D. Om, Mrs Shajina M, M. Pk, Mr Jeeva James, D. Ml
{"title":"A retrospective correlative study on serum testosterone level and type-2 diabetes","authors":"D. Om, Mrs Shajina M, M. Pk, Mr Jeeva James, D. Ml","doi":"10.33545/26647222.2024.v6.i1a.49","DOIUrl":"https://doi.org/10.33545/26647222.2024.v6.i1a.49","url":null,"abstract":"","PeriodicalId":484171,"journal":{"name":"International Journal of Pharmacy and Pharmaceutical Science","volume":"49 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140515980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erin Xavier, Irien M George, Jesteena Jacob, Dr. Lincy George
{"title":"Assessment of role of FRIDs and PIMS in medication related fall in geriatric population","authors":"Erin Xavier, Irien M George, Jesteena Jacob, Dr. Lincy George","doi":"10.33545/26647222.2023.v5.i2a.42","DOIUrl":"https://doi.org/10.33545/26647222.2023.v5.i2a.42","url":null,"abstract":"Background: Falls are the leading cause of injuries among older adults. Pharmacological factors that place the elderly at greater risk of drug-related side effects include changes in body composition, serum albumin, total body water, and hepatic and renal functioning. Drug use is one of the most modifiable risk factors for falls and falls-related injuries. The simultaneous use of several medications is an important risk factor for injurious falls in older people. Aim: To assess the role of fall risk increasing drugs and potentially inappropriate medications in medication related fall in geriatric population. To identify and to prepare a report about the drugs causing fall. Methods: A prospective observational study was conducted in general medicine, cardiology, orthopedics and surgery department of a tertiary care hospital. The study included both male and female patient aged above 65 years taking fall risk increasing drugs as past medications. The study population included 109 patients. The documented data were analyzed by statistical, graphical method. Result and Discussion: The study showed that fall risk increasing drugs is a major risk for falls. Demographic and clinical data was collected and medication reviewed using John Hopkins fall risk assessment tool and STOPP criteria. The mean age of patients were 73 years. Most significant risk of fall was found in cardiovascular and antihypertensive drugs. Other major risk factors in elderly are age, female gender, fall history, poly pharmacy. Potentially inappropriate medication was found to be a contributing factor for falls in elderly. Conclusion: The study has clearly demonstrated that fall risk increasing drugs and potentially inappropriate medication increases the risk of fall in geriatric population. This study helped to identify the risk factors leading to fall in geriatric population like age, gender, poly pharmacy. Female gender, fall history, use of patient care equipment, limited mobility, altered cognition.","PeriodicalId":484171,"journal":{"name":"International Journal of Pharmacy and Pharmaceutical Science","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136004689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pharmaceutical assessment of body lotion: A herbal formulation and its potential benefits","authors":"Sunil Mishra, Dr. Shashank Tiwari, Kartikay Prakash, Prachi Jaiswal, Harsh Rajpoot","doi":"10.33545/26647222.2023.v5.i2a.41","DOIUrl":"https://doi.org/10.33545/26647222.2023.v5.i2a.41","url":null,"abstract":"Background: Protective layers of skin cover the body. Plant-based herbal body lotion soothes and moisturises. Treatments commonly include succulent aloe vera, which heals, reduces pain, and moisturises. For hundreds of years, it has healed skin burns and injuries. Aim: This study aims on the pharmaceutical assessment of Aloe-vera by formulating an herbal Body lotion. Material and Method: Aloe-vera, Honey, Glycerin, Rose Water and Triethanolamine were taken for the formulation of herbal body lotion. Evaluation parameters were also performed to evaluate the formulation and to make sure that the subjected formulation is not harmful for the human mankind. Result: The aloe vera body lotion was formulated by using various type of ingredients such as Aloe-vera, glycerin, rose water, honey and Triethanolamine. Aloe-vera contain antimicrobial and hydrating properties protect skin against microbial degradation and moisture to skin. Conclusion: herbal body lotion is prepared for tropical administration. Aloe vera is used in lotion to provide synergistic effect as well as moisturizing effect on skin. Herbal remedies are experiencing a surge in popularity worldwide. The utilization of aloe vera, honey, Coconut oil, Lemon Oil and glycerin in the formulation of an herbal lotion is an exemplary notion.","PeriodicalId":484171,"journal":{"name":"International Journal of Pharmacy and Pharmaceutical Science","volume":"139 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135446537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pharmacognostical and pharmacological study of Agave attenuata leaves","authors":"Praveen Kumar Chandra, Shaily Mishra","doi":"10.33545/26647222.2023.v5.i2a.44","DOIUrl":"https://doi.org/10.33545/26647222.2023.v5.i2a.44","url":null,"abstract":"The objective of the current study was to investigate several biological functions of an Agave attenuata leaf methanol extract. There were 25 chemicals identified by GC-MS in the n-hexane fraction of the extract, with mono-2-ethylhexyl phthalate (10.31%), 1, 2-benzenedicarboxylic acid (5.03%), n-docosane (5.45%), and eicosane (5.04%) serving as the main constituents. The total phenolic content in the leaves was 11.521-39.35 GAE mg/100 g, while the total flavonoid content was 42.35-304.8 CE mg/100g. Moderate antibacterial properties were seen in the extract and several of its components. By measuring DPPH radical scavenging activity and inhibiting lipid peroxidation experiments, leaf extract and fractions also showed good antioxidant ability. Hemolytic effects of the plant were found to range from 2.01% to 3.50%. This plant shows potential as a source of natural antioxidants and functional food nutraceuticals, according to the study's findings.","PeriodicalId":484171,"journal":{"name":"International Journal of Pharmacy and Pharmaceutical Science","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135102146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Formulation, evaluation and characterization of climbazole gel for the treatment of fungal infection","authors":"Shiva Sirohi, Mohd. Mujahid","doi":"10.33545/26647222.2023.v5.i2a.40","DOIUrl":"https://doi.org/10.33545/26647222.2023.v5.i2a.40","url":null,"abstract":"","PeriodicalId":484171,"journal":{"name":"International Journal of Pharmacy and Pharmaceutical Science","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135358070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dency Davis, Glen Loui Raphy, Grace Mariya, Rekha Paily, Bincy T Abraham
{"title":"Assessment of prescribing trends and risk of antiviral drugs in inpatients of tertiary care hospital","authors":"Dency Davis, Glen Loui Raphy, Grace Mariya, Rekha Paily, Bincy T Abraham","doi":"10.33545/26647222.2023.v5.i2a.43","DOIUrl":"https://doi.org/10.33545/26647222.2023.v5.i2a.43","url":null,"abstract":"Antiviral agents are crucial for managing viral infections, serving various roles, from prevention to treatment. Understanding their prescription patterns and risks is vital for optimizing clinical use. This study aims to observe prescription patterns and assess risks associated with antiviral drugs among inpatients at a tertiary care hospital. Objectives include evaluating prescription patterns across departments, identifying commonly prescribed antivirals, and monitoring associated risks. A prospective observational study was conducted over six months at a 450-bed tertiary care hospital. Inpatients receiving one or more antiviral drugs were included; ICU and outpatient cases were excluded. Medical records from over 100 patients were evaluated, with prescription trends and risk data recorded in a standard form. Data analysis utilizes graphical methods. The study found that 52% of participants were female, with most in the 61-70 and >80 age groups. Oseltamivir was the most frequently prescribed antiviral (56.5%), predominantly in the general medicine department (47.8%). Antivirals were commonly prescribed for lower respiratory tract infections (38.3%) in capsule form (35.6%). Most prescriptions were for lower respiratory tract infections in the general department (47.8%), including COVID-19 cases. No significant drug interactions were detected. Based on analysis of 115 prescriptions, this study revealed Oseltamivir as the most commonly prescribed antiviral, mainly for lower respiratory tract infections. Antiviral drugs were deemed safe for treatment, with no significant risks identified. The research underscored common antiviral use among the geriatric population. Overall, this study provides insights into prescription trends and risk assessment, enhancing understanding and safe use of antiviral agents in a tertiary care hospital.","PeriodicalId":484171,"journal":{"name":"International Journal of Pharmacy and Pharmaceutical Science","volume":"98 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136306842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}