Clinical and Translational Imaging最新文献

{"title":"Head-to-head comparison of [18F]FDG PET and [68Ga]Ga-FAPI-04 PET in the diagnosis of gastric and pancreatic cancer: a systematic review and meta-analysis","authors":"Wanrun Xie, Bo Li, Zhenzhen Hong, Yi Zhang","doi":"10.1007/s40336-024-00633-4","DOIUrl":"https://doi.org/10.1007/s40336-024-00633-4","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose</h3><p>Our meta-analysis aimed to compare the positivity rates of [⁶⁸Ga]Ga-FAPI-04 PET and [¹⁸F]FDG PET in gastric and pancreatic cancer.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>We conducted a comprehensive search of PubMed, Embase, and Web of Science databases up to May 2023. The selected studies focused on evaluating the positivity rates of [¹⁸F]FDG PET and [⁶⁸Ga]Ga-FAPI-04 PET in detecting gastric and pancreatic cancer.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>A total of 2,401 studies were screened and 13 articles were finally included. The positivity rates of [¹⁸F]FDG PET for primary gastric cancer, lymph node and peritoneal metastases were 0.74 [95% confidence interval (CI): 0.55–0.89], 0.49 (95% CI: 0.33–0.65) and 0.52 (95% CI: 0.37–0.67), respectively. On the other hand, [⁶⁸Ga]Ga-FAPI-04 PET demonstrated significantly higher positivity rates at 0.98 (95% CI: 0.92-1.00), 0.76 (95% CI: 0.60–0.89) and 0.99 (95% CI: 0.93-1.00) (<i>P</i> &lt; 0.01,<i>P</i> = 0.02, <i>P</i> &lt; 0.01), respectively. For pancreatic cancer, [¹⁸F]FDG PET showed positivity rates of 0.93 (95% CI: 0.76-1.00) and 0.46 (95% CI: 0.23–0.69) for primary cancer and lymph node metastases, respectively. In comparison, [⁶⁸Ga]Ga-FAPI-04 PET showed similar positivity rates of 1.00 (95% CI: 0.94-1.00) and 0.68 (95% CI: 0.40–0.90), (<i>P</i> = 0.27, 0.23). There was no significant difference in histopathological positivity rates for signet ring cell carcinoma and TNM stages I and II-IV (<i>P</i> = 0.96, 0.85,0.56).</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>[⁶⁸Ga]Ga-FAPI-04 PET exhibited a higher positivity rate compared to [¹⁸F]FDG PET in the detection of primary gastric cancer, lymph node and peritoneal metastases. For pancreatic cancer, both [¹⁸F]FDG PET and [⁶⁸Ga]Ga-FAPI-04 PET demonstrated comparable, high positivity rates for primary cancer diagnosis and lymph node metastasis detection. There is still a requirement for more extensive and forward-looking research in this field.</p>","PeriodicalId":48600,"journal":{"name":"Clinical and Translational Imaging","volume":"1 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140595365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early response assessment to targeted therapy in metastatic clear cell renal cancer using 68Ga-PSMA-11 PET/CT and comparison with CECT: a feasibility study","authors":"Piyush Aggarwal, Harmandeep Singh, Chandan K. Das, Ravimohan S. Mavuduru, Anupam Lal, Nandita Kakkar, Rajender Kumar, Ujjwal Gorsi, Pratibha Prashar, Bhagwant R. Mittal","doi":"10.1007/s40336-024-00627-2","DOIUrl":"https://doi.org/10.1007/s40336-024-00627-2","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose</h3><p>Contrast-enhanced computed tomography (CECT) underestimates the response to targeted therapy in metastatic renal cell cancer (mRCC) using Response Assessment Criteria In Solid Tumors (RECIST) v1.1, creating an unmet need for better imaging biomarkers for early response assessment. This study explores the feasibility of early response assessment to targeted therapy in metastatic clear cell RCC (ccRCC) using ⁶⁸Ga-PSMA-11 PET/CT.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>After informed consent, adult patients with biopsy-proven metastatic ccRCC planned for targeted therapy were recruited in this prospective observational pilot study from May 2021 to December 2022. ⁶⁸Ga-PSMA-11 PET/CT was conducted at baseline and one and three months post-treatment. The concordance between PET and CT responses at one and three months was analysed. Follow-up and comparison of progression-free survival (PFS) between responders and non-responders on PET and CT was done.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>Twenty-one metastatic ccRCC patients were included in the final analysis. The response assessment on PET and CT was discordant in 15 out of 21 patients (~ 71%) at one month and in nine out of 21 patients (~ 43%) at three months. There was no significant difference between the median PFS of responders vs non-responders on CT at one (14 m vs. 12 m, p = 0.9) and three months (14 m vs. 12 m, p = 0.6). However, a higher difference in median PFS was observed between responders and non-responders on PET at one (PFS 14 m vs. 1 m, p &lt; 0.001) and three months (PFS 14 m vs. 3 m, p = 0.28), respectively.</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>Early response assessment with ⁶⁸Ga-PSMA-11 PET/CT is feasible and provides more accurate prognostic information than CECT in metastatic clear cell RCC patients undergoing targeted therapy.</p><p>Trial registration number</p><p>CTRI/2021/05/033805 (date of registration: 25/05/21)</p>","PeriodicalId":48600,"journal":{"name":"Clinical and Translational Imaging","volume":"10 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140595128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[18F]FDG PET/CT imaging of spinal infections","authors":"Erik T. te Beek, Marc R. J. ten Broek, Sakar Abdul-Fatah, Andor W. J. M. Glaudemans","doi":"10.1007/s40336-024-00629-0","DOIUrl":"https://doi.org/10.1007/s40336-024-00629-0","url":null,"abstract":"<p>The annual incidence of spinal infections has been rising significantly over the last years and is expected to increase even further. Spinal infections may include infection of the vertebral body and intervertebral disc (spondylodiscitis), paravertebral abscess, epidural abscess and septic arthritis of the facet joints. Positron emission tomography (PET) with [¹⁸F]FDG has high sensitivity for detecting spinal infections, may help in differentiating between spinal infection subtypes and is able to detect dissemination of infection outside the spine. [¹⁸F]FDG PET/CT is especially indicated if MRI is inconclusive, in patients with contra-indications for MRI, in postoperative patients with or without spinal hardware and in patients with bacteremia to find foci of infection. Here, we present a concise overview of the spectrum of [¹⁸F]FDG PET/CT imaging findings in spinal infections.</p>","PeriodicalId":48600,"journal":{"name":"Clinical and Translational Imaging","volume":"50 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140595132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric congenital pulmonary malformations: key findings at imaging","authors":"Giulia Fichera, Annachiara Cavaliere, Francesco Causin, Monica Zuliani, Gianni Bisogno, Federico Rea, Roberto Stramare, Chiara Giraudo","doi":"10.1007/s40336-024-00632-5","DOIUrl":"https://doi.org/10.1007/s40336-024-00632-5","url":null,"abstract":"<p>Pediatric congenital pulmonary malformations are rare abnormalities which may affect airways, pulmonary parenchyma, and vasculature and diagnostic imaging plays a significant role in their identification and characterization. Although, nowadays, often the diagnosis of this heterogeneous group of malformations is performed prenatally by ultrasound and/or fetal magnetic resonance, after birth, computed tomography represents the main technique. Radiographs are often used as first line diagnostic tool while magnetic resonance demonstrated to be especially beneficial to investigate some malformations such as bronchogenic cysts. Therefore, radiologists should be aware of the main features associated with such alterations to guarantee a prompt diagnosis and, if necessary, guide towards the optimal treatment. Aim of this pictorial review is to provide a comprehensive overview of the typical features of congenital pulmonary malformations at imaging supporting general and pediatric radiologists in the diagnostic process.</p>","PeriodicalId":48600,"journal":{"name":"Clinical and Translational Imaging","volume":"54 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140595341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Equivocal bone lesions on PSMA PET/CT: systematic review and meta-analysis on their prevalence and malignancy rate","authors":"Sungmin Woo, Daniel Freedman, Anton S. Becker, Doris Leithner, Marius E. Mayerhoefer, Kent P. Friedman, Yuki Arita, Sangwon Han, Irene A. Burger, Samir S. Taneja, David R. Wise, Michael J. Zelefsky, Hebert A. Vargas","doi":"10.1007/s40336-024-00631-6","DOIUrl":"https://doi.org/10.1007/s40336-024-00631-6","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose</h3><p>Prostate-specific membrane antigen (PSMA) PET/CT has an established reliable diagnostic performance for detecting metastases in prostate cancer. However, there are increasing instances of scans demonstrating equivocal bone lesions, with non-specific uptake and without a definite benign or malignant CT correlate. To date, the prevalence, malignancy rate, and relationship with radioligand type ([¹⁸F] PSMA-1007 vs. others ([⁶⁸Ga]Ga-PSMA-11 and [¹⁸F] DCFPyL) for these equivocal lesions have not been extensively established.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>A systematic review and meta-analysis was conducted on equivocal bone lesions. Pubmed and EMBASE were searched up to December 11, 2023. Quality of the studies was evaluated using QUADAS-2. The following proportions were pooled using random-effects model: (1) prevalence of equivocal bone lesions (i.e., number of patients with one or more equivocal bone lesions/number of patients with PSMA PET/CT) and (2) their malignancy rates (i.e., number of metastases/number of equivocal bone lesions). Subgroup analyses based on radioligand type, clinical setting, and definition of equivocal bone lesion were performed.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>Twenty-five studies (4484 patients) were included. Pooled prevalence of equivocal bone lesions was 20% (95%CI, 12–31%). [¹⁸F]PSMA-1007 was associated with a greater prevalence of equivocal lesions compared with other radioligands: 36% (95%CI 26–48%) vs. 8% (95%CI, 4–14%), respectively, <i>p</i> &lt; 0.01. Pooled malignancy rate of equivocal bone lesions was 14% (95%CI, 7–25%). [¹⁸F]PSMA-1007 was associated with a lower malignancy rate compared to other radioligands: 8% (95%CI, 3–19%) vs. 29% (95%CI, 17–44%), respectively, <i>p</i> = 0.01. There were no signficant difference in prevalence or malignancy rate between subgroups stratified to clinical setting or definition of equivocal bone lesions (<i>p</i> = 0.32–0.60).</p><h3 data-test=\"abstract-sub-heading\">Conclusions</h3><p>Equivocal bone lesions are often encountered on PSMA PET/CT but exihibit a low malignancy rate. Compared to other radioligands, [¹⁸F]PSMA-1007 requires special attention as it is associated with a higher frequency and lower rate of metastasis.</p>","PeriodicalId":48600,"journal":{"name":"Clinical and Translational Imaging","volume":"11 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140325662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Denoising approaches by SubtlePET™ artificial intelligence in positron emission tomography (PET) for clinical routine application","authors":"Marco De Summa, Maria Rosaria Ruggiero, Sandro Spinosa, Giulio Iachetti, Susanna Esposito, Salvatore Annunziata, Daniele Antonio Pizzuto","doi":"10.1007/s40336-024-00625-4","DOIUrl":"https://doi.org/10.1007/s40336-024-00625-4","url":null,"abstract":"<p>Positron emission tomography (PET) plays an important role in the diagnosis and surveillance of neoplastic diseases. PET images may show higher noise levels than other imaging modalities, especially in a dose- or time-saving approach. Artificial Intelligence techniques can improve the signal-to-noise ratio in PET image reconstruction. Deep learning approaches have made significant advances in comprehensive data retrieval and de-noising. Artificial Intelligence de-noising in PET is a very promising approach that could allow shorter scan times or lower radiopharmaceutical dose administration. We reviewed studies about the de-noising AI-driven PET images, i.e., by SubtlePET™ AI tool, according to the following items: (1) retrieval of complete PET data acquired with reduced scan time; (2) reconstruction of PET images with low-count statistics by reducing radiopharmaceutical doses; (3) impact of artificial intelligence-based de-noising on PET radiomics. We evaluated their implementability in PET image reconstruction to increase the signal-to-noise ratio and image definition. This approach seems promising to positively impact patient healthcare—especially in pediatric patients—and overall diagnostic procedures reducing the cost of radiopharmaceuticals and increasing productivity and efficiency.</p>","PeriodicalId":48600,"journal":{"name":"Clinical and Translational Imaging","volume":"15 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140105328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of diffuse bone marrow involvement on 18F-fluoro-D-glucose PET/computed tomography","authors":"Tong Zhang, Lei Wang, Funing Yang, Hongjia Wang, Ping Li","doi":"10.1007/s40336-024-00626-3","DOIUrl":"https://doi.org/10.1007/s40336-024-00626-3","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose</h3><p>This study aims to investigate the role of bone marrow (BM) FDG uptake distribution in assessing pathological status of BM with diffusely increased FDG uptake.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>We retrospectively analyzed one hundred and thirty-four PET/CT scans with diffusely hypermetabolic BM, which involved forty-nine patients with BM malignant infiltration (BMI) and eighty-five patients with benign BM disorders. The maximum standardized uptake values (SUVmax) of axial skeletons, appendicular skeletons, and the range of humerus FDG uptake were measured. The clinical and laboratory data were collected. Multivariate logistic regression analysis and receiver operating characteristic (ROC) curve were used to evaluate the risk factors for BMI and discriminative ability of above indicators for the pathology status of BM.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>In patients with diffusely hypermetabolic BM, both the glucose metabolism of axial and appendicular skeletons was higher in BMI than BM benign disorders. The multivariate logistic regression analysis (stepwise) revealed age (odds ratio [OR] 1.073; 95%CI, 1.031–1.117; <i>P</i> = 0.001), femurs SUVmax (OR 2.058; 95%CI, 1.317–3.218; <i>P</i> = 0.002), neutrophil count (OR 0.805; 95%CI, 0.718–0.902; <i>P</i> &lt; 0.001) and range of humerus FDG uptake (OR 11.335; 95%CI, 2.831–45.377; <i>P</i> = 0.001) were associated with BMI. Combined diagnosis had the highest ROC value (AUC 0.918; 95%CI, 0.864–0.973; <i>P</i> &lt; 0.001) with a sensitivity of 89.8% and specificity of 85.9%.</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>The BM activity of the appendicular skeleton was more significant in distinguishing BM malignant and benign disorders. Range of humerus FDG uptake combined femurs SUVmax, neutrophil count and age was reliable for assessing diffuse BM involvement.</p>","PeriodicalId":48600,"journal":{"name":"Clinical and Translational Imaging","volume":"62 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140025210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sentinel node biopsy in gynaecological cancers: state of art and future perspectives","authors":"","doi":"10.1007/s40336-024-00619-2","DOIUrl":"https://doi.org/10.1007/s40336-024-00619-2","url":null,"abstract":"<h3>Abstract</h3> <span> <h3>Purpose</h3> <p>This review aims to provide an overview of current knowledge and future perspectives on sentinel node biopsy in gynaecological cancers.</p> </span> <span> <h3>Methods</h3> <p>Literature research in the PubMed/MEDLINE database was carried out to identify relevant studies on sentinel node biopsy in gynaecological cancers. We selected only original studies, published in the English language and including a minimum of nine patients.</p> </span> <span> <h3>Results</h3> <p>The most relevant results on sentinel node biopsy in gynaecological cancers were summed up, focusing on clinical indications, technical aspects, preoperative and intraoperative procedures and the latest technological advances.</p> </span> <span> <h3>Conclusion</h3> <p>Sentinel node biopsy has been widely validated in well-selected patients with early-stage vulvar, cervical and endometrial cancers. It is essential to standardise the acquisition protocol, including SPECT/CT imaging, for an improved surgical planning and a personalised approach. Recent technological advances, such as hybrid tracers and intraoperative tools, may efficiently guide gynaecological cancer surgery.</p> </span>","PeriodicalId":48600,"journal":{"name":"Clinical and Translational Imaging","volume":"28 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140026437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prognostic role of metabolic tumor burden in 18F-FDG PET/CT in the primary staging of rectal cancers","authors":"","doi":"10.1007/s40336-024-00621-8","DOIUrl":"https://doi.org/10.1007/s40336-024-00621-8","url":null,"abstract":"<h3>Abstract</h3> <span> <h3>Introduction</h3> <p>The prognostic value of FDG PET/CT metabolic tumor burden has been established in various solid tumors, but its significance in the staging of rectal cancer remains underexplored. This study aimed to investigate the prognostic role of FDG PET/CT metabolic tumor burden in the primary staging of rectal cancer.</p> </span> <span> <h3>Methods</h3> <p>A retrospective analysis was conducted on 82 consecutive histology-proven rectal cancer patients, including 30 females (37%), with a mean age of 60.8 years. These patients underwent staging FDG PET/CT, and various metabolic tumor burden parameters (tuSUVmax, tuMTV, wbMTV, tuTLG, wbTLG) were calculated. The study assessed the correlation between metabolic tumor burden parameters and overall survival (OS), progression-free survival (PFS), as well as histopathology, clinical staging, performance status, bone-mineral indexes, hematology, and therapy management strategies.</p> </span> <span> <h3>Results</h3> <p>The study revealed that metabolic tumor burden, along with the presence of sarcopenia and absence of surgery, were significantly and independently associated with overall survival. Notably, a wbTLG cutoff value of 354 effectively discriminated survivors from non-survivors (<em>p</em> = 0.0007) with 83% specificity. Furthermore, higher whole-body tumor burden (wbTLG: <em>p</em> = 0.0090) and low body mass index (<em>p</em> = 0.0231) were significantly linked to an increased risk of disease progression.</p> </span> <span> <h3>Conclusion</h3> <p>This research suggests that whole-body tumor burden assessed through staging FDG PET/CT can serve as an independent imaging biomarker for prognostication in rectal cancer patients.</p> </span>","PeriodicalId":48600,"journal":{"name":"Clinical and Translational Imaging","volume":"68 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140034409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender balance in skeletal radiology: suffrage rather than suffering?","authors":"","doi":"10.1007/s40336-024-00623-6","DOIUrl":"https://doi.org/10.1007/s40336-024-00623-6","url":null,"abstract":"<h3>Abstract</h3> <p>Reaching equity in the distribution of opportunity between men and women is in the agenda of premier international agencies worldwide, and in the last decades a significant improvement in women’s access to care and education as well as in terms of equality in the labor market has been achieved. In the medical field and, in particular, in radiology, the number of women progressively increased but still much has to be done to guarantee equal opportunities. Aiming to provide an overview of the European musculoskeletal imaging community regarding gender equity, we developed a 39-item survey addressed to the 2481 members of the European Society of Musculoskeletal Imaging (ESSR). The responses of the 74 participants (3%) demonstrated that for most of the addressed clinical, academic, and ESSR-related questions, no statistically significant differences gender-related occurred except for instance for the experienced gender discrimination, which affected women more often (55% of women vs 21.9% of men; <em>p</em> = 0.017). Despite the low participation rate, our results suggest that there is hope of ‘suffrage’ with leadership and steering roles in the Executive Committee and Subcommittees and a real-time reduction in the gender gap.</p>","PeriodicalId":48600,"journal":{"name":"Clinical and Translational Imaging","volume":"4 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140004967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}