Krystal D Eskildsen, Hildemar Dos Santos, Ernesto Medina, Dixon Anjejo, W Lawrence Beeson
{"title":"The Association Between Non-exercise Activity Thermogenesis and Diabetes Status in U.S. Adults: NHANES 2013-2014.","authors":"Krystal D Eskildsen, Hildemar Dos Santos, Ernesto Medina, Dixon Anjejo, W Lawrence Beeson","doi":"10.1177/15598276261450525","DOIUrl":"10.1177/15598276261450525","url":null,"abstract":"<p><p>Non-exercise activity thermogenesis (NEAT), the energy expended through daily unstructured movement, may influence type 2 diabetes (T2D) risk but is rarely emphasized in diabetes care. Few studies have examined NEAT-diabetes associations using nationally representative data. We conducted a cross-sectional analysis of 4436 U.S. adults aged ≥18 years from NHANES 2013-2014 with ≥4 days of valid wrist accelerometer wear. Daily movement was quantified using Monitor-Independent Movement Summary (MIMS) units as a proxy for NEAT and categorized as low, moderate, or high. Multivariable logistic regression estimated adjusted odds ratios (ORs) for T2D across NEAT levels, controlling for key demographic and socioeconomic factors. Stratified models examined racial and ethnic differences. Low NEAT was associated with nearly threefold higher odds of diabetes compared with high NEAT (OR = 2.88). Moderate NEAT also showed elevated odds (OR = 1.61). Associations were significant among Hispanic, non-Hispanic White, and non-Hispanic Asian adults and marginal among non-Hispanic Black adults. Lower NEAT levels are strongly associated with higher odds of diabetes, highlighting NEAT as an accessible behavior that may support equitable diabetes prevention and management.</p>","PeriodicalId":47480,"journal":{"name":"American Journal of Lifestyle Medicine","volume":" ","pages":"15598276261450525"},"PeriodicalIF":1.9,"publicationDate":"2026-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13229904/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148165158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Grace Taiwo Otitoju, Joseph Benitez, Shekeel Ahmed, Jennifer Molokwu, Alok Kumar Dwivedi
{"title":"Interrelationship Between Depression, Unhealthy Behavior, and Non-Alcoholic Fatty Liver Disease in the United States of America.","authors":"Grace Taiwo Otitoju, Joseph Benitez, Shekeel Ahmed, Jennifer Molokwu, Alok Kumar Dwivedi","doi":"10.1177/15598276261449749","DOIUrl":"https://doi.org/10.1177/15598276261449749","url":null,"abstract":"<p><p>Non-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease globally, with increasing prevalence among adults. Despite its growing burden, limited research has examined the influence of psychosocial factors, including unhealthy behavior on NAFLD in the USA. Retrospective cross-sectional study was conducted using data from the 2013-2018 National Health and Nutrition Examination Survey. Descriptive statistics, stratified prevalence estimates, and Poisson regression models were used to assess unadjusted and adjusted associations. The results showed that among 5804 eligible participants, the overall prevalence of NAFLD was 42%. Higher prevalence was observed among males (48%), individuals with obesity (37%), those reporting unhealthy behaviors (48%), and those with depressive disorders (47%). In adjusted models, unhealthy behavior (PR = 1.35; 95% CI: 1.22-1.49; <i>P</i> < 0.001) and depression (PR = 1.13; 95% CI: 1.04-1.22; <i>P</i> = 0.005) were independently associated with an increased prevalence of NAFLD among young US adults and is independently associated with modifiable behavioral and psychological factors. These findings underscore the need for integrated public health strategies as well as nutritional interventions that could address lifestyle behaviors and mental health to mitigate the burden of NAFLD in this population.</p>","PeriodicalId":47480,"journal":{"name":"American Journal of Lifestyle Medicine","volume":" ","pages":"15598276261449749"},"PeriodicalIF":1.3,"publicationDate":"2026-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13223074/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148151622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"\"Health Equity-Driven Lifestyle Medicine: Essential Lessons for Every Lifestyle Medicine Provider\" - Highlights from the LM2025 Conference Session.","authors":"Qadira Ali, Faith Nyong, David Bowman","doi":"10.1177/15598276261449773","DOIUrl":"https://doi.org/10.1177/15598276261449773","url":null,"abstract":"<p><p>Health equity remains a central yet insufficiently integrated priority within lifestyle medicine (LM). Although LM offers evidence-based strategies to prevent and treat chronic disease, its impact is limited when interventions fail to account for the social determinants of health (SDOH) shaping patient behavior and access. Despite growing appreciation of the importance of screening for and addressing social drivers of health, knowledge, skills, and resource gaps remain for many LM practitioners. This innovation report synthesizes key insights from the LM2025 conference session and translates them into a practical, equity-centered framework. We propose a three-domain model emphasizing (1) prioritization of populations experiencing health disparities, (2) context-sensitive application of lifestyle interventions, and (3) delivery of culturally relevant, community-engaged care. We illustrate application through a pediatric case and highlight the Family Lifestyle Program Produce Prescription (FLiPRx) as a scalable model of health equity-driven LM. We further examine biological pathways linking social adversity to chronic disease and describe how lifestyle interventions mitigate these effects. Additionally, we highlight a multisector collaboration between a hospital, health department and churches as a model for achieving health equity. This framework offers clinicians and health systems a practical pathway to integrate equity into LM practice while advancing population health outcomes.</p>","PeriodicalId":47480,"journal":{"name":"American Journal of Lifestyle Medicine","volume":" ","pages":"15598276261449773"},"PeriodicalIF":1.3,"publicationDate":"2026-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13223072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148151609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Democratization Dilemma: What CMMI Adoption Means for Lifestyle Medicine Certification.","authors":"Padmaja Patel","doi":"10.1177/15598276261453308","DOIUrl":"https://doi.org/10.1177/15598276261453308","url":null,"abstract":"","PeriodicalId":47480,"journal":{"name":"American Journal of Lifestyle Medicine","volume":" ","pages":"15598276261453308"},"PeriodicalIF":1.3,"publicationDate":"2026-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13223067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148151567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"AI in Lifestyle Medicine.","authors":"David Michael, Michelle Thompson, Jasdeep Saluja","doi":"10.1177/15598276261449784","DOIUrl":"https://doi.org/10.1177/15598276261449784","url":null,"abstract":"<p><p>Artificial intelligence (AI) is rapidly transforming clinical medicine, yet its application in lifestyle medicine (LM) has only begun to be described systematically. This article synthesizes real-world experiences from three diverse clinical settings (a regional health system, a large academic medical center, and a lifestyle medicine specialty clinic) to illustrate how AI can optimize LM delivery while preserving the human connection at the heart of care. We describe the use of ambient AI scribes to reduce documentation burden and restore clinician-patient presence; AI-enabled analysis of structured lifestyle questionnaires and wearable data to personalize counseling and accountability; AI tools for rapid evidence retrieval; and generative AI to accelerate development of group medical visit curricula and patient education materials. Early outcomes include reduced documentation time, improved provider well-being, enhanced patient engagement, and the ability to scale high-touch LM interventions. We align these applications with the Quintuple Aim of better outcomes, lower cost, improved patient and provider experience, and health equity, and we outline practical steps, ethical considerations (including the environmental and community costs of AI infrastructure), and future directions for \"precision lifestyle medicine.\" When deployed responsibly, AI functions as a force multiplier that amplifies the reach and impact of lifestyle medicine clinicians.</p>","PeriodicalId":47480,"journal":{"name":"American Journal of Lifestyle Medicine","volume":" ","pages":"15598276261449784"},"PeriodicalIF":1.3,"publicationDate":"2026-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13222212/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148145052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Applying Lifestyle Medicine to Enhance Cancer Survivorship and Patient Well-being.","authors":"Jasmin Hundal, Madeline Hardacre, Amy Comander","doi":"10.1177/15598276261454630","DOIUrl":"https://doi.org/10.1177/15598276261454630","url":null,"abstract":"<p><p>Lifestyle medicine provides an evidence-based framework for addressing the complex and evolving needs of patients across the cancer continuum. Built on 6 pillars, physical activity, nutrition, sleep, stress management, social connectedness, and avoidance of risky behaviors, lifestyle medicine is supported by major organizations as a core component of comprehensive oncology care. Cancer therapies frequently disrupt dietary intake through treatment-related toxicities, while long-term survivorship is often complicated by metabolic dysfunction and weight change. Current guidance emphasizes whole food-based dietary patterns and limiting ultra-processed foods, red meat, and alcohol, although evidence for specific dietary strategies in recurrence prevention remains mixed. Regular physical activity improves quality of life, reduces treatment-related symptoms, and is associated with improved survival outcomes. Sleep disturbances, psychosocial stress, and social isolation are also prevalent and linked to immune dysregulation, inflammation, and worse clinical outcomes; evidence-based interventions such as cognitive behavioral therapy and mindfulness-based stress reduction can improve psychological and functional well-being. Tobacco and alcohol cessation remain critical priorities given their associations with treatment complications, recurrence, and mortality. Effective implementation requires coordinated, multidisciplinary care models that integrate behavioral health, rehabilitation, nutrition, and community resources. Embedding longitudinal, patient-centered lifestyle interventions into oncology practice may improve survivorship outcomes and overall health.</p>","PeriodicalId":47480,"journal":{"name":"American Journal of Lifestyle Medicine","volume":" ","pages":"15598276261454630"},"PeriodicalIF":1.3,"publicationDate":"2026-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13222219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148145091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nathaniel Woodard, Jingle Xu, Tara-Ann Perreault, Nathalie Lopez, Jamie L Conklin, Rebecca L Hoover, Rachel Hirschey
{"title":"A Systematic Review of Randomized Controlled Community-Based Physical Activity Trials for Adult Cancer Survivors.","authors":"Nathaniel Woodard, Jingle Xu, Tara-Ann Perreault, Nathalie Lopez, Jamie L Conklin, Rebecca L Hoover, Rachel Hirschey","doi":"10.1177/15598276261451750","DOIUrl":"https://doi.org/10.1177/15598276261451750","url":null,"abstract":"<p><p>The benefit of physical activity for those who have been diagnosed with cancer is well recognized. However, methods to promote long-term engagement in physical activity among survivors of cancer are less clear. Community-based interventions may promote survivors' long-term engagement in physical activity. The current systematic review synthesizes the effectiveness of randomized controlled trial-tested community-based physical activity interventions for adult cancer survivors, identifies characteristics of effective interventions, and reports on sustainability among these interventions. Systematic searches of three research databases were performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, identifying 14 reports for inclusion in the current review. Quality appraisal of included reports was assessed using the NIH Quality Assessment of Controlled Intervention Studies Tool. Overall, findings support the use of community-based interventions to promote physical activity among cancer survivors. However, opportunities exist to improve community-based trials, including consistent assessment of intervention sustainability, utilization of health behavior theory, objective measurement of behavior change, and tailored interventional components to further improve effectiveness. Further research on mechanisms underlying intervention effectiveness, sustainability, and approaches for high-risk and underserved populations is needed.</p>","PeriodicalId":47480,"journal":{"name":"American Journal of Lifestyle Medicine","volume":" ","pages":"15598276261451750"},"PeriodicalIF":1.3,"publicationDate":"2026-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13219120/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148139322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Curious Case of Midlife Wellness Medfluencers.","authors":"Mohammed Abrahim","doi":"10.1177/15598276261455280","DOIUrl":"10.1177/15598276261455280","url":null,"abstract":"<p><p>The rapid expansion of lifestyle medicine content on social media has fundamentally transformed the dissemination and consumption of health information. Among the most prominent contributors are physician influencers (\"medfluencers\"), who leverage professional credentials to communicate directly with public audiences. Within this evolving digital ecosystem, an under-recognized subgroup has emerged: physicians undergoing midlife or mid-career transitions who translate personal health transformations into publicly disseminated narratives. This Perspective introduces the concept of <i>Midlife Wellness Medfluencers</i> (MWMs) and critically examines its implications for evidence-based lifestyle medicine. Specifically, it explores the intersection of medical authority, autobiographical experience, and midlife transition within the amplifying context of social media. While experiential insights may serve as valuable sources of hypothesis generation, their increasing prominence raises important epistemological concerns. In particular, the conflation of personal narrative with generalizable scientific evidence risks undermining the principles of evidence-based practice.</p>","PeriodicalId":47480,"journal":{"name":"American Journal of Lifestyle Medicine","volume":" ","pages":"15598276261455280"},"PeriodicalIF":1.9,"publicationDate":"2026-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13219107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148139398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Resistance Training for Special Populations: A Universal, Clinically Safe, and Scalable Framework for Progressive Training.","authors":"Jeff Young, Andrew Mock","doi":"10.1177/15598276261454617","DOIUrl":"https://doi.org/10.1177/15598276261454617","url":null,"abstract":"<p><p>Resistance training is consistently underutilized and underdosed among individuals with chronic disease, musculoskeletal limitations, cancer survivorship, and aging-related decline. Although these groups are often assumed to require condition-specific programs, most present with multiple comorbidities, diverse stages of disease progression, and different symptom patterns. This article outlines a universal, clinically safe resistance training framework grounded in the same sequence used for all adults: screening, assessment, initiation through a structured familiarization phase, and ongoing progression via flexible linear and non-linear periodization. Auto-regulation and individualized modifications allow training to be tailored safely by inserting the appropriate medical or musculoskeletal precautions without changing the core structure of the program. This model improves confidence, reduces fear-based underdosing, and reliably develops the primary physiological adaptations, including strength, conditioning, power, and lean mass that drive improved function, metabolic health, resilience, and quality of life across populations and age groups.</p>","PeriodicalId":47480,"journal":{"name":"American Journal of Lifestyle Medicine","volume":" ","pages":"15598276261454617"},"PeriodicalIF":1.3,"publicationDate":"2026-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13219113/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148139406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lifestyle First and Lifestyle Always, Does Not Mean Lifestyle Only: Reimagining Cardiometabolic Care in the Era of GLP-1 Receptor Agonists.","authors":"Elizabeth Joy, Jonathan Bonnet","doi":"10.1177/15598276261450530","DOIUrl":"https://doi.org/10.1177/15598276261450530","url":null,"abstract":"<p><p>The rapid uptake of glucagon-like peptide-1 receptor agonists (GLP-1 RAs), including semaglutide and tirzepatide, has transformed the management of obesity, diabetes, and cardiometabolic disease, producing substantial weight loss, improved glycemic control, and reduced cardiovascular and renal risk. This article advances a guiding principle for contemporary care: \"lifestyle first and lifestyle always, but not lifestyle only.\" While GLP-1 RAs have reshaped clinical practice and reinforced recognition of obesity as a biologically mediated disease, pharmacotherapy alone cannot resolve the complex behavioral, physiologic, and social drivers of cardiometabolic risk. Discontinuation of GLP-1 RAs without structured lifestyle support commonly results in weight regain, and medication does not address sarcopenia, physical deconditioning, sleep, stress, psychosocial determinants, or social connection. Lifestyle behaviors, high-quality nutrition, regular physical activity including resistance training, restorative sleep, stress management, social connectedness, and a sense of purpose, constitute the physiological and behavioral foundation for durable health gains. GLP-1 RAs are therefore positioned not as substitutes for lifestyle change, but as catalysts that create metabolic and psychological conditions that are favorable to adopting and sustaining healthy behaviors. Integrated, interprofessional models that combine pharmacologic and lifestyle strategies, supported by policy and systems change, are proposed as the emerging standard for long-term cardiometabolic health.</p>","PeriodicalId":47480,"journal":{"name":"American Journal of Lifestyle Medicine","volume":" ","pages":"15598276261450530"},"PeriodicalIF":1.3,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13201374/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148044268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}