Primary Health Care Research and Development最新文献

{"title":"Barretos’ County Matrix Support in Public Health - Deployment and Initial Results","authors":"Guilherme Carvalho Freire, Martins Fideles dos Santos Neto, A. Sankarankutty, Miriam Cristina Marchioreto de Oliveira, Marilene Oliveira Simeão, Nathalia Figueiredo Maia, Nicole Mayara Dias Souza, A. Longatto-Filho, J. L. Brisotti, E. Mauad","doi":"10.15761/hpc.1000174","DOIUrl":"https://doi.org/10.15761/hpc.1000174","url":null,"abstract":"Aims: Brazil offers universal, integral and free healthcare to all its citizens through its Unified Health System (SUS). Within Brazil, the state of São Paulo has the most complex health network and comes closest to offering the comprehensive healthcare as per the guidelines of SUS. However, constraints to the system include a lack of integration and coordination between the basic healthcare network and specialty outpatient clinics, which hampers both proper access to specialties as well the return to basic care. This inefficiency feeds a pernicious cycle leading to waiting times for specialty care in excess of two years. Methods: In this article we describe the step-by-step implementation of an institutional and matrix support system between specialties and primary care in the county of Barretos, São Paulo, Brazil. Results: The initial results of this coordination and integration demonstrate the feasibility and excellent results such as the reduction in the need for referral to specialty clinics of up to 87%. Conclusion: Matrix support improved significantly the medical care and potentially can reduce costs as well. *Correspondence to: Adhemar Longatto-Filho, PhD, Molecular Oncology Research Center, Barretos Cancer Hospital/Pio XII Foundation, Brazil, Surgical Sciences Research Domain Life and Health Sciences Research Institute (ICVS) School of Medicine University of Minho, Campus de Gualtar, 4710-057 Braga – Portugal, Tel: +351253604827; E-mail: longatto16@hotmail.com or longatto@ med.uminho.pt","PeriodicalId":48703,"journal":{"name":"Primary Health Care Research and Development","volume":"32 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89608232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The in vitro Effects of Tryptamine, Harmine, and Harmaline on Leishmania tarentolae and the Possible Implications for Leishmaniasis","authors":"Jessica L. Wickline, Alexis Broedlow, Benjamin M. Dorsey, Kirk Eichenberg, Marjorie A. Jones","doi":"10.15761/hpc.1000171","DOIUrl":"https://doi.org/10.15761/hpc.1000171","url":null,"abstract":"Leishmaniasis is a disease caused by Leishmania parasitic protozoans affecting people in both the Eastern and Western Hemispheres. The secreted acid phosphatase enzymes (SAPs) are reported to play a critical role in infection by Leishmania. Thus, these enzymes are potential targets for Leishmania therapy. Tryptamines have various physiological effects and thus serve different purposes socially. Tryptamines are used in ritualistic ceremonies in countries where Leishmania cases are reported. In this work, tryptamine and two other indole derivatives, harmine and harmaline, were investigated. Harmine and harmaline were selected because of their presence in the biological materials used in some South American ritualistic ceremonies. We investigated the effects on axenic Leishmania tarentolae cell shape, motility, clumping, and viability as well as on the activity of secreted acid phosphatase (SAP) from L. tarentolae. An overall decrease in cell viability over a seven-day period and a small recovery in cell viability, only at lower concentrations of test compounds, were observed. These compounds were, in general, activators of L. tarentolae SAP activity. This is the first report of effects of these compounds on Leishmania secreted acid phosphatase activity in vitro. We speculate that those with Leishmania infections may be worsening their condition with the exposure to these compounds. *Correspondence to: Marjorie A Jones, Department of Chemistry, Illinois State University, Normal, IL 61790-4160, USA, E-mail: majone3@ilstu.edu","PeriodicalId":48703,"journal":{"name":"Primary Health Care Research and Development","volume":"45 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82701961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"UKMStrokIT: A web-based educational package tool for longer-term care of stroke patients: a pilot randomized controlled trial","authors":"Z Maisarah, Nik Nur Amr, Chang Zn, Ahmad Tmj, M Reenjaniswari, A. Saharuddin, Aziz Na","doi":"10.15761/hpc.1000159","DOIUrl":"https://doi.org/10.15761/hpc.1000159","url":null,"abstract":"","PeriodicalId":48703,"journal":{"name":"Primary Health Care Research and Development","volume":"21 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90398149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Usefulness of barrier function index based on water content and transepidermal water loss for evaluating efficacy of skin protective creams","authors":"T. Kubota, Yukina Watanabe, Anna Takahashi, Aki Sekine","doi":"10.15761/HPC.1000164","DOIUrl":"https://doi.org/10.15761/HPC.1000164","url":null,"abstract":"The functionality of skin protective creams containing a film forming agent for enhancing barrier function was evaluated from the viewpoint of skin roughness prevention. The subjects were 15 healthy adults (7 females) without skin disorders ranging in age from 21-24 years (mean 22.1 years). Three sites on the medial side of the left forearm were used for measurements; an untreated control where no cream was applied, a small area applied with skin protective cream containing barrier ingredients, and a small area applied with skin protective cream containing no barrier ingredients. After repeated tape stripping for 20 times, transepidermal water loss (TEWL) and water content in the stratum corneum (SC) after applying skin protective cream were determined over time in each subject. Barrier function index was calculated based on TEWL and water content in the SC, and used to evaluate the effects of the barrier ingredients. For the untreated control, the initial mean value obtained at 0 hours, and then 1, 2 and 3 hours after skin protective cream application were 0.79, 0.70, 0.65, and 0.62, respectively. Those values for areas applied with cream containing no barrier ingredients were 0.42, 0.44, 0.43, and 0.41, respectively, while they were 0.39, 0.42, 0.39, and 0.40, respectively, for the areas applied with cream containing barrier ingredients. That later group showed the lowest values at each measurement time. Notably, high efficacy was seen for the cream containing barrier ingredients from 0 to 2 hours after application. These findings indicate that barrier function index is useful for evaluating the efficacy of skin protective creams.","PeriodicalId":48703,"journal":{"name":"Primary Health Care Research and Development","volume":"43 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85311697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hughes-Stovin Syndrome or Vascular Behçet’s Disease?","authors":"S. Dumitru, A. Dragomir, F. Mihălțan","doi":"10.15761/hpc.1000173","DOIUrl":"https://doi.org/10.15761/hpc.1000173","url":null,"abstract":"Hughes-Stovin Syndrome is a very rare pathology of unknown etiology with a lethal potential. It is characterized by the association of pulmonary artery aneurysms and peripheral venous thrombosis. We report the case of a 33 years old man with no prior illnesses, who came in for hemoptysis in small quantities. Based on the clinical presentation, the radiological studies and the histopathological finding we made our diagnosis of Hughes-Stovin Syndrome. The response to treatment was very good and at the 12 months follow-up the patient was completely asymptomatic, with no new radiological lessions on chest CT. *Correspondence to: Silviu-Mihail Dumitru MD, Marius Nasta, National Institute of Pneumophtisiology, Romania, E-mail: Dumitrusm@gmail.com","PeriodicalId":48703,"journal":{"name":"Primary Health Care Research and Development","volume":"45 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88822651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Should our practice participate in the New CMS Primary Care First Initiative?","authors":"Mikila Lawless","doi":"10.15761/hpc.1000167","DOIUrl":"https://doi.org/10.15761/hpc.1000167","url":null,"abstract":"","PeriodicalId":48703,"journal":{"name":"Primary Health Care Research and Development","volume":"26 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73773145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alzheimer’s Disease: potential benefits of curcumin","authors":"James W. Anderson","doi":"10.15761/hpc.1000170","DOIUrl":"https://doi.org/10.15761/hpc.1000170","url":null,"abstract":"","PeriodicalId":48703,"journal":{"name":"Primary Health Care Research and Development","volume":"48 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76346880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a patient-centred model of community-based OPAT (CoPAT) service in Singapore","authors":"Xu Yi, Lim Su Fee, F. Aloweni, Chua Ying Ying, H. Ying","doi":"10.15761/hpc.1000169","DOIUrl":"https://doi.org/10.15761/hpc.1000169","url":null,"abstract":"There is a growing trend of expanding Outpatient Parenteral Antibiotics Therapy (OPAT) services to the community as it is more cost-effective for both patients and healthcare organisations. At the Singapore General Hospital (SGH), frail patients requiring intravenous (IV) antibiotics often have to prolong their hospitalisation to complete the course of treatment. Community OPAT (CoPAT) service is a joint effort between SGH Community Nursing and Department of Infectious Diseases. With the new CoPAT service, patients have the options of receiving their IV antibiotics at home rather than receiving treatment at the hospital or outpatient clinic. This case study described the process of providing CoPAT services in the community, its challenges and learning points and the positive outcomes of cost saving and improved patient experience. Early preliminary screening of suitable patients and good communication link among hospitals and community teams are essential in ensuring its success. *Correspondence to: Xu Yi, Senior Nurse Clinician (Community Nurse), RHSCommunity Nursing, Singapore General Hospital, Singapore, E-mail: xu.yi@ sgh.com.sg Received: August 27, 2019; Accepted: September 09, 2019; Published: September 12, 2019 Introduction Outpatient Parenteral Antibiotic Therapy (OPAT) refers to the approach for delivering intravenous (IV) antimicrobials in the outpatient setting or community [1]. OPAT service was first described in the United States in 1974 and was subsequently introduced to Singapore in 2002 [2]. This service requires a multidisciplinary team with expertise and experience in antimicrobial therapy for safety and long-term sustainability [3]. It is further recommended that the OPAT team provides an extension of services including laboratory testing, catheter care, regular nursing and physician assessments, follow-up, and adjustments as part of the optimal care to the existing primary illness, comorbidities and emerging complications [2]. Globally, there is a growing trend of expanding OPAT services to the community as it is cost-effective, and it also provides greater comfort to the patient when he/she receives the IV antibiotic at home [4]. OPAT improves patient’s satisfaction as it provides him/her the advantages of being able to resume his/her daily activities and having greater freedom and control at a familiar environment [5]. In additon, administering IV antibiotic at home reduces the risk of nosocomial complications as a result of prolonged hospitalisation [4]. In Singapore, OPAT services are mainly provided at specific outpatient clinics within acute hospitals. This service may not be accessible to patients who are frail or with limited mobility as it requires them to travel daily to the outpatient clinic and also incurs transportation costs. As a result, many of them would prefer to remain in the hospital till they receive the full course of IV antibiotics. This paper aims to describe the development of a patient-centred model o","PeriodicalId":48703,"journal":{"name":"Primary Health Care Research and Development","volume":"29 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87199211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social representations and food practices of people with Diabetes Mellitus Type 2","authors":"M. Amorim, Alessandra Hugo de Souza, N. Ramos, Maria Flávia Gazzinelli","doi":"10.15761/HPC.1000162","DOIUrl":"https://doi.org/10.15761/HPC.1000162","url":null,"abstract":"1Researcher, Center for Studies of Migration and Intercultural Relations, Lisbon, Portugal 2Nutricionist Specialist in Geriatric Nutrition, Master student in the Graduate Program in Vertebrate Biology-PUC Minas, Brazil 3Professor, Open University of Lisbon, Center for Studies of Migration and Intercultural Relations, Lisbon, Portugal 4Professor, The School of Nursing at Federal University of Minas Gerais, Belo Horizonte, Brazil","PeriodicalId":48703,"journal":{"name":"Primary Health Care Research and Development","volume":"104 3 Pt 2 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89681246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}