Oral and Maxillofacial Surgery-Heidelberg最新文献_第8页

Peripherally induced movement disorders in the stomatognathic system after oral surgical or dental procedures. 口腔外科或牙科手术后外周引起的口颌系统运动障碍。

IF 1.7

Oral and Maxillofacial Surgery-Heidelberg Pub Date : 2024-12-01 Epub Date: 2024-08-01 DOI: 10.1007/s10006-024-01285-4

Kazuya Yoshida

{"title":"Peripherally induced movement disorders in the stomatognathic system after oral surgical or dental procedures.","authors":"Kazuya Yoshida","doi":"10.1007/s10006-024-01285-4","DOIUrl":"10.1007/s10006-024-01285-4","url":null,"abstract":"Objectives: Peripherally induced movement disorders (PIMD) are hyperkinetic movement disorders that can occur after injury to a part of the body. This study aimed to identify PIMD in the stomatognathic system following dental or oral surgical procedures.Materials and methods: A total of 229 patients with PIMD (144 women and 85 men; mean age: 53.4 years) triggered by oral surgical or dental interventions were evaluated retrospectively.Results: The average latency between the procedures and onset of PIMD was 14.3 days. Oral surgery (40.2%), including tooth extraction, trauma treatment, and other surgical procedures, was the most frequent trigger of PIMD. This was followed by general dental treatment, including periodontal, endodontic, and restorative procedures (36.7%), prosthetic treatment (19.7%), and orthodontic treatment (3.5%). PIMD consisted of oromandibular dystonia (73.8%), functional (psychogenic) movement disorders (11.4%), orolingual dyskinesia (7.9%), and hemimasticatory spasms (5.7%).Conclusions: These results suggest that even minor alterations in normal anatomy or physiology after dental procedures may result in PIMD in predisposing patients.Clinical relevance: Dental professionals should be aware that although infrequently, PIMD can develop after various dental treatments. If such symptoms precipitate, the attending physician should properly explain them to the patient and provide appropriate treatment or consultation with a movement disorder specialist.","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":" ","pages":"1579-1586"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141861287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of tranexamic acid on intra- and postoperative bleeding in Bimaxillary osteotomies: a retrospective study. 氨甲环酸对双颌截骨术术中和术后出血的影响：一项回顾性研究。

IF 1.7

Oral and Maxillofacial Surgery-Heidelberg Pub Date : 2024-12-01 Epub Date: 2024-09-03 DOI: 10.1007/s10006-024-01288-1

Ayako Mizutani, Takuro Sanuki, Kanta Kido

{"title":"Effectiveness of tranexamic acid on intra- and postoperative bleeding in Bimaxillary osteotomies: a retrospective study.","authors":"Ayako Mizutani, Takuro Sanuki, Kanta Kido","doi":"10.1007/s10006-024-01288-1","DOIUrl":"10.1007/s10006-024-01288-1","url":null,"abstract":"Purpose: Perioperative bleeding is a serious concern during orthognathic surgery. Tranexamic acid (TXA), a synthetic lysine analog with antifibrinolytic properties, reduces blood loss across various surgical fields. This study aimed to investigate the effectiveness of preoperative TXA administration in reducing intraoperative and postoperative blood loss following combined Le Fort I and sagittal split ramus osteotomies at our hospital.Methods: This single-center, retrospective cohort study included patients who underwent combined Le Fort I and sagittal split ramus osteotomies between November 2017 and October 2022. The primary outcome was the volume of intraoperative blood loss.Results: Among 1,329 eligible patients, 87 were included in the analysis (32 in the TXA group and 55 in the control group, where no TXA was administered). The median (interquartile range) intraoperative blood loss was 200.0 (157.5-237.5) mL in the TXA group and 260.0 (180.0-350.0) mL in the control group, showing a significant difference between the groups (p = 0.0365). However, postoperative blood drainage within 24 h and 24-48 h did not differ significantly between the two groups.Conclusion: A single intravenous administration of TXA was associated with a decrease in intraoperative bleeding without severe adverse events during combined Le Fort I and sagittal split ramus osteotomies. However, postoperative blood loss, nausea, vomiting, and autologous blood transfusion were not significantly associated with this administration.","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":" ","pages":"1617-1622"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142120882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application and evaluation of carbonate apatite granules for mandibular bone defect reconstruction after jawbone cyst enucleation-a retrospective case series. 碳酸盐磷灰石颗粒在颌骨囊肿去核术后下颌骨缺损重建中的应用和评估--回顾性病例系列。

IF 1.7

Oral and Maxillofacial Surgery-Heidelberg Pub Date : 2024-11-22 DOI: 10.1007/s10006-024-01306-2

Naoyuki Fukuda, Natsumi Takamaru, Kazuya Akita, Keiko Kudoh, Kunio Ishikawa, Youji Miyamoto

{"title":"Application and evaluation of carbonate apatite granules for mandibular bone defect reconstruction after jawbone cyst enucleation-a retrospective case series.","authors":"Naoyuki Fukuda, Natsumi Takamaru, Kazuya Akita, Keiko Kudoh, Kunio Ishikawa, Youji Miyamoto","doi":"10.1007/s10006-024-01306-2","DOIUrl":"https://doi.org/10.1007/s10006-024-01306-2","url":null,"abstract":"Purpose: To evaluate the effectiveness of CO3Ap granules in the mandibular bone defects by using computed tomography (CT) images.Methods: This study was retrospective case series of mandibular bone defect reconstruction using CO3Ap granules. Six patients with jawbone cysts treated by simultaneous grafting CO3Ap granules after cyst enucleation were enrolled. Patients without grafting CO3Ap granules were excluded. Mandibular bone height including buccolingual bone height, the change of perpendicular distance between the buccolingual line to the alveolar ridge, and the three-dimensional volume of remaining CO3Ap granules were analyzed using CT images obtained at 3, 6, 12, 18, and 24 months postoperatively.Results: Postoperative CT images showed that cortical and cancellous bone-like structures were formed on the grafting area periphery and inside the defect, respectively, with gradual resorption of the CO3Ap granules. Furthermore, there was no evidence of leaving bone defect even at the center of the lesion when the defect was successfully reconstructed by filling it with CO3Ap granules. The percentage volume of remaining CO3Ap granules to the volume at 3 months postoperatively were 76.1 ± 13.1%, 35.8 ± 22.5%, 25.0 ± 13.0%, and 9.9 ± 6.4% at 6, 12, 18, and 24 months postoperatively, and the volume reduction rate increased significantly within 12 months postoperatively.Conclusion: Grafting CO3Ap granules after the enucleation of a jawbone cyst is a good reconstructive treatment option for postoperative prosthetic treatment because CO3Ap granules are gradually replaced by new bone while preserving the contour of the mandibular bone.Clinical trial number: Not applicable.","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":"29 1","pages":"14"},"PeriodicalIF":1.7,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142688910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Congenital teratoma of the oral cavity - the largest personal series of cases. 口腔先天性畸胎瘤--最大的个人病例系列。

IF 1.7

Oral and Maxillofacial Surgery-Heidelberg Pub Date : 2024-11-22 DOI: 10.1007/s10006-024-01307-1

Renato da Silva Freitas, Bruna Ferreira Bernert, Isis Juliane Guarezi Nasser, Fabiola Grigoletto Lupion, Eduardo Angeli-Freitas, Cesar Vinícius Grande

{"title":"Congenital teratoma of the oral cavity - the largest personal series of cases.","authors":"Renato da Silva Freitas, Bruna Ferreira Bernert, Isis Juliane Guarezi Nasser, Fabiola Grigoletto Lupion, Eduardo Angeli-Freitas, Cesar Vinícius Grande","doi":"10.1007/s10006-024-01307-1","DOIUrl":"10.1007/s10006-024-01307-1","url":null,"abstract":"Purpose: The objective of this study is to present the largest personal series of oral teratomas already published in English literature and discuss the diagnosis, neonatal management, and surgical treatment of this disorder.Method: The study included patients treated by the senior author (RSF) between 2004 and 2023. Data were collected regarding prenatal evaluation, perinatal approach, surgical management, evolution, and treatment of secondary deformities. In addition, we performed a literature review on the topic.Results: Twelve patients with oral teratoma were included in this study. Seven cases did not have been submitted to any previous treatment, and five cases had already undergone some treatment in another institution. Four cases were diagnosed as epignathus (33.3%), two as true teratomas (16.6%), four as teratoid teratomas (33.3%), one as dermoid teratoma (8.3%) and one as fetus in fetus (8.3%). All patients, except for one, had the tumor surgically removed with good evolution. There was one case of recurrence, successfully operated. The most frequently associated comorbidity was 0-14 fissure, present in 66% of the cases.Conclusion: The experience of our twelve cases indicates that prenatal diagnosis, associated with good multidisciplinary planning of the delivery care, and complete resection of the masses reveal high success rates in the treatment of this pathology.Clinical trial number: This study was performed in line with the principles of the declaration of Helsinki. Approval was granted by the Ethics Committee of Federal University of Paraná - 47102421.2.0000.5225.","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":"29 1","pages":"13"},"PeriodicalIF":1.7,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between condylar surface computed tomography values in the coronal plane and temporomandibular joint disc position in jaw deformity patients: a retrospective study. 下颌畸形患者髁突表面冠状面计算机断层扫描值与颞下颌关节盘位置之间的关联：一项回顾性研究。

IF 1.7

Oral and Maxillofacial Surgery-Heidelberg Pub Date : 2024-11-20 DOI: 10.1007/s10006-024-01308-0

Koichiro Ueki, Karen Gomi Dds, Takahiro Takekawa Dds, Akinori Moroi, Kunio Yoshizawa

{"title":"Association between condylar surface computed tomography values in the coronal plane and temporomandibular joint disc position in jaw deformity patients: a retrospective study.","authors":"Koichiro Ueki, Karen Gomi Dds, Takahiro Takekawa Dds, Akinori Moroi, Kunio Yoshizawa","doi":"10.1007/s10006-024-01308-0","DOIUrl":"10.1007/s10006-024-01308-0","url":null,"abstract":"Objectives: This study aimed to examine the relationship between computed tomography (CT) values of the condylar surface in the coronal plane, condylar morphology and the disc positions in the temporomandibular joint (TMJs) in patients with deformities before and after orthognathic surgery. MATERIALS AND METHODS: The maximum CT values (pixel values) on the condylar surface, condylar thickness, condylar width, condylar angle, condylar height, and joint space were measured. TMJ disc position was classified into five types (anterior type, fully covered type, posterior type, anterior disc displacement with [AW] and without reduction [AWO]), using magnetic resonance imaging (MRI), before and 1 year after surgery. Statistical analysis was performed to assess differences between groups and between the pre- and postoperative values. RESULTS: We enrolled 142 TMJs from 71 female patients diagnosed with jaw deformities. Disc position classification did not change after surgery in all TMJ. Significant differences were observed between anterior displacement (AW and AWO) and other types (fully covered type and posterior type) in the lateral CT value and condylar angle before and 1 year after surgery (P < 0.05). CONCLUSIONS: This study demonstrated a strong relationship between condylar surface CT values in the coronal plane and condylar angle with TMJ disc position classification.","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":"29 1","pages":"12"},"PeriodicalIF":1.7,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Follow-up by telephone questionnaire in outpatient oral and maxillofacial surgery. 通过电话问卷对口腔颌面外科门诊病人进行随访。

IF 1.7

Oral and Maxillofacial Surgery-Heidelberg Pub Date : 2024-11-19 DOI: 10.1007/s10006-024-01305-3

Frizzi Bschorer, Reinhard Bschorer

{"title":"Follow-up by telephone questionnaire in outpatient oral and maxillofacial surgery.","authors":"Frizzi Bschorer, Reinhard Bschorer","doi":"10.1007/s10006-024-01305-3","DOIUrl":"10.1007/s10006-024-01305-3","url":null,"abstract":"Purpose: The SARS-CoV2 pandemic introduced a new problem in postoperative outpatient care: If I set a follow-up appointment at the clinic, will I endanger my patient? This study presents a different way to identify problems in the postoperative setting after outpatient procedures in our field- the telephone interview.Methods: A study nurse conducted the telephone interview using a structured questionnaire within one week of minor outpatient oral and maxillofacial surgery. She asked about pain, swelling, numbness, and mouth opening limitations. Certain red flag answers (numbness, increasing pain, increasing swelling, pain keeping patient from sleeping, pain on swallowing) caused her to book an appointment for the patient in our clinic within the following 24 hours.Results: 52 Patients completed the telephone questionnaire. Of those 3 (5.7%) had red flag answers that resulted in an appointment at the hospital within 24 hours. 2 (3.8%) of them were due to numbness. 24 (46.2%) patients reported no pain. On the numerical rating scale from 0 (no pain) to 10 (worst pain), the average reported pain was 2.24 (SE 0.30). Swelling was reported by 39 (75%) patients. 22 (42.3%) reported the swelling to be mild, 10 (19.2%) moderate, and 7 (13.5%) to be severe. 13 (25%) patients reported a limitation to mouth opening. None reported the interincisal distance to be smaller than one finger.Conclusion: A structured telephone questionnaire can be a useful tool to discern postoperative complications and initiate necessary treatment. At the same time, it minimizes overtreatment. It can be used as a standard tool in the ambulatory treatment. It can be delegated to a secretary or ambulatory nurse with a standardized questionnaire to optimize resource use for selected patients. Moreover, patients describe it as a service to be called at home and they avoid unnecessary travel.","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":"29 1","pages":"11"},"PeriodicalIF":1.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A prospective split-mouth clinical study: comparison of the effect of lornoxicam and etodolac on postoperative sequels following lower third molar surgery. 前瞻性分口临床研究：比较洛诺昔康和依托度酸对下第三磨牙手术后遗症的影响。

IF 1.7

Oral and Maxillofacial Surgery-Heidelberg Pub Date : 2024-11-15 DOI: 10.1007/s10006-024-01309-z

Zulfikar Karabiyik, Mohammad Nabi Basiry

{"title":"A prospective split-mouth clinical study: comparison of the effect of lornoxicam and etodolac on postoperative sequels following lower third molar surgery.","authors":"Zulfikar Karabiyik, Mohammad Nabi Basiry","doi":"10.1007/s10006-024-01309-z","DOIUrl":"10.1007/s10006-024-01309-z","url":null,"abstract":"Purpose: This study aims to compare the efficacy of two non-steroidal anti-inflammatory agents (NSAIDs), namely lornoxicam and etodolac for controlling pain, edema and trismus after removal of lower impacted third molars.Materials and methods: A total of 20 patients comprised of both genders with bilateral impacted lower impacted third molars (in similar positions) was included in the present study. Patients were randomly assigned either to the lornoxicam group (8 mg of lornoxicam) or to the etodolac group (400 mg of etodolac). The drugs prescribed were handed out immediately after tooth extraction. Postoperative pain was assessed using visual analog scale (VAS). Edema was evaluated using reference lines on the face. Trismus was assessed using a caliper at maximum mouth opening (mm).Results: There was no significant difference in postoperative pain, trismus, and edema between lornoxicam and etodolac group (p > 0.05).Conclusions: Based on the results obtained in the present study, ıt has been verified that both lornoxicam and etodolac were adequately effective in the management of pain following third molar surgery. Lornoxicam and etodolac had similar impacts on pain, edema and trismus after impacted lower third molar surgical extractions.","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":"29 1","pages":"10"},"PeriodicalIF":1.7,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142640077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outcomes and prognostic factors in pediatric orbital trapdoor fracture: a multi-center study. 小儿眼眶活瓣骨折的疗效和预后因素：一项多中心研究。

IF 1.7

Oral and Maxillofacial Surgery-Heidelberg Pub Date : 2024-11-06 DOI: 10.1007/s10006-024-01302-6

Bahram Eshraghi, Behzad Khademi, Seyed Mohsen Rafizadeh, Pegah Noorshargh, Alireza Attar, Ali Shahsavari, Sarah Ghorbani

{"title":"Outcomes and prognostic factors in pediatric orbital trapdoor fracture: a multi-center study.","authors":"Bahram Eshraghi, Behzad Khademi, Seyed Mohsen Rafizadeh, Pegah Noorshargh, Alireza Attar, Ali Shahsavari, Sarah Ghorbani","doi":"10.1007/s10006-024-01302-6","DOIUrl":"10.1007/s10006-024-01302-6","url":null,"abstract":"Purpose: To evaluate clinical presentations, computed tomography (CT) findings, and various prognostic factors affecting the surgical outcomes of trapdoor fractures.Methods: This retrospective multi-center study reviewed medical records and orbital CT scans of patients under 21 years old, diagnosed with isolated trapdoor fractures. The study was conducted across multiple medical centers, including emergency and clinical departments in Isfahan, Shiraz, and Tehran-Iran. The characteristics and outcomes following surgical intervention were assessed.Results: 45 patients with isolated trapdoor fractures were included in the study, with a mean age of 11.67 ± 4.69 years, predominantly male (84.4%). Vehicle accidents was the major cause of fractures (31.1%). 44 patients (97.8%) had orbital floor fracture, and one patient (2.2%) had medial wall involvement. Nausea/vomiting were reported in 41 patients (91.1%). Surgical intervention within 2 days, resulted in 85.0% of patients experiencing no postoperative diplopia. Delayed surgery beyond 2 days showed increased odds of diplopia, although not statistically significant. CT scan findings suggested a lower risk of diplopia in patients with soft tissue entrapment compared to muscle involvement (OR: 0.336, 95% CI: 0.077-1.462, p = 0.146). Shorter time to surgery (within 2 days) was significantly associated with normal postoperative eye movements (p = 0.002). Nausea/vomiting were more prevalent in patients with muscle entrapment (p < 0.05).Conclusion: Surgical intervention within 48 h is crucial for improving ocular motility following trapdoor fractures. Extraocular symptoms, including nausea/vomiting, should raise suspicion for trapdoor fractures in cases of orbital trauma associated with ocular movement impairment.Clinical trial number: Not applicable.","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":"29 1","pages":"7"},"PeriodicalIF":1.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Formation of bone tissue apatite on starch-based nanofiber-capped nanohydroxyapatite and reduced graphene oxide: a preliminary study. 在淀粉基纳米纤维包裹的纳米羟基磷灰石和还原氧化石墨烯上形成骨组织磷灰石：初步研究。

IF 1.7

Oral and Maxillofacial Surgery-Heidelberg Pub Date : 2024-11-06 DOI: 10.1007/s10006-024-01303-5

Rethinam Senthil

{"title":"Formation of bone tissue apatite on starch-based nanofiber-capped nanohydroxyapatite and reduced graphene oxide: a preliminary study.","authors":"Rethinam Senthil","doi":"10.1007/s10006-024-01303-5","DOIUrl":"https://doi.org/10.1007/s10006-024-01303-5","url":null,"abstract":"Objectives: In the present study, blends of polyvinyl alcohol (PVA), starch (SH), nanohydroxyapatite (Nano-HA), and reduced graphene oxide (r-GO) were used to fabricate an electrospun nano scaffold (ENS), via electrospinning for their potential application in oral and maxillofacial bone soft and hard tissue regeneration.Materials and methods: The scaffold was characterized for its physicochemical and mechanical properties. An invitro study was carried out using human osteoblast MG-63 bone cells. Surface characterization, particularly the analysis of calcium content, was performed before and after immersion in the simulated body fluid (SBF). Additionally, the impact of surface treatment on antimicrobial activity was investigated.Results: The results demonstrated that the tensile strength (18.12 ± 0.14 MPa), elongation at break (19.23 ± 0.11%), and flexing index (20.15 ± 0.13%) of the ENS were outstanding, indicating promising performance. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assays demonstrated the biocompatible nature of the ENS. The bioactivity test result of ENS showed excellent deposition of bone apatite crystals. The ENS exhibited antimicrobial properties against E. coli (3.41 ± 0.03 mm) and S. aureus (3.12 ± 0.08 mm).Conclusions: The ENS, possessing the desired properties, has the potential to be tested in large animals for oral and maxillofacial bone and soft tissue regeneration after obtaining the necessary approvals. The developed ENS offers a promising solution for bone tissue regeneration in the oral and maxillofacial region.","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":"29 1","pages":"6"},"PeriodicalIF":1.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Allergic clinical symptoms and distribution of stimulation index of drug lymphocyte stimulation test for local anesthetics. 过敏性临床症状与局麻药药物淋巴细胞刺激试验刺激指数的分布。

IF 1.7

Oral and Maxillofacial Surgery-Heidelberg Pub Date : 2024-11-05 DOI: 10.1007/s10006-024-01295-2

Yukiko Baba, Yu Sato, Ken Takahashi, Takaya Ito, Ryo Wakita, Shigeru Maeda

{"title":"Allergic clinical symptoms and distribution of stimulation index of drug lymphocyte stimulation test for local anesthetics.","authors":"Yukiko Baba, Yu Sato, Ken Takahashi, Takaya Ito, Ryo Wakita, Shigeru Maeda","doi":"10.1007/s10006-024-01295-2","DOIUrl":"https://doi.org/10.1007/s10006-024-01295-2","url":null,"abstract":"Objective: The Drug Lymphocyte Stimulation Test (DLST), recognized for its safety as an allergy diagnostic modality, has been acknowledged for its utility in diagnosing drug-induced pathological conditions. However, reports elucidating DLST outcomes concerning local anesthetics are notably scarce.Materials and methods: An exhaustive analysis was conducted on the DLST results pertaining to local anesthetics derived from 571 patients presenting with suspected allergies to these specific agents.Results: Remarkably, Stimulation Index (SI) > 1.8 was discerned in 11.4% and 7.8% of patients exhibiting hives or swelling subsequent to the administration of local anesthetics, surpassing the incidence observed in those experiencing post-injection discomfort. Additionally, SI > 3.0 was observed in 3 cases with lidocaine, 3 cases with prilocaine, and 1 case with mepivacaine. The distribution of SI exhibited a non-normal pattern for all three tested local anesthetics. Noteworthy is the case of a singular patient registering an SI of 1.84, who also yielded a positive challenge test, conclusively confirming an allergy to lidocaine.Conclusions: The DLST, holding promise as a potentially invaluable tool in identifying the causative factors behind adverse reactions to dental local anesthetics, lacks sufficient evidence to substantiate its efficacy definitively at present.Clinical relevance: DLST, coupled with intradermal testing and challenge testing, may be elucidated in patients exhibiting indicators of suspected local anesthetic allergy.","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":"29 1","pages":"5"},"PeriodicalIF":1.7,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0