Fernando Henrique Carlos de Souza , Daniel Brito de Araújo , Clovis Artur Silva , Renata Miossi , Carmita Helena Najjar Abdo , Eloisa Bonfá , Samuel Katsuyuki Shinjo
{"title":"Análise da função sexual de pacientes com dermatomiosite e polimiosite através de questionários autoaplicados: um estudo transversal","authors":"Fernando Henrique Carlos de Souza , Daniel Brito de Araújo , Clovis Artur Silva , Renata Miossi , Carmita Helena Najjar Abdo , Eloisa Bonfá , Samuel Katsuyuki Shinjo","doi":"10.1016/j.rbr.2016.08.006","DOIUrl":"https://doi.org/10.1016/j.rbr.2016.08.006","url":null,"abstract":"<div><h3>Introduction</h3><p>To date, there are no descriptions in the literature on gynecologic and sexual function evaluation in female patients with dermatomyositis (DM) and polymyositis (PM).</p></div><div><h3>Objective</h3><p>To assess sexual function in female patients with DM/PM.</p></div><div><h3>Patients and methods</h3><p>This is a monocentric, cross‐sectional study in which 23 patients (16 DM and 7 PM), with ages between 18 and 40 years, were compared to 23 healthy women of the same age group. Characteristics on sexual function were obtained by applying the questionnaires Female Sexual Quotient (FSQ) and Female Sexual Function Index (FSFI) validated for the Brazilian Portuguese language.</p></div><div><h3>Results</h3><p>The mean age of patients was comparable to controls (32.7<!--> <!-->±<!--> <!-->5.3 vs. 31.7<!--> <!-->±<!--> <!-->6.7 years), as well as the distribution of ethnicity and socioeconomic class. As for gynecological characteristics, patients and healthy controls did not differ with respect to age at menarche and percentages of dysmenorrhea, menorrhagia, premenstrual syndrome, pain at mid‐cycle, mucocervical secretion, and vaginal discharge. The FSQ score, as well as all domains of the FSFI questionnaire (desire, arousal, lubrication, orgasm and satisfaction), were significantly decreased in patients versus controls, with 60.9% of patients showing some degree of sexual dysfunction.</p></div><div><h3>Conclusions</h3><p>This was the first study to identify sexual dysfunction in patients with DM/PM. Therefore, a multidisciplinary approach is essential for patients with idiopathic inflammatory myopathies, in order to provide prevention and care for their sexual life, providing a better quality of life, both for patients and their partners.</p></div>","PeriodicalId":48991,"journal":{"name":"Revista Brasileira De Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbr.2016.08.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91676817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saime Ay , Hatice Ecem Konak , Deniz Evcik , Sibel Kibar
{"title":"Efetividade do kinesio taping na dor e incapacidade na síndrome dolorosa miofascial cervical","authors":"Saime Ay , Hatice Ecem Konak , Deniz Evcik , Sibel Kibar","doi":"10.1016/j.rbr.2015.12.004","DOIUrl":"10.1016/j.rbr.2015.12.004","url":null,"abstract":"<div><h3>Objective</h3><p>The aim of this study was to investigate the effectiveness of Kinesio Taping and sham Kinesio Taping on pain, pressure pain treshold, cervical range of motion, and disability in cervical myofascial pain syndrome patients (MPS).</p></div><div><h3>Methods</h3><p>This study was designed as a randomized, double‐blind placebo controlled study. Sixty one patients with MPS were randomly assigned into two groups. Group 1 (n<!--> <!-->=<!--> <!-->31) were treated with Kinesio Taping and group 2 (n<!--> <!-->=<!--> <!-->30) were treated sham taping five times by intervals of 3 days for 15 days. Additionally, all patients were given neck exercise program. Patients were evaluated according to pain, pressure pain treshold, cervical range of motion and disability. Pain was assessed by using Visual Analog Scale, pressure pain treshold was measured by using an algometer, and active cervical range of motion was measured by using goniometry. Disability was assessed with the neck pain disability index disability. Measurements were taken before and after the treatment.</p></div><div><h3>Results</h3><p>At the end of the therapy, there were statistically significant improvements on pain, pressure pain treshold, cervical range of motion, and disability (p<!--> <!--><<!--> <!-->0.05) in both groups. Also there was a statistical difference between the groups regarding pain, pressure pain treshold, cervical flexion‐extension (p<!--> <!--><<!--> <!-->0.05); except cervical rotation, cervical lateral flexion and disability(p<!--> <!-->><!--> <!-->0.05).</p></div><div><h3>Conclusion</h3><p>This study shows that Kinesio Taping leads to improvements on pain, pressure pain treshold and cervical range of motion, but not disability in short time. Therefore, Kinesio Taping can be used as an alternative therapy method in the treatment of patients with MPS.</p></div>","PeriodicalId":48991,"journal":{"name":"Revista Brasileira De Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbr.2015.12.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46587172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alex Magno Coelho Horimoto, E. N. Matos, Márcio da Silva Costa, F. Takahashi, M. C. Rezende, Letícia Barrios Kanomata, Elisangela Possebon Pradebon Locatelli, L. Finotti, F. Maegawa, Rosa Maria Ribeiro Rondon, N. Machado, Flávia Midori Arakaki Ayres Tavares do Couto, Túlia Peixoto Alves de Figueiredo, Raphael Antonio Ovidio, I. Costa
{"title":"Incidence and prevalence of systemic sclerosis in Campo Grande, State of Mato Grosso do Sul, Brazil.","authors":"Alex Magno Coelho Horimoto, E. N. Matos, Márcio da Silva Costa, F. Takahashi, M. C. Rezende, Letícia Barrios Kanomata, Elisangela Possebon Pradebon Locatelli, L. Finotti, F. Maegawa, Rosa Maria Ribeiro Rondon, N. Machado, Flávia Midori Arakaki Ayres Tavares do Couto, Túlia Peixoto Alves de Figueiredo, Raphael Antonio Ovidio, I. Costa","doi":"10.1016/j.rbr.2016.05.008","DOIUrl":"https://doi.org/10.1016/j.rbr.2016.05.008","url":null,"abstract":"","PeriodicalId":48991,"journal":{"name":"Revista Brasileira De Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbr.2016.05.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44359008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Felipe Garza‐García , Guillermo Delgado‐García , Mario Garza‐Elizondo , Luis Ángel Ceceñas‐Falcón , Dionicio Galarza‐Delgado , Janett Riega‐Torres
{"title":"A β2‐microglobulina salivar se correlaciona positivamente com o ESSPRI em pacientes com síndrome de Sjögren primária","authors":"Felipe Garza‐García , Guillermo Delgado‐García , Mario Garza‐Elizondo , Luis Ángel Ceceñas‐Falcón , Dionicio Galarza‐Delgado , Janett Riega‐Torres","doi":"10.1016/j.rbr.2016.09.006","DOIUrl":"10.1016/j.rbr.2016.09.006","url":null,"abstract":"","PeriodicalId":48991,"journal":{"name":"Revista Brasileira De Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbr.2016.09.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"55036295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Javier Fernández‐Torres , Gabriela Angélica Martínez‐Nava , María Concepción Gutiérrez‐Ruíz , Luis Enrique Gomez‐Quiroz , Marwin Gutiérrez
{"title":"Papel da via de sinalização do HIF‐1α na osteoartrite: revisão sistemática","authors":"Javier Fernández‐Torres , Gabriela Angélica Martínez‐Nava , María Concepción Gutiérrez‐Ruíz , Luis Enrique Gomez‐Quiroz , Marwin Gutiérrez","doi":"10.1016/j.rbr.2016.04.006","DOIUrl":"10.1016/j.rbr.2016.04.006","url":null,"abstract":"<div><p>Osteoarthritis (OA) is the most common form of arthritis and is frequently diagnosed and managed in primary care; it is characterized by loss of articular hyaline cartilage, which is a unique connective tissue that physiologically lacks blood vessels. Articular cartilage survives in a microenvironment devoid of oxygen, which is regulated by hypoxia inducible factor (HIF‐1α). HIF‐1α is considered the main transcriptional regulator of cellular and developmental response to hypoxia. To date, the relevance of HIF‐1α in the assessment of cartilage has increased since its participation is essential in the homeostasis of this tissue. Taking into account the new emerging insights of HIF‐1α in the scientific literature in the last years, we focused the present review on the potential role of HIF‐1α signaling pathway in OA development, especially in how some genetic factors may influence the maintenance or breakdown of articular cartilage.</p></div>","PeriodicalId":48991,"journal":{"name":"Revista Brasileira De Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbr.2016.04.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48583724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sherif Taha , Sherif Mohammed Gamal , Mohamed Nabil , Nahla Naeem , Dalia Labib , Ibrahim Siam , Tamer Atef Gheita
{"title":"Polimorfismo genético do fator de crescimento vascular endotelial G1612A (rs10434) e manifestações neuropsiquiátricas em pacientes com lúpus eritematoso sistêmico","authors":"Sherif Taha , Sherif Mohammed Gamal , Mohamed Nabil , Nahla Naeem , Dalia Labib , Ibrahim Siam , Tamer Atef Gheita","doi":"10.1016/j.rbr.2016.08.005","DOIUrl":"10.1016/j.rbr.2016.08.005","url":null,"abstract":"<div><h3>Aim</h3><p>To investigate the relation between vascular endothelial growth factor (VEGF) gene polymorphism in systemic lupus erythematosus (SLE) patients and lupus related neuropsychiatric manifestations.</p></div><div><h3>Patients and methods</h3><p>Sixty adult SLE patients recruited from the Rheumatology and Neurology departments of Cairo University hospitals were classified into two groups; Group A: 30 patients with neuropsychiatric manifestations (NPSLE) and Group B: 30 patients without. For both groups the SNP G1612A (rs10434) of the VEGF gene was genotyped by real time polymerase chain reaction (RT‐PCR).</p></div><div><h3>Results</h3><p>Statistically significant difference was found in genotype and allele frequencies between both groups (AA [70% vs 13.3%, p<!--> <!--><<!--> <!-->0.001] and GG [10% vs 66.7%, p<!--> <!--><<!--> <!-->0.001]).</p></div><div><h3>Conclusion</h3><p>Polymorphism in the gene coding for VEGF may be associated with increased incidence of neuropsychiatric lupus in SLE patients.</p></div>","PeriodicalId":48991,"journal":{"name":"Revista Brasileira De Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbr.2016.08.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46602875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rosa Weiss Telles, Luciana Costa‐Silva, Luciana A.C. Machado, Rodrigo Citton Padilha dos Reis, Sandhi Maria Barreto
{"title":"A radiografia do joelho em flexão fixa utilizando um novo posicionador produziu medidas da largura do espaço articular com alta repetibilidade: estudo ELSA‐Brasil Musculoesquelético (ELSA‐Brasil ME)","authors":"Rosa Weiss Telles, Luciana Costa‐Silva, Luciana A.C. Machado, Rodrigo Citton Padilha dos Reis, Sandhi Maria Barreto","doi":"10.1016/j.rbr.2016.10.003","DOIUrl":"10.1016/j.rbr.2016.10.003","url":null,"abstract":"<div><h3>Objective</h3><p>To describe the performance of a non‐fluoroscopic fixed‐flexion PA radiographic protocol with a new positioning device, developed for the assessment of knee osteoarthritis (OA) in ELSA‐Brasil MSK.</p></div><div><h3>Material and methods</h3><p>A test‐retest design including 19 adults (38 knee images) was conducted. Feasibility of the radiographic protocol was assessed by image quality parameters and presence of radioanatomic alignment according to intermargin distance (IMD) values. Repeatability was assessed for IMD and joint space width (JSW) measured at three different locations.</p></div><div><h3>Results</h3><p>Approximately 90% of knee images presented excellent quality. Frequencies of nearly perfect radioanatomic alignment (IMD ≤1<!--> <!-->mm) ranged from 29% to 50%, and satisfactory alignment was found in up to 71% and 76% of the images (IMD ≤1.5<!--> <!-->mm and ≤1.7<!--> <!-->mm, respectively). Repeatability analyses yielded the following results: IMD [SD of mean difference<!--> <!-->=<!--> <!-->1.08; coefficient of variation (%CV)<!--> <!-->=<!--> <!-->54.68%; intraclass correlation coefficient (ICC) (95%CI)<!--> <!-->=<!--> <!-->0.59 (0.34‐0.77)]; JSW [SD of mean difference<!--> <!-->=<!--> <!-->0.34 ‐ 0.61; %CV<!--> <!-->=<!--> <!-->4.48% ‐ 9.80%; ICC (95%CI)<!--> <!-->=<!--> <!-->0.74 (0.55‐0.85) ‐ 0.94 (0.87‐0.97)]. Adequately reproducible measurements of IMD and JSW were found in 68% and 87% of the images, respectively.</p></div><div><h3>Conclusions</h3><p>Despite the difficulty in achieving consistent radioanatomic alignment between subsequent radiographs in terms of IMD, the protocol produced highly repeatable JSW measurements when these were taken at midpoint and 10<!--> <!-->mm from the medial extremity of the medial tibial plateu. Therefore, measurements of JSW at these locations can be considered adequate for the assessment of knee OA in ELSA‐Brasil MSK.</p></div>","PeriodicalId":48991,"journal":{"name":"Revista Brasileira De Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbr.2016.10.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46643832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vanessa Patricia L. Pereira , Teresa Cristina Martins Vicente Robazzi
{"title":"Uso de imunobiológicos e desenvolvimento de doenças neoplásicas em pacientes com doenças reumáticas juvenis: revisão sistemática","authors":"Vanessa Patricia L. Pereira , Teresa Cristina Martins Vicente Robazzi","doi":"10.1016/j.rbr.2016.09.001","DOIUrl":"10.1016/j.rbr.2016.09.001","url":null,"abstract":"<div><p>Juvenile rheumatic diseases affect the musculoskeletal system and begin before the age of 18. These conditions have varied, identifiable or unknown etiologies, but those of an autoimmune inflammatory nature have been associated with an increased risk of development of cancer, regardless of treatment. This study aims to assess, through a systematic review of the literature according to Prisma (Preferred Reporting Items for Systematic Reviews and Meta‐Analyses) quality criteria, the risk of cancer in patients with juvenile rheumatic disease, and its association with biological agents. The criteria described by the Strengthening the Reporting of Observational Studies in Epidemiology initiative were used in order to assess the methodological quality of those individual items selected in this study. We analyzed nine publications, from a total of 251 papers initially selected. There was an increase in cancer risk in the population with juvenile rheumatic disease <em>versus</em> the general population. Most specified cancers were of a lymphoproliferative nature. Seven studies did not specify the treatment or not defined an association between treatment and cancer risk. Only one study has suggested this association; in it, their authors observed high risk in patients diagnosed in the last 20 years, a period of the advent of new therapies. One study found an increased risk in a population not treated with biological agents, suggesting a disease in its natural course, and not an adverse effect of therapy. Studies have shown an increased risk of malignancy associated with juvenile rheumatic disease, and this may be related to disease activity and not specifically to the treatment with biological agents.</p></div>","PeriodicalId":48991,"journal":{"name":"Revista Brasileira De Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbr.2016.09.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42983324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"O envolvimento do nervo mediano na artrite reumatoide tem sido excessivamente valorizado?","authors":"Rajalingham Sakthiswary , Rajesh Singh","doi":"10.1016/j.rbr.2016.07.002","DOIUrl":"10.1016/j.rbr.2016.07.002","url":null,"abstract":"<div><p>Rheumatoid arthritis (RA) is a well and widely recognised cause of carpal tunnel syndrome (CTS). In the rheumatoid wrist, synovial expansion, joint erosions and ligamentous laxity result in compression of the median nerve due to increased intracarpal pressure. We evaluated the published studies to determine the prevalence of CTS and the characteristics of the median nerve in RA and its association with clinical parameters such as disease activity, disease duration and seropositivity. A total of 13 studies met the eligibility criteria. Pooled data from 8 studies with random selection of RA patients revealed that 86 out of 1561 (5.5%) subjects had CTS. Subclinical CTS, on the other hand, had a pooled prevalence of 14.0% (30/215). The cross sectional area of the median nerve of the RA patients without CTS were similar to the healthy controls. The vast majority of the studies (8/13) disclosed no significant relationship between the median nerve findings and the clinical or laboratory parameters in RA. The link between RA and the median nerve abnormalities has been overemphasized throughout the literature. The prevalence of CTS in RA is similar to the general population without any correlation between the median nerve characteristics and the clinical parameters of RA.</p></div>","PeriodicalId":48991,"journal":{"name":"Revista Brasileira De Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbr.2016.07.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42325617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alex Magno Coelho Horimoto , Erica Naomi Naka Matos , Márcio Reis da Costa , Fernanda Takahashi , Marcelo Cruz Rezende , Letícia Barrios Kanomata , Elisangela Possebon Pradebon Locatelli , Leandro Tavares Finotti , Flávia Kamy Maciel Maegawa , Rosa Maria Ribeiro Rondon , Natália Pereira Machado , Flávia Midori Arakaki Ayres Tavares do Couto , Túlia Peixoto Alves de Figueiredo , Raphael Antonio Ovidio , Izaias Pereira da Costa
{"title":"Incidência e prevalência de esclerose sistêmica em Campo Grande, Estado de Mato Grosso do Sul, Brasil","authors":"Alex Magno Coelho Horimoto , Erica Naomi Naka Matos , Márcio Reis da Costa , Fernanda Takahashi , Marcelo Cruz Rezende , Letícia Barrios Kanomata , Elisangela Possebon Pradebon Locatelli , Leandro Tavares Finotti , Flávia Kamy Maciel Maegawa , Rosa Maria Ribeiro Rondon , Natália Pereira Machado , Flávia Midori Arakaki Ayres Tavares do Couto , Túlia Peixoto Alves de Figueiredo , Raphael Antonio Ovidio , Izaias Pereira da Costa","doi":"10.1016/j.rbr.2016.05.008","DOIUrl":"https://doi.org/10.1016/j.rbr.2016.05.008","url":null,"abstract":"<div><h3>Introduction</h3><p>Systemic sclerosis (SSc) is an autoimmune disease which shows extreme heterogeneity in its clinical presentation and that follows a variable and unpredictable course. Although some discrepancies in the incidence and prevalence rates between geographical regions may reflect methodological differences in the definition and verification of cases, they may also reflect true local differences.</p></div><div><h3>Objectives</h3><p>To determine the prevalence and incidence of SSc in the city of Campo Grande, state capital of Mato Grosso do Sul (MS), Brazil, during the period from January to December 2014.</p></div><div><h3>Methods</h3><p>All health care services of the city of Campo Grande ‐ MS with attending in the specialty of Rheumatology were invited to participate in the study through a standardized form of clinical and socio‐demographic assessment. Physicians of any specialty could report a suspected case of SSc, but necessarily the definitive diagnosis should be established by a rheumatologist, in order to warrant the standardization of diagnostic criteria and exclusion of other diseases resembling SSc. At the end of the study, 15 rheumatologists reported that they attended patients with SSc and sent the completed forms containing epidemiological data of patients.</p></div><div><h3>Results</h3><p>The incidence rate of SSc in Campo Grande for the year 2014 was 11.9 per million inhabitants and the prevalence rate was 105.6 per million inhabitants. SSc patients were mostly women, white, with a mean age of 50.58 years, showing the limited form of the disease with a mean duration of the disease of 8.19 years. Regarding laboratory tests, 94.4% were positive for ANA, 41.6% for ACA and 19.1% for anti‐Scl70; anti‐RNA Polymerase <span>III</span> was performed in 37 patients, with 16.2% positive.</p></div><div><h3>Conclusions</h3><p>The city of Campo Grande, the state capital of MS, presented a lower incidence/prevalence of SSc in comparison with those numbers found in US studies and close to European studies’ data.</p></div>","PeriodicalId":48991,"journal":{"name":"Revista Brasileira De Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbr.2016.05.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91676812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}