Medicinska istraživanja最新文献_第2页

Prof. dr Đorđe Joannović, a corresponding member of Serbian Royal Academy, Dean, pathologist and the first Serbian oncologist, one of the world pioneers of the study of autoaggression, the founder and builder of the Institute of Pathology, the most tragic personality in the one-century-long history of the Faculty of Medicine: 151 years since birth and 90 years since death Đorđe joannovivic博士教授，塞尔维亚皇家科学院通讯委员，院长，病理学家和第一位塞尔维亚肿瘤学家，世界上研究自身攻击的先驱之一，病理研究所的创始人和建造者，医学院百年历史上最悲惨的人物:出生151年，死亡90年

Medicinska istraživanja Pub Date : 2023-01-01 DOI: 10.5937/medi56-42826

Vladimir Kanjuh, Sanja Radojević-Škodrić, Lazar Davidović, Nebojša Lalić

引用次数: 1

Complex karyotype in chronic lymphocytic leukemia 慢性淋巴细胞白血病的复杂核型

Medicinska istraživanja Pub Date : 2023-01-01 DOI: 10.5937/medi56-45003

Darko Antić, Sofija Kozarac, Kristina Tomić-Vujović, Vladimir Otašević, Andrej Pešić, Vojin Vuković, Biljana Mihaljević

引用次数: 0

Implications of COVID-19 pandemic on laparoscopic and abdominal surgery for benign adnexal conditions: Single center experience COVID-19大流行对良性附件疾病腹腔镜和腹部手术的影响:单中心经验

Medicinska istraživanja Pub Date : 2023-01-01 DOI: 10.5937/medi56-42044

Milan Dokić, Branislav Milošević, Jelena Dotlić, Teodora Đerić, Luka Andrić, Sandra Babić, Dragiša Šljivančanin

{"title":"Implications of COVID-19 pandemic on laparoscopic and abdominal surgery for benign adnexal conditions: Single center experience","authors":"Milan Dokić, Branislav Milošević, Jelena Dotlić, Teodora Đerić, Luka Andrić, Sandra Babić, Dragiša Šljivančanin","doi":"10.5937/medi56-42044","DOIUrl":"https://doi.org/10.5937/medi56-42044","url":null,"abstract":"Introduction/Aim: COVID-19 pandemic posed a challenge in patient treatment and caused problems in the organization of health systems in many countries. The study aimed to analyze and quantify the influence of COVID-19 pandemic on performing surgeries for benign adnexal conditions with classic (open abdominal) and minimally invasive (laparoscopic) approach at the Clinic for Gynecology and Obstetrics University Clinical Center of Serbia. Material and Methods: The study retrospectively analyzed all patients who were operated due to benign adnexal masses at our Clinic during the past five years. We compared numbers and types of operations before and during the pandemic. Results: The study included 2166 patients who significantly more often had laparoscopic (61.9%) than open surgeries (38.1%). Surgeries of benign adnexal masses were elective in 53.2% cases, whereas in 46.8% cases those were emergency surgeries. Before the pandemic laparoscopic surgeries (mostly cystectomies) were on the rise. A reduction in laparoscopic and open surgeries was seen in the year 2020 (p=0.001). Moreover, the majority of surgeries were emergency surgeries (76.2%; p=0.001). Nevertheless, this decrease was significant only for laparoscopic cystectomies (p=0.001), but not for adnexectomies (p=0.224) and salpingectomies (p=0.762). Likewise, the 2020 reduction in open cystectomies (p=0.073), adnexectomies (p=0.836) and salpingectomies (p=0.241) was not significant either. During 2021, the number of surgical procedures for benign adnexal masses started to rise again (p=0.023). No intra-hospital COVID-19 infections were registered. Conclusion: The total number of operations of benign adnexal masses in our Clinic decreased and was limited to emergencies, which was mostly reflected in minimally invasive surgery.","PeriodicalId":471485,"journal":{"name":"Medicinska istraživanja","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136306188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term survival after heart transplantation: The experience of the Republic of Serbia heart transplantation program 心脏移植后的长期生存:塞尔维亚共和国心脏移植项目的经验

Medicinska istraživanja Pub Date : 2023-01-01 DOI: 10.5937/medi56-43160

Milos Matković, Emilija Nestorović, Ilija Bilbija, Nemanja Aleksić, Dejan Marković, Svetozar Putnik

{"title":"Long-term survival after heart transplantation: The experience of the Republic of Serbia heart transplantation program","authors":"Milos Matković, Emilija Nestorović, Ilija Bilbija, Nemanja Aleksić, Dejan Marković, Svetozar Putnik","doi":"10.5937/medi56-43160","DOIUrl":"https://doi.org/10.5937/medi56-43160","url":null,"abstract":"Introduction/Aim: Heart transplantation (HTX) is the gold standard for the treatment of patients in symptomatic terminal stadium of heart failure. This study aimed to investigate the long-term results of the HTX and to determine the independent survival predictors after HTX within The Serbian Heart Transplantation program. Methods: A retrospective observational study was performed. The study included 44 patients that were subjected to heart transplantation from 2013 to 2021 within the The Serbian Heart Transplantation program. All the patients were included in the National heart transplantation waiting list according to the contemporary ISHLT criteria. The study included all the patients subjected to HTX, as well as the ones who received long-term circulatory support preoperatively. The data were obtained from the medical history records and follow-up visits. Results: The average survival of all patients was 1611.8 days (1306.9 - 1916.7). The median length of patient follow-up was 637.4 days (1-2028 days). Six-year patient survival was 70.5%. Cox's regression analysis determined that independent predictors of worse outcome were as follows: age of the recipient, body mass index of the recipient, previous CVI, preoperative chronic renal insufficiency, pulmonary hypertension, infection in the postoperative course, as well as the need for mechanical circulatory support in the immediate postoperative course. Conclusion: The Serbian Heart Transplantation program demonstrated the survival rate comparable to the HTX centers worldwide and in ISHLT registry. The independent risk factors should be carefully analyzed for our study population and taken into consideration when planning the procedure.","PeriodicalId":471485,"journal":{"name":"Medicinska istraživanja","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136306181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hippocampal sclerosis 海马硬化

Medicinska istraživanja Pub Date : 2023-01-01 DOI: 10.5937/medi56-43743

Aleksandar Ristić, Savo Raičević, Vladimir Baščarević, Nikola Vojvodić, Dragoslav Sokić

{"title":"Hippocampal sclerosis","authors":"Aleksandar Ristić, Savo Raičević, Vladimir Baščarević, Nikola Vojvodić, Dragoslav Sokić","doi":"10.5937/medi56-43743","DOIUrl":"https://doi.org/10.5937/medi56-43743","url":null,"abstract":"Hippocampal sclerosis is one of the most common causes of focal epilepsy. At the same time, hippocampal sclerosis is the most common surgical substrate in focal pharmacoresistant epilepsies. The hippocampus has a specific anatomical structure consisting of a total of four sectors. In a physiological context, the hippocampus is essential in many neuropsychological processes, so hippocampal sclerosis (an entity recognized and associated with epilepsy as early as the 19th century) is very interesting in terms of research. The pathohistological pattern of hippocampal sclerosis is now very precisely represented, which helps uniform recognition. The causes of hippocampal sclerosis are not known, but so far, numerous factors have been identified that are associated with the occurrence of this pathological process. There is no doubt that excitotoxicity, along with changes in the redox system, is the most essential pathophysiological mechanism. Hippocampal sclerosis is clinically very recognizable. Epilepsy patients whose basis is hippocampal sclerosis have very typical epileptic seizures consisting of an epigastric aura followed by a focal epileptic seizure characterized by confusion of consciousness and oroalimentary automatisms. Today, thanks to modern neuroimaging (primarily magnetic resonance imaging), the detection of this pathological pattern is exact and unambiguous.","PeriodicalId":471485,"journal":{"name":"Medicinska istraživanja","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136306350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0