Clinical Cases in Mineral and Bone Metabolism最新文献_第10页

Craniofacial fibrous dysplasia Report of a case with diverse radiological spectrum. 颅面纤维发育不良1例，影像学表现多样。

Clinical Cases in Mineral and Bone Metabolism Pub Date : 2016-09-01 Epub Date: 2017-02-10 DOI: 10.11138/ccmbm/2016.13.3.249

Silky Rajesh Punyani, Saurabh Srivastava, Vishal Ramesh Jasuja

引用次数: 4

Mesenchymal stem cells in post-surgical cavities of large maxillary bone lesions. 上颌大骨病变术后腔内间充质干细胞的研究。

Clinical Cases in Mineral and Bone Metabolism Pub Date : 2016-09-01 Epub Date: 2017-02-10 DOI: 10.11138/ccmbm/2016.13.3.214

Roberto Bertolai, Carlo Catelani, Mattia Signorini, Alessandro Rossi, Domenico Giannini

{"title":"Mesenchymal stem cells in post-surgical cavities of large maxillary bone lesions.","authors":"Roberto Bertolai, Carlo Catelani, Mattia Signorini, Alessandro Rossi, Domenico Giannini","doi":"10.11138/ccmbm/2016.13.3.214","DOIUrl":"10.11138/ccmbm/2016.13.3.214","url":null,"abstract":"BACKGROUND Recent studies have highlighted that MSCs are capable of regenerating large bone defects when used in combination with bone substitutes and increasing allo-graft osteointegration. We investigated the hypothesis that autologous MSCs may lead to increased bone regeneration and reduced healing time in post-surgical cavities of large maxillary bone lesions. METHODS This study involved 10 patients (TEST GROUP) (6 males and 4 females). All patients had expansive mandibular lesions larger than 3 cm. From the surgical point of view, the 10 patients were treated with MSCs (withdrawal of the iliac crest bone marrow BMMSs) directly into the post-surgical cavity, without the addition of filler. RESULTS and radiological data, in the postoperative, were compared to those of patients who did not receive any grafting of MSCs. The 7 patients with mandibular lesions showed a rapid and very good healing with an 85-90% ossification of the major defect at 12 months. CONCLUSIONS Through the use of stem cells a greater ossification of the residual cavity (85-90%) was observed at 12 months after surgical enucleation in contenitive defects.","PeriodicalId":47230,"journal":{"name":"Clinical Cases in Mineral and Bone Metabolism","volume":"13 3","pages":"214-220"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318175/pdf/214-220.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34756888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The use of routine non density calibrated clinical computed tomography data as a potentially useful screening tool for identifying patients with osteoporosis. 使用常规非密度校准的临床计算机断层扫描数据作为识别骨质疏松症患者的潜在有用的筛查工具。

Clinical Cases in Mineral and Bone Metabolism Pub Date : 2016-05-01 DOI: 10.11138/CCMBM/2016.13.2.135

C. Burke, Manjiri M. Didolkar, H. Barnhart, E. Vinson

{"title":"The use of routine non density calibrated clinical computed tomography data as a potentially useful screening tool for identifying patients with osteoporosis.","authors":"C. Burke, Manjiri M. Didolkar, H. Barnhart, E. Vinson","doi":"10.11138/CCMBM/2016.13.2.135","DOIUrl":"https://doi.org/10.11138/CCMBM/2016.13.2.135","url":null,"abstract":"OBJECTIVES\u0000To evaluate whether lumbar vertebral body density CT attenuation values measured in Hounsfield Units (HUs) on routine Computed Tomography (CT) examinations can be reliably measured with limited variability, and to evaluate for a correlation between HUs and bone mineral density as measured by dual energy X-ray absorptiometry (DXA) scan.\u0000\u0000\u0000METHODS\u0000Retrospective review of a total of 249 routine MDCT examinations, performed to measure HUs at the first non-rib bearing lumbar vertebral body on axial images, cross-referenced to the lateral scout image.\u0000\u0000\u0000RESULTS\u0000The overall ICC and RC for intra-reader variability on CT HU were 0.987 (95% CI 0.973 - 0.999) and 15.664 (95% CI 11.66-16.97). The overall ICC and RDC for inter-reader variability on CT HU were 0.952 (95% CI 0.892 - 0.999) and 30.20 (95% CI 23.73 - 34.48). The ICC and RC for interscanner variability were 0.98 (95% CI 0.95 - 0.99) and 16.67 (95% CI 13.13 - 22.85). The correlation between the L1 HUs and L1 BMD, L1 t-score, and overall t-score was 0.437, 0.392, and 0.400, respectively.\u0000\u0000\u0000CONCLUSIONS\u0000CT attenuation values of the first lumbar vertebra can be measured on routine abdomen CTs with limited variability despite multiple readers and scanners. Correlation between HU and BMD as measured by DXA scan was only weakly positive, and by this method measuring the density of a lumbar vertebral body from a routine MDCT scan does not provide the sensitivity or specificity necessary for a screening test. However above a certain measured value (180 HU), patients have a low chance of osteoporosis and therefore may not need additional screening, potentially limiting radiation exposure and cost.","PeriodicalId":47230,"journal":{"name":"Clinical Cases in Mineral and Bone Metabolism","volume":"1 1","pages":"135-140"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89460488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

Bone healing in 2016. 2016年骨愈合。

Clinical Cases in Mineral and Bone Metabolism Pub Date : 2016-05-01 DOI: 10.11138/CCMBM/2016.13.2.101

J. Buza, T. Einhorn

引用次数: 103

Early onset acute tubular necrosis following single infusion of zoledronate. 单次注射唑来膦酸钠后早发性急性肾小管坏死。

Clinical Cases in Mineral and Bone Metabolism Pub Date : 2016-05-01 DOI: 10.11138/CCMBM/2016.13.2.154

R. Yachoui

引用次数: 5

Hyaluronic acid in the management of osteoarthritis: injection therapies innovations. 透明质酸在骨关节炎的治疗:注射疗法的创新。

Clinical Cases in Mineral and Bone Metabolism Pub Date : 2016-05-01 DOI: 10.11138/CCMBM/2016.13.2.131

V. Santilli, M. Paoloni, M. Mangone, F. Alviti, A. Bernetti

{"title":"Hyaluronic acid in the management of osteoarthritis: injection therapies innovations.","authors":"V. Santilli, M. Paoloni, M. Mangone, F. Alviti, A. Bernetti","doi":"10.11138/CCMBM/2016.13.2.131","DOIUrl":"https://doi.org/10.11138/CCMBM/2016.13.2.131","url":null,"abstract":"Osteoarthritis (OA) is a chronic degenerative joint disease characterized by pain and progressive functional limitation. Viscosupplementation with intra-articular (IA) hyaluronic acid (HA) could be a treatment option in OA, however recommendations made in different international guidelines for the non-surgical management of OA are not always concordant with regard to the role of IA injection therapies. Results from a recent Italian Consensus Conference underline how IA-HA to treat OA represents a widely used therapy in Italy. Specifically high molecular weight HA, cross-linked HA, and mobile reticulum HA are considered very useful to treat the OA joints from a great number of expert in Italy. These kinds of HA could reduce the NSAIDs intake, furthermore high-molecular weight and mobile reticulum HA are considered to be able to delay or avoid a joint prosthetic implant. This mini review highlights the results obtained from the Italian Consensus Conference \"Appropriateness of clinical and organizational criteria for intra-articular injection therapies in osteoarthritis\" and give further indication about innovation in IA-HA therapies.","PeriodicalId":47230,"journal":{"name":"Clinical Cases in Mineral and Bone Metabolism","volume":"33 1","pages":"131-134"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83358878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 31

Bone pain mechanism in osteoporosis: a narrative review. 骨质疏松症的骨痛机制:综述。

Clinical Cases in Mineral and Bone Metabolism Pub Date : 2016-05-01 DOI: 10.11138/CCMBM/2016.13.2.097

C. Mattia, F. Coluzzi, L. Celidonio, R. Vellucci

引用次数: 29

Risk factors of mortality during the first year after low energy osteoporosis fracture: a retrospective case-control study. 低能量骨质疏松性骨折后第一年死亡率的危险因素:回顾性病例对照研究。

Clinical Cases in Mineral and Bone Metabolism Pub Date : 2016-05-01 DOI: 10.11138/CCMBM/2016.13.2.123

Aurore Lloret, G. Coiffier, Tiffen Couchouron, A. Perdriger, P. Guggenbuhl

{"title":"Risk factors of mortality during the first year after low energy osteoporosis fracture: a retrospective case-control study.","authors":"Aurore Lloret, G. Coiffier, Tiffen Couchouron, A. Perdriger, P. Guggenbuhl","doi":"10.11138/CCMBM/2016.13.2.123","DOIUrl":"https://doi.org/10.11138/CCMBM/2016.13.2.123","url":null,"abstract":"INTRODUCTION\u0000Osteoporotic fractures are a major public health problem because of the morbidity and mortality of fracture complications. The objective of this study was to examine predictive factors of mortality during the first year after an osteoporotic fracture.\u0000\u0000\u0000METHODS\u0000It is a retrospective case-control study using data of a group of 1081 patients aged over 50 years with severe osteoporotic fractures by the Rennes university hospital emergency department from August 2007 to September 2008. Patients (cases) who died during the year following the fracture were compared with others who had survived (controls) one year after the fracture, matched on age, sex and type of fracture. Pre-fracture comorbidities and complications after the fractures were studied.\u0000\u0000\u0000RESULTS\u0000Forty-two cases and 126 controls were analyzed without significant differences in age, sex or type of fracture. On univariate analysis, previous neoplasia, neurodegenerative disease, walking aids, thromboembolic complication, post fracture infection, post fracture heart failure, post fracture acute respiratory failure were associated with more mortality after osteoporotic fracture. After multivariate analysis, only previous neoplasia (OR = 4.63 [1.79 - 11.95]; p = 0.02) and acute respiratory failure after fracture (OR = 28.15 [5.75 - 137.9]; p<0.001) were retained as predictive factors during the year following the fracture.\u0000\u0000\u0000CONCLUSION\u0000Patients died more often from their co-morbidities than direct complications of their fractures. Osteoporotic fracture seems to be a marker of poor health status and a factor which may hasten the death.","PeriodicalId":47230,"journal":{"name":"Clinical Cases in Mineral and Bone Metabolism","volume":"32 1","pages":"123-126"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82490874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Concomitant extraspinal hyperostosis and osteoporosis in a patient with congenital ichthyosis. 先天性鱼鳞病患者并发椎管外骨质增生和骨质疏松。

Clinical Cases in Mineral and Bone Metabolism Pub Date : 2016-05-01 DOI: 10.11138/CCMBM/2016.13.2.157

N. Torkamani, P. Phal, R. Savarirayan, P. Simm, G. Varigos, J. Wark

{"title":"Concomitant extraspinal hyperostosis and osteoporosis in a patient with congenital ichthyosis.","authors":"N. Torkamani, P. Phal, R. Savarirayan, P. Simm, G. Varigos, J. Wark","doi":"10.11138/CCMBM/2016.13.2.157","DOIUrl":"https://doi.org/10.11138/CCMBM/2016.13.2.157","url":null,"abstract":"Ichthyosiform dermatosis is a term referred to a group of disorders that have as their basis a disorder of keratinization (1). These conditions which are present at birth result in a generalized dry, scaly skin without any inflammation. There are several types of ichthyosis based on their clinical presentation and mode of inheritance. The most common types are: ichthyosis vulgaris, X-linked recessive ichthyosis, epidermolytic hyperkeratosis (bullous), lamellar ichthyosis and non-bullous ichthyosiform erythroderma. Lamellar ichthyosis, which is inherited in an autosomal recessive pattern, shows genetic heterogeneity with the most severe type being due to mutations in the transglutaminase-1 gene. This condition presents with skin changes at birth and cases are referred to as collodion babies. Initially, the stratum corneum is smooth and appears as though it is covered with cellophane. This layer is discarded a few days after birth, leaving a generalized inflamed and scaly appearance. The skin is tight at this stage and may cause ectropion, and difficulties in feeding and temperature regulation. Lamellar ichthyosis is characterized by plate-like scales that last for life and can significantly impact the patient's quality of life (2). We report here a case of multiple extraspinal hyperostoses concomitant with marked osteoporosis and vitamin D deficiency in a patient taking acitretin for 20 years due to severe congenital lamellar ichthyosis.","PeriodicalId":47230,"journal":{"name":"Clinical Cases in Mineral and Bone Metabolism","volume":"90 5 1","pages":"157-159"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83650140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Underdiagnosis of osteoporotic vertebral fractures in patients with fragility fractures: retrospective analysis of over 300 patients. 脆性骨折患者骨质疏松性椎体骨折的漏诊:300多例患者的回顾性分析

Clinical Cases in Mineral and Bone Metabolism Pub Date : 2016-05-01 DOI: 10.11138/CCMBM/2016.13.2.119

V. Bottai, S. Giannotti, G. Raffaetà, M. Mazzantini, F. Casella, Gaia De Paola, A. Menconi, F. Falossi, G. Guido

引用次数: 17