Middle East Research Journal of Medical Sciences最新文献

{"title":"The Correlation of HbA1c with Serum Electrolytes among Type 2 Diabetic Patients in Atbara, River Nile State, Sudan","authors":"Khalda Sid Ahmed M. Seed, S. Noor, G. M. Mahjaf, M. Hamad","doi":"10.36348/merjms.2024.v04i04.002","DOIUrl":"https://doi.org/10.36348/merjms.2024.v04i04.002","url":null,"abstract":"Background: Diabetes mellitus in Sudan is a growing health problem that is associated with poor glycemic control in all socio-economic classes. This is a study that was conducted in Naserldeen Karamalla diabetic center located at Atabara River Nile state. Aims: The study aimed to evaluate the relationship between glycated hemoglobin (HbA1c) and serum electrolytes in type 2 diabetic patients. Methods: The present study was a Cross-sectional, descriptive hospital-based study. A total of 500 type 2 diabetics with ages ranging from 15 to 87 years volunteered to participate in this study. The glycated hemoglobin (HbA1c), and serum electrolyte & were measured with standard procedure. The statistical analysis was done by using SPSS version 20. Results: The mean HbA1c was 10.8±6.6 %. (96.6%) of the patients who had poor glycemic control (HbA1c >60.5) the mean Mg, Ca, Na, K, and Cl was 2.06±0.68, 9.1 ±3.7, 140.9 ±7.0, 3.9 ±0.41 and101.04 ±7.7 respectively. In this study, the correlation between Mg+2 and HbA1c was statistically insignificant (P. value =0.765) and between Ca 2+ and HbA1c was statistically insignificant (P. value = 0.586). Insignificant correlation between Na+ and HbA1c P value = 0.283). An inverse relation between HbA1C and K+ (P. value = 0.020). Conclusion: HbA1c and serum potassium were negatively correlated while sodium, calcium, magnesium, and chloride had an insignificant correlation.","PeriodicalId":478944,"journal":{"name":"Middle East Research Journal of Medical Sciences","volume":"99 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141681857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sero-Detection of Coxiella Burnett (Q fever) Infection Anti-Antibodies Igg and Igm among Spontaneous, Recurrent Miscarriage Women in Gezira State, Sudan -Case-Control Studies 2018","authors":"Shimaa Sharaf Eldin Mohamed Abbas, Mogahid Yaguob Abdegadir Ahmed, Abdamalik Hassab elrsoul Abdamalik, Ahmed Jdeed Essa Suliman, Ali Ahmed Ali Yousef, Ali Omer Mohammed Abdudafea, A. A. Osman, Mosab N","doi":"10.36348/merjms.2024.v04i04.001","DOIUrl":"https://doi.org/10.36348/merjms.2024.v04i04.001","url":null,"abstract":"Background: Q fever is a zoonosis caused by the bacterium Coxiella burnetii and is associated with epizootic abortion in ungulates. In humans, the role of Q fever during pregnancy has been recently questioned. Objectives: Thus, the goal of this study was to investigate the seroprevalence of C. Burnett infection among pregnant women in Gezira state, Sudan as well as the relationship between spontaneous recurrent abortion and pregnancy. Methods: This study included 90 women, half of whom had recurrent spontaneous abortion (RSA) and the other half had successful pregnancies. Blood samples were taken simply randomly, with ethical considerations, and using open ended closed questionnaire, prepared samples, and kept at -20°C. The seroprevalence of IgG and IgM antibodies against C. burnetti was determined using a commercial enzyme-linked immunosorbent assay test kit. Means of frequencies plus standard error, Chi2, and in depending sample t-test and logistic regression univariate and multivariate tests have been used. Result: The overall prevalence of C. burnetii in the study population sera was (37/90) 41.11 percent, with 5(11.1%) and 11(24.4 %) positive miscarriages in pregnant women for C. Burnetti IgM and IgG, respectively. While in nonmiscarriage were 8 (17.8 %) and 13 (28.9 %) positive for IgM (OR .578, CI-95% .174-1.926, P .372), and IgG (OR .796, CI-95% .312-2.032, P .634), respectively. Other significant risk factors detected in the study were age(OR 5, CI-95% 2-13, P 0.001), biomax index (OR 5, CI-95% 2-12, P 0.001), Diabetic patients (OR 11,1CI-95% 11 -11.38 P 0.000), disorder of thyroid (OR 8,9 CI-95% 8.1 -9 P 0.000), microcytic hypochromic anemia (OR 11, CI-95% 1.1 -110.2 P 0.04), Menstruation Cycle (OR 3.8, CI-95% 1.2 -11.5, P 0.02), vaginal bleeding(OR 6.4 CI-95% 2.1-19.2, P 0.001), pre-eclampsia(OR 16.1, CI-95% 1.9-131.1, P 0.01), and miscarriage family history(OR 2.9, CI-95% 2.8 -9.8, P 0.000), RDWC(OR 4.4, CI-95% 1.8 -10.9, P 0.002), RDWSD (OR 19.2 CI-95% 5.2 -71.1, P 0.000). Conclusion: The study concluded that the seroprevalence of Coxiella burnetii among miscarriage and nonpregnant women in Gezira State was dissociation with miscarriage. While selection risk factors associated with miscarriage include age, biomaxindex, Diabetic patients, a disorder of the thyroid, menstruation Cycle, vaginal bleeding, pre-eclampsia, miscarriage family history, microcytic hypochromic anemia, RDWC, and RDWSD.","PeriodicalId":478944,"journal":{"name":"Middle East Research Journal of Medical Sciences","volume":"96 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141686973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How Are Short-Chain Fatty Acids Associated with Deranged Lipid Profiles in Cad Patients?","authors":"Anil Batta","doi":"10.36348/merjms.2024.v04i01.006","DOIUrl":"https://doi.org/10.36348/merjms.2024.v04i01.006","url":null,"abstract":"Background: The phenomenon of Coronary Slow Flow (CSF) is an angiographic clinical verity, which is characterized by late opacification of the distal segments of the coronary artery without having significant stenosis. However, a definite and reliable mechanism of CSF is still not known. Short-chain fatty acids (SCFA) such as acetate, butyrate, and propionate are produced as a result of the fermentation of indigestible dietary fibres in the gut by the microbiota. Many studies have investigated the role of SCFA as a related signalling pathway in inflammation, glucose metabolism, and lipid metabolism. In this study, we investigated the correlation between Short Chain Fatty Acids and Lipid Profile serum in Patients with Slow Flow Coroner. Materials and Methods: 50 patients who were referred to the Department of Internal Medicine, Muzaffarnagar Medical College, Muzaffarnagar, were selected based on inclusion and exclusion criteria. Data was obtained through laboratory examination and stool samples. Stool samples were analyzed for SCFA (acetate, propionate, and butyrate acids) with gas chromatography. Results: The results of the present study indicate that SCFA, acetate, propionate, and valerate did not show a significant correlation with lipid profile (P>0.05). The level of fecal butyrate was negatively correlated with HDL (p=<0.05; r = -0.532). Conclusions: Our study indicated that the level of butyrate was a moderate negative correlated with HDL inpatient with slow flow coroner.","PeriodicalId":478944,"journal":{"name":"Middle East Research Journal of Medical Sciences","volume":"178 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140459521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Sudden Sit-Stand Postural Switch on Electroencephalogram","authors":"M. Adeniyi, Awosika Ayoola, Anna Chika Idaguko","doi":"10.36348/merjms.2024.v04i01.005","DOIUrl":"https://doi.org/10.36348/merjms.2024.v04i01.005","url":null,"abstract":"Postural changes are inevitable motor behavior and physiological phenomenon. The study recorded electroencephalographic findings characterizing sudden switch from sitting to standing posture. 15 young adult males who satisfied inclusion criteria were recruited for the study. Baseline electroencephalographic tracings were obtained using Powerlab 26T at sitting position using scalp electrodes and during sudden switch from sitting to standing. The results of the study revealed sudden switch from sitting had no significant effect on alpha wave amplitude, beta wave amplitude and beta wave frequency. However, both alpha wave frequency and alpha/beta ratio decreased with sudden switch from sitting to standing position. The findings of the study indicated that sudden sitting to standing posture caused reductions in alpha wave and alpha/beta ratio.","PeriodicalId":478944,"journal":{"name":"Middle East Research Journal of Medical Sciences","volume":"40 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140460983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Walking Pace Induced Cardiovascular Recovery in School Sport- Aversive Students: Role of Gender","authors":"M. Adeniyi, Anna Chika Idaguko","doi":"10.36348/merjms.2024.v04i01.004","DOIUrl":"https://doi.org/10.36348/merjms.2024.v04i01.004","url":null,"abstract":"The importance of School sporting activities on psychomotor, cognitive and overall health of students has been documented. The aim of the study was to investigate the gender influence of walking pace on cardiovascular recovery in school sport aversive students. 30 students that consisted of 16 males and 14 females were recruited for the study using respondent driven sampling out of a pool of 50 students after satisfying the inclusion criteria. They were made to walk through the treadmill at 2.7km/h (low walking pace), 4.4 km/h (medium walking pace) and 5.5km/h (high walking pace) for 3 minutes. Blood pressure, pulse rate and SP02 were measured before, immediately after and 1 minute post recovery. High walking pace induced recovery systolic blood pressure was significantly elevated in females when compared to male. Recovery diastolic blood pressure, recovery mean arterial blood pressure (MABP), recovery pulse pressure and recovery pulse rate were higher at high walking pace in females than males. Under high, medium and low walking paces, shock index and pulse rate were elevated in females than males. In conclusion, school sport aversive females showed lower cardiovascular recovery than their male counterparts.","PeriodicalId":478944,"journal":{"name":"Middle East Research Journal of Medical Sciences","volume":"53 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139965327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Nocturnal Push-Up on Morning Values of Peripheral Oxygen Saturation and Cardiovascular Indices in Young Males","authors":"M. Adeniyi, Anna Chika Idaguko","doi":"10.36348/merjms.2024.v04i01.003","DOIUrl":"https://doi.org/10.36348/merjms.2024.v04i01.003","url":null,"abstract":"A typical physical exercise is characterized by intensity, frequency, duration and rhythmicity. The study investigated the effect of nocturnal push-up on morning values of peripheral oxygen saturation (SPO2) and cardiovascular indices in apparently healthy males who have neither participated in pushup nor any programmed physical activities in the past three months. 15 apparently healthy young males averaging 16 years executed pushup work-out (44reps/min) between 7pm and 9 pm for a period of 2 weeks. SPO2, blood pressure and pulse rate were measured early in the morning between 6am and 8am 1 week before commencement of workout, two weeks of workout and a week after cessation of workout. Morning values of blood pressure and pulse rate were not significantly affected by either two week of pushup or cessation. However, morning value of SPO2 was significantly increased following 2 weeks of nocturnal pushup. 1week following cessation, SPO2 was not significantly altered. The finding of the study showed the beneficial effect of nocturnal pushup on peripheral oxygen saturations in young males.","PeriodicalId":478944,"journal":{"name":"Middle East Research Journal of Medical Sciences","volume":"156 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140470212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of Immunity Status of Vaccinated Health Care Workers against Hepatitis B Virus in Khartoum State, Sudan","authors":"Leila Mohamed A. Abdelgader, Aisha M. ELmamoon Mohammed, G. M. Mahjaf, Tibyan Abd Almajed Altaher, M. Hamad","doi":"10.36348/merjms.2024.v04i01.002","DOIUrl":"https://doi.org/10.36348/merjms.2024.v04i01.002","url":null,"abstract":"Background: The vaccination of health care workers (HCWs) for the hepatitis B virus (HBV) is a crucial part of hospital infection control programs. They are considered to be a population at high risk of developing HBV infection due to the high transmissibility of the virus and the risk related to occupational injuries. The risk is particularly high in HCWs with greater exposure to accidental inoculation at work and is related to the duration of professional activity, the characteristics of the healthcare center, and the type of population served. Objectives: The current study was conducted to evaluate the immunity status of the vaccinated HCWs against HBV in Khartoum State. Materials and Methods: This cross-sectional descriptive laboratory-based study was conducted from December 2022 to February 2023. Data were collected through a structured questionnaire regarding age, gender, type of employment, length of employment, and duration of vaccination for each participant. 90 vaccinated HCWs were enrolled in this study; serum samples were collected from each participant; the Enzyme Linked Immuno Sorbent Assay technique was used to detect the anti-HBs level; and the collected data were analyzed using Statistical Package for the Social Sciences (SPSS). Results: This study included 90 healthcare workers, female 70 (77.8%), male 20 (22.2%) ages ranging from 20 to 52 years old, 45 (50%) of them laboratory specialists, and 23 (23.3%). Nursing 17 (18.9%), Dentists 5 (5.6%), and 2.5 (2.2%). The results of the current study reveal that 70% of the studied vaccinated HCWs have a protective level of HBs-Ab. Of these, 23.3% had an anti-HBs titer between 10 and 100 mIU/ml, and the rest, 46.7%, had an anti-HBs titer >100 mIU/ml, while 30% of them were not protective, 22.2% of them were males, and the rest, 77.8%, were females, with a mean age of 30 years. Conclusion: Though many HCWs had been exposed to the virus before or had received vaccinations, the majority of them were seroprotected against the hepatitis B virus. HCWs must be made aware of the prescribed immunization schedule and must be required to receive all recommended vaccinations.","PeriodicalId":478944,"journal":{"name":"Middle East Research Journal of Medical Sciences","volume":"44 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140510530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Age on Semen Parameters of Northern Sudanese Couples","authors":"Mohammed Ahmed Ibrahim Ahmed, M. Elkarsany, Nahla Ahmed Mohamed Abderahman, Elameen Elawad Ali, M. Hamad","doi":"10.36348/merjms.2024.v04i01.001","DOIUrl":"https://doi.org/10.36348/merjms.2024.v04i01.001","url":null,"abstract":"Background: There are several physiological changes brought on by the inevitable process of aging. For exploring the potential role of aging in male infertility; we examined the semen quality in Northern Sudanese sub fertile men. Objectives: This study aimed to look into possible association between male age and different sperm parameters derived from semen analysis taking into account the World Health Organization (WHO) reference values of semen indicators. Methods: A retrospective descriptive study included 150 Northern Sudanese Couples men presenting with primary or secondary infertility who underwent semen analysis at Modern Specialized Laboratory (MSL), Atbara, River Nile State, Sudan, between August 2021 and April 2023. Seminal fluid were collected in a sterile, wide mouth container, by dry masturbation, after at least 48 hours of abstinence and brought immediately to the laboratory. Color, viscosity, PH and volume were examined macroscopically, and motility under the microscope within 20 minutes to one hour of collection time and was stained by10% Giemsa stain after fixation by spirit for 10-15min. Morphology and abnormal sperms were checked manually to assess the abnormalities in the head, midpiece and the tail of the sperm. This manual method was allowed the discrimination of immature sperm from white blood cells (WBCs) and then counting the WBCs. Data were collected by predesigned closed ended questionnaires, through direct personal interview with patients and questionnaires were filled after an informed consent was taken from each patient. The statistical analysis was done with the help of statistical software for social sciences SPSS 21. The characteristics of the semen, personal and demographic data were analyzed according to the standard protocols. Results: There was significant positive association between age and the different measured parameters except for the reaction and presence of microorganism and, a significant difference was found with the presence of microorganism by p=0.004. Conclusion: Age differences between participants were not observed to have an impact on semen parameters.","PeriodicalId":478944,"journal":{"name":"Middle East Research Journal of Medical Sciences","volume":"60 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140512351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}