Analysis of arterial pressure variability by measuring pressure on both arms and as a function of time in patients with newly discovered hypertension

Maja Mladenović, Zoran Joksimović, Igor Đorđioski, Anastasija Raščanin, Mila Bastać, Stanislav Tadić, Jasmina Strajnić, Dušan Bastać
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Abstract

INTRODUCTION At the initial office visit, blood pressure should be measured in both arms, ideally with electronic devices that can measure them simultaneously. SBP difference between arms >10 mmHg must be confirmed by repeated measurements. If confirmed, the arm with the higher blood pressure should be used for all subsequent measurements, as its values more accurately reflect the level of blood pressure in the major arteries. Using blood pressure readings on the arm with higher pressure improves outcome prediction. A consistent difference in SBP between the arms >15 to 20 mmHg may be due to atherosclerosis and restriction of the large intrathoracic or supraclavicular arteries, necessitating investigation of arterial disease. The blood pressure values on the right and left brachialis arteries differ in most cases, and the higher one is taken as more accurate. Prognostic significance: for each 10 mmHg difference according to Agarwal (2008), the relative risk of total mortality increases by 24%. In order to accurately assess the degree of hypertension, the spontaneous variability of pressure as a function of time and the pressure difference between the arms must be taken into account. WORK OBJECTIVES: 1. Analysis of spontaneous blood pressure variability upon arrival and repeated after 5 to 30 minutes; 2. Blood pressure differences between the left (LR) and right arm (DR). MATERIALS AND METHODS: A prospective study was conducted from the database of the "Dr. Bastać" Internal Medicine Practice on 26 patients, average age 58±12 years, with newly discovered hypertension by measuring blood pressure with the indirect manometer method at the first examination immediately after arrival and after 15 minutes. The control group consists of 28 patients who do not have hypertension. The data were statistically processed with the Student's T test. WORK RESULTS The mean value (Xsr) of systolic and diastolic blood pressure (SKP/DKP) of the examined group on arrival is 166/92 mmHg on the right hand (DR), and 161/93 mmHg on the left hand (LR). and after rest at DR 153/90 mmHg and LR 149/87. There is a statistically highly significant difference especially between the CAP on the hands - it is always higher on the right hand by an average of 5 mmHg (p=0.002) and 4 mmHg after rest. Spontaneous variability was determined in 10 (40%) subjects where there was a statistically significant drop in tension after rest. After a 15-minute rest, the significance of pressure differences between arms is maintained, but the high variability of 40% post-rest pressure variability is lost. CONCLUSION: Pressure on arrival in newly diagnosed untreated patients is always higher on the right arm by an average of 5 mmHg (p=0.002), and after rest 4 mmHg, this difference is maintained. Spontaneous variability was determined in 10 (40%) subjects where there was a statistically significant drop in tension after rest. After 15 minutes of rest, the significance of the pressure differences between the arms is maintained, but the high pressure variability is lost.
新发现高血压患者通过测量双臂压力和随时间变化的动脉压力变异性分析
在初次就诊时,应测量双臂的血压,最好使用可以同时测量的电子设备。两臂收缩压差≤10mmhg必须通过反复测量确认。如果得到证实,应将血压较高的手臂用于所有后续测量,因为其值更准确地反映了大动脉的血压水平。在血压较高的手臂上使用血压读数可以改善预后预测。15 ~ 20 mmHg臂间收缩压的一致差异可能是由于动脉粥样硬化和胸内或锁骨上大动脉的限制,需要对动脉疾病进行调查。在大多数情况下,左右肱动脉的血压值不同,越高越准确。预后意义:根据Agarwal(2008),每10毫米汞柱差异,总死亡率的相对风险增加24%。为了准确地评估高血压的程度,必须考虑压力随时间的自发变异性和两臂之间的压差。工作目标:分析患者到达时的自发性血压变异性,5 ~ 30分钟后重复分析;2. 左臂(LR)和右臂(DR)的血压差。材料与方法:从“Dr. bastazi”内科实践数据库中选取26例新发现高血压患者,平均年龄58±12岁,在到达后立即进行第一次检查时和15分钟后用间接血压计法测量血压。对照组由28名无高血压的患者组成。数据采用Student’s T检验进行统计处理。工作结果检查组到达时收缩压和舒张压(SKP/DKP)的平均值(Xsr)为右侧(DR) 166/92 mmHg,左侧(LR) 161/93 mmHg。休息后DR为153/90 mmHg, LR为149/87。在统计上有非常显著的差异,特别是在手部的CAP之间——休息后右手的CAP平均高出5毫米汞柱(p=0.002),而休息后右手的CAP平均高出4毫米汞柱。在10名(40%)受试者中确定了自发变异性,这些受试者在休息后的紧张程度有统计学意义的下降。休息15分钟后,臂间压力差异的显著性得以维持,但休息后40%的高变异性消失。结论:新诊断的未治疗患者到达时右臂压力平均高5 mmHg (p=0.002),休息后保持4 mmHg。在10名(40%)受试者中确定了自发变异性,这些受试者在休息后的紧张程度有统计学意义的下降。休息15分钟后,手臂间压差的意义得到维持,但高压变异性丧失。
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