Timočki medicinski glasnik最新文献

{"title":"Analysis of arterial pressure variability by measuring pressure on both arms and as a function of time in patients with newly discovered hypertension","authors":"Maja Mladenović, Zoran Joksimović, Igor Đorđioski, Anastasija Raščanin, Mila Bastać, Stanislav Tadić, Jasmina Strajnić, Dušan Bastać","doi":"10.5937/tmg2302039m","DOIUrl":"https://doi.org/10.5937/tmg2302039m","url":null,"abstract":"INTRODUCTION At the initial office visit, blood pressure should be measured in both arms, ideally with electronic devices that can measure them simultaneously. SBP difference between arms >10 mmHg must be confirmed by repeated measurements. If confirmed, the arm with the higher blood pressure should be used for all subsequent measurements, as its values more accurately reflect the level of blood pressure in the major arteries. Using blood pressure readings on the arm with higher pressure improves outcome prediction. A consistent difference in SBP between the arms >15 to 20 mmHg may be due to atherosclerosis and restriction of the large intrathoracic or supraclavicular arteries, necessitating investigation of arterial disease. The blood pressure values on the right and left brachialis arteries differ in most cases, and the higher one is taken as more accurate. Prognostic significance: for each 10 mmHg difference according to Agarwal (2008), the relative risk of total mortality increases by 24%. In order to accurately assess the degree of hypertension, the spontaneous variability of pressure as a function of time and the pressure difference between the arms must be taken into account. WORK OBJECTIVES: 1. Analysis of spontaneous blood pressure variability upon arrival and repeated after 5 to 30 minutes; 2. Blood pressure differences between the left (LR) and right arm (DR). MATERIALS AND METHODS: A prospective study was conducted from the database of the \"Dr. Bastać\" Internal Medicine Practice on 26 patients, average age 58±12 years, with newly discovered hypertension by measuring blood pressure with the indirect manometer method at the first examination immediately after arrival and after 15 minutes. The control group consists of 28 patients who do not have hypertension. The data were statistically processed with the Student's T test. WORK RESULTS The mean value (Xsr) of systolic and diastolic blood pressure (SKP/DKP) of the examined group on arrival is 166/92 mmHg on the right hand (DR), and 161/93 mmHg on the left hand (LR). and after rest at DR 153/90 mmHg and LR 149/87. There is a statistically highly significant difference especially between the CAP on the hands - it is always higher on the right hand by an average of 5 mmHg (p=0.002) and 4 mmHg after rest. Spontaneous variability was determined in 10 (40%) subjects where there was a statistically significant drop in tension after rest. After a 15-minute rest, the significance of pressure differences between arms is maintained, but the high variability of 40% post-rest pressure variability is lost. CONCLUSION: Pressure on arrival in newly diagnosed untreated patients is always higher on the right arm by an average of 5 mmHg (p=0.002), and after rest 4 mmHg, this difference is maintained. Spontaneous variability was determined in 10 (40%) subjects where there was a statistically significant drop in tension after rest. After 15 minutes of rest, the significance of the pressure differences ","PeriodicalId":484631,"journal":{"name":"Timočki medicinski glasnik","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135213572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic value of inflammatory markers in patients with acute pancreatitis","authors":"Milanka Stojanović, Nadežda Stojčić","doi":"10.5937/tmg2302049s","DOIUrl":"https://doi.org/10.5937/tmg2302049s","url":null,"abstract":"Introduction: Acute pancreatitis (AP) is a sudden inflammatory reaction that causes autodigestion of the pancreas, edema, bleeding, and can lead to pancreatic necrosis and necrosis of the surrounding tissue. Since the initial symptoms of mild, moderate and severe pancreatitis are the same, doctors often cannot determine the severity of AP with certainty based on the first examination. Aim of the work: Numerous biomarkers have been studied as potential early predictors of the severity of this disease, so that treatment can be optimally adapted to prevent complications. The aim of the paper is to provide an overview of the most important inflammatory markers that are used, or can potentially be used to determine the severity of acute pancreatitis. Inflammatory markers: Markers of inflammation in AP are: the hormone procalcitonin, then reactants of the acute phase such as C-reactive protein, serum amyloid A, pentraxin 3; enzymes: polymorphonuclear elastase, phospholipase A2, myeloperoxidase; cytokines: interleukins (IL-6, IL-8, IL-17) and tumor necrosis factor (TNF-a). Conclusion: The most frequently determined parameter in clinical practice is CRP, as a non-specific marker of inflammatory diseases. The disadvantage in determining this parameter is that the maximum serum value is reached only 72 hours after the onset of AP symptoms. Numerous biomarkers have proven to be more sensitive for determining the severity of AP, of which procalcitonin stands out, which has been widely used in recent years, for the early prognosis of the development of local complications and multiorgan failure in AP. Cytokine determination is increasingly part of clinical practice. The most commonly used IL-6 is a sensitive and specific marker for predicting organ failure in severe AP","PeriodicalId":484631,"journal":{"name":"Timočki medicinski glasnik","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135213263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dr. Sigismund Krakow-Kladowski days: \"Honor beyond life\"","authors":"Ranko Jakovljević","doi":"10.5937/tmg2302054j","DOIUrl":"https://doi.org/10.5937/tmg2302054j","url":null,"abstract":"This paper presents biographical data and details related to service and life in Kladovo in 1903-1907. Dr. Sigismund Krakow and his ancestors.","PeriodicalId":484631,"journal":{"name":"Timočki medicinski glasnik","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135213277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biodiversity and seasonal distribution of ticks in southeastern Serbia","authors":"Ivan Pavlović, Dragana Lazarević","doi":"10.5937/tmg2302045p","DOIUrl":"https://doi.org/10.5937/tmg2302045p","url":null,"abstract":"Ticks are a relatively small group of hematophagous arthropods distributed in three families: Argasidae, Ixodidae and Nuttalliellidae. Ticks are found all over the world and we find them on land and on islands, and even in Antarctica, where seabirds are parasitized by the Northern Memoirs endemic species. They find all types of climates favourable, as well as the temperatures from +4°C and up. They are common in places where there is a large fluctuation of animals. The most common hosts are mammals, but in their absence they can be found on birds and reptiles. Ticks belong to a group of arthropods that are of exceptional biomedical importance due to their role as vectors of various types of diseases and the immediate harmful effects caused by the hematophagous diet. During research in domestic animals and humans in the area of southeastern Serbia, the prevalence of Ixodes ricinus, Dermacentor marginatus, D.pictus, Rhipicephalus sanguineus, R.bursa, Haemaphysalis punctata and He.inermis was established.","PeriodicalId":484631,"journal":{"name":"Timočki medicinski glasnik","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135213568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pathological finding of auditory evoked potentials in patients with vertebral artery hypoplasia associated with posterior circulation stroke","authors":"Biljana Živadinović, Stefan Todorović, Eva Antić, Mina Stojković, Milan Janković","doi":"10.5937/tmg2302035q","DOIUrl":"https://doi.org/10.5937/tmg2302035q","url":null,"abstract":"The aim of the paper was to determine clinical significance of pathological finding and characteristics of auditory evoked potentials (AEP) in patients with posterior circulation stroke caused by vertebral artery hypoplasia (VAH). The study enrolled 71 patients, 31 of them had posterior circulation stroke. The results of the examinations showed that pathological AEP finding was statistically significantly correlated with posterior circulation stroke (PCS) finding. Changes in AEP amplitude presented a prominent feature of stroke caused by vertebral artery hypoplasia and require further clinical investigations.","PeriodicalId":484631,"journal":{"name":"Timočki medicinski glasnik","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135213575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}