International journal of pharmaceutical and bio-medical science最新文献

Association of Iron Profile with Type 2 Diabetes Mellitus:Review 铁概况与 2 型糖尿病的关系：综述

International journal of pharmaceutical and bio-medical science Pub Date : 2024-03-21 DOI: 10.47191/ijpbms/v4-i3-13

Khaldoon Jasim Mohammed, Salam Kitab Rubat, Ahmed Falah Imran

引用次数: 0

Investigation of an Antifouling Compound from Sponge Siphonodictyon coralliphagum 海绵 Siphonodictyon coralliphagum 防污化合物研究

International journal of pharmaceutical and bio-medical science Pub Date : 2024-03-18 DOI: 10.47191/ijpbms/v4-i3-08

Robert. A. Bara, Fitje Losung, Calvyn F. A. Sondak, Jimmy Posangi, Remus Maradou, Stefan Kehraus

{"title":"Investigation of an Antifouling Compound from Sponge Siphonodictyon coralliphagum","authors":"Robert. A. Bara, Fitje Losung, Calvyn F. A. Sondak, Jimmy Posangi, Remus Maradou, Stefan Kehraus","doi":"10.47191/ijpbms/v4-i3-08","DOIUrl":"https://doi.org/10.47191/ijpbms/v4-i3-08","url":null,"abstract":"Marine fouling is attaching organisms to objects floating or submerged in seashores, such as ships, docks, and offshore structures. The impact caused is the reduced lifespan of the thing attached to the biofouling. In addition, there was a spread of invasive species. The government and industries in the United States spend over 6.5 million dollars annually on their budget to overcome this problem. So far, the prevention of marine biofouling is using antifouling paint on ships and submerged structures. One of them is organotin tributyltin (TBT) proven effective for preventing fouling; however, it is not environmentally friendly. Sponge Siphonodictyon coralliphagum growing in Salibabu Island waters, Talaud Islands, with previously shown activities against prokaryotes, was collected and extracted by maceration using ethanol as a solvent. The extract was then added to the base paint with several compositions of 5%, 10%, and 25% applied to the paving block surface. Positive control uses paint with copper additives. The objects are then immersed in the seashore below subtidal depths. The observation was carried out every seven days until day 28. The paving block was observed on day 90 after immersion. Significant results were obtained where macrofouling was only able to grow in negative control and positive control. The extract sponge S. coralliphagum has vigorous antifouling activity against marine biofouling. Furthermore, the extract was fractionated using liquid chromatography and continued by testing their activity against Gram-positive and negative bacteria. Further investigation of NMR spectra from the active fraction to prokaryotic cells shows a cyclic aliphatic compound with several keto-enol functional and methyl aliphatic groups on their chain.","PeriodicalId":475981,"journal":{"name":"International journal of pharmaceutical and bio-medical science","volume":"313 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140233087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quality of Life of Parents and Patients with Biliary Atresia in Native Liver 原肝胆道闭锁患者的父母和患者的生活质量

International journal of pharmaceutical and bio-medical science Pub Date : 2024-03-18 DOI: 10.47191/ijpbms/v4-i3-07

Jeannie Flynn, R. Prihaningtyas, Syania Mega Octariyandra, Anindya Kusuma Winahyu, Bagus Setyoboedi, Mira Irmawati, S. Arief

{"title":"Quality of Life of Parents and Patients with Biliary Atresia in Native Liver","authors":"Jeannie Flynn, R. Prihaningtyas, Syania Mega Octariyandra, Anindya Kusuma Winahyu, Bagus Setyoboedi, Mira Irmawati, S. Arief","doi":"10.47191/ijpbms/v4-i3-07","DOIUrl":"https://doi.org/10.47191/ijpbms/v4-i3-07","url":null,"abstract":"Children with chronic conditions such as biliary atresia may experience several issues that affect their quality of life (QoL). Childhood chronic disease impacts family members and leads to family health impairment. Objective: This study aims to asses the QoL of parents and patients with biliary atresia. Methods and material: The assessment of parent and patient quality of life with biliary atresia was conducted using the Pediatric Quality of Life (PedsQL) parent report and the World Health Organization Quality of Life (WHOQoL).Multivariate linear regression was used for associated factors. This case-control study involved 38 children (0-24 months) with biliary atresia at the Dr. Soetomo General Academic Hospital Surabaya, which was conducted from June to July 2023. Data obtained showed that male and female prevalence was equal (50%). Age <6 months, mothers with high school education, family income >3 million rupiahs, normal nutritional status were frequently in patients with biliary atresia. Based on the WHOQoL questionnaire, the environment was the only domain that impacted the quality of life of the parents significantly (P= 0.005). However, no significant association with patients' QoL was found for the five domains of the PedsQL. The environment factor had a significant impact on the QoL of the patient's parents according to the results of the WHOQoL questionnaire (P= 0.005).","PeriodicalId":475981,"journal":{"name":"International journal of pharmaceutical and bio-medical science","volume":"42 37","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140231410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectivity of Irrigation Solution from Stevia rebaudiana Bertoni Leaf Extract on the Growth of Enterococcus faecalis Bacteries 甜叶菊叶提取物灌溉液对粪肠球菌菌群生长的影响

International journal of pharmaceutical and bio-medical science Pub Date : 2024-03-18 DOI: 10.47191/ijpbms/v4-i3-09

S. Deviyanti, Silva Abraham, B. Pasiga

{"title":"Effectivity of Irrigation Solution from Stevia rebaudiana Bertoni Leaf Extract on the Growth of Enterococcus faecalis Bacteries","authors":"S. Deviyanti, Silva Abraham, B. Pasiga","doi":"10.47191/ijpbms/v4-i3-09","DOIUrl":"https://doi.org/10.47191/ijpbms/v4-i3-09","url":null,"abstract":"Disinfection of Enterococcus faecalis bacteria in dental root canal treatment using NaOCL 0.5-2.5% is still a challenge. There is still very little data on the effectvity of Stevia rebaudiana Bertoni leaf extract irrigation solution against the growth of Enterococcus faecalis. This study evaluated the effectiveness of Stevia rebaudiana Bertoni leaf extract irrigation solution against Enterococcus faecalis ATCC 29212 through MIC (Minimal Inhibitory Concentration) and MBC (Minimal Bactericide Concentration) values. A number of 100 µl of E. faecalis suspension was inoculated into 96 microtitration wells, each containing 100 µl of 100%, 50%, 25%, 12.5%, 6.25%, 3.125%, 1.56% of Stevia leaf extract irrigation solutions, positive (NaOCL 2.5%) and negative (distilled water) control. Incubation was carried out for 24 hours at 37°C then optical density was measured with a microplate reader at 600 nm. Five µl of 10-9 dilution of each group was dripped and spread onto nutrients agar plate. The number of Enterococcus faecalis colonies was counting manually. There was no significant difference in average colony count of Enterococcus faecalis between the 100% and 50% Stevia leaf extract irrigation solution groups and the positive control (p>0.05). However, the 25%, 12.5%, 6.25%, 3.125%, and 1.56% Stevia leaf extract irrigation solution groups showed significant differences (p<0.05). Stevia leaf extract irrigation solution suppressed growth at MIC 6.25% by turbidimetry and MIC 1.56% by total plate count method using nutrient agar and than killed Enterococcus faecalis at MBC 50%. The bactericidal ability of 100% and 50% Stevia leaf extract irrigation solution is equal to NaOCL 2.5%.","PeriodicalId":475981,"journal":{"name":"International journal of pharmaceutical and bio-medical science","volume":"79 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140234134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of Factors of Low Grades and Academic Failure of Medical Students 识别医学生成绩低下和学业失败的因素

International journal of pharmaceutical and bio-medical science Pub Date : 2024-03-16 DOI: 10.47191/ijpbms/v4-i3-12

Dr. Alaa Mufaq Musleh

{"title":"Identification of Factors of Low Grades and Academic Failure of Medical Students","authors":"Dr. Alaa Mufaq Musleh","doi":"10.47191/ijpbms/v4-i3-12","DOIUrl":"https://doi.org/10.47191/ijpbms/v4-i3-12","url":null,"abstract":"Background: Students are human capital and future of all countries, several factors affect students’ academic status leading to academic burnout and possibly academic failure, academic failure can delay finding a job and lead to frustration, loss of morale, and ultimately result in a large cost. Several factors may lead to academic failure, such as age, gender, scientific background, motivation and interest in the field, marital status, occupation status, place of residence, parental employment and education level, financial ability and others. Academic failure of students is not a personal problem, but rather a social issue; therefore, fundamental steps must be taken toward addressing the issue. Aim: The aim of study to Determine academic failure and related factors among medical students of Tikrit university college of medicine. Subject and methods: The current study is cross section study type was carried out in medical students from 21th of November 2022 to the 5th of March 2023.The study design was by convenient sampling, from medical students .The Exclusion criteria of participants was all students with a good academic level, while all other students were included in the study.The data was collected using Google form Questinaire. Results: The total samples of study was (202), the bad time management is the most factors affecting on students with low grades (93%), work while studying (49%), family responsibility (25%), Psychological problems (10.4%), pathological problems (6%), Low economic state (5.4%). the students with second trial had highest bad time management (35.4%), work while studying (25.8%). The poor teaching quality is the highest percentage (50%) of evaluation, moderate (32%), good (14%), (4%) excellent. the students satisfaction with effective teaching methods is moderate (44%), poor (36%), good (17%) and excellent (3%). Conclusions: The bad time management is the most factors affecting on students with low grades.","PeriodicalId":475981,"journal":{"name":"International journal of pharmaceutical and bio-medical science","volume":"134 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140235786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Uncommon Tumor in Stomach in A Young Girl 少女胃部的罕见肿瘤

International journal of pharmaceutical and bio-medical science Pub Date : 2024-03-16 DOI: 10.47191/ijpbms/v4-i3-11

M. Mukhopadhyay, Rituparna Kayal, Subhamoy Saha, Malobika Baisya, Binata Bandopadhyay, B. Mukhopadhyay

{"title":"An Uncommon Tumor in Stomach in A Young Girl","authors":"M. Mukhopadhyay, Rituparna Kayal, Subhamoy Saha, Malobika Baisya, Binata Bandopadhyay, B. Mukhopadhyay","doi":"10.47191/ijpbms/v4-i3-11","DOIUrl":"https://doi.org/10.47191/ijpbms/v4-i3-11","url":null,"abstract":"Introduction: Gastrointestinal stromal tumours (GIST) are rare tumours of the Gastrointestinal tract. They are the most common mesenchymal tumour of the gastrointestinal tract. All GISTs are malignant.Among all Gastrointestinal tract malignancies GIST Comprises 0.1- 3%. The most common location is stomach. They are usually found in elderly and they are not common in pediatric age group. Case Report: A girl aged 16 years presented with the history of melena, hematemesis with dyspepsia. Physical examination revealed mild tenderness over right hypochondrium. On examination, multiple hypopigmented patches noted over both upper limbs. CECT abdomen showed a well-defined heterogeneously enhancing predominantly exophytic necrotic soft tissue SOL over the greater curvature of the proximal body of the stomach with intraluminal extension. Her complete blood count and routine biochemical tests were within normal limits. Endoscopic biopsy from the polyploid lesion along the greater curvature show fragmented bits of gastric mucosa involved by a tumour composed of sheets and fascicles of round to oval cells having eosinophilic to vacuolated cytoplasm and a few spindle cells. Histopathological examination revealed a mesenchymal neoplasm favouring GIST.. Then wide local excision of the stomach was done and sent for histopathological examination. The stomach mass was diagnosed as Epithelioid GIST which was confirmed by immunohistochemistry. Conclusion: GISTs are most common mesenchymal tumours of GI tract. They are malignant in nature. The primary treatment of choice is surgery followed by chemotherapy.","PeriodicalId":475981,"journal":{"name":"International journal of pharmaceutical and bio-medical science","volume":"125 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140235671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biological Roles of Chitinase 1 in Pathogenic Conditions 几丁质酶 1 在致病条件下的生物学作用

International journal of pharmaceutical and bio-medical science Pub Date : 2024-03-16 DOI: 10.47191/ijpbms/v4-i3-10

Ahmed Abdulkadhim Hamidy, Marwah A.K. Hameedi, Noor Ali Abdul Jabbar

{"title":"Biological Roles of Chitinase 1 in Pathogenic Conditions","authors":"Ahmed Abdulkadhim Hamidy, Marwah A.K. Hameedi, Noor Ali Abdul Jabbar","doi":"10.47191/ijpbms/v4-i3-10","DOIUrl":"https://doi.org/10.47191/ijpbms/v4-i3-10","url":null,"abstract":"Chitin is a prevalent biopolymer found in arthropods such as mollusks, crustaceans, nematodes, worms, and insects. Chitin do not consider as a structural component in mammals. Chitinase enzymes are a group of proteins that have a special ability to attach to and break down chitin, and they are widely preserved throughout evolution. Chitinase in humans was first identified by its ability to break down chitotrioside which is considered as its substrates and for that reason it named chitotriosidase which is also known as CHIT1 or chitinase-1. It is primarily secreted from macrophages during their activated phase in both typical and inflammatory circumstances. Individuals with Gaucher's disease (GD) have a notable rise in CHIT1 activity in both plasma and tissues compared to those without the condition. GD is a hereditary ailment characterized by lipid buildup in certain organs’ macrophages such as the lungs, spleen, liver, kidneys, bone marrow, and brain. Serum CHIT1 levels are commonly utilized as a robust diagnostic biomarker to assess the effectiveness of therapy for several diseases that we reviewed in this review.","PeriodicalId":475981,"journal":{"name":"International journal of pharmaceutical and bio-medical science","volume":"108 s1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140236143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Some Ecological Factors on Stomata and Phenolic Compounds Production in Aloe Vera L. Gel and Effect Gel to the Adult of Flour Beetle: Tribolium Castaneum (Coleoptera : Tenebriodae) 一些生态因素对芦荟凝胶中气孔和酚类化合物产生的影响以及凝胶对面粉甲虫成虫的影响：Tribolium Castaneum (Coleoptera : Tenebriodae)

International journal of pharmaceutical and bio-medical science Pub Date : 2024-03-07 DOI: 10.47191/ijpbms/v4-i3-05

Mwafaq Inhab Salih Al-Hamdany, Mohammad Adnan Hashem Alblesh, Huda Damin Abduljabbar Al-Tikrity

{"title":"Effect of Some Ecological Factors on Stomata and Phenolic Compounds Production in Aloe Vera L. Gel and Effect Gel to the Adult of Flour Beetle: Tribolium Castaneum (Coleoptera : Tenebriodae)","authors":"Mwafaq Inhab Salih Al-Hamdany, Mohammad Adnan Hashem Alblesh, Huda Damin Abduljabbar Al-Tikrity","doi":"10.47191/ijpbms/v4-i3-05","DOIUrl":"https://doi.org/10.47191/ijpbms/v4-i3-05","url":null,"abstract":"This search presents the effect of some ecological factors such as (ultraviolet –B radiation , temperature , salinity ) on stomatal index and stomatal frequency and phenolic compounds after exposure to Aloe vera L. UV-B radiation , temperature and salinity . Ultraviolet – B radiation is one of the important abiotic factors that can stimulate the production of secondary metabolites, including phenolic compounds. Aloe vera (Asphodelaceae) is a medicinal plant used in Iraq for treating sunburn, wounds, and heartburn. The flour beetle: Tribolium castaneum is one of the inset causes of loss storage food yield in the world. The study aims the effect of some ecological factors such as (ultraviolet –B radiation , temperature , salinity ) on stomatal index and stomatal frequency and phenolic compounds after exposure to Aloe vera L. UV-B radiation , temperature and salinity and investigate the insecticidal and repellency effect of leaf gel for Aloe vera to estimate the percentage of the insecticidal effect for concentrations 25, 50, 75, and 100 % of alcoholic extract within seven days on adult insects. The gel in leaf exposure to UV-B radiation contained a higher diversity of phenolic compounds and flavonoids. This search showed a high percent kill for an adult with 100% of the alcoholic extract compared with control and an excellent effect of Aloe vera gel at a concentration of 50 % for a repellency effect with a value of 10.842%. Phenolic compounds showed after exposure to UV as : (dioxyflavone ,kampferol, catechuic acid, flavonol glucuronic acid, gabardine isoflavone, isoquercitrin, p-coumaric acid, hispaglabridine ) with a high percentage in the gel after exposure to UV-B compared by control.","PeriodicalId":475981,"journal":{"name":"International journal of pharmaceutical and bio-medical science","volume":"156 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140260633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative Study between Bilateral and Unilateral Erector Spinae Plane Block in Managing Postoperative Pain in Laparoscopic Cholecystectomy 双侧和单侧脊束肌平面阻滞在处理腹腔镜胆囊切除术术后疼痛中的比较研究

International journal of pharmaceutical and bio-medical science Pub Date : 2024-03-07 DOI: 10.47191/ijpbms/v4-i3-06

Dr. Ali Shawqi Sadoon, Dr. Anwar Abd Alabbas Hlail, Dr. Maysoon Ali Abdulkareem

{"title":"Comparative Study between Bilateral and Unilateral Erector Spinae Plane Block in Managing Postoperative Pain in Laparoscopic Cholecystectomy","authors":"Dr. Ali Shawqi Sadoon, Dr. Anwar Abd Alabbas Hlail, Dr. Maysoon Ali Abdulkareem","doi":"10.47191/ijpbms/v4-i3-06","DOIUrl":"https://doi.org/10.47191/ijpbms/v4-i3-06","url":null,"abstract":"Background: Postoperative pain after laparoscopic cholecystectomy remains as an important problem, with two components: somatic and visceral. Surgical incisions lead to somatic pain, while abdominal inflation and diaphragm irritation leads to visceral pain. Erector spinae plane block is a newly described interfascial plane block. Aim: to compare bilateral versus unilateral erector spinae plane block for postoperative analgesia in laparoscopic cholecystectomy Patients and Methods: The study involved 50 patients scheduled for elective laparoscopic cholecystectomy. Patients were randomly assigned in to two equal groups each with 25 patients: unilateral and bilateral erector spinae plane block. Numerical Pain score and need for analgesia during all time points to 12 hr post recovery; hemodynamic indices at baseline, during all time poins from full recovery to 12 hr post recovery were recored. Results: there were no significant differences between the two groups in hemodynamic indices. At 12thhr post operation, 36%, 12% and 36% of patients in unilateral group demonstrated mild, moderate and required rescue analgesia, respectively compared with 28%, 8% and 20% of patients in bilateral group with a statistically significant difference. at 3rdhr post operation, 12% and 8% of patients in unilateral group need paracetamol and tramal, respectively, compared 4% and 0%, respectively in bilateral group, with a significant difference. Additionally, at 12thhr post operation, 34% and 12% of patients in unilateral group need paracetamol and tramal, respectively, compared 28% and 8%, respectively in bilateral group, with a significant difference. Conclusions: Unilateral and bilateral erector spinae plane block seem to have no serious impact hemodynamic indices. Bilateral block is associated with lower pain score and need for postoperative analgesia than unilateral block","PeriodicalId":475981,"journal":{"name":"International journal of pharmaceutical and bio-medical science","volume":"6 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140260110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New Horizons in Understanding and Developing Treatments for Human Reproductive Physiology 了解和开发人类生殖生理学疗法的新视野

International journal of pharmaceutical and bio-medical science Pub Date : 2024-03-04 DOI: 10.47191/ijpbms/v4-i3-02

Hala Read Megibl

{"title":"New Horizons in Understanding and Developing Treatments for Human Reproductive Physiology","authors":"Hala Read Megibl","doi":"10.47191/ijpbms/v4-i3-02","DOIUrl":"https://doi.org/10.47191/ijpbms/v4-i3-02","url":null,"abstract":"This comprehensive review delves into the cutting-edge advancements and emerging trends in the field of human reproductive physiology. It aims to shed light on the intricate processes governing human reproduction and the novel therapeutic approaches being developed to address various reproductive health issues. The review begins with a detailed exploration of the fundamental aspects of human reproductive systems, including hormonal regulation, gametogenesis, and the genetic underpinnings of reproductive functions. Significant attention is given to recent breakthroughs in treating infertility, highlighting new findings in both male and female reproductive health. The review discusses the evolution and current state of assisted reproductive technologies (ART), such as IVF, and their increasingly successful application in overcoming infertility. Furthermore, it explores the potential of personalized medicine in tailoring treatments to individual reproductive disorders, considering genetic, environmental, and lifestyle factors. Innovations in contraceptive technologies and their implications for reproductive health management are also examined. The review extends into the realm of reproductive genetics, emphasizing how genomic studies have enhanced our understanding of reproductive disorders and congenital anomalies. Ethical, social, and legal considerations surrounding the latest reproductive technologies are critically analyzed, recognizing the complex interplay between scientific advancements and societal norms. The review concludes by identifying future research directions, underscoring the importance of interdisciplinary approaches in advancing our understanding and treatment of human reproductive physiology. This article serves as a vital resource for researchers, clinicians, and policymakers, offering a comprehensive overview of the current landscape and future prospects in human reproductive health and medicine.","PeriodicalId":475981,"journal":{"name":"International journal of pharmaceutical and bio-medical science","volume":"72 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140266354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0