Michael Walsh, Kate Parker, Sue Crengle, Karen Bartholomew
{"title":"Projecting the future burden of lung cancer in Aotearoa New Zealand: informing screening implementation through regional and ethnic projections to 2045.","authors":"Michael Walsh, Kate Parker, Sue Crengle, Karen Bartholomew","doi":"10.26635/6965.7311","DOIUrl":"https://doi.org/10.26635/6965.7311","url":null,"abstract":"<p><strong>Aim: </strong>Lung cancer is the leading cause of cancer-related death in Aotearoa New Zealand and a major contributor to health inequities, particularly among Māori and Pacific peoples. Despite declines in smoking prevalence, lung cancer incidence remains high. Detailed projections are needed to inform future cancer service planning and support cancer control strategies.</p><p><strong>Methods: </strong>An age-period-cohort Poisson regression model was fitted to national cancer registry data (2001-2022), stratified by sex, prioritised ethnicity, age group and Health New Zealand - Te Whatu Ora region. Time-based weighting and non-parametric bootstrapping were used to derive projections and uncertainty intervals to 2045.</p><p><strong>Results: </strong>Annual lung cancer cases are projected to increase by 38.3%, from 2,544 in 2020-2022 to 3,519 in 2045 (95% uncertainty interval [UI] 3,275-3,771), despite a decline in the age-standardised rate from 28.2 to 23.6 per 100,000 (95% UI 21.6-25.7). Substantial ethnic inequities persist. Māori cases are projected to rise from 570 to 1,063 (an 86.5% increase), and Pacific cases from 129 to 245 (an 89.9% increase). Although rates are projected to fall across all groups, Māori are expected to continue to experience the highest rates. Regional variation is also evident, with the Northern Region projected to experience the largest increase in case numbers, from 872 to 1,280 by 2045.</p><p><strong>Conclusion: </strong>Although age-standardised incidence rates are expected to decline, rising case numbers indicate growing demand for diagnostic and treatment services. These projections support the need for equitable implementation of lung cancer screening and sustained investment in culturally responsive prevention and cessation support.</p>","PeriodicalId":48086,"journal":{"name":"NEW ZEALAND MEDICAL JOURNAL","volume":"139 1633","pages":"23-37"},"PeriodicalIF":1.3,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gemma Aburn, Tess Moeke-Maxwell, Merryn Gott, Ross Drake, Deborah Raphael
{"title":"Te Whare Kaiao-an Indigenous-informed paediatric palliative care framework for Aotearoa New Zealand.","authors":"Gemma Aburn, Tess Moeke-Maxwell, Merryn Gott, Ross Drake, Deborah Raphael","doi":"10.26635/6965.7271","DOIUrl":"https://doi.org/10.26635/6965.7271","url":null,"abstract":"<p><strong>Aim: </strong>This paper describes the development of an Indigenous-informed paediatric palliative care framework for Aotearoa New Zealand. Te Whare Kaiao (the living whare) builds upon the foundational framework of Te Whare Tapa Whā, recognising the core components integral to the delivery of quality paediatric palliative care.</p><p><strong>Methods: </strong>Te Whare Kaiao was developed in partnership with health professionals, whānau/lived experience experts and the Te Ārai Kahui kaumātua, using Kaupapa Māori community participatory research principles.</p><p><strong>Results: </strong>We identified the importance of highlighting that paediatric palliative care is about supporting children to live and reach their full potential. This is reflected in the symbolism used to depict Te Whare Kaiao.</p><p><strong>Conclusion: </strong>Te Whare Kaiao will be utilised in multiple different ways to inform clinical care delivery, empower communities and support research in children's palliative care within Aotearoa.</p>","PeriodicalId":48086,"journal":{"name":"NEW ZEALAND MEDICAL JOURNAL","volume":"139 1633","pages":"12-22"},"PeriodicalIF":1.3,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Appendicitis in disguise: a case of de Garengeot hernia.","authors":"Amy Van der Sluis, Khaleel Hamdulay","doi":"10.26635/6965.7270","DOIUrl":"https://doi.org/10.26635/6965.7270","url":null,"abstract":"","PeriodicalId":48086,"journal":{"name":"NEW ZEALAND MEDICAL JOURNAL","volume":"139 1633","pages":"112-115"},"PeriodicalIF":1.3,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ian C Shaw, Ashleigh R Woollett, Natasha M Dickie, Madison J Kennedy, Jacob T Liddle, Leila Bm Nolan, Megan Rawlins
{"title":"Is it safe to vape? Assessing the carcinogenic risk of \"vape smoke\".","authors":"Ian C Shaw, Ashleigh R Woollett, Natasha M Dickie, Madison J Kennedy, Jacob T Liddle, Leila Bm Nolan, Megan Rawlins","doi":"10.26635/6965.7434","DOIUrl":"https://doi.org/10.26635/6965.7434","url":null,"abstract":"<p><p>Vaping was introduced as a means of quitting smoking by slowly reducing nicotine dose to wean smokers of their carcinogenic habit. In this setting the risks of vaping likely outweigh the benefits of eliminating the carcinogenic risk associated with smoking cigarettes. Soon after the introduction of vaping it caught on as a trendy alternative to smoking, particularly among young people. This means that the risk-benefit profile changed considerably because the benefit of smoking cessation was no longer part of the risk-benefit equation. Since vaping has now become a primary means of taking nicotine, a risk assessment of vaping per se is necessary to determine its potential effects on vapers' health. In this viewpoint, we use our knowledge of the chemistry of the production of \"vape smoke\" to identify its key toxic components. Then, using published animal toxicity data for these chemicals and estimates of vapers' exposure levels, we assess the magnitude of carcinogenic risk. We conclude that vaping is carcinogenic, but that the risk is likely lower than for smoking cigarettes. Therefore, someone taking up vaping not as a tool for smoking cessation is adding carcinogenic risk to their daily risk profile.</p>","PeriodicalId":48086,"journal":{"name":"NEW ZEALAND MEDICAL JOURNAL","volume":"139 1633","pages":"104-111"},"PeriodicalIF":1.3,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cameron Schauer, Marius van Rijnsoever, Susan Taylor, Michael Tm Wang, Russell Walmsley, Jonathan Koea, Stephen Inns, Tom Hills
{"title":"The burden of secondary antibiotic resistance in Helicobacter pylori in Auckland, Aotearoa New Zealand.","authors":"Cameron Schauer, Marius van Rijnsoever, Susan Taylor, Michael Tm Wang, Russell Walmsley, Jonathan Koea, Stephen Inns, Tom Hills","doi":"10.26635/6965.7351","DOIUrl":"https://doi.org/10.26635/6965.7351","url":null,"abstract":"<p><strong>Aim: </strong>Helicobacter pylori (H. pylori) infection is the principle modifiable risk factor for gastric cancer and a key driver of ethnic disparities in gastric disease within Aotearoa New Zealand. Increasing antibiotic resistance threatens eradication success, yet secondary resistance patterns have not previously been described in New Zealand. This study aimed to describe, for the first time, secondary H. pylori antibiotic resistance rates in New Zealand and identify demographic predictors to inform eradication strategies.</p><p><strong>Methods: </strong>A retrospective review was conducted of H. pylori isolates referred for antibiotic susceptibility testing in Auckland between January 2018 and December 2023. Testing was performed at Middlemore Hospital Laboratory using gradient diffusion minimum inhibitory concentration (MIC) strips for amoxicillin, clarithromycin, metronidazole and tetracycline. Demographic data were obtained from the Auckland TestSafe database and analysed using univariate and multivariable logistic regression.</p><p><strong>Results: </strong>Of 3,234 patients tested, 644 (20%) were culture positive. Resistance rates were clarithromycin 68%, metronidazole 68.5%, amoxicillin 2.5% and tetracycline 0%. Male sex was associated with lower odds of metronidazole resistance (p<0.001). Māori and Pacific peoples had lower odds of both metronidazole and clarithromycin resistance compared with Europeans (p<0.05), while Asian ethnicity was associated with higher clarithromycin resistance (p=0.02).</p><p><strong>Conclusion: </strong>This first-in-New Zealand description of secondary H. pylori resistance shows high rates of clarithromycin and metronidazole resistance. These findings lend support to use of non-clarithromycin-based salvage regimens. Future prospective studies of secondary and also, most importantly, primary resistance data are essential to inform testing and treatment guidelines and improve eradication outcomes.</p>","PeriodicalId":48086,"journal":{"name":"NEW ZEALAND MEDICAL JOURNAL","volume":"139 1633","pages":"55-64"},"PeriodicalIF":1.3,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natalie Allen, Akilesh Gokul, Jie Zhang, Micah Rapata, Rachael Niederer, Charles McGhee
{"title":"Barriers to eye donation in Aotearoa New Zealand: a novel qualitative analysis.","authors":"Natalie Allen, Akilesh Gokul, Jie Zhang, Micah Rapata, Rachael Niederer, Charles McGhee","doi":"10.26635/6965.7234","DOIUrl":"https://doi.org/10.26635/6965.7234","url":null,"abstract":"<p><strong>Aim: </strong>Aotearoa New Zealand has experienced declining eye donation rates despite high levels of corneal disease and strong capacity to perform corneal transplantation. Demand for donor corneal tissue far exceeds supply. This study explored public attitudes toward eye donation, which have not previously been evaluated in New Zealand.</p><p><strong>Method: </strong>Ten semi-structured focus groups were conducted, recorded and transcribed. Participant opinions were analysed using saturation and sentiment approaches. Transcripts were manually coded in NVivo15, with iterative thematic analysis until saturation was achieved.</p><p><strong>Results: </strong>A total of 44 participants were interviewed. Overall sentiment toward eye donation was positive, with 40 (90%) supporting donation for themselves or family. Barriers to donation included poor awareness (42, 96%), cultural considerations (41, 93%), feelings of disgust (23, 52%) and religious beliefs (13, 30%). Among Māori and Pacific participants (16, 44%), the absence of established tikanga (customary values/practices) around eye donation emerged as a key theme. Baseline knowledge was low: only 13 (30%) had prior awareness, and just two (5%) understood New Zealand's donation infrastructure.</p><p><strong>Conclusion: </strong>Most focus group participants supported eye donation; however, poor awareness, cultural uncertainty and limited infrastructure remain barriers. New Zealand has the population and capacity to achieve self-sufficiency, but system-level changes are needed to improve eye donation rates.</p>","PeriodicalId":48086,"journal":{"name":"NEW ZEALAND MEDICAL JOURNAL","volume":"139 1632","pages":"71-81"},"PeriodicalIF":1.3,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147521879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clots without a cause: a case of large asymptomatic pacemaker lead-associated thrombi.","authors":"Annie Ho, Michael Dick, Ivor Gerber","doi":"10.26635/6965.7236","DOIUrl":"https://doi.org/10.26635/6965.7236","url":null,"abstract":"","PeriodicalId":48086,"journal":{"name":"NEW ZEALAND MEDICAL JOURNAL","volume":"139 1632","pages":"106-110"},"PeriodicalIF":1.3,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147521995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vartika Sharma, Parvinca Saini, Isabelle Uy, Julia Vajda De Albuquerque, Sarah Hetrick, Roshini Peiris-John, Rodrigo Ramalho
{"title":"Invisible struggles, urgent priorities: mental health of ethnic migrant women and girls in Aotearoa New Zealand.","authors":"Vartika Sharma, Parvinca Saini, Isabelle Uy, Julia Vajda De Albuquerque, Sarah Hetrick, Roshini Peiris-John, Rodrigo Ramalho","doi":"10.26635/6965.7220","DOIUrl":"https://doi.org/10.26635/6965.7220","url":null,"abstract":"<p><strong>Aim: </strong>Ethnic communities in Aotearoa New Zealand are rapidly growing and highly diverse. Migration-related experiences are deeply gendered, shaping health and wellbeing in distinct ways. This multi-methods research study aimed to understand the mental health needs of ethnic migrant women and girls, and to highlight opportunities for culturally responsive support by co-designing a research agenda with high-priority research questions.</p><p><strong>Methods: </strong>In-depth interviews were conducted with 12 key stakeholders and analysed using thematic analysis. Insights informed a subsequent stakeholder consultation workshop, facilitated using a collaborative World Café approach to co-design research priorities.</p><p><strong>Results: </strong>Interview findings suggest nuanced contextual factors that affect mental health, lack of safe spaces including family networks, reluctance to engage with mental health services, and limited cultural responsiveness. The co-designed research priorities emphasise the importance of participatory approaches and evidence rooted in lived realities to inform services that are meaningful, culturally safe and responsive to ethnic women's needs.</p><p><strong>Conclusion: </strong>Ethnic women's mental health requires a nuanced culturally responsive approach. Through community engagement and co-design, this study identified unmet needs and set clear research priorities to inform meaningful, evidence-based support and care.</p>","PeriodicalId":48086,"journal":{"name":"NEW ZEALAND MEDICAL JOURNAL","volume":"139 1632","pages":"13-23"},"PeriodicalIF":1.3,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147522107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David G McNamara, Catherine A Byrnes, Angela J Campbell, Samuel Dalton, Oka Sanerivi, Tambra Trist
{"title":"New Zealand paediatric respiratory stock-take survey.","authors":"David G McNamara, Catherine A Byrnes, Angela J Campbell, Samuel Dalton, Oka Sanerivi, Tambra Trist","doi":"10.26635/6965.7183","DOIUrl":"10.26635/6965.7183","url":null,"abstract":"<p><strong>Aim: </strong>Tamariki (children) in Aotearoa New Zealand suffer high rates of respiratory morbidity. There are also geographic, socio-economic and ethnicity inequities, with tamariki Māori and Pacific children, experiencing the highest rates. Our aim was to survey New Zealand respiratory health services and identify gaps in delivery.</p><p><strong>Methods: </strong>We invited health practitioners from all districts to respond to an online survey and separately contacted individuals known to deliver paediatric respiratory care. We included medical, nursing and allied health staff and collated responses.</p><p><strong>Findings: </strong>There were 23 responses from 17 hospitals. Respiratory- and sleep-specialist senior medical officers (SMOs) were employed in only three major centres. Full time equivalent (FTE) for paediatricians with an interest (PWI) in respiratory care was evenly distributed with low numbers reported in the Northern region, Wellington and Canterbury. Senior nurse FTE was fairly constant across the country, except in the Northern region. Allied health staffing was inconsistent across the country with many districts in the Te Manawa Taki region reporting little or no respiratory physiotherapy staffing. More than half of districts reported limited or no access to videofluoroscopic swallow studies. There is poor access to chest computed tomography (CT) scanning under general anaesthetic in more than half of centres.</p><p><strong>Conclusion: </strong>Despite high levels of respiratory disease and morbidity, with serious disparities, there is inadequate staffing and provision of services. There is an urgent need for better co-ordination of care but a lack of both national and regional frameworks despite respiratory health being a current health target.</p>","PeriodicalId":48086,"journal":{"name":"NEW ZEALAND MEDICAL JOURNAL","volume":"139 1632","pages":"114-119"},"PeriodicalIF":1.3,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147522017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Delirium incidence, risk factors and outcomes in a New Zealand tertiary intensive care unit: a retrospective, observational, single-centre study.","authors":"Joyce Ng, David Sidebotham, Anthony Williams","doi":"10.26635/6965.7147","DOIUrl":"https://doi.org/10.26635/6965.7147","url":null,"abstract":"<p><strong>Aim: </strong>Our aim was to determine the incidence of delirium in a tertiary intensive care unit (ICU) in Auckland, New Zealand compared to other Australasian ICUs. To determine the incidence of delirium among different ethnicities and identify risk factors and outcomes of patients experiencing delirium.</p><p><strong>Methods: </strong>The design was a retrospective observational study. The setting was a single-centre, 24 bed, tertiary ICU in Auckland, New Zealand. The participants were two hundred and twenty-two patients admitted to the ICU over 10 months in 2019. The main outcome measures were incidence of delirium, identified using the Confusion Assessment Method - ICU (CAM-ICU) screening, antipsychotic prescription, 12-month mortality, and ICU discharge disposition.</p><p><strong>Results: </strong>Fifty of the 222 (23%) patients had delirium. There was no association between the incidence of delirium and ethnicity (p=0.39). The risk of delirium increased with ICU duration of stay (odds ratio [OR]: 1.003, 95% CI, 1.001-1.005, p=0.004), days on vasopressors (p<0.001) and days on mechanical ventilation (p<0.001). Thirty-three of the 50 (66%) patients received at least one antipsychotic medication. Twelve-month mortality was not associated with delirium (OR: 0.97, 95% CI 0.73-1.22, p=0.81). Delirium was not associated with ICU discharge disposition (p=0.20).</p><p><strong>Conclusions: </strong>The incidence of delirium in this single-centre, tertiary Auckland ICU was comparable to other Australasian ICUs. There was no difference in the incidence of delirium between different ethnicities. Positive associations to delirium included length of stay in ICU, number of days on vasopressors and duration of mechanical ventilation. Delirium was not associated with an increased risk of 12-month mortality and was not associated with ICU discharge disposition.</p>","PeriodicalId":48086,"journal":{"name":"NEW ZEALAND MEDICAL JOURNAL","volume":"139 1632","pages":"92-100"},"PeriodicalIF":1.3,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147522080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}