Lazernaâ medicina最新文献

{"title":"The efficacy of clinical application of light-oxygen therapy for treating hemangiomas (a clinical case)","authors":"N. V. Drozdova, Yu. V. Alekseev, A. A. Lukovkina","doi":"10.37895/2071-8004-2023-27-2-48-51","DOIUrl":"https://doi.org/10.37895/2071-8004-2023-27-2-48-51","url":null,"abstract":"Purpose. To describe a clinical case of successful application of ligh t-oxygen therapy (LOT) for treating a patient with a cherry angioma. Materials and methods. The publication presents a clinical case of successful application of LOT irradiation in the absorption spectrum of endogenous oxygen with its transfer into singlet state for treating a cherry angioma. Russian-made diode laser “Super Seb” with wavelength close to 1265 nm (manufacturer LLC “New Surgical Technologies”, Moscow), laser power from 0 to 3 Wt was used as a source of laser light. In the described case, irradiation power was 2.4 Wt; power density – 0.76 W/cm 2 ; exposure dose – 365 J/cm 2 ; maximal surface temperature during session – 38 °C. Temperature was measured with a non–contact infrared thermometer ELARI SmartCare model YC-E13 (manufactured by Zhengyang Yuncheng Medical Technology Co. Ltd., China) to eliminate the thermal effect. Results. A complete clinical remission was achieved after one LOT session. Conclusions. Light-oxygen therapy in patients with cherry angiomas is an effective and safe curative technique.","PeriodicalId":489084,"journal":{"name":"Lazernaâ medicina","volume":"11 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135933401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of modes for safe application of selective micro-pulse individual retinal therapy of the macular zone using the modeling based on the theory of activated complex","authors":"E. V. Ivanova, P. L. Volodin","doi":"10.37895/2071-8004-2023-27-2-22-31","DOIUrl":"https://doi.org/10.37895/2071-8004-2023-27-2-22-31","url":null,"abstract":"Purpose: to make modeling of various modes of laser radiation, to assess the degree of damage to the retinal pigment epithelium and adjacent structures, and to determine modes and safety conditions of selective micro-pulse individual retinal therapy based on the theory of activated complex. Materials and methods. The authors have modeled the degree of damage to the chorioretinal complex and adjacent structures using the activated complex theory with the Eyring equation. The following definitions were used to determine the regime quality and safety conditions: micro-pulse mode is a mode with fixed values of micro-pulse duration, duty cycle and the number of pulses in the packet; power is a variable parameter. Efficiency is the ratio of the amount of denatured protein inside the retinal pigment epithelium layer to the total amount of protein in it. Selectivity is the ratio of the amount of denatured protein inside the retinal pigment epithelium layer to the total amount of denatured protein. Relative harmfulness is the ratio of denatured protein volume outside the retinal pigment epithelium to the volume of protein in it. Results and discussion. The quality of micro-pulse mode was found as depending on the selectivity value with efficiency equal to 90 %. With the efficiency value less than 50 %, the mode is non-selective, with more than 67 % – selective. Safety conditions for selective micro-pulse modes have been established, taking into account safety of the neurosensory retina and choroid in terms of relative harmfulness which should not exceed 1. Parameters at which micro-pulse modes have high values (more than 90 – 99) of efficiency and selectivity at the same time have been determined as well. It requires single pulse mode, micro pulse duration of 25 microseconds and power from 6 to 8 W. To expand the combination of parameters, it is necessary to be able to freely change them in increments of 1 pulse, 5 microseconds, 100 mW, with long interval and short duty cycle. These technical capabilities can be realized and implemented into clinical practice by manufacturers of laser devices. Conclusion. For selective micro-pulse individual retinal therapy of the macular zone with existing lasers, the following recommendation are to be observed: micro-pulse modes with pulse duration no more than 200 microseconds, short duty cycle less than 5 % and number of pulses in an envelope no more than 5; relative harmfulness less than one, radiation power selection, personalized patient’s characteristics.","PeriodicalId":489084,"journal":{"name":"Lazernaâ medicina","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135933410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The mechanism and kinetics of antianginal effect formation after laser therapy course in patients with angina pectoris","authors":"N. N. Streltsova, A. P. Vasilyev","doi":"10.37895/2071-8004-2023-27-2-16-21","DOIUrl":"https://doi.org/10.37895/2071-8004-2023-27-2-16-21","url":null,"abstract":"Purpose: To assess some mechanisms of antianginal effect formation under low-level infrared laser irradiation in patients with angina pectoris, as well as to clarify the kinetics of this clinical effect after laser therapy course. Materials and methods. 88 male patients, aged 54.2 ± 3.7, with angina pectoris of functional class II–III were examined. 63 patients of the main group had a ten-day course of laser therapy. 25 patients were included in the control group in which laser irradiation was only simulated. At the initial stage and one month after laser therapy or its imitation, and in the main group additionally after 3 and 6 months, bicycle ergometric tests were performed to determine exercise tolerance and evaluate the double product indicator at the level of initial (P1) and maximum (P2) threshold load, if its threshold power exceeded the initial one. Results and discussion. The increase of exercise tolerance was observed in 79.5 % of patients from the main group one month later and in 81.7 % three months later after finishing laser therapy course, with the increase in exercise tolerance by 19.1 W (+ 30.4 %; p = 0.023) and by 22.7 W (36.2 %; p = 0.009), respectively. The antianginal effect lasted for about 6 months of follow-up in 62.0 % of treated patients. The double product indicator reflecting myocardial oxygen consumption at P1 level after laser irradiation had a pronounced downward trend. This indicator increased at maximum load (P2) by 19.1 % (p = 0.04) and by 24.1 % (p = 0.006) during repeated examinations in 1 and 3 months, respectively. By the sixth month of observation, studied parameters returned to the initial levels. There were no statistically significant changes in the studied parameters in patients from the control group. Conclusion. The data obtained indicate that a ten-day course of laser therapy triggers high and long-lasting antianginal effect in patients with angina pectoris. The mechanism of its action is caused with the economization factor of cardiac activity and with the increase of coronary blood flow productivity.","PeriodicalId":489084,"journal":{"name":"Lazernaâ medicina","volume":"6 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135933409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Justification of the application of Raman-fluorescence diagnostics to assess dental status of the oral cavity","authors":"M. T. Alexandrov, D. G. Eganian, L. A. Mamedova, M. N. Podoinikova","doi":"10.37895/2071-8004-2023-27-2-32-41","DOIUrl":"https://doi.org/10.37895/2071-8004-2023-27-2-32-41","url":null,"abstract":"Purpose: To assess the influence of visibility, grayness and lighting conditions of the dentist’s workplace at the indicators of oral cavity homeostasis as well as to justify the application of digital Raman-fluorescence diagnostics for studying dental status of the oral cavity so as to exclude the subjective factor in visual indicators. Materials and methods. 90 patients took part in the trial. Group 1 (controls): participants with the controlled hygiene of their oral cavity and without pronounced dental pathologies; Group 2 (studied): 2A – patients with uncontrolled hygiene and concomitant unsatisfactory hygienic condition of their oral cavity, 2B – patients with controlled hygiene and previous unsatisfactory hygienic condition of their oral cavity. There were 30 patients in each group, and all of them had carious lesions. Patients of Groups 1 and 2A cleaned their teeth by the generally accepted scheme. In Group 2B, patients cleaned their teeth under control, and the procedure duration had been calculated individually by laser fluorescence diagnostics. In both groups, the degree of hard tissues mineralization was determined with the Raman diagnostics. Patients from the studied group were prescribed remineralisation therapy. Visual methods and Raman-fluorescence diagnostics were used to assess dental status of the oral cavity. Results and discussion. There was a significant improvement in all indicators in Group 2B compared to Group 2A; no changes were observed in the control group. Errors in the visual measurement of oral cavity dental status can range from 200 to 400%. To eliminate disadvantages of the visual assessment of the oral cavity, Raman-fluorescence diagnostics has to be applied, the results of which do not depend on color, grayness and lighting of the examined object. Conclusion. To eliminate disadvantages of the visual method for assessing the oral cavity condition, Raman-fluorescent diagnostics, which does not depend on color, grayness and lighting of the examined object, has to be applied. The Raman-fluorescent and visual diagnostics allow to objectively assess dental status of the oral cavity.","PeriodicalId":489084,"journal":{"name":"Lazernaâ medicina","volume":"5 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135933247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subthreshold micropulse laser light in diabetic macular edema (literature review)","authors":"A. O. Giyasova, N. R. Yangieva","doi":"10.37895/2071-8004-2023-27-2-42-47","DOIUrl":"https://doi.org/10.37895/2071-8004-2023-27-2-42-47","url":null,"abstract":"The authors present a review on analyzing techniques for the treatment of diabetic macular edema. Subthreshold micro-pulse laser light is an effective and safe technique for managing diabetic macular edema which can be prescribed repeatedly. The effectiveness of subthreshold micro-pulse laser light is increased in combination with pharmacological therapy which includes inhibitors of the vascular endothelial growth (VEGF) factor.","PeriodicalId":489084,"journal":{"name":"Lazernaâ medicina","volume":"16 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135933630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes after intraoperative photodynamic therapy in the combined treatment of locally advanced colon cancer","authors":"I. V. Krochek, R. D. Ibatullin, A. V. Lappa, A. E. Anchugova","doi":"10.37895/2071-8004-2023-27-2-8-15","DOIUrl":"https://doi.org/10.37895/2071-8004-2023-27-2-8-15","url":null,"abstract":"Purpose. To study outcomes after the combined treatment of locally advanced colon cancer with intraoperative photodynamic therapy. Materials and methods. 35 patients with locally advanced colon cancer were included in the trial. Patients from the main group (n = 17) had intraoperative photodynamic therapy in combination with elective surgery. Patients from the control group (n = 18) had only surgical treatment. For photodynamic therapy, photosensitizer Photolon and “Lakhta-Milon” diode laser with wavelength 662 nm and power up to 2.5 W were used. Laser light was delivered via a quartz polymer fiber with diameter 600 microns. Results and discussion. Better positive immediate and long-term outcomes were registered in patients with locally advanced colon cancer from the main group, if to compare with the control group (length of hospital stay, number of remissions, relapses and mortality). Conclusion: Intraoperative photodynamic therapy improves outcomes after the combined treatment of patients with locally advanced colon cancer.","PeriodicalId":489084,"journal":{"name":"Lazernaâ medicina","volume":"3 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135371757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}