Luiz Severo Bem Junior, Arthur Lira de Melo, Arthur Oliveira Lira, Denilson Clementino de Pontes, Maria Eduarda Borges Matias, Carlos Cezar Sousa de Lira, Victor Egypto Pereira
{"title":"Spontaneous intracranial hypotension: a case report in the context of differential diagnosis of chronic headaches","authors":"Luiz Severo Bem Junior, Arthur Lira de Melo, Arthur Oliveira Lira, Denilson Clementino de Pontes, Maria Eduarda Borges Matias, Carlos Cezar Sousa de Lira, Victor Egypto Pereira","doi":"10.48208/headachemed.2023.22","DOIUrl":"https://doi.org/10.48208/headachemed.2023.22","url":null,"abstract":"Spontaneous intracranial hypotension (SIH) is a rare and debilitating condition caused by decreased intracranial pressure, which occurs more frequently in females. SIH can have several causes, among them the spontaneous formation of cerebrospinal fluid venous fistula (CSF-venous fistula), which is primarily responsible for the appearance of postural headache. Orthostatic headache is diagnosed by CSF pressure < 6 mmHg associated with specific imaging findings. Other specific symptoms such as dizziness, reduced muscle strength, blurred vision and syncope and other more systemic symptoms such as fatigue, mental confusion and difficulty concentrating are commonly observed. Etiological investigation through imaging studies such as magnetic resonance imaging and dynamic tomography of myelography is necessary for diagnosis. Due to the debilitating condition, several therapeutic approaches have been developed, ranging from more conservative approaches, with observation and use of analgesics, to more invasive interventions such as surgical ligation, transvenous embolization and blood tamponade.","PeriodicalId":472101,"journal":{"name":"Revista Headache Medicine","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134971097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erlene Roberta Ribeiro dos Santos, Amos Lal, Felipe Maia Tardieux, Elayne Cristina de Oliveira Ribeiro, Henry Martins Soares Fortes, Marcelo Moraes Valença
{"title":"External compression headache during Covid-19 pandemic: a neglected entity","authors":"Erlene Roberta Ribeiro dos Santos, Amos Lal, Felipe Maia Tardieux, Elayne Cristina de Oliveira Ribeiro, Henry Martins Soares Fortes, Marcelo Moraes Valença","doi":"10.48208/headachemed.2023.16","DOIUrl":"https://doi.org/10.48208/headachemed.2023.16","url":null,"abstract":"IntroductionPersonal Protective Equipment (PPE) is part of the work routine of health professionals, especially during pandemics. During the Covid-19 pandemic, the use of PPE became constant for long working hours, resulting in adverse effects on the health of professionals, especially headache.ObjectiveIn this review, we explore the scientific literature on headache associated with prolonged use of PPE during the coronavirus pandemic.MethodThis is a narrative literature review conducted through the PubMed and Web of Science databases according to the following MeSH descriptors: “Face shield”, “Headache” and “Covid-19”. Articles that analyzed the presence of headache and other adverse events in health professionals in prolonged use of PPE were included.ResultsThe included studies point to headache as the most prevalent adverse event, which may be a new headache or the worsening of a previous headache. Other effects were also found, such as pressure marks on the skin, hyperemia in contact areas; suffocation; reduced concentration and excessive sweating.ConclusionThe use of PPE for long periods can cause headaches due to external pressure, in addition to other unwanted events.These effects reveal the importance of studies to make PPE more efficient, ensuring protection for the individual without causing discomfort.","PeriodicalId":472101,"journal":{"name":"Revista Headache Medicine","volume":"218 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134971095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Insights on the terminology and on some pathophysiological aspects of cluster headache and related conditions","authors":"Carlos Alberto Bordini","doi":"10.48208/headachemed.2023.24","DOIUrl":"https://doi.org/10.48208/headachemed.2023.24","url":null,"abstract":"IntroductionCluster headache and the more recently reported “related conditions”, namelyChronic Paroxysmal Hemicrania, Short-lasting, unilateral, Neuralgiform Headachewith Conjunctival Injection and Tearing (SUNCT) Syndrome and (possibly also)Hemicrania Continua, are one of the fascinating groups of conditions in Neurologywhose cardinal features are the almost absolute unilaterality of pain, its excruciatingseverity, besides the prominent mainly facial autonomic disturbances and overall theintriguing biorhythmicity.Beyond any doubt, the progress of our knowledge about themechanisms of these conditions has been considerable, but there is always room forreflection on where we are and where we can go.ObjectiveThe objectives of the present study are to analyze the metrics of publications onthe pathophysiology of these conditions, to explore in detail how proper the term”Trigeminal Autonomic Cephalgia” is, and to comment on their numerous synonyms.CommentMuch is needed to know the exact structures and circuitry involved in the pathophysiology of these conditions; accordingly, a non-compromising and just descriptive termmight be useful. Along this line of reasoning and bearing in mind the cardinal pointsof such conditions, namely, pain in the trigeminal territory, prominent autonomicsymptoms, prominent chronobiological features, and the excruciating character ofthe pain, a terminological possibility would be: Unilateral with Prominent Rhythmicityand Autonomic Symptoms Excrutiating Cephalgia (UPRASEC).","PeriodicalId":472101,"journal":{"name":"Revista Headache Medicine","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134971098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Atypical Hypersensitivity Reaction to Botulinum Toxin Injection","authors":"Joe Ghorayeb, Timithy McClellan, Kelley Crozier","doi":"10.48208/headachemed.2023.21","DOIUrl":"https://doi.org/10.48208/headachemed.2023.21","url":null,"abstract":"Botulinum toxin type A (BTA) injection, marketed as BOTOX, is commonly used as a treatment for a variety of clinical indications and is widely viewed as safe, effective and largely devoid of serious side effects. Anaphylactic reactions to BTA are typically unheard of in the scientific literature. BOTOX is approved by the Food and Drug Administration for the treatment of cervical dystonia and prophylaxis for chronic migraines. This case report documents a unique instance of allergic reaction to BTA in a 29-year-old woman with cervicogenic headache and cervical dystonia who reported immediate flushing, light-headedness and nausea after receiving BTA injections.","PeriodicalId":472101,"journal":{"name":"Revista Headache Medicine","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136300673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Avaliação do uso de anticorpos monoclonais (mAbs) CGRP na profilaxia da enxaqueca em uma clínica privada","authors":"Natalia Farenzena, Alan Christmann Fröhlich","doi":"10.48208/headachemed.2023.17","DOIUrl":"https://doi.org/10.48208/headachemed.2023.17","url":null,"abstract":"IntroduçãoA enxaqueca é considerada o segundo distúrbio neurológico mais prevalente na população e altamente incapacitante. ObjetivoO objetivo deste estudo é avaliar o uso de anticorpos monoclonais do peptídeo relacionado ao gene da calcitonina (CGRP) na profilaxia da enxaqueca, com ênfase na resposta terapêutica, efeitos adversos e impactos na qualidade de vida.MétodoFoi realizado um estudo quantitativo, retrospectivo e descritivo, por meio da análise de prontuários e entrevistas telefônicas com pacientes atendidos no Serviço de Neurologia e Neurocirurgia, na cidade de Passo Fundo, RGS, Brasil, que já utilizaram ou utilizaram pelo menos uma dose do medicamento.ConclusãoAssim, entende-se que os anticorpos monoclonais CGRP são capazes de reduzir os dias mensais de cefaléia, reduzir a intensidade da dor e promover melhora na capacidade laboral. Portanto, podem ser considerados medicamentos eficazes, seguros e de boa adesão na profilaxia da enxaqueca.","PeriodicalId":472101,"journal":{"name":"Revista Headache Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136300675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Calcitonin gene-related peptide (CGRP) concentrations outside migraine attacks in peripheral blood as a potential biomarker for chronic migraine","authors":"Showkat hassan Bhat, RAVOUF ASIMI, Zaffar amin Shah, ADNAN FIRDOUS RAINA","doi":"10.48208/headachemed.2023.18","DOIUrl":"https://doi.org/10.48208/headachemed.2023.18","url":null,"abstract":"Abstract Introduction Chronic migraine is a debilitating condition that affects a significant portion of the population. Accurate diagnosis and treatment of chronic migraine remain a challenge due to the lack of objective biomarkers. Calcitonin gene-related peptide (CGRP) is a neuropeptide involved in the pathophysiology of migraine and has been proposed as a potential biomarker for migraine. Methods We measured CGRP levels in peripheral blood samples collected from 142 participants with chronic or episodic migraine and 24 healthy controls during ictal periods, i.e., outside migraine attacks. We compared CGRP levels between the three groups and assessed the correlation between CGRP levels and clinical features of chronic migraine. Conclusion Our study provides evidence that CGRP levels in peripheral blood during ictal periods may serve as a potential biomarker for chronic migraine. Further studies are needed to validate these findings and to explore the clinical utility of CGRP as a biomarker for chronic migraine.","PeriodicalId":472101,"journal":{"name":"Revista Headache Medicine","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136300674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}