Giornale Italiano Di Dermatologia E Venereologia最新文献

{"title":"Dermatoscopy of melanoma according to type, anatomic site and stage: a 2020 update.","authors":"A. Lallas, E. Paschou, S. Manoli, C. Papageorgiou, I. Spyridis, K. Liopyris, Mattheos Bobos, Andreas Moutsoudis, E. Lazaridou, Z. Apalla","doi":"10.23736/S0392-0488.20.06784-X","DOIUrl":"https://doi.org/10.23736/S0392-0488.20.06784-X","url":null,"abstract":"The indisputable contribution of dermatoscopy in early diagnosis of melanoma is widely recognized. In the last quinquennium, new data concerning specific melanoma subtypes have come to light. The dermatoscopic morphology of superficial spreading melanoma (SSM) has been extensively investigated in the literature. Atypical network, irregular dots, irregular globules, irregular streaks and irregular blotch correspond to histopathologic alterations at the level of the junction, blue-white veil and atypical vessels suggest intradermal growth, whereas regression structures, negative network and white shiny streaks might reflect junctional or dermal alterations. The list of melanoma specific criteria has been recently updated to include features that typify early melanoma, such as irregular hyperpigmented areas and prominent skin markings and features seen in melanoma on sun damaged skin such as angulated lines. Nodular melanoma lacks most of the aforementioned criteria and is typified by the coexistence of blue and black color, atypical vessels and pink color. Lentigo maligna dermatoscopic criteria mainly develop at the outline of the follicular openings. However, at an early stage these features might be very subtle and the diagnosis should be based on the exclusion of benign tumors (inverse approach). Acral lentiginous melanoma is typified by a parallel ridge pattern, but also SSM criteria should be taken into consideration. The diagnosis of subungual melanoma is based on the assessment of the color and characteristics of the pigmented nail band. For the diagnosis of mucosal melanoma, the assessment of colors is more informative than the assessment of structures and the detection of blue, white or gray should raise the suspicion of melanoma. White shiny streaks and regression structures are the most common features of desmoplastic melanoma. The diagnosis of nevoid melanoma might be highly challenging and require information on the lesion's history. Melanoma on small- and medium-sized congenital nevi is typified by an eccentric location of the suspicious area, negative network and gray angulated lines. Recent advances in knowledge on the dermatoscopic characteristics of peculiar subtypes of the tumor significantly enrich the diagnostic armamentarium of clinicians. The challenge of the forthcoming years is to better characterize biologically aggressive melanomas and to optimize the screening strategies so as to identify them.","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":"35 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72501021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erytromelanosis faciei successfully treated with low-dose oral isotretinoin.","authors":"F. Filippi, L. Vollono, B. Piraccini, C. Misciali, F. Tartari, I. Neri","doi":"10.23736/S0392-0488.20.06858-3","DOIUrl":"https://doi.org/10.23736/S0392-0488.20.06858-3","url":null,"abstract":"","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":"48 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87955736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pemphigus: a critical review on clinical subtypes, pathogenesis, diagnostics and established and novel therapeutics.","authors":"R. Eming, C. Zimmer, M. Hertl","doi":"10.23736/S0392-0488.20.06790-5","DOIUrl":"https://doi.org/10.23736/S0392-0488.20.06790-5","url":null,"abstract":"","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":"243 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77174347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Thick melanoma in Tuscany.","authors":"Alessandra Chiarugi,&nbsp;Paolo Nardini,&nbsp;Lorenzo Borgognoni,&nbsp;Paola Brandani,&nbsp;Gianni Gerlini,&nbsp;Pietro Rubegni,&nbsp;Arianna Lamberti,&nbsp;Camilla Salvini,&nbsp;Giovanni Lo Scocco,&nbsp;Roberto Cecchi,&nbsp;Riccardo Sirna,&nbsp;Stefano Lorenzi,&nbsp;Riccardo Gattai,&nbsp;Silvio Battistini,&nbsp;Emanuele Crocetti","doi":"10.23736/S0392-0488.21.06995-9","DOIUrl":"https://doi.org/10.23736/S0392-0488.21.06995-9","url":null,"abstract":"<p><p>This corrects the article DOI: 10.23736/S0392-0488.17.05584-5.</p>","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":"155 6","pages":"807"},"PeriodicalIF":2.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25423403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psoriatic arthritis onset in psoriatic patients receiving UV phototherapy in Italy.","authors":"Anna Balato,&nbsp;Giuseppina Caiazzo,&nbsp;Nicola Balato,&nbsp;Maddalena Napolitano","doi":"10.23736/S0392-0488.18.06117-5","DOIUrl":"https://doi.org/10.23736/S0392-0488.18.06117-5","url":null,"abstract":"<p><strong>Background: </strong>Psoriasis is a chronic, recurrent, and immune-mediated inflammatory disease that affects 2-3% of the world population. A substantial proportion of patients with psoriasis, approximately 40%, develop a form of inflammatory arthritis known as psoriatic arthritis (PsA), the arthritis follows the development of psoriasis, and it will develop simultaneously or possibly before the appearance of skin lesions. The presence of PsA indicates a need for more active intervention rather than purely topical therapies or UV-based therapies. The aim of this multicenter, retrospective, epidemiological study was to estimate the incidence of PsA in psoriatic patients receiving UV treatment as monotherapy.</p><p><strong>Methods: </strong>A retrospective epidemiological study was performed in 8 dermatological reference center, located throughout Italy (2 from Northern, 3 from Center, 3 from Southern); a period of 1 year was considered. Data from the overall study population including 326 patients with a diagnosis of psoriasis were analyzed. Furthermore, data coming from follow-up visits, including screening for PsA onset through specific questionnaires were analyzed.</p><p><strong>Results: </strong>PsA screening was positive in 27 patients (8.3%), whereas PsA diagnosis was confirmed by a rheumatologist in only 22/27 (81.5%) being therefore found in 22/326 (6.7%). Patients diagnosed with PsA had a statistically significantly higher abdominal circumference (96±15.3 vs. 88.9±18.3, P=0.048) and more commonly presented a positive past medical history for phototherapy (90.9% vs. 57.6% P=0.004).</p><p><strong>Conclusions: </strong>Our study showed that phototherapy is not able to prevent or slow down the risk of PsA development in psoriatic patients. PsA screening should be always carried out in those patients even if asymptomatic, especially in obese subjects which are at great risk to develop PsA due to their increased systemic inflammatory state.</p>","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":"155 6","pages":"733-738"},"PeriodicalIF":2.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36519115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric dermatologic surgery: our experience.","authors":"Antonella Fabiano,&nbsp;Ruggero Moro,&nbsp;Cristina Zane,&nbsp;Simone Caravello,&nbsp;Marta Fusano,&nbsp;Piergiacomo Calzavara-Pinton,&nbsp;Giulio Gualdi","doi":"10.23736/S0392-0488.18.06140-0","DOIUrl":"https://doi.org/10.23736/S0392-0488.18.06140-0","url":null,"abstract":"<p><strong>Background: </strong>Surgical treatment for pediatric skin disorders is used for diagnostic and therapeutic reasons. We underline these procedures are usually easy and uncomplicated without the need for general anesthesia. Objective of this study was to share our experience in the field of pediatric dermatologic surgery.</p><p><strong>Methods: </strong>We retrospectively analysed records of all pediatric patients receiving surgical therapy at the Dermatology Department of Spedali Civili of Brescia. Demographic data and treatments characteristics were recorded and analyzed.</p><p><strong>Results: </strong>During the study period of one year, 670 surgical treatments concerning pediatric patients were collected. Number of procedures progressively grows with increasing age. All treatments were performed under local anesthesia except for a dermatofibrosarcoma protuberans for which general anesthesia was needed.</p><p><strong>Conclusions: </strong>Our data show that cryosurgery, electrodessication and excisional surgery constitute with equal proportion almost the whole of surgical procedures in dermatologic pediatric patients. Dermatologist's habit to perform surgery in local anesthesia avoids the risk of overtreatments, limits discomfort, anxiety, and pain perception linked to procedures performed.</p>","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":"155 6","pages":"775-779"},"PeriodicalIF":2.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36519120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two rare diseases in the same patient: neurofibromatosis type 1 and Madelung's disease.","authors":"Emanuele Miraglia,&nbsp;Pasquale Fino,&nbsp;Stefano Calvieri,&nbsp;Sandra Giustini","doi":"10.23736/S0392-0488.18.06166-7","DOIUrl":"https://doi.org/10.23736/S0392-0488.18.06166-7","url":null,"abstract":"","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":"155 6","pages":"798-799"},"PeriodicalIF":2.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36608087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimation of direct costs of melanoma in the Veneto Region: a budget assessment and cost-consequence analysis.","authors":"Alessandra Buja,&nbsp;Gino Sartor,&nbsp;Manuela Scioni,&nbsp;Giovanni Girardi,&nbsp;Antonella Vecchiato,&nbsp;Mario Bolzan,&nbsp;Vincenzo Rebba,&nbsp;Vanna Chiarion Sileni,&nbsp;Angelo Claudio Palozzo,&nbsp;Maria Montesco,&nbsp;Paolo Del Fiore,&nbsp;Vincenzo Baldo,&nbsp;Carlo Riccardo Rossi","doi":"10.23736/S0392-0488.18.06106-0","DOIUrl":"https://doi.org/10.23736/S0392-0488.18.06106-0","url":null,"abstract":"<p><strong>Background: </strong>While many evidence-based pathways have been introduced to drive quality improvements in cancer care, most of these do not include evidence about their affordability. The main aim of this study was to provide an estimation of the overall budget to cover all the needs of melanoma patients in Veneto Region, managed according to the clinical pathway defined by the Rete Oncologica Veneta. A second objective is to conduct a cost-consequence analysis, comparing two different treatments.</p><p><strong>Methods: </strong>A very detailed whole-disease model was developed describing the patient's pathway from diagnosis through the first year of follow-up. Each procedure involved in the model was associated with a likelihood measure and a cost. The model can be used to estimate the expected direct costs associated with melanoma.</p><p><strong>Results: </strong>We can observe that 0 and I stage, despite accounting for a huge percentage of new melanoma cases are characterized by a small percentage of the total costs. Stage III can be considered as the most expensive stage accounting for 54% of the total costs with a 12% of patients. Finally, the stage IV patients, although very few accounts for almost the 7% of the total costs. Regarding the cost-consequence analysis, it was estimated that the therapies introduced in 2016 led to an approximately 14% increase in the total costs.</p><p><strong>Conclusions: </strong>Modeling a clinical pathway with a high level of detail enables to identify the main sources of spending. The consequent analysis can thus help policymakers to plan the future resources allocation.</p>","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":"155 6","pages":"764-771"},"PeriodicalIF":2.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36665411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AcuPru, a pilot study on acupuncture as a viable therapeutic approach to chronic itch: development of two experimental protocols among dermatological adult patients.","authors":"Lidia Sacchelli,&nbsp;Gabriele Bovina,&nbsp;Carlo M Giovanardi,&nbsp;Umberto Mazzanti,&nbsp;Francesca Ferrara,&nbsp;Annalisa Patrizi,&nbsp;Federico Bardazzi","doi":"10.23736/S0392-0488.18.06158-8","DOIUrl":"https://doi.org/10.23736/S0392-0488.18.06158-8","url":null,"abstract":"","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":"155 6","pages":"794-796"},"PeriodicalIF":2.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37630007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Actinic keratoses: when and how to treat a single lesion.","authors":"Anna Carbone,&nbsp;Vitaliano Silipo,&nbsp;Laura Eibenschutz,&nbsp;Paolo Piemonte,&nbsp;Angela Ferrari,&nbsp;Pierluigi Buccini,&nbsp;Alessandra Iorio,&nbsp;Pasquale Frascione","doi":"10.23736/S0392-0488.21.06996-0","DOIUrl":"https://doi.org/10.23736/S0392-0488.21.06996-0","url":null,"abstract":"<p><p>This corrects the article DOI: 10.23736/S0392-0488.18.06082-0.</p>","PeriodicalId":49071,"journal":{"name":"Giornale Italiano Di Dermatologia E Venereologia","volume":"155 6","pages":"808"},"PeriodicalIF":2.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25423868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}