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Cutback management strategies and citizen evaluation of government 削减管理策略与政府公民评价
IF 3.5 2区 管理学
Public Administration Pub Date : 2023-06-30 DOI: 10.1111/padm.12947
Carla Flink, Xiaoyang Xu
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引用次数: 1
Shaping influence in governance networks: The role of motivations and information exchange 治理网络的影响塑造:动机和信息交换的作用
IF 3.5 2区 管理学
Public Administration Pub Date : 2023-06-21 DOI: 10.1111/padm.12942
J. Reyes-Gonzalez, F. Agneessens, M. Esteve
{"title":"Shaping influence in governance networks: The role of motivations and information exchange","authors":"J. Reyes-Gonzalez, F. Agneessens, M. Esteve","doi":"10.1111/padm.12942","DOIUrl":"https://doi.org/10.1111/padm.12942","url":null,"abstract":"","PeriodicalId":48284,"journal":{"name":"Public Administration","volume":"43 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2023-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63553512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"管理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What motivates users to report service‐related issues? A study on coproduction in a smart public service 是什么促使用户报告与服务相关的问题？智能公共服务中的协同生产研究
IF 3.5 2区 管理学
Public Administration Pub Date : 2023-06-21 DOI: 10.1111/padm.12946
A. P. Rodriguez Müller, Amandine Lerusse, T. Steen, S. Van de Walle
{"title":"What motivates users to report service‐related issues? A study on coproduction in a smart public service","authors":"A. P. Rodriguez Müller, Amandine Lerusse, T. Steen, S. Van de Walle","doi":"10.1111/padm.12946","DOIUrl":"https://doi.org/10.1111/padm.12946","url":null,"abstract":"","PeriodicalId":48284,"journal":{"name":"Public Administration","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2023-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49074609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"管理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Co-treatment of Naringenin and Ketoprofen-RGD Suppresses Cell Proliferation via Calmodulin/PDE/cAMP/PKA Axis Pathway in Leukemia and Ovarian Cancer Cells. 柚皮苷和酮洛芬-RGD 共同作用可通过钙调蛋白/PDE/cAMP/PKA 轴通路抑制白血病和卵巢癌细胞的增殖
IF 1.6 2区 管理学
Public Administration Pub Date : 2023-06-19 eCollection Date: 2023-01-01 DOI: 10.5812/ijpr-136131
Havva Afshari, Shokoofe Noori, Bahareh Shokri, Afshin Zarghi
{"title":"Co-treatment of Naringenin and Ketoprofen-RGD Suppresses Cell Proliferation via Calmodulin/PDE/cAMP/PKA Axis Pathway in Leukemia and Ovarian Cancer Cells.","authors":"Havva Afshari, Shokoofe Noori, Bahareh Shokri, Afshin Zarghi","doi":"10.5812/ijpr-136131","DOIUrl":"10.5812/ijpr-136131","url":null,"abstract":"<p><strong>Background: </strong>Naringenin (Nar) has anti-inflammatory and anticarcinogenic properties. Arginine-glycine- aspartate (RGD) is a tripeptidic sequence used as an integrin ligand and targeting system for delivering chemotherapeutic agents to cancer cells.</p><p><strong>Objectives: </strong>In this study, the inhibitory effects of Nar and ketoprofen-RGD on leukemia and ovarian cancer cells (K562 and SKOV3) were explored for the first time, focusing on their proliferation activity and their anti-inflammatory capacity.</p><p><strong>Methods: </strong>Analyses were conducted on the calmodulin (CaM)-dependent phosphodiesterase 1 (PDE1) activation by ketoprofen-RGD, Nar, and their combination. These drugs' effects on protein kinase A (PKA) activation, intracellular cyclic adenosine monophosphate (cAMP) level, and PDE1 inhibition were identified. Later, it was also evaluated if ketoprofen-RGD alone or in combination with Nar had anti-inflammatory effects.</p><p><strong>Results: </strong>Nar improved the antagonizing consequences of ketoprofen-RGD on the CaM protein, which hinders PDE1, improving PKA activity and cAMP levels. A mixture of ketoprofen-RGD and Nar and ketoprofen-RGD alone diminished K562 and SKOV3 cell viability through the cAMP/PKA pathway by inhibiting PDE1 and CaM. These two compounds showed anti-inflammatory effects on both cell lines.</p><p><strong>Conclusions: </strong>This study indicated for the first time that combining ketoprofen-RGD and Nar can be a promising anti-inflammatory therapeutic regimen for treating leukemia and ovarian cancer.</p>","PeriodicalId":48284,"journal":{"name":"Public Administration","volume":"95 1","pages":"e136131"},"PeriodicalIF":1.6,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10728835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86432016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"管理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What does the evidence tell us about merit principles and government performance? 关于功绩原则和政府绩效，证据告诉我们什么？
IF 3.5 2区 管理学
Public Administration Pub Date : 2023-06-13 DOI: 10.1111/padm.12945
Eloy H. S. Oliveira, Gordon Abner, Shinwoo Lee, Kohei Suzuki, Hyunkang Hur, J. Perry
{"title":"What does the evidence tell us about merit principles and government performance?","authors":"Eloy H. S. Oliveira, Gordon Abner, Shinwoo Lee, Kohei Suzuki, Hyunkang Hur, J. Perry","doi":"10.1111/padm.12945","DOIUrl":"https://doi.org/10.1111/padm.12945","url":null,"abstract":"","PeriodicalId":48284,"journal":{"name":"Public Administration","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42354756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"管理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Permanently provisional: An ethnographic analysis of responsive governance practices in and through meetings 永久临时性：对会议中和通过会议采取的回应性治理做法的民族志分析
IF 3.5 2区 管理学
Public Administration Pub Date : 2023-06-12 DOI: 10.1111/padm.12943
E. Visser
{"title":"Permanently provisional: An ethnographic analysis of responsive governance practices in and through meetings","authors":"E. Visser","doi":"10.1111/padm.12943","DOIUrl":"https://doi.org/10.1111/padm.12943","url":null,"abstract":"","PeriodicalId":48284,"journal":{"name":"Public Administration","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2023-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42231788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"管理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Buying green in U.S. local government: Internal commitment and responsiveness to external pressures 在美国地方政府购买绿色产品：内部承诺和对外部压力的反应
IF 3.5 2区 管理学
Public Administration Pub Date : 2023-06-06 DOI: 10.1111/padm.12944
A. Dimand, M. Neshkova
{"title":"Buying green in U.S. local government: Internal commitment and responsiveness to external pressures","authors":"A. Dimand, M. Neshkova","doi":"10.1111/padm.12944","DOIUrl":"https://doi.org/10.1111/padm.12944","url":null,"abstract":"","PeriodicalId":48284,"journal":{"name":"Public Administration","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2023-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43718014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"管理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Seeing the nudge from the trees: The 4S framework for evaluating nudges 从树中看到轻推:评估轻推的4S框架
IF 3.5 2区 管理学
Public Administration Pub Date : 2023-05-30 DOI: 10.1111/padm.12941
Stuart Mills, R. Whittle
{"title":"Seeing the nudge from the trees: The 4S framework for evaluating nudges","authors":"Stuart Mills, R. Whittle","doi":"10.1111/padm.12941","DOIUrl":"https://doi.org/10.1111/padm.12941","url":null,"abstract":"","PeriodicalId":48284,"journal":{"name":"Public Administration","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49230136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"管理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Unpacking hybridity: Development and first validation of a multidimensional instrument to profile hybrid professionals 拆解混杂:开发和首次验证的多维工具，以分析混合专业人士
2区 管理学
Public Administration Pub Date : 2023-05-29 DOI: 10.1111/padm.12938
Amelia Compagni, Paola Roberta Boscolo, Giorgio Giacomelli, Marco Sartirana
{"title":"Unpacking hybridity: Development and first validation of a multidimensional instrument to profile hybrid professionals","authors":"Amelia Compagni, Paola Roberta Boscolo, Giorgio Giacomelli, Marco Sartirana","doi":"10.1111/padm.12938","DOIUrl":"https://doi.org/10.1111/padm.12938","url":null,"abstract":"Abstract Hybrid professionals, that is, professionals who have transitioned to managerial roles, have emerged in numerous public settings. Through in‐depth qualitative methodologies, the literature has shown a good degree of heterogeneity in the way hybrid professionals perceive and manage their hybridity. In this study, we aim to develop a theory‐based, multidimensional instrument able to capture such heterogeneity in a lean but sensitive way. In this instrument, we combine consolidated scales of identity centrality and integration and vignettes, on the one hand, to measure the perception of hybrid professionals of the relationship between their professional and managerial identities and, on the other hand, to elicit the practices they use to deal with the demands of the professional and managerial logics. We first validate the instrument on a sample of school principals in the Italian context and then describe the six profiles of hybrid professionals derived from the analysis. We suggest three avenues for applying such an instrument.","PeriodicalId":48284,"journal":{"name":"Public Administration","volume":"222 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135831789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"管理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Creating a public service topology: Mapping public service motivation, public service ethos, and public service values 创建公共服务拓扑:映射公共服务动机、公共服务精神和公共服务价值
IF 3.5 2区 管理学
Public Administration Pub Date : 2023-05-23 DOI: 10.1111/padm.12939
Eva M. Witesman, Lawrence C. Walters, R. Christensen
{"title":"Creating a public service topology: Mapping public service motivation, public service ethos, and public service values","authors":"Eva M. Witesman, Lawrence C. Walters, R. Christensen","doi":"10.1111/padm.12939","DOIUrl":"https://doi.org/10.1111/padm.12939","url":null,"abstract":"","PeriodicalId":48284,"journal":{"name":"Public Administration","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48940757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"管理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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