术中光动力联合治疗局部晚期结肠癌疗效观察

I. V. Krochek, R. D. Ibatullin, A. V. Lappa, A. E. Anchugova
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摘要

目的。目的:探讨术中光动力联合治疗局部晚期结肠癌的疗效。材料和方法。试验包括35名局部晚期结肠癌患者。主组患者(n = 17)术中光动力治疗联合择期手术。对照组(n = 18)仅行手术治疗。光动力治疗采用光敏剂Photolon和波长662 nm、功率2.5 W的“Lakhta-Milon”二极管激光器。激光通过直径600微米的石英聚合物纤维传输。结果和讨论。如果与对照组比较(住院时间、缓解次数、复发次数和死亡率),主要组局部晚期结肠癌患者的近期和长期阳性结果都更好。结论:术中光动力治疗可改善局部晚期结肠癌患者联合治疗后的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Outcomes after intraoperative photodynamic therapy in the combined treatment of locally advanced colon cancer
Purpose. To study outcomes after the combined treatment of locally advanced colon cancer with intraoperative photodynamic therapy. Materials and methods. 35 patients with locally advanced colon cancer were included in the trial. Patients from the main group (n = 17) had intraoperative photodynamic therapy in combination with elective surgery. Patients from the control group (n = 18) had only surgical treatment. For photodynamic therapy, photosensitizer Photolon and “Lakhta-Milon” diode laser with wavelength 662 nm and power up to 2.5 W were used. Laser light was delivered via a quartz polymer fiber with diameter 600 microns. Results and discussion. Better positive immediate and long-term outcomes were registered in patients with locally advanced colon cancer from the main group, if to compare with the control group (length of hospital stay, number of remissions, relapses and mortality). Conclusion: Intraoperative photodynamic therapy improves outcomes after the combined treatment of patients with locally advanced colon cancer.
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