.2024.101675","url":null,"abstract":"<div><p>Competency-based medical education (CBME) is a patient-centered and learner-focused approach to education where curricula are delivered in a manner tailored to the individuals’ learning needs, and assessment focuses on ensuring trainees achieve requisite and clearly specified learning outcomes. Despite calls to focus assessment on what matters for patients. In this article, the authors explore one aspect of this next era: the use of electronic health record clinical performance indicators, such as Resident-Sensitive Quality Measures (RSQMs) and TRainee Attributable and Automatable Care Evaluations in Real-time (TRACERs), for learner assessment. They elaborate on both the promise and the potential limitations of using such measures in a program of learner assessment.</p></div>","PeriodicalId":49086,"journal":{"name":"Current Problems in Pediatric and Adolescent Health Care","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141983622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Foreword: Preparing future pediatricians and pediatric subspecialists: Competency-based medical education – Part 2 前言:培养未来的儿科医生和儿科亚专科医生:基于能力的医学教育--第二部分。
IF 3 4区 医学
Current Problems in Pediatric and Adolescent Health Care Pub Date : 2024-08-13 DOI: 10.1016/j.cppeds.2024.101676
{"title":"Foreword: Preparing future pediatricians and pediatric subspecialists: Competency-based medical education – Part 2","authors":"","doi":"10.1016/j.cppeds.2024.101676","DOIUrl":"10.1016/j.cppeds.2024.101676","url":null,"abstract":"","PeriodicalId":49086,"journal":{"name":"Current Problems in Pediatric and Adolescent Health Care","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141983623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accelerating therapeutic development and clinical trial readiness for STXBP1 and SYNGAP1 disorders 加快 STXBP1 和 SYNGAP1 疾病的治疗开发和临床试验准备。
IF 3 4区 医学
Current Problems in Pediatric and Adolescent Health Care Pub Date : 2024-08-01 DOI: 10.1016/j.cppeds.2024.101576
{"title":"Accelerating therapeutic development and clinical trial readiness for STXBP1 and SYNGAP1 disorders","authors":"","doi":"10.1016/j.cppeds.2024.101576","DOIUrl":"10.1016/j.cppeds.2024.101576","url":null,"abstract":"<div><p><span>Gene-targeted therapies for genetic neurodevelopmental disorders (NDDs) are becoming a reality. The Center for Epilepsy and Neurodevelopmental Disorders (ENDD) is currently focused on the development of therapeutics for </span><span><span>STXBP1</span></span> and <span><em>SYNGAP1</em></span><span> disorders. Here we review the known clinical features of these disorders, highlight the biological role of STXBP1 and SYNGAP1, and discuss our current understanding of pathogenic mechanisms and therapeutic development. Finally, we provide our perspective as scientists and parents of children with NDDs, and comment on the current challenges for both clinical and basic science endeavors.</span></p></div>","PeriodicalId":49086,"journal":{"name":"Current Problems in Pediatric and Adolescent Health Care","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140111910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic testing for unexplained epilepsy: A review of diagnostic approach, benefits, and referral algorithm 不明原因癫痫的基因检测:诊断方法、益处和转诊算法综述。
IF 3 4区 医学
Current Problems in Pediatric and Adolescent Health Care Pub Date : 2024-08-01 DOI: 10.1016/j.cppeds.2024.101579
{"title":"Genetic testing for unexplained epilepsy: A review of diagnostic approach, benefits, and referral algorithm","authors":"","doi":"10.1016/j.cppeds.2024.101579","DOIUrl":"10.1016/j.cppeds.2024.101579","url":null,"abstract":"<div><p>In the last several decades, advances in genetic testing have transformed the diagnostic and therapeutic approach to pediatric epilepsy<span>. However, the interpretation of these genetic tests often requires expert analysis and counseling. For this reason, as our molecular understanding of the linkages between abnormal cerebral physiology and genetics<span> has grown, so too has the field of clinical epilepsy genetics. Here we explore recent advances in genetic testing, describe the benefits of genetic testing in epilepsy, and provide a practice guideline for testing and referrals to specialized epilepsy genetics centers, highlighting the Epilepsy NeuroGenetics Initiative (ENGIN) Clinic and the Center for Epilepsy and Neurodevelopmental Disorders (ENDD) at the Children's Hospital of Philadelphia as an illustration of such a specialized center.</span></span></p></div>","PeriodicalId":49086,"journal":{"name":"Current Problems in Pediatric and Adolescent Health Care","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140121170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in big data and omics: Paving the way for discovery in childhood epilepsies 大数据和全息技术的进步:为发现儿童癫痫铺平道路。
IF 3 4区 医学
Current Problems in Pediatric and Adolescent Health Care Pub Date : 2024-08-01 DOI: 10.1016/j.cppeds.2024.101634
{"title":"Advances in big data and omics: Paving the way for discovery in childhood epilepsies","authors":"","doi":"10.1016/j.cppeds.2024.101634","DOIUrl":"10.1016/j.cppeds.2024.101634","url":null,"abstract":"<div><p>The insights gained from big data and omics approaches have transformed the field of childhood genetic<span> epilepsy. With an increasing number of individuals receiving genetic testing for seizures, we are provided with an opportunity to identify clinically relevant subgroups and extract meaningful observations from this large-scale clinical data. However, the volume of data from electronic medical records and omics (e.g., genomics, transcriptomics) is so vast that standardized methods, such as the Human Phenotype Ontology, are necessary for reliable and comprehensive characterization. Here, we explore the integration of clinical and omics data, highlighting how these approaches pave the way for discovery in childhood epilepsies.</span></p></div>","PeriodicalId":49086,"journal":{"name":"Current Problems in Pediatric and Adolescent Health Care","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141201004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial Board Page 编辑委员会页面
IF 3 4区 医学
Current Problems in Pediatric and Adolescent Health Care Pub Date : 2024-08-01 DOI: 10.1016/S1538-5442(24)00118-4
{"title":"Editorial Board Page","authors":"","doi":"10.1016/S1538-5442(24)00118-4","DOIUrl":"10.1016/S1538-5442(24)00118-4","url":null,"abstract":"","PeriodicalId":49086,"journal":{"name":"Current Problems in Pediatric and Adolescent Health Care","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1538544224001184/pdfft?md5=cde5f5d80d551303f389b9b89afd031d&pid=1-s2.0-S1538544224001184-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141962312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FOREWORD: Innovation in Managing Childhood Epilepsy-Part-2 前言:管理儿童癫痫的创新--第二部分。
IF 3 4区 医学
Current Problems in Pediatric and Adolescent Health Care Pub Date : 2024-08-01 DOI: 10.1016/j.cppeds.2024.101654
{"title":"FOREWORD: Innovation in Managing Childhood Epilepsy-Part-2","authors":"","doi":"10.1016/j.cppeds.2024.101654","DOIUrl":"10.1016/j.cppeds.2024.101654","url":null,"abstract":"","PeriodicalId":49086,"journal":{"name":"Current Problems in Pediatric and Adolescent Health Care","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141460247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of psychology and neuropsychology in pediatric epilepsy surgery evaluation 心理学和神经心理学在小儿癫痫手术评估中的作用。
IF 3 4区 医学
Current Problems in Pediatric and Adolescent Health Care Pub Date : 2024-08-01 DOI: 10.1016/j.cppeds.2024.101592
{"title":"The role of psychology and neuropsychology in pediatric epilepsy surgery evaluation","authors":"","doi":"10.1016/j.cppeds.2024.101592","DOIUrl":"10.1016/j.cppeds.2024.101592","url":null,"abstract":"<div><p><span><span>Epilepsy is one of the most common neurological problems affecting 470,000 children in the United States. While most youth will achieve seizure freedom using medication, up to a third will continue to have seizures and are therefore considered to have drug-resistant epilepsy (DRE). Children and adolescents with epilepsy are at higher risk of behavioral, cognitive, and emotional disorders. Youth with DRE are at even greater risk of behavioral and emotional problems impacting </span>quality of life and may need to pursue surgical interventions, including resective surgery or device implantation. Due to advances in the evaluation of candidates and surgical options, </span>epilepsy surgery is more effective and has become second-line treatment for youth with DRE. This paper highlights the importance of exploring, assessing, and treating psychological and neuropsychological factors throughout the three phases of the epilepsy surgery process and ways pediatricians can support youth and families.</p></div>","PeriodicalId":49086,"journal":{"name":"Current Problems in Pediatric and Adolescent Health Care","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140330254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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